Since cadiovascular disease (CVD) posts a heavy threat to people's health, long-term electrocardiogram (ECG) monitoring is of great value for the improvement of treatment. To realize remote long-term ECG monitoring, a low-power wireless wearable ECG monitoring device is proposed in this paper. The ECG monitoring device, abbreviated as ECGM, is designed based on ferroelectric microprocessor which provides ultra-low power consumption and contains four parts-MCU, BLE, Sensors and Power. The MCU part means circuit of MSP430FR2433, the core of ECGM. The BLE part is the CC2640R2F module applied for wireless transmission of the collected bio-signal data. And the sensors part includes several sensors like BMD101 used for monitoring bio-signals and motion of the wearer, while the Power part consists of battery circuit, charging circuit and 3.3V/1.8V/4.4V power supply circuit. The ECGM first collects ECG signals from the fabric electrodes adhered to wearers' chest, preprocesses the signals to eliminate the injected noise, and then transmit the output data to wearers' hand-held mobile phones through Bluetooth low energy (BLE). The wearers are enabled to acquire ECGs and other physiological parameters on their phones as well as some corresponding suggestions. The novelty of the system lies in the combination of low-power ECG sensor chip with ferroelectric microprocessor, thus achieving ultra-low power consumption and high signal quality.
The Chinese University of Hong Kong（香港中文大学）；Institute of Future Cities, The Chinese University of Hong Kong（香港中文大学未来城市研究所）；Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong（香港中文大学李嘉诚健康科学研究所）
Cardiovascular diseases (CVDs) are the number one cause of death worldwide. While there is growing evidence that the atrial fibrillation (AF) has strong associations with various CVDs, this heart arrhythmia is usually diagnosed using electrocardiography (ECG) which is a risk-free, non-intrusive, and cost-efficient tool. Continuously and remotely monitoring the subjects' ECG information unlocks the potentials of prompt pre-diagnosis and timely pre-treatment of AF before the development of any life-threatening conditions/diseases. Ultimately, the CVDs associated mortality could be reduced. In th…
Heartbeat classification using electrocardiogram (ECG) data is a vital assistive technology for wearable health solutions. We propose heartbeat feature classification based on a novel sparse representation using time-frequency joint distribution of ECG. Fundamental to this is a multi-layer perceptron, which incorporates these signatures to detect cardiac arrhythmia. This approach is validated with ECG data from MIT-BIH arrhythmia database. Results show that our approach has an average 95.7% accuracy, an improvement of 22% over state-of-the-art approaches. Additionally, ECG sparse distributed r…
Objective: A novel ECG classification algorithm is proposed for continuous cardiac monitoring on wearable devices with limited processing capacity. Methods: The proposed solution employs a novel architecture consisting of wavelet transform and multiple LSTM recurrent neural networks. Results: Experimental evaluations show superior ECG classification performance compared to previous works. Measurements on different hardware platforms show the proposed algorithm meets timing requirements for continuous and real-time execution on wearable devices. Conclusion: In contrast to many compute-intensive…
This paper presents a novel ECG classification algorithm for real-time cardiac monitoring on ultra low-power wearable devices. The proposed solution is based on spiking neural networks which are the third generation of neural networks. In specific, we employ spike-timing dependent plasticity (STDP), and reward-modulated STDP (R-STDP), in which the model weights are trained according to the timings of spike signals, and reward or punishment signals. Experiments show that the proposed solution is suitable for real-time operation, achieves comparable accuracy with respect to previous methods, and…
Objective: Continuous monitoring of biosignals via wearable sensors has quickly expanded in the medical and wellness fields. At rest, automatic detection of vital parameters is generally accurate. However, in conditions such as high-intensity exercise, sudden physiological changes occur to the signals, compromising the robustness of standard algorithms. Methods: Our method, called BayeSlope, is based on unsupervised learning, Bayesian filtering, and non-linear normalization to enhance and correctly detect the R peaks according to their expected positions in the ECG. Furthermore, as BayeSlope i…
Cardiovascular disease has become one of the most significant threats endangering human life and health. Recently, Electrocardiogram (ECG) monitoring has been transformed into remote cardiac monitoring by Holter surveillance. However, the widely used Holter can bring a great deal of discomfort and inconvenience to the individuals who carry them. We developed a new wireless ECG patch in this work and applied a deep learning framework based on the Convolutional Neural Network (CNN) and Long Short-term Memory (LSTM) models. However, we find that the models using the existing techniques are not ab…
CarDS-Plus ECG Platform: Development and Feasibility Evaluation of a Multiplatform Artificial Intelligence Toolkit for Portable and Wearable Device Electrocardiograms
Yale School of Medicine（耶鲁医学院）；Yale New Haven Hospital（耶鲁-纽黑文医院）；Yale School of Public Health（耶鲁公共卫生学院）
University College Dublin（都柏林大学学院）；National University of Singapore（新加坡国立大学）
Sudden cardiac death and arrhythmia account for a large percentage of all deaths worldwide. Electrocardiography (ECG) is the most widely used screening tool for cardiovascular diseases. Traditionally, ECG signals are classified manually, requiring experience and great skill, while being time-consuming and prone to error. Thus machine learning algorithms have been widely adopted because of their ability to perform complex data analysis. Features derived from the points of interest in ECG - mainly Q, R, and S, are widely used for arrhythmia detection. In this work, we demonstrate improved perfor…
Personalized Deep Learning for Short-Term Forecasting of Impending Atrial Fibrillation from Continuous Wearable ECG Signals
Seoul National University（首尔大学）；CHA Bundang Medical Center and CHA University School of Medicine（CHA板桥医疗中心和CHA大学医学院）；SEERS Technology Co., Ltd（SEERS科技有限公司）；Department of Internal Medicine, Seoul National University College of Medicine and Seoul National University Hospital（首尔大学医学院内科学系和首尔大学医院）
University Medical Center Hamburg-Eppendorf (UKE)（汉堡-埃彭多夫大学医学中心（UKE））；Jacobs University gGmbH（雅各布大学gGmbH）
The reservoir computing paradigm is employed to classify heartbeat anomalies online based on electrocardiogram signals. Inspired by the principles of information processing in the brain, reservoir computing provides a framework to design, train, and analyze recurrent neural networks (RNNs) for processing time-dependent information. Due to its computational efficiency and the fact that training amounts to a simple linear regression, this supervised learning algorithm has been variously considered as a strategy to implement useful computations not only on digital computers but also on emerging u…
University of North Carolina（北卡罗来纳大学）；George Washington University（乔治·华盛顿大学）
Breathing rate (BR), minute ventilation (VE), and other respiratory parameters are essential for real-time patient monitoring in many acute health conditions, such as asthma. The clinical standard for measuring respiration, namely Spirometry, is hardly suitable for continuous use. Wearables can track many physiological signals, like ECG and motion, yet not respiration. Deriving respiration from other modalities has become an area of active research. In this work, we infer respiratory parameters from wearable ECG and wrist motion signals. We propose a modular and generalizable classification-re…
In this paper, we present a wireless ECG-derived Respiration Rate (RR) estimation using an autoencoder with a DCT Layer. The wireless wearable system records the ECG data of the subject and the respiration rate is determined from the variations in the baseline level of the ECG data. A straightforward Fourier analysis of the ECG data obtained using the wireless wearable system may lead to incorrect results due to uneven breathing. To improve the estimation precision, we propose a neural network that uses a novel Discrete Cosine Transform (DCT) layer to denoise and decorrelates the data. The DCT…
Cardiac abnormalities affecting heart rate and rhythm are commonly observed in both healthy and acutely unwell people. Although many of these are benign, they can sometimes indicate a serious health risk. ECG monitors are typically used to detect these events in electrical heart activity, however they are impractical for continuous long-term use. In contrast, current-generation wearables with optical photoplethysmography (PPG) have gained popularity with their low-cost, lack of wires and tiny size. Many cardiac abnormalities such as ectopic beats and AF can manifest as both obvious and subtle …
National Institute of Health Data Science, Peking University（北京大学健康数据科学国家研究院）；Department of Cardiology, Peking University People’s Hospital（北京大学人民医院心内科）；Institute of Medical Technology, Peking University Health Science Center（北京大学医学部医学技术学院）；Tianjin Key Laboratory of lonic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University（天津医科大学第二医院心脏研究所心内科离子-分子心血管功能天津市重点实验室）
The recent developments in wearable devices and the Internet of Medical Things (IoMT) allow real-time monitoring and recording of electrocardiogram (ECG) signals. However, continuous monitoring of ECG signals is challenging in low-power wearable devices due to energy and memory constraints. Therefore, in this paper, we present a novel and energy-efficient methodology for continuously monitoring the heart for low-power wearable devices. The proposed methodology is composed of three different layers: 1) a Noise/Artifact detection layer to grade the quality of the ECG signals; 2) a Normal/Abnorma…
Lightweight MobileNetV1+GRU for ECG Biometric Authentication: Federated and Adversarial Evaluation
Department of Computer Science \& Information Technology IoST, Tribhuwan University, Nepal；Department of Electronics；Computer Engineering Institute of Engineering, Dharan, Nepal
This paper describes an open-access database focusing on the study of mental workload (MW) assessment system for wearable devices. A wristband photoplethysmogram (PPG) was provided as a representative of wearable devices. In addition, a clinical device that can record Electrocardiography (ECG) , galvanic skin response (GSR) and, fingertip PPG was included in the database as a reference. The MW was induced by performing the N-back task with 22 subjects. The participants were asked to answer the Pittsburgh Sleep Quality Index (PSQI) questionnaire at the beginning of the experiment and the NASA T…
PPGFlowECG: Latent Rectified Flow with Cross-Modal Encoding for PPG-Guided ECG Generation and Cardiovascular Disease Detection
National Institute of Health Data Science, Peking University, China（北京大学国家健康数据科学研究院）；School of Intelligence Science and Technology, Peking University, China（北京大学智能科学与技术学院）；Data Science Institute, Imperial College London, UK（伦敦帝国理工学院数据科学研究院）；University of Chinese Academy of Sciences, China（中国科学院大学）
Queen’s University（女王大学）；Ingenuity Labs Research Institute（创新实验室研究所）
Classification of human emotions can play an essential role in the design and improvement of human-machine systems. While individual biological signals such as Electrocardiogram (ECG) and Electrodermal Activity (EDA) have been widely used for emotion recognition with machine learning methods, multimodal approaches generally fuse extracted features or final classification/regression results to boost performance. To enhance multimodal learning, we present a novel attentive cross-modal connection to share information between convolutional neural networks responsible for learning individual modali…
IoT wearable devices are widely expected to reduce the cost and risk of personal healthcare. However, ambulatory data collected from such devices are often corrupted or contaminated with severe noises. Signal Quality Indicators (SQIs) can be used to assess the quality of data obtained from wearable devices, such that transmission/ storage of unusable data can be prevented. This article introduces a novel and generalized SQI which can be implemented on an edge device for detecting the quality of any quasi-periodic signal under observation, regardless of the type of noise present. The applicatio…
Ingenuity Labs Research Institute（Ingenuity Labs 研究院）
Electrocardiogram (ECG) is the electrical measurement of cardiac activity, whereas Photoplethysmogram (PPG) is the optical measurement of volumetric changes in blood circulation. While both signals are used for heart rate monitoring, from a medical perspective, ECG is more useful as it carries additional cardiac information. Despite many attempts toward incorporating ECG sensing in smartwatches or similar wearable devices for continuous and reliable cardiac monitoring, PPG sensors are the main feasible sensing solution available. In order to tackle this problem, we propose CardioGAN, an advers…
Monitoring of electrocardiogram (ECG) provides vital information as well as any cardiovascular anomalies. Recent advances in the technology of wearable electronics have enabled compact devices to acquire personal physiological signals in the home setting; however, signals are usually contaminated with high level noise. Thus, an efficient ECG filtering scheme is a dire need. In this paper, a novel method using Ensemble Kalman Filter (EnKF) is developed for denoising ECG signals. We also intensively explore various filtering algorithms, including Savitzky-Golay (SG) filter, Ensemble Empirical mo…
Real-time analysis and classification of bio-signals measured using wearable devices is computationally costly and requires dedicated low-power hardware. One promising approach is to use spiking neural networks implemented using in-memory computing architectures and neuromorphic electronic circuits. However, as these circuits process data in streaming mode without the possibility of storing it in external buffers, a major challenge lies in the processing of spatio-temporal signals that last longer than the time constants present in the network synapses and neurons. Here we propose to extend th…
Fifth-generation (5G) cellular networks promise higher data rates, lower latency, and large numbers of interconnected devices. Thereby, 5G will provide important steps towards unlocking the full potential of the Internet of Things (IoT). In this work, we propose a lightweight IoT platform for continuous vital sign analysis. Electrocardiography (ECG) is acquired via textile sensors and continuously sent from a smartphone to an edge device using cellular networks. The edge device applies a state-of-the art deep learning model for providing a binary end-to-end classification if a myocardial infar…
Continuous long-term monitoring of electrocardiography (ECG) signals is crucial for the early detection of cardiac abnormalities such as arrhythmia. Non-clinical ECG recordings acquired by Holter and wearable ECG sensors often suffer from severe artifacts such as baseline wander, signal cuts, motion artifacts, variations on QRS amplitude, noise, and other interferences. Usually, a set of such artifacts occur on the same ECG signal with varying severity and duration, and this makes an accurate diagnosis by machines or medical doctors extremely difficult. Despite numerous studies that have attem…
Multi-Channel Masked Autoencoder and Comprehensive Evaluations for Reconstructing 12-Lead ECG from Arbitrary Single-Lead ECG
National Institute of Health Data Science, Peking University（北京大学国家健康数据科学研究院）；School of Biomedical Engineering, Sun Yat-sen University（中山大学医学院生物医学工程学院）；Shanghai Jiao Tong University（上海交通大学）；Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University（天津医科大学第二附属医院天津心脏病学研究所）；Institute of Medical Technology, Health Science Center of Peking University（北京大学健康科学中心医学技术研究院）；Institute for Artificial Intelligence, Peking University（北京大学人工智能研究院）
Texas A&M University（得克萨斯农工大学）；Dell Inc.（戴尔公司）；Heart Artery and Vein Center of Fresno（弗雷斯诺心脏动脉与静脉中心）
Recent introduction of wearable single-lead ECG devices of diverse configurations has caught the intrigue of the medical community. While these devices provide a highly affordable support tool for the caregivers for continuous monitoring and to detect acute conditions, such as arrhythmia, their utility for cardiac diagnostics remains limited. This is because clinical diagnosis of many cardiac pathologies is rooted in gleaning patterns from synchronous 12-lead ECG. If synchronous 12-lead signals of clinical quality can be synthesized from these single-lead devices, it can transform cardiac care…
School of Electrical and Electronics Engineering（电气与电子工程学院）；University of Manchester（曼彻斯特大学）
Effective and powerful methods for denoising real electrocardiogram (ECG) signals are important for wearable sensors and devices. Deep Learning (DL) models have been used extensively in image processing and other domains with great success but only very recently have been used in processing ECG signals. This paper presents several DL models namely Convolutional Neural Networks (CNNs), Long Short-Term Memory (LSTM), Restricted Boltzmann Machine (RBM) together with the more conventional filtering methods (low pass filtering, high pass filtering, Notch filtering) and the standard wavelet-based te…
Philips Research North America（飞利浦北美研究院）；Advanced Algorithm Research Center, Philips Healthcare（飞利浦医疗先进算法研究中心）
The development of new technology such as wearables that record high-quality single channel ECG, provides an opportunity for ECG screening in a larger population, especially for atrial fibrillation screening. The main goal of this study is to develop an automatic classification algorithm for normal sinus rhythm (NSR), atrial fibrillation (AF), other rhythms (O), and noise from a single channel short ECG segment (9-60 seconds). For this purpose, signal quality index (SQI) along with dense convolutional neural networks was used. Two convolutional neural network (CNN) models (main model that acce…
ECGrecover: a Deep Learning Approach for Electrocardiogram Signal Completion
IRD（法国发展研究院）；Sorbonne Université（索邦大学）；University Paris-Saclay（巴黎-萨克雷大学）；INSERM（法国国家健康与医学研究院）；Pitié-Salpêtrière University Hospital（皮蒂-萨尔皮特里大学医院）；Vanderbilt University Medical Center（范德堡大学医学中心）；AP-HP（巴黎公共医疗集团）；Hôpital Pitié-Salpêtrière（皮蒂-萨尔皮特里医院）
Wireless body area networks (WBANs) are becoming increasingly popular as they allow individuals to continuously monitor their vitals and physiological parameters remotely from the hospital. With the spread of the SARS-CoV-2 pandemic, the availability of portable pulse-oximeters and wearable heart rate detectors has boomed in the market. At the same time, in 2020 we assisted to an unprecedented increase of healthcare breaches, revealing the extreme vulnerability of the current generation of WBANs. Therefore, the development of new security protocols to ensure data protection, authentication, in…
Electrocardiography (ECG), an electrical measurement which captures cardiac activities, is the gold standard for diagnosing cardiovascular disease (CVD). However, ECG is infeasible for continuous cardiac monitoring due to its requirement for user participation. By contrast, photoplethysmography (PPG) provides easy-to-collect data, but its limited accuracy constrains its clinical usage. To combine the advantages of both signals, recent studies incorporate various deep learning techniques for the reconstruction of PPG signals to ECG; however, the lack of contextual information as well as the lim…
Detection of Autonomic Dysreflexia in Individuals With Spinal Cord Injury Using Multimodal Wearable Sensors
SCAI-Lab, Department of Health Sciences and Technology (D-HEST), ETH Zurich（SCAI实验室，健康科学与技术系（D-HEST），苏黎世联邦理工学院）；School of Computation, Information and Technology, Technical University of Munich（计算、信息与技术学院，慕尼黑技术大学）；Swiss Paraplegic Research (SPF)（瑞士瘫痪研究机构（SPF））；Institute of Advanced Production Technologies, University of Valladolid（先进生产技术研究所，瓦尔达利德大学）；Swiss Paraplegic Centre (SPZ)（瑞士瘫痪中心（SPZ））；Balgrist University Hospital（巴尔格里斯大学医院）
