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arXiv 2408.08039physics.opticsphysics.app-ph

面向中红外芯片实验室系统的优化波导:一种严谨的设计方法

Optimized waveguides for mid-infrared lab-on-chip systems: A rigorous design approach

Antonia Torres-Cubillo, Andrea Teuber, Robert Halir, Boris Mizaikoff

AI总结:

针对中红外芯片实验室波导缺乏统一设计方法、难以公平比较不同材料方案的问题,本研究提出系统波导设计方法,可通过参数化表达式比较多种前沿薄膜波导的检测限并给出最优尺寸参数,助力下一代器件开发。

摘要:

中红外吸收光谱是一种成熟的无损定量分子分析技术。集成波导的传感器提供了一种尤为紧凑的解决方案,可使用更少的样本量运行,同时具备出色的分子选择性、灵敏度和超低检测限。中红外技术的最新进展,加上片上光源、探测器和微流控技术的集成,让中红外芯片实验室系统更接近现实。目前已提出多种材料平台用于实现这类系统。然而,由于缺乏统一的波导设计方法,难以对不同方案进行公平比较,也难以进行审慎的材料选择,这限制了优化型片上光谱器件的发展。本研究开发了一套系统的波导设计方法,可用于基于倏逝场吸收的传感,尤其适用于水基分析物。我们的策略能够利用参数化表达式预测传感系统可达到的检测限,从而对多种前沿薄膜波导进行严谨比较,同时给出最优波导尺寸和吸收路径长度,这对下一代中红外芯片实验室器件的开发至关重要。

英文摘要:

Mid-infrared absorption spectroscopy is a well-established technique for non-destructive quantitative molecular analysis. Waveguide-integrated sensors provide a particularly compact solution operating with reduced sample volumes while exhibiting exquisite molecular selectivity, sensitivity, and ultra-low limits of detection. Recent advances in mid-infrared technologies along with the integration of on-chip sources, detectors and microfluidics, have brought mid-infrared lab-on-chip systems closer to reality. A variety of material platforms has been proposed for the implementation of such systems. However, the lack of a consistent waveguide design approach renders a fair comparison between different alternatives - and a deliberate material selection - challenging, limiting the development of optimized on-chip spectroscopic devices. In the present study, a systematic waveguide design approach has been developed, facilitating evanescent field absorption-based sensing, in particular for aqueous analytes. Our strategy enables a rigorous comparison of several state-of-the-art thin-film waveguides using parametric expressions to predict the achievable limits of detection of the sensing system, while indicating optimum waveguide dimensions and absorption pathlengths, pivotal for the development of next-generation mid-infrared lab-on-chip devices.

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