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arXiv 2211.16629stat.AP
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使用广义可加模型理解US中县级COVID-19死亡率的社会、地理和经济不平等的复杂模式

Understanding Complex Patterns in Social, Geographic, and Economic Inequities in COVID-19 Mortality at the County Level in the US Using Generalized Additive Models

Christian Testa

摘要:

我介绍了广义可加模型(GAM)在美国COVID-19死亡率中的三种应用,目的是改进方法,以记录在大流行的前三年特定时间内社区遭受不成比例的COVID-19死亡率的不公平性。首先,GAM可用于描述COVID-19死亡率与县级协变量(社会人口统计、经济和政治指标)之间随时间变化的关系。其次,GAM可用于执行时空平滑,其汇集随时间和空间的信息,以解决由于小的人口计数或随机性而导致的统计不稳定性,从而产生平滑的动态潜在风险表面,该表面概括随时间与地理位置相关联的死亡率风险。第三,以平稳的时空风险曲面为条件,估计COVID-19死亡率与县级协变量的关联,可以更严格地考虑社会环境背景和政策可能如何影响COVID-19死亡率。这些方法中的每一种都为记录COVID-19死亡率的不平等提供了有价值的视角,通过解决哪些人群遭受了COVID-19死亡率的最严重负担的问题,同时考虑到疾病的非线性空间,时间和社会模式。

英文摘要:

I present three types of applications of generalized additive models (GAMs) to COVID-19 mortality rates in the US for the purpose of advancing methods to document inequities with respect to which communities suffered disproportionate COVID-19 mortality rates at specific times during the first three years of the pandemic. First, GAMs can be used to describe the changing relationship between COVID-19 mortality and county-level covariates (sociodemographic, economic, and political metrics) over time. Second, GAMs can be used to perform spatiotemporal smoothing that pools information over time and space to address statistical instability due to small population counts or stochasticity resulting in a smooth, dynamic latent risk surface summarizing the mortality risk associated with geographic locations over time. Third, estimation of COVID-19 mortality associations with county-level covariates conditional on a smooth spatiotemporal risk surface allows for more rigorous consideration of how socio-environmental contexts and policies may have impacted COVID-19 mortality. Each of these approaches provides a valuable perspective to documenting inequities in COVID-19 mortality by addressing the question of which populations have suffered the worst burden of COVID-19 mortality taking into account the nonlinear spatial, temporal, and social patterning of disease.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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