Multimodal medical image fusion is a crucial task that combines complementary information from different imaging modalities into a unified representation, thereby enhancing diagnostic accuracy and treatment planning. While deep learning methods, particularly Convolutional Neural Networks (CNNs) and Transformers, have significantly advanced fusion performance, some of the existing CNN-based methods fall short in capturing fine-grained multiscale and edge features, leading to suboptimal feature integration. Transformer-based models, on the other hand, are computationally intensive in both the training and fusion stages, making them impractical for real-time clinical use. Moreover, the clinical application of fused images remains unexplored. In this paper, we propose a novel CNN-based architecture that addresses these limitations by introducing a Dilated Residual Attention Network Module for effective multiscale feature extraction, coupled with a gradient operator to enhance edge detail learning. To ensure fast and efficient fusion, we present a parameter-free fusion strategy based on the weighted nuclear norm of softmax, which requires no additional computations during training or inference. Extensive experiments, including a downstream brain tumor classification task, demonstrate that our approach outperforms various baseline methods in terms of visual quality, texture preservation, and fusion speed, making it a possible practical solution for real-world clinical applications. The code will be released at https://github.com/simonZhou86/en_dran.
College of Computer Science Chongqing University（重庆大学计算机学院）
Image denoising is a classical problem in low level computer vision. Model-based optimization methods and deep learning approaches have been the two main strategies for solving the problem. Model-based optimization methods are flexible for handling different inverse problems but are usually time-consuming. In contrast, deep learning methods have fast testing speed but the performance of these CNNs is still inferior. To address this issue, here we propose a novel deep residual learning model that combines the dilated residual convolution and multi-scale convolution groups. Due to the complex pa…
Nanjing University of Information Science and Technology（南京信息工程大学）
Magnetic resonance imaging (MRI) reconstruction is an active inverse problem which can be addressed by conventional compressed sensing (CS) MRI algorithms that exploit the sparse nature of MRI in an iterative optimization-based manner. However, two main drawbacks of iterative optimization-based CSMRI methods are time-consuming and are limited in model capacity. Meanwhile, one main challenge for recent deep learning-based CSMRI is the trade-off between model performance and network size. To address the above issues, we develop a new multi-scale dilated network for MRI reconstruction with high s…
Variations of deep neural networks such as convolutional neural network (CNN) have been successfully applied to image denoising. The goal is to automatically learn a mapping from a noisy image to a clean image given training data consisting of pairs of noisy and clean images. Most existing CNN models for image denoising have many layers. In such cases, the models involve a large amount of parameters and are computationally expensive to train. In this paper, we develop a dilated residual CNN for Gaussian image denoising. Compared with the recently proposed residual denoiser, our method can achi…
We propose to learn a fully-convolutional network model that consists of a Chain of Identity Mapping Modules and residual on the residual architecture for image denoising. Our network structure possesses three distinctive features that are important for the noise removal task. Firstly, each unit employs identity mappings as the skip connections and receives pre-activated input to preserve the gradient magnitude propagated in both the forward and backward directions. Secondly, by utilizing dilated kernels for the convolution layers in the residual branch, each neuron in the last convolution lay…
Massachusetts General Hospital（麻省总医院）；Harvard Medical School（哈佛医学院）
This paper proposes a novel U-Net variant using stacked dilated convolutions for medical image segmentation (SDU-Net). SDU-Net adopts the architecture of vanilla U-Net with modifications in the encoder and decoder operations (an operation indicates all the processing for feature maps of the same resolution). Unlike vanilla U-Net which incorporates two standard convolutions in each encoder/decoder operation, SDU-Net uses one standard convolution followed by multiple dilated convolutions and concatenates all dilated convolution outputs as input to the next operation. Experiments showed that SDU-…
In this report, I investigate the use of end-to-end deep residual learning with dilated convolutions for myocardial infarction (MI) detection and localization from electrocardiogram (ECG) signals. Although deep residual learning has already been applied to MI detection and localization, I propose a more accurate system that distinguishes among a higher number (i.e., six) of MI locations. Inspired by speech waveform processing with neural networks, I found a more robust front-end than directly arranging the multi-lead ECG signal into an input matrix consisting of the use of a single one-dimensi…
University of Cambridge（剑桥大学）；Imperial College London（帝国理工学院）；Royal Brompton Hospital（皇家布朗普顿医院）
Super-resolution plays an essential role in medical imaging because it provides an alternative way to achieve high spatial resolutions and image quality with no extra acquisition costs. In the past few decades, the rapid development of deep neural networks has promoted super-resolution performance with novel network architectures, loss functions and evaluation metrics. Specifically, vision transformers dominate a broad range of computer vision tasks, but challenges still exist when applying them to low-level medical image processing tasks. This paper proposes an efficient vision transformer wi…
The extraction and proper utilization of convolution neural network (CNN) features have a significant impact on the performance of image super-resolution (SR). Although CNN features contain both the spatial and channel information, current deep techniques on SR often suffer to maximize performance due to using either the spatial or channel information. Moreover, they integrate such information within a deep or wide network rather than exploiting all the available features, eventually resulting in high computational complexity. To address these issues, we present a binarized feature fusion (BFF…
Birla Institute of Technology Science Pilani（比尔拉理工学院皮拉尼分校）
In this work, we present Eformer - Edge enhancement based transformer, a novel architecture that builds an encoder-decoder network using transformer blocks for medical image denoising. Non-overlapping window-based self-attention is used in the transformer block that reduces computational requirements. This work further incorporates learnable Sobel-Feldman operators to enhance edges in the image and propose an effective way to concatenate them in the intermediate layers of our architecture. The experimental analysis is conducted by comparing deterministic learning and residual learning for the …
Automatic segmentation of organs-at-risk (OAR) in computed tomography (CT) is an essential part of planning effective treatment strategies to combat lung and esophageal cancer. Accurate segmentation of organs surrounding tumours helps account for the variation in position and morphology inherent across patients, thereby facilitating adaptive and computer-assisted radiotherapy. Although manual delineation of OARs is still highly prevalent, it is prone to errors due to complex variations in the shape and position of organs across patients, and low soft tissue contrast between neighbouring organs…
Osaka Electro-Communication University（大阪电气通信大学）；Ritsumeikan University（立命馆大学）；Shiga University of Medical Science（滋贺医科大学）
Deep learning techniques have led to state-of-the-art image super resolution with natural images. Normally, pairs of high-resolution and low-resolution images are used to train the deep learning models. These techniques have also been applied to medical image super-resolution. The characteristics of medical images differ significantly from natural images in several ways. First, it is difficult to obtain high-resolution images for training in real clinical applications due to the limitations of imaging systems and clinical requirements. Second, other modal high-resolution images are available (…
Télécom Paris, Institut Polytechnique de Paris（巴黎理工学院巴黎电信学院）；CNRS（法国国家科学研究中心）
In medical imaging, most of the image registration methods implicitly assume a one-to-one correspondence between the source and target images (i.e., diffeomorphism). However, this is not necessarily the case when dealing with pathological medical images (e.g., presence of a tumor, lesion, etc.). To cope with this issue, the Metamorphosis model has been proposed. It modifies both the shape and the appearance of an image to deal with the geometrical and topological differences. However, the high computational time and load have hampered its applications so far. Here, we propose a deep residual l…
Khalifa University（哈利法大学）；Beihang University（北京航空航天大学）；University of Louisville（路易斯维尔大学）
Prostate cancer (PCa) is the second deadliest form of cancer in males, and it can be clinically graded by examining the structural representations of Gleason tissues. This paper proposes \RV{a new method} for segmenting the Gleason tissues \RV{(patch-wise) in order to grade PCa from the whole slide images (WSI).} Also, the proposed approach encompasses two main contributions: 1) A synergy of hybrid dilation factors and hierarchical decomposition of latent space representation for effective Gleason tissues extraction, and 2) A three-tiered loss function which can penalize different semantic seg…
Australian National University（澳大利亚国立大学）；CSIRO Data61（澳大利亚联邦科学与工业研究组织 Data61）
We propose to learn a fully-convolutional network model that consists of a Chain of Identity Mapping Modules (CIMM) for image denoising. The CIMM structure possesses two distinctive features that are important for the noise removal task. Firstly, each residual unit employs identity mappings as the skip connections and receives pre-activated input in order to preserve the gradient magnitude propagated in both the forward and backward directions. Secondly, by utilizing dilated kernels for the convolution layers in the residual branch, in other words within an identity mapping module, each neuron…
Fingerprint image denoising is a very important step in fingerprint identification. to improve the denoising effect of fingerprint image,we have designs a fingerprint denoising algorithm based on deep encoder-decoder network,which encoder subnet to learn the fingerprint features of noisy images.the decoder subnet reconstructs the original fingerprint image based on the features to achieve denoising, while using the dilated convolution in the network to increase the receptor field without increasing the complexity and improve the network inference speed. In addition, feature fusion at different…
University of Florida（佛罗里达大学）；US Anesthesia Partners（美国麻醉伙伴公司）
Automated object recognition in medical images can facilitate medical diagnosis and treatment. In this paper, we automatically segmented supraclavicular nerves in ultrasound images to assist in injecting peripheral nerve blocks. Nerve blocks are generally used for pain treatment after surgery, where ultrasound guidance is used to inject local anesthetics next to target nerves. This treatment blocks the transmission of pain signals to the brain, which can help improve the rate of recovery from surgery and significantly decrease the requirement for postoperative opioids. However, Ultrasound Guid…
Harbin Institute of Technology, Shenzhen（哈尔滨工业大学（深圳））；Guangdong University of Technology（广东工业大学）；Heilongjiang Academy of Sciences（黑龙江省科学院）
Owing to flexible architectures of deep convolutional neural networks (CNNs), CNNs are successfully used for image denoising. However, they suffer from the following drawbacks: (i) deep network architecture is very difficult to train. (ii) Deeper networks face the challenge of performance saturation. In this study, the authors propose a novel method called enhanced convolutional neural denoising network (ECNDNet). Specifically, they use residual learning and batch normalisation techniques to address the problem of training difficulties and accelerate the convergence of the network. In addition…
UNIVERSITY OF CALIFORNIA（加利福尼亚大学）；LOS ANGELES（洛杉矶）
Image segmentation is widely used in a variety of computer vision tasks, such as object localization and recognition, boundary detection, and medical imaging. This thesis proposes deep learning architectures to improve automatic object localization and boundary delineation for salient object segmentation in natural images and for 2D medical image segmentation. First, we propose and evaluate a novel dilated dense encoder-decoder architecture with a custom dilated spatial pyramid pooling block to accurately localize and delineate boundaries for salient object segmentation. The dilation offers be…
Deep Learning Framework with Multi-Head Dilated Encoders for Enhanced Segmentation of Cervical Cancer on Multiparametric Magnetic Resonance Imaging
the Institute of Cancer Research（癌症研究所）；The Royal Marsden Hospital（皇家马斯登医院）；Iuliu Hatieganu University of Medicine and Pharmacy（尤利乌·哈蒂耶加努医药大学）；Chang Gung Memorial Hospital（长庚纪念医院）；Chang Gung University（长庚大学）
Automated and accurate 3D medical image segmentation plays an essential role in assisting medical professionals to evaluate disease progresses and make fast therapeutic schedules. Although deep convolutional neural networks (DCNNs) have widely applied to this task, the accuracy of these models still need to be further improved mainly due to their limited ability to 3D context perception. In this paper, we propose the 3D context residual network (ConResNet) for the accurate segmentation of 3D medical images. This model consists of an encoder, a segmentation decoder, and a context residual decod…
Bilkent University（比尔肯特大学）；National Magnetic Resonance Research Center (UMRAM)（国家磁共振研究中心（UMRAM））；Sabuncu Brain Research Center（萨本库脑研究中心）
Generative adversarial models with convolutional neural network (CNN) backbones have recently been established as state-of-the-art in numerous medical image synthesis tasks. However, CNNs are designed to perform local processing with compact filters, and this inductive bias compromises learning of contextual features. Here, we propose a novel generative adversarial approach for medical image synthesis, ResViT, that leverages the contextual sensitivity of vision transformers along with the precision of convolution operators and realism of adversarial learning.} ResViT's generator employs a cent…
A Residual Multi-task Network for Joint Classification and Regression in Medical Imaging
School of Computer Science and Technology, University of Chinese Academy of Sciences（中国科学院大学计算机科学与技术学院）；College of Surveying and GeoInformatics, Tongji University（同济大学测绘与地理信息学院）；School of Computer Science, Shaanxi Normal University（陕西师范大学计算机学院）
Deep Convolutional Neural Networks (CNNs) i.e. Residual Networks (ResNets) have been used successfully for many computer vision tasks, but are difficult to scale to 3D volumetric medical data. Memory is increasingly often the bottleneck when training 3D Convolutional Neural Networks (CNNs). Recently, invertible neural networks have been applied to significantly reduce activation memory footprint when training neural networks with backpropagation thanks to the invertible functions that allow retrieving its input from its output without storing intermediate activations in memory to perform the b…
OpenMined；Manifold Computing Group（曼尼福德计算集团）；Ford R&A（福特研发部门）；Harvard University（哈佛大学）；Indian Institute of Technology Jodhpur（印度理工学院焦特布尔分校）；University of Oxford（牛津大学）
In this paper we measure the effectiveness of $ε$-Differential Privacy (DP) when applied to medical imaging. We compare two robust differential privacy mechanisms: Local-DP and DP-SGD and benchmark their performance when analyzing medical imagery records. We analyze the trade-off between the model's accuracy and the level of privacy it guarantees, and also take a closer look to evaluate how useful these theoretical privacy guarantees actually prove to be in the real world medical setting.
The shapes and morphology of the organs and tissues are important prior knowledge in medical imaging recognition and segmentation. The morphological operation is a well-known method for morphological feature extraction. As the morphological operation is performed well in hand-crafted image segmentation techniques, it is also promising to design an approach to approximate morphological operation in the convolutional networks. However, using the traditional convolutional neural network as a black-box is usually hard to specify the morphological operation action. Here, we introduced a 3D morpholo…
Indian Institute of Information Technology Allahabad（印度阿拉哈巴德信息技术学院）
In this work, we propose a two-stage autoencoder based compressor-decompressor framework for compressing malaria RBC cell image patches. We know that the medical images used for disease diagnosis are around multiple gigabytes size, which is quite huge. The proposed residual-based dual autoencoder network is trained to extract the unique features which are then used to reconstruct the original image through the decompressor module. The two latent space representations (first for the original image and second for the residual image) are used to rebuild the final original image. Color-SSIM has be…
DoubleU-NetPlus: A Novel Attention and Context Guided Dual U-Net with Multi-Scale Residual Feature Fusion Network for Semantic Segmentation of Medical Images
United International University（联合国际大学）；Stamford University Bangladesh（孟加拉国斯坦福大学）
U-Net has been providing state-of-the-art performance in many medical image segmentation problems. Many modifications have been proposed for U-Net, such as attention U-Net, recurrent residual convolutional U-Net (R2-UNet), and U-Net with residual blocks or blocks with dense connections. However, all these modifications have an encoder-decoder structure with skip connections, and the number of paths for information flow is limited. We propose LadderNet in this paper, which can be viewed as a chain of multiple U-Nets. Instead of only one pair of encoder branch and decoder branch in U-Net, a Ladd…
MLRU++: Multiscale Lightweight Residual UNETR++ with Attention for Efficient 3D Medical Image Segmentation
AI Research Lab, Department of Computer Science（人工智能研究实验室、计算机科学系）；Biomedical & Translational Sciences, Sanford School of Medicine（生物医学与转化科学、桑福德医学院）；University Of South Dakota（南达科他大学）
Location information is proven to benefit the deep learning models on capturing the manifold structure of target objects, and accordingly boosts the accuracy of medical image segmentation. However, most existing methods encode the location information in an implicit way, e.g. the distance transform maps, which describe the relative distance from each pixel to the contour boundary, for the network to learn. These implicit approaches do not fully exploit the position information (i.e. absolute location) of targets. In this paper, we propose a novel loss function, namely residual moment (RM) loss…
Tianjin University（天津大学）；CSIRO Data61（澳大利亚联邦科学与工业研究组织Data61）；La Trobe University（乐卓博大学）；Tianjin University of Traditional Chinese Medicine（天津中医药大学）
The insufficiency of annotated medical imaging scans for cancer makes it challenging to train and validate data-hungry deep learning models in precision oncology. We propose a new richer generative adversarial network for free-form 3D tumor/lesion synthesis in computed tomography (CT) images. The network is composed of a new richer convolutional feature enhanced dilated-gated generator (RicherDG) and a hybrid loss function. The RicherDG has dilated-gated convolution layers to enable tumor-painting and to enlarge perceptive fields; and it has a novel richer convolutional feature association bra…
University of Dongguk（东国大学）；Dongguk University Ilsan Hospital（东国大学一山医院）
Increasing numbers of patients with disabilities or elderly people with mobility issues often suffer from a pressure ulcer. The affected areas need regular checks, but they have a difficulty in accessing a hospital. Some remote diagnosis systems are being used for them, but there are limitations in checking a patient's status regularly. In this paper, we present a remote medical assistant that can help pressure ulcer management with image processing techniques. The proposed system includes a mobile application with a deep learning model for wound segmentation and analysis. As there are not eno…
COMSATS University Islamabad（伊斯兰堡COMSATS大学）；Umeå University（于默奥大学）
U-Net is a widely adopted neural network in the domain of medical image segmentation. Despite its quick embracement by the medical imaging community, its performance suffers on complicated datasets. The problem can be ascribed to its simple feature extracting blocks: encoder/decoder, and the semantic gap between encoder and decoder. Variants of U-Net (such as R2U-Net) have been proposed to address the problem of simple feature extracting blocks by making the network deeper, but it does not deal with the semantic gap problem. On the other hand, another variant UNET++ deals with the semantic gap…
The Hong Kong Polytechnic University（香港理工大学）；University of Oxford（牛津大学）
Automatic medical image segmentation based on Computed Tomography (CT) has been widely applied for computer-aided surgery as a prerequisite. With the development of deep learning technologies, deep convolutional neural networks (DCNNs) have shown robust performance in automated semantic segmentation of medical images. However, semantic segmentation algorithms based on DCNNs still meet the challenges of feature loss between encoder and decoder, multi-scale object, restricted field of view of filters, and lack of medical image data. This paper proposes a novel algorithm for automated vertebrae s…
Satellite images are often contaminated by clouds. Cloud removal has received much attention due to the wide range of satellite image applications. As the clouds thicken, the process of removing the clouds becomes more challenging. In such cases, using auxiliary images such as near-infrared or synthetic aperture radar (SAR) for reconstructing is common. In this study, we attempt to solve the problem using two generative adversarial networks (GANs). The first translates SAR images into optical images, and the second removes clouds using the translated images of prior GAN. Also, we propose dilat…
Development of Skip Connection in Deep Neural Networks for Computer Vision and Medical Image Analysis: A Survey
School of Computer Science and Engineering, Hubei Key Laboratory of Intelligent Robot, Wuhan Institute of Technology（计算机科学与工程学院、智能机器人湖北省重点实验室、武汉理工大学）；School of Computer Science, Wuhan University（计算机科学学院、武汉大学）
Currently, developments of deep learning techniques are providing instrumental to identify, classify, and quantify patterns in medical images. Segmentation is one of the important applications in medical image analysis. In this regard, U-Net is the predominant approach to medical image segmentation tasks. However, we found that those U-Net based models have limitations in several aspects, for example, millions of parameters in the U-Net consuming considerable computation resource and memory, lack of global information, and missing some tough objects. Therefore, we applied two modifications to …
University of Oxford（牛津大学）；Beihang University（北京航空航天大学）
Segmentation algorithms for medical images are widely studied for various clinical and research purposes. In this paper, we propose a new and efficient method for medical image segmentation under noisy labels. The method operates under a deep learning paradigm, incorporating four novel contributions. Firstly, a residual interconnection is explored in different scale encoders to transfer gradient information efficiently. Secondly, four copy-and-crop connections are replaced by residual-block-based concatenation to alleviate the disparity between encoders and decoders. Thirdly, convolutional att…
Applied Science Private University（应用科学私立大学）；Jadara University（贾达拉大学）；Princess Sumaya University for Technology（苏玛雅公主科技大学）；King Hussein Medical Center（侯赛因国王医疗中心）
The biliary tree is a network of tubes that connects the liver to the gallbladder, an organ right beneath it. The bile duct is the major tube in the biliary tree. The dilatation of a bile duct is a key indicator for more major problems in the human body, such as stones and tumors, which are frequently caused by the pancreas or the papilla of vater. The detection of bile duct dilatation can be challenging for beginner or untrained medical personnel in many circumstances. Even professionals are unable to detect bile duct dilatation with the naked eye. This research presents a unique vision-based…
