An important and yet difficult problem in fitting multivariate mixture models is determining the mixture complexity. We develop theory and a unified framework for finding the nonparametric maximum likelihood estimator of a multivariate mixing distribution and consequently estimating the mixture complexity. Multivariate mixtures provide a flexible approach to fitting high-dimensional data while offering data reduction through the number, location and shape of the component densities. The central principle of our method is to cast the mixture maximization problem in the concave optimization framework with finitely many linear inequality constraints and turn it into an unconstrained problem using a "penalty function". We establish the existence of parameter estimators and prove the convergence properties of the proposed algorithms. The role of a "sieve parameter'' in reducing the dimensionality of mixture models is demonstrated. We derive analytical machinery for building a collection of semiparametric mixture models, including the multivariate case, via the sieve parameter. The performance of the methods are shown with applications to several data sets including the cdc15 cell-cycle yeast microarray data.
In this paper we propose a generalization of a class of Gaussian Semiparametric Estimators (GSE) of the fractional differencing parameter for long-range dependent multivariate time series. We generalize a known GSE-type estimator by introducing some modifications at the objective function level regarding the process' spectral density matrix estimator. We study large sample properties of the estimator without assuming Gaussianity as well as hypothesis testing. The class of models considered here satisfies simple conditions on the spectral density function, restricted to a small neighborhood of …
There is a difficulty in finding an estimate of variance of the profile likelihood estimator in the joint model of longitudinal and survival data. We solve the difficulty by introducing the ``statistical generalized derivative''. The derivative is used to show the asymptotic normality of the estimator without assuming the second derivative of the density function in the model exists.
In this paper, we consider nonparametric multidimensional finite mixture models and we are interested in the semiparametric estimation of the population weights. Here, the i.i.d. observations are assumed to have at least three components which are independent given the population. We approximate the semiparametric model by projecting the conditional distributions on step functions associated to some partition. Our first main result is that if we refine the partition slowly enough, the associated sequence of maximum likelihood estimators of the weights is asymptotically efficient, and the poste…
Suppose that univariate data are drawn from a mixture of two distributions that are equal up to a shift parameter. Such a model is known to be nonidentifiable from a nonparametric viewpoint. However, if we assume that the unknown mixed distribution is symmetric, we obtain the identifiability of this model, which is then defined by four unknown parameters: the mixing proportion, two location parameters and the cumulative distribution function of the symmetric mixed distribution. We propose estimators for these four parameters when no training data is available. Our estimators are shown to be st…
We consider X 1 ,. .. , X n a sample of data on the circle S 1 , whose distribution is a twocomponent mixture. Denoting R and Q two rotations on S 1 , the density of the X i 's is assumed to be g(x) = pf (R --1 x) + (1 -- p)f (Q --1 x), where p $\in$ (0, 1) and f is an unknown density on the circle. In this paper we estimate both the parametric part $θ$ = (p, R, Q) and the nonparametric part f. The specific problems of identifiability on the circle are studied. A consistent estimator of $θ$ is introduced and its asymptotic normality is proved. We propose a Fourier-based estimator of f with a p…
In this paper we study the problem of statistical inference on the parameters of the semiparametric variance-mean mixtures. This class of mixtures has recently become rather popular in statistical and financial modelling. We design a semiparametric estimation procedure that first estimates the mean of the underlying normal distribution and then recovers nonparametrically the density of the corresponding mixing distribution. We illustrate the performance of our procedure on simulated and real data.
In this article, we revisit the problem of fitting a mixture model under the assumption that the mixture components are symmetric and log-concave. To this end, we first study the nonparametric maximum likelihood estimation (NPMLE) of a monotone log-concave probability density. By following the arguments of Rufibach (2006), we show that the NPMLE is uniformly consistent with respect to the supremum norm on compact subsets of the interior of the support. To fit the mixture model, we propose a semiparametric EM (SEM) algorithm, which can be adapted to other semiparametric mixture models. In our n…
We propose a new class of R-estimators for semiparametric VARMA models in which the innovation density plays the role of the nuisance parameter. Our estimators are based on the novel concepts of multivariate center-outward ranks and signs. We show that these concepts, combined with Le Cam's asymptotic theory of statistical experiments, yield a class of semiparametric estimation procedures, which are efficient (at a given reference density), root-$n$ consistent, and asymptotically normal under a broad class of (possibly non elliptical) actual innovation densities. No kernel density estimation i…
The prevalence of spatially referenced multivariate data has impelled researchers to develop a procedure for the joint modeling of multiple spatial processes. This ordinarily involves modeling marginal and cross-process dependence for any arbitrary pair of locations using a multivariate spatial covariance function. However, building a flexible multivariate spatial covariance function that is nonnegative definite is challenging. Here, we propose a semiparametric approach for multivariate spatial covariance function estimation with approximate Matérn marginals and highly flexible cross-covarianc…
We propose a semiparametric mixture model to estimate local false discovery rates in multiple testing problems. The two pilars of the proposed approach are Efron's empirical null principle and log-concave density estimation for the alternative distribution. Compared to existing methods, our method can be easily extended to high dimension. Simulation results show that our method outperforms other existing methods and we illustrate its use via case studies in astronomy and microarray.
Motivated by studies in biological sciences to detect differentially expressed genes, a semiparametric two-component mixture model with one known component is being studied in this paper. Assuming the density of the unknown component to be log-concave, which contains a very broad family of densities, we develop a semiparametric maximum likelihood estimator and propose an EM algorithm to compute it. Our new estimation method finds the mixing proportions and the distribution of the unknown component simultaneously. We establish the identifiability of the proposed semiparametric mixture model and…
In this paper, we propose finite mixtures of multivariate skew Laplace distributions to model both skewness and heavy-tailedness in the heterogeneous data sets. The maximum likelihood estimators for the parameters of interest are obtained by using the EM algorithm. We give a small simulation study and a real data example to illustrate the performance of the proposed mixture model.
In this article, we propose a penalized high dimensional semiparametric model average quantile prediction approach that is robust for forecasting the conditional quantile of the response. We consider a two-step estimation procedure. In the first step, we use a local linear regression approach to estimate the individual marginal quantile functions, and approximate the conditional quantile of the response by an affine combination of one-dimensional marginal quantile regression functions. In the second step, based on the nonparametric kernel estimates of the marginal quantile regression functions…
In fitting a mixture of linear regression models, normal assumption is traditionally used to model the error and then regression parameters are estimated by the maximum likelihood estimators (MLE). This procedure is not valid if the normal assumption is violated. To relax the normal assumption on the error distribution hence reduce the modeling bias, we propose semiparametric mixture of linear regression models with unspecified error distributions. We establish a more general identifiability result under weaker conditions than existing results, construct a class of new estimators, and establis…
In this paper, we propose new semiparametric procedures for making inference on linear functionals and their functions of two semicontinuous populations. The distribution of each population is usually characterized by a mixture of a discrete point mass at zero and a continuous skewed positive component, and hence such distribution is semicontinuous in the nature. To utilize the information from both populations, we model the positive components of the two mixture distributions via a semiparametric density ratio model. Under this model setup, we construct the maximum empirical likelihood estima…
When facing multivariate covariates, general semiparametric regression techniques come at hand to propose flexible models that are unexposed to the curse of dimensionality. In this work a semiparametric copula-based estimator for conditional quantiles is investigated for complete or right-censored data. In spirit, the methodology is extending the recent work of Noh et al. (2013) and Noh et al. (2015), as the main idea consists in appropriately defining the quantile regression in terms of a multivariate copula and marginal distributions. Prior estimation of the latter and simple plug-in lead to…
We consider a common-components model for multivariate fractional cointegration, in which the $s\geq1$ components have different memory parameters. The cointegrating rank may exceed 1. We decompose the true cointegrating vectors into orthogonal fractional cointegrating subspaces such that vectors from distinct subspaces yield cointegrating errors with distinct memory parameters. We estimate each cointegrating subspace separately, using appropriate sets of eigenvectors of an averaged periodogram matrix of tapered, differenced observations, based on the first $m$ Fourier frequencies, with $m$ fi…
Semiparametric estimation for multivariate Hawkes processes using dependent Dirichlet processes: An application to order flow data in financial markets
The paper concerns the asymptotic distribution of the mixture density estimator, proposed by Oppenheim et al 2006, in the aggregation/disaggregation problem of random parameter AR(1) process. We prove that, under mild conditions on the (semiparametric) form of the mixture density, the estimator is asymptotically normal. The proof is based on the limit theory for the quadratic form in linear random variables developed by Bhansali et al 2007. The moving average representation of the aggregated process is investigated. A small simulation study illustrates the result.
A challenge when dealing with survival analysis data is accounting for a cure fraction, meaning that some subjects will never experience the event of interest. Mixture cure models have been frequently used to estimate both the probability of being cured and the time to event for the susceptible subjects, by usually assuming a parametric (logistic) form of the incidence. We propose a new estimation procedure for a parametric cure rate that relies on a preliminary smooth estimator and is independent of the model assumed for the latency. We investigate the theoretical properties of the estimators…
Multivariate processes with long-range dependent properties are found in a large number of applications including finance, geophysics and neuroscience. For real data applications, the correlation between time series is crucial. Usual estimations of correlation can be highly biased due to phase-shifts caused by the differences in the properties of autocorrelation in the processes. To address this issue, we introduce a semiparametric estimation of multivariate long-range dependent processes. The parameters of interest in the model are the vector of the long-range dependence parameters and the lo…
This paper deals with a situation when one is interested in the dependence structure of a multidimensional response variable in the presence of a multivariate covariate. It is assumed that the covariate affects only the marginal distributions through regression models while the dependence structure, which is described by a copula, is unaffected. A parametric estimation of the copula function is considered with focus on the maximum pseudo-likelihood method. It is proved that under some appropriate regularity assumptions the estimator calculated from the residuals is asymptotically equivalent to…
A class of R-estimators based on the concepts of multivariate signed ranks and the optimal rank-based tests developed in Hallin and Paindaveine [Ann. Statist. 34 (2006)] is proposed for the estimation of the shape matrix of an elliptical distribution. These R-estimators are root-n consistent under any radial density g, without any moment assumptions, and semiparametrically efficient at some prespecified density f. When based on normal scores, they are uniformly more efficient than the traditional normal-theory estimator based on empirical covariance matrices (the asymptotic normality of which,…
Robust and semiparametric statistics are of the same historical origin and largely employ the same locally asymptotically normal framework. In our talk, we consider he following more intrinsic connections of both fields: 1) Robust influence curves for semiparametric models with infinite dimensional nuisance parameter; for example, for semiparametric regression (Cox), and mixture models (Neyman--Scott). 2) Adaptiveness in the sense of Stein's necessary condition of robust neighborhood models and estimators with respect to a finite dimensional nuisance parameter; for example, location, linear re…
We develop a class of tests for semiparametric vector autoregressive (VAR) models with unspecified innovation densities, based on the recent measure-transportation-based concepts of multivariate {\it center-outward ranks} and {\it signs}. We show that these concepts, combined with Le Cam's asymptotic theory of statistical experiments, yield novel testing procedures, which (a)~are valid under a broad class of innovation densities (possibly non-elliptical, skewed, and/or with infinite moments), (b)~are optimal (locally asymptotically maximin or most stringent) at selected ones, and (c) are robus…
A model-assisted semiparametric method of estimating finite population totals is investigated to improve the precision of survey estimators by incorporating multivariate auxiliary information. The proposed superpopulation model is a single-index model which has proven to be a simple and efficient semiparametric tool in multivariate regression. A class of estimators based on polynomial spline regression is proposed. These estimators are robust against deviation from single-index models. Under standard design conditions, the proposed estimators are asymptotically design-unbiased, consistent and …
Cure models have been developed as an alternative modelling approach to conventional survival analysis in order to account for the presence of cured subjects that will never experience the event of interest. Mixture cure models, which model separately the cure probability and the survival of uncured subjects depending on a set of covariates, are particularly useful for distinguishing curative from life-prolonging effects. In practice, it is common to assume a parametric model for the cure probability and a semiparametric model for the survival of the susceptibles. Because of the latent cure st…
In this paper, a new mixture family of multivariate normal distributions, formed by mixing multivariate normal distribution and skewed distribution, is constructed. Some properties of this family, such as characteristic function, moment generating function, and the first four moments are derived. The distributions of affine transformations and canonical forms of the model are also derived. An EM type algorithm is developed for the maximum likelihood estimation of model parameters. We have considered in detail, some special cases of the family, using standard gamma and standard exponential mixt…
The Gini index is a popular inequality measure with many applications in social and economic studies. This paper studies semiparametric inference on the Gini indices of two semicontinuous populations. We characterize the distribution of each semicontinuous population by a mixture of a discrete point mass at zero and a continuous skewed positive component. A semiparametric density ratio model is then employed to link the positive components of the two distributions. We propose the maximum empirical likelihood estimators of the two Gini indices and their difference, and further investigate the a…
Multivariate normal mixtures provide a flexible model for high-dimensional data. They are widely used in statistical genetics, statistical finance, and other disciplines. Due to the unboundedness of the likelihood function, classical likelihood-based methods, which may have nice practical properties, are inconsistent. In this paper, we recommend a penalized likelihood method for estimating the mixing distribution. We show that the maximum penalized likelihood estimator is strongly consistent when the number of components has a known upper bound. We also explore a convenient EM-algorithm for co…
A new estimation method for the two-component mixture model introduced in \cite{Van13} is proposed. This model consists of a two-component mixture of linear regressions in which one component is entirely known while the proportion, the slope, the intercept and the error distribution of the other component are unknown. In spite of good performance for datasets of reasonable size, the method proposed in \cite{Van13} suffers from a serious drawback when the sample size becomes large as it is based on the optimization of a contrast function whose pointwise computation requires O(n^2) operations. T…
Non-ignorable dropout is common in studies with long follow-up time, and it can bias study results unless handled carefully. A double-sampling design allocates additional resources to pursue a subsample of the dropouts and find out their outcomes, which can address potential biases due to non-ignorable dropout. It is desirable to construct semiparametric estimators for the double-sampling design because of their robustness properties. However, obtaining such semiparametric estimators remains a challenge due to the requirement of the analytic form of the efficient influence function (EIF), the …
In this paper we propose and study a general class of Gaussian Semiparametric Estimators (GSE) of the fractional differencing parameter in the context of long-range dependent multivariate time series. We establish large sample properties of the estimator without assuming Gaussianity. The class of models considered here satisfies simple conditions on the spectral density function, restricted to a small neighborhood of the zero frequency and includes important class of VARFIMA processes. We also present a simulation study to assess the finite sample properties of the proposed estimator based on …
We consider in this paper the semiparametric mixture of two distributions equal up to a shift parameter. The model is said to be semiparametric in the sense that the mixed distribution is not supposed to belong to a parametric family. In order to insure the identifiability of the model it is assumed that the mixed distribution is symmetric, the model being then defined by the mixing proportion, two location parameters, and the probability density function of the mixed distribution. We propose a new class of M-estimators of these parameters based on a Fourier approach, and prove that they are s…
We formulate nonparametric and semiparametric hypothesis testing of multivariate stationary linear time series in a unified fashion and propose new test statistics based on estimators of the spectral density matrix. The limiting distributions of these test statistics under null hypotheses are always normal distributions, and they can be implemented easily for practical use. If null hypotheses are false, as the sample size goes to infinity, they diverge to infinity and consequently are consistent tests for any alternative. The approach can be applied to various null hypotheses such as the indep…
Motivated by the analysis of a Positron Emission Tomography (PET) imaging data considered in Bowen et al. (2012), we introduce a semiparametric topographical mixture model able to capture the characteristics of dichotomous shifted response-type experiments. We propose a local estimation procedure, based on the symmetry of the local noise, for the proportion and locations functions involved in the proposed model. We establish under mild conditions the minimax properties and asymptotic normality of our estimators when Monte Carlo simulations are conducted to examine their finite sample performan…
Inference over tails is performed by applying only the results of extreme value theory. Whilst such theory is well defined and flexible enough in the univariate case, multivariate inferential methods often require the imposition of arbitrary constraints not fully justifed by the underlying theory. In contrast, our approach uses only the constraints imposed by theory. We build on previous, theoretically justified work for marginal exceedances over a high, unknown threshold, by combining it with flexible, semiparametric copulae specifications to investigate extreme dependence. Whilst giving prob…
Copulas are popular as models for multivariate dependence because they allow the marginal densities and the joint dependence to be modeled separately. However, they usually require that the transformation from uniform marginals to the marginals of the joint dependence structure is known. This can only be done for a restricted set of copulas, e.g. a normal copula. Our article introduces copula-type estimators for flexible multivariate density estimation which also allow the marginal densities to be modeled separately from the joint dependence, as in copula modeling, but overcomes the lack of fl…
Albeit worryingly underrated in the recent literature on machine learning in general (and, on deep learning in particular), multivariate density estimation is a fundamental task in many applications, at least implicitly, and still an open issue. With a few exceptions, deep neural networks (DNNs) have seldom been applied to density estimation, mostly due to the unsupervised nature of the estimation task, and (especially) due to the need for constrained training algorithms that ended up realizing proper probabilistic models that satisfy Kolmogorov's axioms. Moreover, in spite of the well-known i…
We consider a semiparametric mixture of two univariate density functions where one of them is known while the weight and the other function are unknown. Such mixtures have a history of application to the problem of detecting differentially expressed genes under two or more conditions in microarray data. Until now, some additional knowledge about the unknown component (e.g. the fact that it belongs to a location family) has been assumed. As opposed to this approach, we do not assume any additional structure on the unknown density function. For this mixture model, we derive a new sufficient iden…
The classical multivariate extreme-value theory concerns the modeling of extremes in a multivariate random sample, suggesting the use of max-stable distributions. In this work, the classical theory is extended to the case where aggregated data, such as maxima of a random number of observations, are considered. We derive a limit theorem concerning the attractors for the distributions of the aggregated data, which boil down to a new family of max-stable distributions. We also connect the extremal dependence structure of classical max-stable distributions and that of our new family of max-stable …
Our article addresses the problem of flexibly estimating a multivariate density while also attempting to estimate its marginals correctly. We do so by proposing two new estimators that try to capture the best features of mixture of normals and copula estimators while avoiding some of their weaknesses. The first estimator we propose is a mixture of normals copula model that is a flexible alternative to parametric copula models such as the normal and t copula. The second is a marginally adapted mixture of normals estimator that improves on the standard mixture of normals by using information con…
For extreme value estimation we propose to use a model with a Dirichlet process mixture of gamma densities in the center and generalized Pareto densities for the tails. Due to the randomness in the center and a heavy tailed density in the tails density estimation and posterior inference for high quantiles are possible. The approach can be used in a "default" manner on the positive reals because it works when prior information is unavailable. The proposed model can be easy to implement and a sensitivity analysis is provided. We applied the proposed model for simulated and real data sets.
Predictive recursion is an accurate and computationally efficient algorithm for nonparametric estimation of mixing densities in mixture models. In semiparametric mixture models, however, the algorithm fails to account for any uncertainty in the additional unknown structural parameter. As an alternative to existing profile likelihood methods, we treat predictive recursion as a filter approximation to fitting a fully Bayes model, whereby an approximate marginal likelihood of the structural parameter emerges and can be used for inference. We call this the predictive recursion marginal likelihood.…
We review the Bayesian theory of semiparametric inference following Bickel and Kleijn (2012) and Kleijn and Knapik (2013). After an overview of efficiency in parametric and semiparametric estimation problems, we consider the Bernstein-von Mises theorem (see, e.g., Le Cam and Yang (1990)) and generalize it to (LAN) regular and (LAE) irregular semiparametric estimation problems. We formulate a version of the semiparametric Bernstein-von Mises theorem that does not depend on least-favourable submodels, thus bypassing the most restrictive condition in the presentation of Bickel and Kleijn (2012). …
In a smooth semiparametric model, the marginal posterior distribution of the finite dimensional parameter of interest is expected to be asymptotically equivalent to the sampling distribution of frequentist's efficient estimators. This is the assertion of the so-called Bernstein-von Mises theorem, and recently, it has been proved in many interesting semiparametric models. In this thesis, we consider the semiparametric Bernstein-von Mises theorem in some models which have symmetric errors. The simplest example of these models is the symmetric location model that has 1-dimensional location parame…
Often of primary interest in the analysis of multivariate data are the copula parameters describing the dependence among the variables, rather than the univariate marginal distributions. Since the ranks of a multivariate dataset are invariant to changes in the univariate marginal distributions, rank-based estimators are natural candidates for semiparametric copula estimation. Asymptotic information bounds for such estimators can be obtained from an asymptotic analysis of the rank likelihood, that is, the probability of the multivariate ranks. In this article, we obtain limiting normal distribu…
