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arXiv 1505.04656q-bio.OTphysics.bio-ph
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遗传密码的四元数表示

Quaternionic representation of the genetic code

C. Manuel Carlevaro, Ramiro M. Irastorza, Fernando Vericat

摘要:

给出了标准遗传密码演化的启发式图。它以类似于原子能级的方式纳入了对称性破缺的物理概念,并且与克里克关于密码起源和进化的原始想法以及氨基酸沿进化出现的时间顺序一致,这是从已知实验结果与理论推测混合的工作中推断出来的。根据图表的建议,我们提出了一个基于Hamilton四元数的代码数学表示,因为它现在是一天。本说明书的中心目标是一个密码子函数,该函数为每个氨基酸分配一个整数四元数,以保持观察到的密码子退化。我们强调的优点,四元数表示的氨基酸作为一个例子,折叠的蛋白质。有了这个目标,我们提出了一个算法去从四元数序列的蛋白质的三维结构,可以与相应的实验存储在蛋白质数据库。在我们的标准中,遗传密码的数学表示在四元数方面的优点被考虑在内,因为它不仅描述了遗传密码的大多数已知属性,而且还打开了新的视角,主要来自四元数和旋转之间的密切关系。

英文摘要:

A heuristic diagram of the evolution of the standard genetic code is presented. It incorporates, in a way that resembles the energy levels of an atom, the physical notion of broken symmetry and it is consistent with original ideas by Crick on the origin and evolution of the code as well as with the chronological order of appearence of the amino acids along the evolution as inferred from work that mixtures known experimental results with theoretical speculations. Suggested by the diagram we propose a Hamilton quaternions based mathematical representation of the code as it stands now-a-days. The central object in the description is a codon function that assigns to each amino acid an integer quaternion in such a way that the observed code degeneration is preserved. We emphasize the advantages of a quaternionic representation of amino acids taking as an example the folding of proteins. With this aim we propose an algorithm to go from the quaternions sequence to the protein three dimensional structure which can be compared with the corresponding experimental one stored at the Protein Data Bank. In our criterion the mathematical representation of the genetic code in terms of quaternions merits to be taken into account because it describes not only most of the known properties of the genetic code but also opens new perspectives that are mainly derived from the close relationship between quaternions and rotations.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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