Development of liquid xenon detectors for medical imaging
V. Chepel, M. I. Lopes, V. Solovov, R. Ferreira Marques, A. J. P. L. Policarpo
备注：
13 pages, 5 figures, presented on the International Workshop on Techniques and Applications of Xenon Detectors (Xenon01), ICRR, Univ. of Tokyo, Kashiwa, Japan, December 3-4, 2001 (submitted to proceedings)
In the present paper, we report on our developments of liquid xenon detectors for medical imaging, positron emission tomography and single photon imaging, in particular. The results of the studies of several photon detectors (photomultiplier tubes and large area avalanche photodiode) suitable for detection of xenon scintillation are also briefly described.
The fast scintillation decay time and the high scintillation yield of liquid xenon makes it an appropriate material for nuclear medicine. Moreover, being a continuous medium with a uniform response, liquid xenon allows one to avoid most of the geometrical distortions of conventional detectors based on scintillating crystals. In this paper, we describe how these properties have motivated the development of a novel concept for positron emission tomography scanners with Time-Of-Flight measurement, which uses liquid xenon as a scintillating material and silicon photomultipliers as sensors. Monte C…
New detector approaches in Positron Emission Tomography imaging will play an important role in reducing costs, lowering administered radiation doses, and improving overall performance. PETALO employs liquid xenon as the active scintillating medium and UV-sensitive silicon photomultipliers for scintillation readout. The scintillation time in liquid xenon is fast enough to register time-of-flight information for each detected coincidence, and sufficient scintillation is produced with low enough fluctuations to obtain good energy resolution. The present simulation study examines a full-body-sized…
As liquid xenon detectors grow in scale, novel techniques are required to maintain sufficient purity for charges to survive across longer drifts. The Xeclipse test facility at Columbia University was built to test the removal of electronegative impurities through cryogenic filtration powered by a liquid xenon pump, enabling a far higher mass flow rate than gas-phase purification through heated getters. In this paper, we present results from Xeclipse, including measured oxygen removal rates for two sorbent materials, which were used to guide the design and commissioning of the XENONnT liquid pu…
Liquid xenon has several attractive features, which make it suitable for applications to nuclear medicine, such as high scintillation yield and fast scintillation decay time, better than currently used crystals. Since the '90s, several attempts has been made to build Positron Emission Tomography scanners based on liquid xenon, which can be divided into two different approaches: on one hand, the detection of the ionization charge in TPCs, and, on the other one, the detection of scintillation light with photomultipliers. PETALO (Positron Emission Tof Apparatus with Liquid xenOn) is a novel conce…
Liquid xenon particle detectors rely on excellent light collection efficiency for their performance. This depends on the high reflectivity of polytetrafluoroethylene (PTFE) at the xenon scintillation wavelength of 178 nm, but the angular dependence of this reflectivity is not well-understood. IBEX is designed to directly measure the angular distribution of xenon scintillation light reflected off PTFE in liquid xenon. These measurements are fully described by a microphysical reflectivity model with few free parameters. Dependence on PTFE type, surface finish, xenon pressure, and wavelength of i…
Liquid argon detectors are employed in a wide variety of nuclear and particle physics experiments. The addition of small quantities of xenon to argon modifies its scintillation, ionization, and electroluminescence properties and can improve its performance as a detection medium. However, a liquid argon-xenon mixture can develop instabilities, especially in systems that require phase transitions or that utilize high xenon concentrations. In this work, we discuss the causes for such instabilities and describe a small (liter-scale) apparatus with a unique cryogenic circuit specifically designed t…
As noble liquid time projection chambers grow in size their high voltage requirements increase, and detailed, reproducible studies of dielectric breakdown and the onset of electroluminescence are needed to inform their design. The Xenon Breakdown Apparatus (XeBrA) is a 5-liter cryogenic chamber built to characterize the DC high voltage breakdown behavior of liquid xenon and liquid argon. Electrodes with areas up to 33~cm$^2$ were tested while varying the cathode-anode separation from 1 to 6~mm with a voltage difference up to 75~kV. A power-law relationship between breakdown field and electrode…
Liquid Xenon Detectors for Particle Physics and Astrophysics
本文综述了近20年来液体氙探测器的发展及其在粒子物理、天体物理和医学成像实验中的应用。我们首先总结了液体氙作为辐射探测介质的基本性质，根据最新的理论和实验信息。在简要介绍了不同类型的液体氙探测器后，我们继续回顾了过去，现在和未来的实验，使用液体氙寻找罕见的过程和图像辐射在空间和医学。我们将介绍每个应用程序的基本科学动机和实验要求的简要调查，然后审查每个实验的基本特征和预期性能。在这十年内，以不同模式运行的大容量液体氙探测器似乎将有助于回答粒子物理学，天体物理学和宇宙学中一些最基本的问题，满足最苛刻的探测挑战。从MEG这样的实验，目前运行中最大的液体氙闪烁探测器，致力于罕见的mu -> e +伽马衰变，到未来的XMASS，它也只利用液体氙闪烁来解决罕见事件搜索的雄心勃勃的计划，到时间投影室的类别，如XENON和EXO，它们利用液体氙的闪烁和电离来获得暗物质和无中微子双β衰变，分别，我们预计在未来几年无可匹敌的性能和重要贡献的物理学。
First imaging results in liquid xenon of a Liquid Hole Multiplier (LHM) coupled to a Quad-Silicon Photomultiplier (SiPM) array are presented. Ionization electrons deposited in the noble liquid by 5.5 MeV alpha particles, are collected into the holes of a Thick Gas Electron Multiplier (THGEM) electrode having a xenon gas bubble trapped underneath. They drift through the liquid-gas interface, inducing electroluminescence within the bubble. The resulting photons are detected with a Hamamatsu VUV4 quad-SiPM array - providing the deposited energy with a charge-only RMS resolution of 6.6%. The image…
The use of xenon-doped liquid argon is a promising alternative for large pure liquid-argon TPCs. Not only xenon-doped liquid argon enhances the light production, mitigating the possible suppression due to impurities, but also it increases the wavelength of the scintillation light, enlarging the effective Rayleigh scattering length and improving the detection uniformity. ProtoDUNE Dual-Phase is a 300-ton active volume LAr TPC, a prototype for the Deep Underground Neutrino Experiment (DUNE), a dual-site experiment for long-baseline neutrino oscillation studies, neutrino astrophysics and nucleon …
The feasibility of an ultra-low energy nuclear-recoil measurement in liquid xenon using neutron capture is investigated for a small (sub-kilogram) liquid xenon detector that is optimized for a high scintillation gain, and a pulsed neutron source. The measurement uses the recoil energies imparted to xenon nuclei during the de-excitation process following neutron capture, where promptly emitted $γ$ cascades can provide the nuclei with up to $0.3$ keV$_\text{nr}$ of recoil energy due to conservation of momentum. A successful calibration of scintillation photon and ionization electron yields below…
Neutrinoless double beta decays in liquid xenon produce a significant amount of Cherenkov light, with a photon number and angular distribution that distinguishes these events from common backgrounds. A GEANT4 simulation was used to simulate Cherenkov photon production and measurement in a liquid xenon detector and a multilayer perceptron was used to analyze the resulting distributions to classify events based on their Cherenkov photons. Our results show that a modest improvement in the sensitivity of neutrinoless double beta decay searches is possible using this technique, but the kinematics o…
PETALO (Positron Emission Tof Apparatus with Liquid xenOn) is a novel concept for positron emission tomography scanners, which uses liquid xenon as a scintillation medium and silicon photomultipliers as a readout. The large scintillation yield and the fast scintillation time of liquid xenon, as well as its scalability, makes it an excellent candidate for PET scanners with Time-of-Flight measurements, especially for total-body machines. A first prototype of PETALO is fully operating, devoted to demonstrate the potential of the concept, measuring the energy and time resolution and to test techni…
Attenuation of vacuum ultraviolet light in pure and xenon-doped liquid argon - an approach to an assignment of the near-infrared emission from the mixture
Xenon-doped liquid argon has been proposed as a good alternative to pure liquid argon in scintillation detectors. In this study, we report on the measurement of the time profile of scintillation light emitted from xenon-doped liquid argon with molar concentrations up to 1600 ppm. A compact setup has been developed for this study, with silicon photomultiplier (SiPM) as the photosensor and $^{210}\mathrm{Po}$ and $^{90}\mathrm{Sr}$ as scintillation sources. An effective model based on the de-excitation processes has been developed to describe the data. The results show that xenon-doped liquid ar…
We have measured the properties of scintillation light in liquid argon doped with xenon concentrations from 165 ppm to 10,010 ppm using a $^{22}$Na source. The energy transfer processes in the xenon-doped liquid argon are discussed in detail, and a new waveform model is established and used to fit the average waveform. The time profile of the scintillation photon in the xenon-doped liquid argon and of the TPB emission are presented. The quantities of xenon-doped are controlled by a Mass Flow Controller which is calibrated via a Redusial Gas Analyzer to ensure that the xenon concentration is ac…
The detection of scintillation light from liquid argon is an experimental technique key to a number of current and future nuclear/particle physics experiments, such as neutrino physics, neutrinoless double beta decay and dark matter searches. Although the idea of adding small quantities of xenon (doping) to enhance the light yield has attracted considerable interest, this technique has never been demonstrated at the necessary scale or precision. Here we report on xenon doping in a 100 l cryogenic vessel. Xenon doping was performed in four concentrations of 1.00$\pm$0.06 ppm, 2.0$\pm$0.1 ppm, 5…
We report a demonstration of the scalability of optically transparent xenon in the solid phase for use as a particle detector above a kilogram scale. We employ a liquid nitrogen cooled cryostat combined with a xenon purification and chiller system to measure the scintillation light output and electron drift speed from both the solid and liquid phases of xenon. Scintillation light output from sealed radioactive sources is measured by a set of high quantum efficiency photomultiplier tubes suitable for cryogenic applications. We observed a reduced amount of photons in solid phase compared to that…
Monte Carlo simulations are a crucial tool for the analysis and prediction of various background components in liquid xenon (LXe) detectors. With improving shielding in new experiments, the simulation of external backgrounds, such as induced by gamma rays from detector materials, gets more computationally expensive. We introduce and validate an accelerated Monte Carlo simulation technique for photon transport in liquid xenon detectors. The method simulates photon-induced interactions within a defined geometry and energy range with high statistics while interactions outside of the region of int…
Polytetrafluoroethylene (PTFE), also known as Teflon, is a common material used in the construction of liquid xenon detectors due to its high reflectivity for the VUV scintillation light of xenon. We present transmission measurements of PTFE for xenon scintillation light with peak emission at a wavelength of 175 nm. PTFE discs of different thicknesses are installed in front of a photosensor in two setups. One is filled with gaseous xenon, the other with liquid xenon. The measurements performed with the gaseous xenon setup at room temperature yield a transmission coefficient of $λ= \bigl(350{{}…
Liquid xenon offers several features, which make it suitable for applications in nuclear medicine, such as high scintillation yield and fast scintillation decay time. Moreover, being a continuous medium with a uniform response, liquid xenon allows one to avoid most of the geometrical distortions of conventional detectors based on scintillating crystals. In this paper, we describe how these properties have motivated the development of a novel concept for positron emission tomography scanners with Time-Of-Flight measurement, which combines a liquid xenon scintillating volume and silicon photomul…
The radioactive daughters isotope of 222Rn are one of the highest risk contaminants in liquid xenon detectors aiming for a small signal rate. The noble gas is permanently emanated from the detector surfaces and mixed with the xenon target. Because of its long half-life 222Rn is homogeneously distributed in the target and its subsequent decays can mimic signal events. Since no shielding is possible this background source can be the dominant one in future large scale experiments. This article provides an overview of strategies used to mitigate this source of background by means of material selec…
Understanding liquid xenon scintillation and ionization processes is of great interest to improve analysis methods in current and future detectors. In this paper, we investigate the dynamics of the scintillation process for excitation by $\mathcal{O}$(10 keV) electrons from a $^{83m}$Kr source and $\mathcal{O}$(6 MeV) $α$-particles from a $^{222}$Rn source, both mixed with the xenon target. The single photon sampling method is used to record photon arrival times in order to obtain the corresponding time distributions for different applied electric fields between about 0.8 V/cm to 1.2 kV/cm. En…
Liquid xenon based detectors have achieved great sensitivities in rare event searches. Precise knowledge of the scintillation and ionization responses of the medium is essential to correctly model different interaction types in the detector including both signal and background-like ones. The response of liquid xenon to low energy electrons and to alpha particles has been studied in the Heidelberg Xenon (HeXe) dual-phase xenon TPC. We determine the light and charge signal yields for keV-energy electrons and MeV-energy alpha particles as well as the electron drift velocity for electric drift fie…
The liquid xenon (LXe) time projection chamber (TPC) technology is probing a wide range of dark matter masses from sub-GeV to a few TeV. To further improve its sensitivity to sub-GeV dark matter and its application in reactor neutrino monitoring via coherent elastic neutrino-nucleus scattering (CEvNS), more understanding and suppression of single/few electrons background rate are needed. Here we report on the design and performance of a sealed LXeTPC with a graphene-coated fused silica window as the cathode. The purpose of the sealed TPC is for isolating the liquid xenon target volume from the…
We report the first precision measurement of the superheat temperature required for bubble nucleation in liquid xenon of $ΔT_{wall,ONB}$ = (16.9$\pm$0.5) K and $ΔT_{wall,ONB}$ = (19.2$^{+0.4}_{-1.1}$) K at pressures of P = $(0.98\pm0.02)$ bar and P = $(1.32^{+0.05}_{-0.01})$ bar, respectively. Both are measured at a subcooled bulk fluid temperature of $\sim$ 162 K. A dedicated liquid xenon setup is used to measure the temperature at which bubble nucleation first appears on the flat surface of a resistor. The associated average heat flux at the surface of the resistor is determined using fluid …
XeBRA is a flexible cryogenic platform designed to perform research and development for liquid xenon detectors searching for rare events. Its extra-large outer cryostat makes it possible to install a wide variety of detector designs. We present the system, including its cryogenic, gas handling, data acquisition and slow control subsystems. Two dual phase time projection chambers with sensitive masses at the 1 kg scale have so far been operated in XeBRA. Using data from these, we determine the field-dependence of the electron drift velocity in liquid xenon. We also measure the relative charge a…
