arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 2011.04736physics.med-ph
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FastCAT:快速锥束CT(CBCT)模拟

FastCAT: Fast Cone Beam CT (CBCT) Simulation

Jericho O'Connell, Magdalena Bazalova-Carter

摘要:

fastCAT应用程序使用预先计算的Monte Carlo(MC)CBCT体模特定散射和探测器响应函数,以减少兆伏(MV)和千伏(kV)CBCT成像的模拟时间。将预先计算的X射线束能量谱、探测器光学扩散函数和能量沉积以及体模散射内核与GPU射线跟踪相结合,以产生CBCT体积。使用EGSnrc模拟了入射到各种靶材料上的2.5和6 MeV电子束的MV X射线束谱,并解析计算了具有钨阳极的X射线管的kV X射线束谱。探测器在Topas扩展的Geant 4中建模,并在反射器中包括光学传输。两个MV探测器,一个标准的Varian AS 1200 GOS探测器和一个新的CWO高检测量子效率探测器建模。kV CsI探测器也被建模。在Topas中为两个直径为16 cm的体模创建了能量相关散射核:Catphan 515造影体模和拟人头部体模。Catphan体模包含六种不同组织类型的直径为1-5 mm的插入物。FastCAT模拟保持了对测量和MC模拟的高保真度:CWO和GOS探测器的MTF曲线分别在测量值的3.5%和1.2%以内。对于所有组织,fastCAT Catphan 515模拟中的HU值和CNR均在等效MC模拟的95%置信区间内,HU值和CNR比较的均方根误差分别小于16 HU和1.6。Catphan 515模块的fastCAT模拟(图像大小为1024 x1024 x10体素)在GPU上花费了61秒,而等效的Topas MC估计需要超过0.3 CPU年。fastCAT应用程序可以在https://github.com/jerichooconnell/fastCATs.git上找到。

英文摘要:

The fastCAT application uses pre-calculated Monte Carlo (MC) CBCT phantom-specific scatter and detector response functions to reduce simulation time for megavoltage (MV) and kilovoltage (kV) CBCT imaging. Pre-calculated x-ray beam energy spectra, detector optical spread functions and energy deposition, and phantom scatter kernels are combined with GPU raytracing to produce CBCT volumes. MV x-ray beam spectra are simulated with EGSnrc for 2.5 and 6 MeV electron beams incident on a variety of target materials and kV x-ray beam spectra are calculated analytically for an x-ray tube with a tungsten anode. Detectors were modelled in Geant4 extended by Topas and included optical transport in the scintillators. Two MV detectors were modelled, a standard Varian AS1200 GOS detector and a novel CWO high detective quantum efficiency detector. A kV CsI detector was also modelled. Energy dependent scatter kernels were created in Topas for two 16-cm diameter phantoms: A Catphan 515 contrast phantom and an anthropomorphic head phantom. The Catphan phantom contained inserts of 1-5 mm in diameter of six different tissue types. FastCAT simulations retain high fidelity to measurements and MC simulations: MTF curves were within 3.5% and 1.2% of measured values for the CWO and GOS detectors, respectively. HU values and CNR in a fastCAT Catphan 515 simulation were seen to be within 95 % confidence intervals of an equivalent MC simulation for all of the tissues with root mean squared errors less than 16 HU and 1.6 in HU values and CNR comparisons, respectively. A fastCAT simulation of the Catphan 515 module with an image size of 1024x1024x10 voxels took 61 seconds on a GPU while the equivalent Topas MC was estimated to take more than 0.3 CPU years. The fastCAT application can be found at https://github.com/jerichooconnell/fastCATs.git.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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