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arXiv 2205.13639cs.LGstat.AP
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基于模型预测控制函数连续时间贝叶斯网络的慢性疾病自我管理

A Model Predictive Control Functional Continuous Time Bayesian Network for Self-Management of Multiple Chronic Conditions

Northwestern University(西北大学);The University of Texas at San Antonio(德克萨斯大学圣安东尼奥分校);Florida State University(佛罗里达州立大学);The University of Texas Health Science Center at Houston(德克萨斯大学休斯顿健康科学中心)

Syed Hasib Akhter Faruqui, Adel Alaeddini, Jing Wang, Susan P Fisher-Hoch, Joseph B Mccormick, Julian Carvajal Rico

摘要:

多种慢性病(MCC)是现代最大的挑战之一。MCC的演变遵循一个复杂的随机过程,受到各种风险因素的影响,从预先存在的疾病到可改变的生活方式行为因素(例如饮食,运动习惯,吸烟,饮酒等)。不可改变的社会人口因素(例如,年龄、性别、教育、婚姻状况等)。MCC患者患新慢性病和死亡的风险增加。本文提出了一种模型预测控制功能连续时间贝叶斯网络,一种在线递归方法来检查各种生活方式行为变化对MCC出现轨迹的影响,并生成策略,以最大限度地减少个体患者慢性疾病进展的风险。所提出的方法进行了验证的基础上卡梅隆县西班牙裔队列(CCHC)数据集,其中共有385例患者。该数据集检查了5种慢性疾病(糖尿病,肥胖,认知障碍,高脂血症和高血压)的出现,基于代表生活方式行为(饮食,运动习惯,吸烟,饮酒)的4个可修改的风险因素和4个不可修改的风险因素,包括社会人口统计信息(年龄,性别,教育,婚姻状况)。所提出的方法在不同的场景下进行测试(例如,年龄组,先前存在MCC),证明了改善生活方式行为危险因素以抵消MCC演变的有效干预策略。

英文摘要:

Multiple chronic conditions (MCC) are one of the biggest challenges of modern times. The evolution of MCC follows a complex stochastic process that is influenced by a variety of risk factors, ranging from pre-existing conditions to modifiable lifestyle behavioral factors (e.g. diet, exercise habits, tobacco use, alcohol use, etc.) to non-modifiable socio-demographic factors (e.g., age, gender, education, marital status, etc.). People with MCC are at an increased risk of new chronic conditions and mortality. This paper proposes a model predictive control functional continuous time Bayesian network, an online recursive method to examine the impact of various lifestyle behavioral changes on the emergence trajectories of MCC and generate strategies to minimize the risk of progression of chronic conditions in individual patients. The proposed method is validated based on the Cameron county Hispanic cohort (CCHC) dataset, which has a total of 385 patients. The dataset examines the emergence of 5 chronic conditions (diabetes, obesity, cognitive impairment, hyperlipidemia, and hypertension) based on four modifiable risk factors representing lifestyle behaviors (diet, exercise habits, tobacco use, alcohol use) and four non-modifiable risk factors, including socio-demographic information (age, gender, education, marital status). The proposed method is tested under different scenarios (e.g., age group, the prior existence of MCC), demonstrating the effective intervention strategies for improving the lifestyle behavioral risk factors to offset MCC evolution.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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