Cardiovascular disease has become one of the most significant threats endangering human life and health. Recently, Electrocardiogram (ECG) monitoring has been transformed into remote cardiac monitoring by Holter surveillance. However, the widely used Holter can bring a great deal of discomfort and inconvenience to the individuals who carry them. We developed a new wireless ECG patch in this work and applied a deep learning framework based on the Convolutional Neural Network (CNN) and Long Short-term Memory (LSTM) models. However, we find that the models using the existing techniques are not able to differentiate two main heartbeat types (Supraventricular premature beat and Atrial fibrillation) in our newly obtained dataset, resulting in low accuracy of 58.0 %. We proposed a semi-supervised method to process the badly labelled data samples with using the confidence-level-based training. The experiment results conclude that the proposed method can approach an average accuracy of 90.2 %, i.e., 5.4 % higher than the accuracy of conventional ECG classification methods.
Heartbeat classification using electrocardiogram (ECG) data is a vital assistive technology for wearable health solutions. We propose heartbeat feature classification based on a novel sparse representation using time-frequency joint distribution of ECG. Fundamental to this is a multi-layer perceptron, which incorporates these signatures to detect cardiac arrhythmia. This approach is validated with ECG data from MIT-BIH arrhythmia database. Results show that our approach has an average 95.7% accuracy, an improvement of 22% over state-of-the-art approaches. Additionally, ECG sparse distributed r…
HSE University（高等经济大学）；Sber AI Lab（俄联邦储蓄银行人工智能实验室）；Artificial Intelligence Research Institute (AIRI)（人工智能研究院（AIRI））
Cardiovascular disease remains a significant problem in modern society. Among non-invasive techniques, the electrocardiogram (ECG) is one of the most reliable methods for detecting abnormalities in cardiac activities. However, ECG interpretation requires expert knowledge and it is time-consuming. Developing a novel method to detect the disease early could prevent death and complication. The paper presents novel various approaches for classifying cardiac diseases from ECG recordings. The first approach suggests the Poincare representation of ECG signal and deep-learning-based image classifiers …
Personalized Deep Learning for Short-Term Forecasting of Impending Atrial Fibrillation from Continuous Wearable ECG Signals
Seoul National University（首尔大学）；CHA Bundang Medical Center and CHA University School of Medicine（CHA板桥医疗中心和CHA大学医学院）；SEERS Technology Co., Ltd（SEERS科技有限公司）；Department of Internal Medicine, Seoul National University College of Medicine and Seoul National University Hospital（首尔大学医学院内科学系和首尔大学医院）
Objective: A novel ECG classification algorithm is proposed for continuous cardiac monitoring on wearable devices with limited processing capacity. Methods: The proposed solution employs a novel architecture consisting of wavelet transform and multiple LSTM recurrent neural networks. Results: Experimental evaluations show superior ECG classification performance compared to previous works. Measurements on different hardware platforms show the proposed algorithm meets timing requirements for continuous and real-time execution on wearable devices. Conclusion: In contrast to many compute-intensive…
PPGFlowECG: Latent Rectified Flow with Cross-Modal Encoding for PPG-Guided ECG Generation and Cardiovascular Disease Detection
National Institute of Health Data Science, Peking University, China（北京大学国家健康数据科学研究院）；School of Intelligence Science and Technology, Peking University, China（北京大学智能科学与技术学院）；Data Science Institute, Imperial College London, UK（伦敦帝国理工学院数据科学研究院）；University of Chinese Academy of Sciences, China（中国科学院大学）
In this paper, we present a wireless ECG-derived Respiration Rate (RR) estimation using an autoencoder with a DCT Layer. The wireless wearable system records the ECG data of the subject and the respiration rate is determined from the variations in the baseline level of the ECG data. A straightforward Fourier analysis of the ECG data obtained using the wireless wearable system may lead to incorrect results due to uneven breathing. To improve the estimation precision, we propose a neural network that uses a novel Discrete Cosine Transform (DCT) layer to denoise and decorrelates the data. The DCT…
Electrocardiography (ECG), an electrical measurement which captures cardiac activities, is the gold standard for diagnosing cardiovascular disease (CVD). However, ECG is infeasible for continuous cardiac monitoring due to its requirement for user participation. By contrast, photoplethysmography (PPG) provides easy-to-collect data, but its limited accuracy constrains its clinical usage. To combine the advantages of both signals, recent studies incorporate various deep learning techniques for the reconstruction of PPG signals to ECG; however, the lack of contextual information as well as the lim…
Since cadiovascular disease (CVD) posts a heavy threat to people's health, long-term electrocardiogram (ECG) monitoring is of great value for the improvement of treatment. To realize remote long-term ECG monitoring, a low-power wireless wearable ECG monitoring device is proposed in this paper. The ECG monitoring device, abbreviated as ECGM, is designed based on ferroelectric microprocessor which provides ultra-low power consumption and contains four parts-MCU, BLE, Sensors and Power. The MCU part means circuit of MSP430FR2433, the core of ECGM. The BLE part is the CC2640R2F module applied for …
CarDS-Plus ECG Platform: Development and Feasibility Evaluation of a Multiplatform Artificial Intelligence Toolkit for Portable and Wearable Device Electrocardiograms
Yale School of Medicine（耶鲁医学院）；Yale New Haven Hospital（耶鲁-纽黑文医院）；Yale School of Public Health（耶鲁公共卫生学院）
Cardiac abnormalities affecting heart rate and rhythm are commonly observed in both healthy and acutely unwell people. Although many of these are benign, they can sometimes indicate a serious health risk. ECG monitors are typically used to detect these events in electrical heart activity, however they are impractical for continuous long-term use. In contrast, current-generation wearables with optical photoplethysmography (PPG) have gained popularity with their low-cost, lack of wires and tiny size. Many cardiac abnormalities such as ectopic beats and AF can manifest as both obvious and subtle …
This paper presents a novel ECG classification algorithm for real-time cardiac monitoring on ultra low-power wearable devices. The proposed solution is based on spiking neural networks which are the third generation of neural networks. In specific, we employ spike-timing dependent plasticity (STDP), and reward-modulated STDP (R-STDP), in which the model weights are trained according to the timings of spike signals, and reward or punishment signals. Experiments show that the proposed solution is suitable for real-time operation, achieves comparable accuracy with respect to previous methods, and…
National Institute of Health Data Science, Peking University（北京大学健康数据科学国家研究院）；Department of Cardiology, Peking University People’s Hospital（北京大学人民医院心内科）；Institute of Medical Technology, Peking University Health Science Center（北京大学医学部医学技术学院）；Tianjin Key Laboratory of lonic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University（天津医科大学第二医院心脏研究所心内科离子-分子心血管功能天津市重点实验室）
Electrocardiogram (ECG) is the most crucial monitoring modality to diagnose cardiovascular events. Precise and automatic detection of abnormal ECG patterns is beneficial to both physicians and patients. In the automatic detection of abnormal ECG patterns, deep neural networks (DNNs) have shown significant achievements. However, DNNs require large amount of labeled data, which are often expensive to obtain. On the other hand, recent research have shown by randomly combining data augmentations can improve image classification accuracy. Thus, in this work we explore data augmentation suitable for…
DUET（达卡工程技术大学）；EUB（欧洲孟加拉大学）；JNU（贾汉吉尔纳加尔大学）；Daffodil International University（达福迪尔国际大学）；BUP（孟加拉国国父和平大学）
Nearly 30% of the people in the rural areas of Bangladesh are below the poverty level. Moreover, due to the unavailability of modernized healthcare-related technology, nursing and diagnosis facilities are limited for rural people. Therefore, rural people are deprived of proper healthcare. In this perspective, modern technology can be facilitated to mitigate their health problems. ECG sensing tools are interfaced with the human chest, and requisite cardiovascular data is collected through an IoT device. These data are stored in the cloud incorporates with the MQTT and HTTP servers. An innovativ…
University College Dublin（都柏林大学学院）；National University of Singapore（新加坡国立大学）
Sudden cardiac death and arrhythmia account for a large percentage of all deaths worldwide. Electrocardiography (ECG) is the most widely used screening tool for cardiovascular diseases. Traditionally, ECG signals are classified manually, requiring experience and great skill, while being time-consuming and prone to error. Thus machine learning algorithms have been widely adopted because of their ability to perform complex data analysis. Features derived from the points of interest in ECG - mainly Q, R, and S, are widely used for arrhythmia detection. In this work, we demonstrate improved perfor…
Objectives: This study examines human Photoplethysmogram (PPG) along with Electrocardiogram (ECG) signals to study cardiac autonomic imbalance in epileptic seizures. The significance and the prevalence of changes in PPG morphological parameters have been investigated to find common patterns among subjects. Alterations in cardiovascular parameters measured by PPG/ECG signals are used to train a neural network based on LSTM for automatic seizure detection. Methods: Electroencephalogram (EEG), ECG, and PPG signals from 12 different subjects ( 8 males;4 females;age 34.3$\pm$ 13.8) were recorded in…
Ping An Technology（平安科技）；Saw Swee Hock School of Public Health, National University Health System, National University of Singapore（新加坡国立大学国立大学卫生系统苏瑞福公共卫生学院）；Yong Loo Lin School of Medicine, National University Health System, National University of Singapore（新加坡国立大学国立大学卫生系统杨潞龄医学院）；NUS Graduate School for Integrative Sciences & Engineering（新加坡国立大学综合科学与工程研究生院）；Institute of Data Science, National University of Singapore（新加坡国立大学数据科学研究所）
Cardiovascular disease is a major threat to health and one of the primary causes of death globally. The 12-lead ECG is a cheap and commonly accessible tool to identify cardiac abnormalities. Early and accurate diagnosis will allow early treatment and intervention to prevent severe complications of cardiovascular disease. In the PhysioNet/Computing in Cardiology Challenge 2020, our objective is to develop an algorithm that automatically identifies 27 ECG abnormalities from 12-lead ECG recordings.
The Chinese University of Hong Kong（香港中文大学）；Institute of Future Cities, The Chinese University of Hong Kong（香港中文大学未来城市研究所）；Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong（香港中文大学李嘉诚健康科学研究所）
Cardiovascular diseases (CVDs) are the number one cause of death worldwide. While there is growing evidence that the atrial fibrillation (AF) has strong associations with various CVDs, this heart arrhythmia is usually diagnosed using electrocardiography (ECG) which is a risk-free, non-intrusive, and cost-efficient tool. Continuously and remotely monitoring the subjects' ECG information unlocks the potentials of prompt pre-diagnosis and timely pre-treatment of AF before the development of any life-threatening conditions/diseases. Ultimately, the CVDs associated mortality could be reduced. In th…
Semi-Supervised Learning for Multi-Label Cardiovascular Diseases Prediction:A Multi-Dataset Study
City University of Hong Kong（香港城市大学）；Hong Kong Center for Cerebro-Cardiovascular Health Engineering（香港脑心血管健康工程中心）；University of Oxford（牛津大学）；Oxford-Suzhou Institute of Advanced Research（牛津苏州高等研究院）；Shenzhen University（深圳大学）；Micro sensing and imaging technologies limited（微传感与成像技术有限公司）；Wearable intelligent sensing technologies limited（可穿戴智能传感技术有限公司）
National Yang Ming Chiao Tung University（国立阳明交通大学）；Oklahoma State University（俄克拉荷马州立大学）
Arrhythmia detection from ECG is an important research subject in the prevention and diagnosis of cardiovascular diseases. The prevailing studies formulate arrhythmia detection from ECG as a time series classification problem. Meanwhile, early detection of arrhythmia presents a real-world demand for early prevention and diagnosis. In this paper, we address a problem of cardiovascular disease early classification, which is a varied-length and long-length time series early classification problem as well. For solving this problem, we propose a deep reinforcement learning-based framework, namely S…
University of Alberta（阿尔伯塔大学）；Canadian VIGOUR Centre（加拿大VIGOUR中心）；Alberta Machine Intelligence Institute（阿尔伯塔机器智能研究所）
Electrocardiogram (ECG) abnormalities are linked to cardiovascular diseases, but may also occur in other non-cardiovascular conditions such as mental, neurological, metabolic and infectious conditions. However, most of the recent success of deep learning (DL) based diagnostic predictions in selected patient cohorts have been limited to a small set of cardiac diseases. In this study, we use a population-based dataset of >250,000 patients with >1000 medical conditions and >2 million ECGs to identify a wide range of diseases that could be accurately diagnosed from the patient's first in-hospital …
University Medical Center Hamburg-Eppendorf (UKE)（汉堡-埃彭多夫大学医学中心（UKE））；Jacobs University gGmbH（雅各布大学gGmbH）
The reservoir computing paradigm is employed to classify heartbeat anomalies online based on electrocardiogram signals. Inspired by the principles of information processing in the brain, reservoir computing provides a framework to design, train, and analyze recurrent neural networks (RNNs) for processing time-dependent information. Due to its computational efficiency and the fact that training amounts to a simple linear regression, this supervised learning algorithm has been variously considered as a strategy to implement useful computations not only on digital computers but also on emerging u…
According to the World Health Organization, around 36% of the annual deaths are associated with cardiovascular diseases and 90% of heart attacks are preventable. Electrocardiogram signal analysis in ambulatory electrocardiography, during an exercise stress test, and in resting conditions allows cardiovascular disease diagnosis. However, during the acquisition, there is a variety of noises that may damage the signal quality thereby compromising their diagnostic potential. The baseline wander is one of the most undesirable noises. In this work, we propose a novel algorithm for BLW noise filterin…
AnyPPG: An ECG-Guided PPG Foundation Model Trained on Over 100,000 Hours of Recordings for Holistic Health Profiling
School of Intelligence Science and Technology, Peking University（北京大学智能科学与技术学院）；State Key Laboratory of General Artificial Intelligence, Peking University（北京大学通用人工智能全国重点实验室）；National Institute of Health Data Science, Peking University（北京大学健康医疗大数据国家研究院）
University of North Carolina（北卡罗来纳大学）；George Washington University（乔治·华盛顿大学）
Breathing rate (BR), minute ventilation (VE), and other respiratory parameters are essential for real-time patient monitoring in many acute health conditions, such as asthma. The clinical standard for measuring respiration, namely Spirometry, is hardly suitable for continuous use. Wearables can track many physiological signals, like ECG and motion, yet not respiration. Deriving respiration from other modalities has become an area of active research. In this work, we infer respiratory parameters from wearable ECG and wrist motion signals. We propose a modular and generalizable classification-re…
Stanford Online High School（斯坦福在线高中）；AliveCor, Inc.（AliveCor公司）
Mobile electrocardiogram (ECG) recording technologies represent a promising tool to fight the ongoing epidemic of cardiovascular diseases, which are responsible for more deaths globally than any other cause. While the ability to monitor one's heart activity at any time in any place is a crucial advantage of such technologies, it is also the cause of a drawback: signal noise due to environmental factors can render the ECGs illegible. In this work, we develop convolutional neural networks (CNNs) to automatically label ECGs for noise, training them on a novel noise-annotated dataset. By reducing …
A Nonlinear Complexity Index for Wearable PPG Cardiovascular Stability: Multiscale Validation, Systematic Evaluation Correction, and Bayesian Parameter Optimization
Department of Computer Science, Morgan State University（莫根州立大学计算机科学系）
Cardiovascular diseases are the leading cause of death worldwide, accounting for 17.3 million deaths per year. The electrocardiogram (ECG) is a non-invasive technique widely used for the detection of cardiac diseases. To increase diagnostic sensitivity, ECG is acquired during exercise stress tests or in an ambulatory way. Under these acquisition conditions, the ECG is strongly affected by some types of noise, mainly by baseline wander (BLW). In this work were implemented nine methods widely used for the elimination of BLW, which are: interpolation using cubic splines, FIR filter, IIR filter, l…
The electrocardiogram (ECG) has always been an important biomedical test to diagnose cardiovascular diseases. Current approaches for ECG monitoring are based on body attached electrodes leading to uncomfortable user experience. Therefore, contactless ECG monitoring has drawn tremendous attention, which however remains unsolved. In fact, cardiac electrical-mechanical activities are coupling in a well-coordinated pattern. In this paper, we achieve contactless ECG monitoring by breaking the boundary between the cardiac mechanical and electrical activity. Specifically, we develop a millimeter-wave…
IoT wearable devices are widely expected to reduce the cost and risk of personal healthcare. However, ambulatory data collected from such devices are often corrupted or contaminated with severe noises. Signal Quality Indicators (SQIs) can be used to assess the quality of data obtained from wearable devices, such that transmission/ storage of unusable data can be prevented. This article introduces a novel and generalized SQI which can be implemented on an edge device for detecting the quality of any quasi-periodic signal under observation, regardless of the type of noise present. The applicatio…
Objective: Continuous monitoring of biosignals via wearable sensors has quickly expanded in the medical and wellness fields. At rest, automatic detection of vital parameters is generally accurate. However, in conditions such as high-intensity exercise, sudden physiological changes occur to the signals, compromising the robustness of standard algorithms. Methods: Our method, called BayeSlope, is based on unsupervised learning, Bayesian filtering, and non-linear normalization to enhance and correctly detect the R peaks according to their expected positions in the ECG. Furthermore, as BayeSlope i…
The recent developments in wearable devices and the Internet of Medical Things (IoMT) allow real-time monitoring and recording of electrocardiogram (ECG) signals. However, continuous monitoring of ECG signals is challenging in low-power wearable devices due to energy and memory constraints. Therefore, in this paper, we present a novel and energy-efficient methodology for continuously monitoring the heart for low-power wearable devices. The proposed methodology is composed of three different layers: 1) a Noise/Artifact detection layer to grade the quality of the ECG signals; 2) a Normal/Abnorma…
