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arXiv 1109.5124math.PRq-bio.PE
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病毒存活的一个分支过程

A Branching Process for Virus Survival

J. Theodore Cox, Rinaldo B. Schinazi

摘要:

准种理论预测,存在一个临界突变概率,超过这个概率,病毒种群就会灭绝。超过这个阈值,病毒失去复制最佳适应基因型的能力,导致由低复制突变体组成的种群最终注定失败。我们提出了一个新的分支模型,表明这是不一定如此。也就是说,一个由不断变化的突变体组成的种群可能会生存下来。

英文摘要:

Quasispecies theory predicts that there is a critical mutation probability above which a viral population will go extinct. Above this threshold the virus loses the ability to replicate the best adapted genotype, leading to a population composed of low replicating mutants that is eventually doomed. We propose a new branching model that shows that this is not necessarily so. That is, a population composed of ever changing mutants may survive.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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