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arXiv 1507.01236math.AP
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一类具有内动力学的趋化性动力学模型的整体解及其快速适应极限

Global solution for a kinetic chemotaxis model with internal dynamics and its fast adaptation limit

Jie Liao

摘要:

考虑了一个包含信号转导和适应的非线性动力学趋化模型。本文讨论了:(i)该模型的整体解,(ii)它对Othmer-Dunbar-Alt型模型的快速适应极限。这一限制提供了一些见解的分子起源的趋化性行为。首先利用Schauder不动点定理,在对模型和初值作了一般性假设的情况下,基于详细的先验估计,证明了该模型弱解的整体存在性.然而,Schauder不动点定理不提供唯一性。因此,需要进行额外的分析以获得唯一性。其次,通过在测度空间中提取弱收敛子序列,得到了该模型的快速自适应极限。对于这个极限,第一个困难是要表明浓度对内部状态的影响。当小参数ε,适应时间尺度,趋于零,我们证明了解决方案收敛到一个狄拉克质量的内部状态变量。另一个困难是关于化学势的强紧性论证,这是将非线性动力学方程传递到弱极限的必要条件。

英文摘要:

A nonlinear kinetic chemotaxis model with internal dynamics incorporating signal transduction and adaptation is considered. This paper is concerned with: (i) the global solution for this model, and, (ii) its fast adaptation limit to Othmer-Dunbar-Alt type model. This limit gives some insight to the molecular origin of the chemotaxis behaviour. First, by using the Schauder fixed point theorem, the global existence of weak solution is proved based on detailed a priori estimates, under some quite general assumptions on the model and the initial data. However, the Schauder fixed point theorem does not provide uniqueness. Therefore, additional analysis is required to be developed to obtain uniqueness. Next, the fast adaptation limit of this model is derived by extracting a weak convergence subsequence in measure space. For this limit, the first difficulty is to show the concentration effect on the internal state. When the small parameter ε, the adaptation time scale, goes to zero, we prove that the solution converges to a Dirac mass in the internal state variable. Another difficulty is the strong compactness argument on the chemical potential, which is essential for passing the nonlinear kinetic equation to the weak limit.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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