As countries look towards re-opening of economic activities amidst the ongoing COVID-19 pandemic, ensuring public health has been challenging. While contact tracing only aims to track past activities of infected users, one path to safe reopening is to develop reliable spatiotemporal risk scores to indicate the propensity of the disease. Existing works which aim to develop risk scores either rely on compartmental model-based reproduction numbers (which assume uniform population mixing) or develop coarse-grain spatial scores based on reproduction number (R0) and macro-level density-based mobility statistics. Instead, in this paper, we develop a Hawkes process-based technique to assign relatively fine-grain spatial and temporal risk scores by leveraging high-resolution mobility data based on cell-phone originated location signals. While COVID-19 risk scores also depend on a number of factors specific to an individual, including demography and existing medical conditions, the primary mode of disease transmission is via physical proximity and contact. Therefore, we focus on developing risk scores based on location density and mobility behaviour. We demonstrate the efficacy of the developed risk scores via simulation based on real-world mobility data. Our results show that fine-grain spatiotemporal risk scores based on high-resolution mobility data can provide useful insights and facilitate safe re-opening.
With COVID-19 affecting every country globally and changing everyday life, the ability to forecast the spread of the disease is more important than any previous epidemic. The conventional methods of disease-spread modeling, compartmental models, are based on the assumption of spatiotemporal homogeneity of the spread of the virus, which may cause forecasting to underperform, especially at high spatial resolutions. In this paper we approach the forecasting task with an alternative technique - spatiotemporal machine learning. We present COVID-LSTM, a data-driven model based on a Long Short-term M…
The outbreaks of Coronavirus Disease 2019 (COVID-19) have impacted the world significantly. Modeling the trend of infection and real-time forecasting of cases can help decision making and control of the disease spread. However, data-driven methods such as recurrent neural networks (RNN) can perform poorly due to limited daily samples in time. In this work, we develop an integrated spatiotemporal model based on the epidemic differential equations (SIR) and RNN. The former after simplification and discretization is a compact model of temporal infection trend of a region while the latter models t…
University of Maryland Baltimore School of Medicine（马里兰大学巴尔的摩医学院）
Background: The novel coronavirus, COVID-19, was first detected in the United States in January 2020. To curb the spread of the disease in mid-March, different states issued mandatory stay-at-home (SAH) orders. These nonpharmaceutical interventions were mandated based on prior experiences, such as the 1918 influenza epidemic. Hence, we decided to study the impact of restrictions on mobility on reducing COVID-19 transmission. Methods: We designed an ecological time series study with our exposure variable as Mobility patterns in the state of Maryland for March- December 2020 and our outcome vari…
Delft University of Technology（代尔夫特理工大学）；ETH Zürich（苏黎世联邦理工学院）；University of Strathclyde（思克莱德大学）；Universidade de Lisboa（里斯本大学）
With people constantly migrating to different urban areas, our mobility needs for work, services and leisure are transforming rapidly. The changing urban demographics pose several challenges for the efficient management of transit services. To forecast transit demand, planners often resort to sociological investigations or modelling that are either difficult to obtain, inaccurate or outdated. How can we then estimate the variegated demand for mobility? We propose a simple method to identify the spatiotemporal demand for public transit in a city. Using a Gaussian mixture model, we decompose emp…
Epidemic modeling is an essential tool to understand the spread of the novel coronavirus and ultimately assist in disease prevention, policymaking, and resource allocation. In this article, we establish a state of the art interface between classic mathematical and statistical models and propose a novel space-time epidemic modeling framework to study the spatial-temporal pattern in the spread of infectious disease. We propose a quasi-likelihood approach via the penalized spline approximation and alternatively reweighted least-squares technique to estimate the model. Furthermore, we provide a sh…
Pacific Northwest National Laboratory（太平洋西北国家实验室）；Michigan State University（密歇根州立大学）
Since the increasing outspread of COVID-19 in the U.S., with the highest number of confirmed cases and deaths in the world as of September 2020, most states in the country have enforced travel restrictions resulting in sharp reductions in mobility. However, the overall impact and long-term implications of this crisis to travel and mobility remain uncertain. To this end, this study develops an analytical framework that determines and analyzes the most dominant factors impacting human mobility and travel in the U.S. during this pandemic. In particular, the study uses Granger causality to determi…
In response to the novel coronavirus disease (COVID-19), governments have introduced severe policy measures with substantial effects on human behavior. Here, we perform a large-scale, spatio-temporal analysis of human mobility during the COVID-19 epidemic. We derive human mobility from anonymized, aggregated telecommunication data in a nationwide setting (Switzerland; February 10 - April 26, 2020), consisting of ~1.5 billion trips. In comparison to the same time period from 2019, human movement in Switzerland dropped by 49.1%. The strongest reduction is linked to bans on gatherings of more tha…
Currently, Brazil has one of the fastest increasing COVID-19 epidemics in the world, that has caused at least 94 thousand confirmed deaths until now. The city of Sao Paulo is particularly vulnerable because it is the most populous in the country. Analyzing the spatiotemporal dynamics of COVID-19 is important to help the urgent need to integrate better actions to face the pandemic. Thus, this study aimed to analyze the COVID-19 mortality, from March to July 2020, considering the spatio-time architectures, the socio-economic context of the population, and using a fine granular level, in the most…
Ludwig Maximilian Universität（路德维希-马克西米利安大学）；Helmholtz Zentrum München – German Research Center for Environmental Health（亥姆霍兹慕尼黑中心——德国环境健康研究中心）
During 2020, the infection rate of COVID-19 has been investigated by many scholars from different research fields. In this context, reliable and interpretable forecasts of disease incidents are a vital tool for policymakers to manage healthcare resources. Several experts have called for the necessity to account for human mobility to explain the spread of COVID-19. Existing approaches are often applying standard models of the respective research field. This habit, however, often comes along with certain restrictions. For instance, most statistical or epidemiological models cannot directly incor…
Social distancing and stay-at-home are among the few measures that are known to be effective in checking the spread of a pandemic such as COVID-19 in a given population. The patterns of dependency between such measures and their effects on disease incidence may vary dynamically and across different populations. We described a new computational framework to measure and compare the temporal relationships between human mobility and new cases of COVID-19 across more than 150 cities of the United States with relatively high incidence of the disease. We used a novel application of Optimal Transport …
Since December 2019, the world has been witnessing the gigantic effect of an unprecedented global pandemic called Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) - COVID-19. So far, 38,619,674 confirmed cases and 1,093,522 confirmed deaths due to COVID-19 have been reported. In the United States (US), the cases and deaths are recorded as 7,833,851 and 215,199. Several timely researches have discussed the local and global effects of the confounding factors on COVID-19 casualties in the US. However, most of these studies considered little about the time varying associations between an…
To manage the COVID-19 epidemic effectively, decision-makers in public health need accurate forecasts of case numbers. A potential near real-time predictor of future case numbers is human mobility; however, research on the predictive power of mobility is lacking. To fill this gap, we introduce a novel model for epidemic forecasting based on mobility data, called mobility marked Hawkes model. The proposed model consists of three components: (1) A Hawkes process captures the transmission dynamics of infectious diseases. (2) A mark modulates the rate of infections, thus accounting for how the rep…
Correlation between weather and the transmission of SARS-CoV-2 may suggest its seasonality. Cointegration analysis can avoid spurious correlation among time series data. We examined the cointegration of virus transmission with daily temperature, dewpoint, and confounding factors of mobility measurements during the first year of the pandemic in the United States. We examined the cointegration of the effective reproductive rate, Rt, of the virus with the dewpoint at two meters, the temperature at two meters, Apple driving mobility, and Google workplace mobility measurements. We found that dewpoi…
Potential Landscapes Reveal Spatiotemporal Structure in Urban Mobility: Hodge Decomposition and Principal Component Analysis of Tokyo Before and During COVID-19
I present three types of applications of generalized additive models (GAMs) to COVID-19 mortality rates in the US for the purpose of advancing methods to document inequities with respect to which communities suffered disproportionate COVID-19 mortality rates at specific times during the first three years of the pandemic. First, GAMs can be used to describe the changing relationship between COVID-19 mortality and county-level covariates (sociodemographic, economic, and political metrics) over time. Second, GAMs can be used to perform spatiotemporal smoothing that pools information over time and…
Background: Studies have shown that human mobility is an important factor in dengue epidemiology. Changes in mobility resulting from COVID-19 pandemic set up a real-life situation to test this hypothesis. Our objective was to evaluate the effect of reduced mobility due to this pandemic in the occurrence of dengue in the state of São Paulo, Brazil. Method: It is an ecological study of time series, developed between January and August 2020. We use the number of confirmed dengue cases and residential mobility, on a daily basis, from secondary information sources. Mobility was represented by the d…
With the onset of COVID-19 and the resulting shelter in place guidelines combined with remote working practices, human mobility in 2020 has been dramatically impacted. Existing studies typically examine whether mobility in specific localities increases or decreases at specific points in time and relate these changes to certain pandemic and policy events. In this paper, we study mobility change in the US through a five-step process using mobility footprint data. (Step 1) Propose the delta Time Spent in Public Places (Delta-TSPP) as a measure to quantify daily changes in mobility for each US cou…
Predicting the number of infections in the anti-epidemic process is extremely beneficial to the government in developing anti-epidemic strategies, especially in fine-grained geographic units. Previous works focus on low spatial resolution prediction, e.g., county-level, and preprocess data to the same geographic level, which loses some useful information. In this paper, we propose a fine-grained population mobility data-based model (FGC-COVID) utilizing data of two geographic levels for community-level COVID-19 prediction. We use the population mobility data between Census Block Groups (CBGs),…
Spatiotemporal-Augmented Graph Neural Networks for Human Mobility Simulation
College of Computer Science, Zhejiang University（浙江大学计算机学院）；College of Software Technology, Zhejiang University（浙江大学软件技术学院）；State Key Laboratory of Blockchain and Security, Zhejiang University（浙江大学区块链与安全国家重点实验室）
The Hong Kong University of Science and Technology (Guangzhou)（香港科技大学（广州））；The Hong Kong University of Science and Technology（香港科技大学）；Tencent AI Lab（腾讯AI实验室）
Non-Pharmaceutical Interventions (NPIs), such as social gathering restrictions, have shown effectiveness to slow the transmission of COVID-19 by reducing the contact of people. To support policy-makers, multiple studies have first modeled human mobility via macro indicators (e.g., average daily travel distance) and then studied the effectiveness of NPIs. In this work, we focus on mobility modeling and, from a micro perspective, aim to predict locations that will be visited by COVID-19 cases. Since NPIs generally cause economic and societal loss, such a micro perspective prediction benefits gov…
The ongoing COVID-19 global pandemic is affecting every facet of human lives (e.g., public health, education, economy, transportation, and the environment). This novel pandemic and citywide implemented lockdown measures are affecting virus transmission, people's travel patterns, and air quality. Many studies have been conducted to predict the COVID-19 diffusion, assess the impacts of the pandemic on human mobility and air quality, and assess the impacts of lockdown measures on viral spread with a range of Machine Learning (ML) techniques. This review study aims to analyze results from past res…
Universidade Federal de São Paulo (UNIFESP)（圣保罗联邦大学）
In 2020, Brazil was the leading country in COVID-19 cases in Latin America, and capital cities were the most severely affected by the outbreak. Climates vary in Brazil due to the territorial extension of the country, its relief, geography, and other factors. Since the most common COVID-19 symptoms are related to the respiratory system, many researchers have studied the correlation between the number of COVID-19 cases with meteorological variables like temperature, humidity, rainfall, etc. Also, due to its high transmission rate, some researchers have analyzed the impact of human mobility on th…
European Commission Joint Research Centre（欧盟委员会联合研究中心）
This work introduces a new concept of functional areas called Mobility Functional Areas (MFAs), i.e., the geographic zones highly interconnected according to the analysis of mobile positioning data. The MFAs do not coincide necessarily with administrative borders as they are built observing natural human mobility and, therefore, they can be used to inform, in a bottom-up approach, local transportation, spatial planning, health and economic policies. After presenting the methodology behind the MFAs, this study focuses on the link between the COVID-19 pandemic and the MFAs in Austria. It emerges…
Virginia Tech（弗吉尼亚理工大学）；Mississippi State University（密西西比州立大学）
Modeling the spatiotemporal nature of the spread of infectious diseases can provide useful intuition in understanding the time-varying aspect of the disease spread and the underlying complex spatial dependency observed in people's mobility patterns. Besides, the county level multiple related time series information can be leveraged to make a forecast on an individual time series. Adding to this challenge is the fact that real-time data often deviates from the unimodal Gaussian distribution assumption and may show some complex mixed patterns. Motivated by this, we develop a deep learning-based …
University of Iowa（爱荷华大学）；University of Maryland（马里兰大学）；Worcester Polytechnic Institute（伍斯特理工学院）；University of Pittsburgh（匹兹堡大学）
Human mobility estimation is crucial during the COVID-19 pandemic due to its significant guidance for policymakers to make non-pharmaceutical interventions. While deep learning approaches outperform conventional estimation techniques on tasks with abundant training data, the continuously evolving pandemic poses a significant challenge to solving this problem due to data nonstationarity, limited observations, and complex social contexts. Prior works on mobility estimation either focus on a single city or lack the ability to model the spatio-temporal dependencies across cities and time periods. …
M-STAR: Multi-Scale Spatiotemporal Autoregression for Human Mobility Modeling
Department of Land Surveying and Geo-informatics, The Hong Kong Polytechnic University（土地测量与地理信息学系，香港理工大学）；Shenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences（深圳先进技术研究所，中国科学院）；Faculty of Computer Science and Control Engineering, Shenzhen University of Advanced Technology（计算机科学与控制工程学院，深圳先进技术大学）；School of Computer Science and Technology, Beijing Institute of Technology（计算机科学与技术学院，北京理工大学）
In this work, we examine a novel forecasting approach for COVID-19 case prediction that uses Graph Neural Networks and mobility data. In contrast to existing time series forecasting models, the proposed approach learns from a single large-scale spatio-temporal graph, where nodes represent the region-level human mobility, spatial edges represent the human mobility based inter-region connectivity, and temporal edges represent node features through time. We evaluate this approach on the US county level COVID-19 dataset, and demonstrate that the rich spatial and temporal information leveraged by t…
University of Science and Technology of China（中国科学技术大学）；Beijing Institute of Control Engineering（北京控制工程研究所）
The high dynamics and heterogeneous interactions in the complicated urban systems have raised the issue of uncertainty quantification in spatiotemporal human mobility, to support critical decision-makings in risk-aware web applications such as urban event prediction where fluctuations are of significant interests. Given the fact that uncertainty quantifies the potential variations around prediction results, traditional learning schemes always lack uncertainty labels, and conventional uncertainty quantification approaches mostly rely upon statistical estimations with Bayesian Neural Networks or…
Integrating Spatiotemporal Features in LSTM for Spatially Informed COVID-19 Hospitalization Forecasting
Heilbrunn Department of Population and Family Health, Columbia University Mailman School of Public Health（哥伦比亚大学流行病学与家庭健康系）；Department of Geography, University of Colorado（科罗拉多大学地理系）；Population Council（人口理事会）
University of California, Los Angeles（加利福尼亚大学洛杉矶分校）
Pandemic(epidemic) modeling, aiming at disease spreading analysis, has always been a popular research topic especially following the outbreak of COVID-19 in 2019. Some representative models including SIR-based deep learning prediction models have shown satisfactory performance. However, one major drawback for them is that they fall short in their long-term predictive ability. Although graph convolutional networks (GCN) also perform well, their edge representations do not contain complete information and it can lead to biases. Another drawback is that they usually use input features which they …
