利用GEANT4工具包研究轻核在类组织介质中碎裂产生的中子
Neutrons from fragmentation of light nuclei in tissue-like media: a study with GEANT4 toolkit
摘要：
我们研究了轻核在组织样介质中的能量沉积，同时考虑了核碎裂反应，特别是次级中子的产生。在基于GEANT 4工具包的重离子治疗（MCHIT）蒙特卡罗模型内进行计算。对135 A-400 A MeV C-12和O-18束的深度-剂量分布的实验数据进行了很好的描述，而无需对模型参数进行任何调整。这为成功使用GEANT 4工具包进行光核束癌症治疗的MC模拟提供了信心。C-1 - 2和Ne-20射束在（40-50 cm）^[3]水模体中产生的次级中子引起的能量沉积估计为总剂量的1-2%，仅略高于200 MeV质子射束引起的中子贡献（~1%）。
英文摘要：
We study energy deposition by light nuclei in tissue-like media taking into account nuclear fragmentation reactions, in particular, production of secondary neutrons. The calculations are carried out within a Monte Carlo model for Heavy-Ion Therapy (MCHIT) based on the GEANT4 toolkit. Experimental data on depth-dose distributions for 135A-400A MeV C-12 and O-18 beams are described very well without any adjustment of the model parameters. This gives confidence in successful use of the GEANT4 toolkit for MC simulations of cancer therapy with beams of light nuclei. The energy deposition due to secondary neutrons produced by C-12 and Ne-20 beams in a (40-50 cm)^3 water phantom is estimated to 1-2% of the total dose, that is only slightly above the neutron contribution (~1%) induced by a 200 MeV proton beam.
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