Dual-Teacher: Integrating Intra-domain and Inter-domain Teachers for Annotation-efficient Cardiac Segmentation
The Chinese University of Hong Kong（香港中文大学）；Stanford University（斯坦福大学）；Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）
Medical image annotations are prohibitively time-consuming and expensive to obtain. To alleviate annotation scarcity, many approaches have been developed to efficiently utilize extra information, e.g.,semi-supervised learning further exploring plentiful unlabeled data, domain adaptation including multi-modality learning and unsupervised domain adaptation resorting to the prior knowledge from additional modality. In this paper, we aim to investigate the feasibility of simultaneously leveraging abundant unlabeled data and well-established cross-modality data for annotation-efficient medical image segmentation. To this end, we propose a novel semi-supervised domain adaptation approach, namely Dual-Teacher, where the student model not only learns from labeled target data (e.g., CT), but also explores unlabeled target data and labeled source data (e.g., MR) by two teacher models. Specifically, the student model learns the knowledge of unlabeled target data from intra-domain teacher by encouraging prediction consistency, as well as the shape priors embedded in labeled source data from inter-domain teacher via knowledge distillation. Consequently, the student model can effectively exploit the information from all three data resources and comprehensively integrate them to achieve improved performance. We conduct extensive experiments on MM-WHS 2017 dataset and demonstrate that our approach is able to concurrently utilize unlabeled data and cross-modality data with superior performance, outperforming semi-supervised learning and domain adaptation methods with a large margin.
University of Illinois at Urbana-Champaign（伊利诺伊大学厄巴纳-香槟分校）；United Imaging Intelligence, Cambridge, MA（联影智能（剑桥，马萨诸塞州））；University of Oregon（俄勒冈大学）
Cardiac motion estimation plays a key role in MRI cardiac feature tracking and function assessment such as myocardium strain. In this paper, we propose Motion Pyramid Networks, a novel deep learning-based approach for accurate and efficient cardiac motion estimation. We predict and fuse a pyramid of motion fields from multiple scales of feature representations to generate a more refined motion field. We then use a novel cyclic teacher-student training strategy to make the inference end-to-end and further improve the tracking performance. Our teacher model provides more accurate motion estimati…
The Chinese University of Hong Kong（香港中文大学）；Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）；Stanford University（斯坦福大学）
Annotation scarcity is a long-standing problem in medical image analysis area. To efficiently leverage limited annotations, abundant unlabeled data are additionally exploited in semi-supervised learning, while well-established cross-modality data are investigated in domain adaptation. In this paper, we aim to explore the feasibility of concurrently leveraging both unlabeled data and cross-modality data for annotation-efficient cardiac segmentation. To this end, we propose a cutting-edge semi-supervised domain adaptation framework, namely Dual-Teacher++. Besides directly learning from limited l…
The Chinese University of Hong Kong（香港中文大学）；SenseTime Group Limited（商汤集团有限公司）；Nanyang Technological University（南洋理工大学）
We study the problem of distilling knowledge from a large deep teacher network to a much smaller student network for the task of road marking segmentation. In this work, we explore a novel knowledge distillation (KD) approach that can transfer 'knowledge' on scene structure more effectively from a teacher to a student model. Our method is known as Inter-Region Affinity KD (IntRA-KD). It decomposes a given road scene image into different regions and represents each region as a node in a graph. An inter-region affinity graph is then formed by establishing pairwise relationships between nodes bas…
Enriching Knowledge Distillation with Intra-Class Contrastive Learning
Key Laboratory of New Generation Artificial Intelligence Technology and Its Interdisciplinary Applications (Southeast University), Ministry of Education, China（新一代人工智能技术及其跨学科应用重点实验室（东南大学），教育部，中国）
针对知识蒸馏中教师软标签缺乏类内多样表示的问题，本文提出带 margin loss 的类内对比学习教师训练方法，并通过理论与实验验证其有效性。
Southern University of Science and Technology（南方科技大学）；The Chinese University of Hong Kong（香港中文大学）；Xiamen University（厦门大学）；City University of Hong Kong（香港城市大学）
The amount of medical images for training deep classification models is typically very scarce, making these deep models prone to overfit the training data. Studies showed that knowledge distillation (KD), especially the mean-teacher framework which is more robust to perturbations, can help mitigate the over-fitting effect. However, directly transferring KD from computer vision to medical image classification yields inferior performance as medical images suffer from higher intra-class variance and class imbalance. To address these issues, we propose a novel Categorical Relation-preserving Contr…
University of Science and Technology of China（中国科学技术大学）；JD AI Research（京东人工智能研究院）；City University of Hong Kong（香港城市大学）；Peking University（北京大学）
Rendering synthetic data (e.g., 3D CAD-rendered images) to generate annotations for learning deep models in vision tasks has attracted increasing attention in recent years. However, simply applying the models learnt on synthetic images may lead to high generalization error on real images due to domain shift. To address this issue, recent progress in cross-domain recognition has featured the Mean Teacher, which directly simulates unsupervised domain adaptation as semi-supervised learning. The domain gap is thus naturally bridged with consistency regularization in a teacher-student scheme. In th…
Friedrich-Alexander-Universität Erlangen-Nürnberg（埃尔朗根-纽伦堡弗里德里希-亚历山大大学）；University of Leeds（利兹大学）
Left ventricle segmentation and morphological assessment are essential for improving diagnosis and our understanding of cardiomyopathy, which in turn is imperative for reducing risk of myocardial infarctions in patients. Convolutional neural network (CNN) based methods for cardiac magnetic resonance (CMR) image segmentation rely on supervision with pixel-level annotations, and may not generalize well to images from a different domain. These methods are typically sensitive to variations in imaging protocols and data acquisition. Since annotating multi-sequence CMR images is tedious and subject …
University of Alberta（阿尔伯塔大学）；Cairo University（开罗大学）；Facebook AI Research（Facebook人工智能研究院）
Video object segmentation is an essential task in robot manipulation to facilitate grasping and learning affordances. Incremental learning is important for robotics in unstructured environments, since the total number of objects and their variations can be intractable. Inspired by the children learning process, human robot interaction (HRI) can be utilized to teach robots about the world guided by humans similar to how children learn from a parent or a teacher. A human teacher can show potential objects of interest to the robot, which is able to self adapt to the teaching signal without provid…
Dual Teacher Knowledge Distillation with Domain Alignment for Face Anti-spoofing
Sun Yat-sen University（中山大学）；Tencent YouTu Lab（腾讯优图实验室）；Nanjing University（南京大学）；Harbin Institute of Technology（哈尔滨工业大学）；Southern University of Science and Technology（南方科技大学）
Cardiac left ventricle (LV) quantification is among the most clinically important tasks for identification and diagnosis of cardiac diseases, yet still a challenge due to the high variability of cardiac structure and the complexity of temporal dynamics. Full quantification, i.e., to simultaneously quantify all LV indices including two areas (cavity and myocardium), six regional wall thicknesses (RWT), three LV dimensions, and one cardiac phase, is even more challenging since the uncertain relatedness intra and inter each type of indices may hinder the learning procedure from better convergence…
Pohang University of Science Technology (POSTECH)（浦项科技大学）
Semi-supervised domain adaptation (SSDA) is to adapt a learner to a new domain with only a small set of labeled samples when a large labeled dataset is given on a source domain. In this paper, we propose a pair-based SSDA method that adapts a model to the target domain using self-distillation with sample pairs. Each sample pair is composed of a teacher sample from a labeled dataset (i.e., source or labeled target) and its student sample from an unlabeled dataset (i.e., unlabeled target). Our method generates an assistant feature by transferring an intermediate style between the teacher and the…
Remote Sensing Object Counting with Online Knowledge Learning
Nanjing University of Information Science and Technology（南京信息工程大学）；Nanjing Forestry University（南京林业大学）；Nanjing University of Posts and Telecommunications（南京邮电大学）
SenseTime Research（商汤科技研究院）；The University of Sydney（悉尼大学）；University of Science and Technology of China（中国科学技术大学）
Unlike existing knowledge distillation methods focus on the baseline settings, where the teacher models and training strategies are not that strong and competing as state-of-the-art approaches, this paper presents a method dubbed DIST to distill better from a stronger teacher. We empirically find that the discrepancy of predictions between the student and a stronger teacher may tend to be fairly severer. As a result, the exact match of predictions in KL divergence would disturb the training and make existing methods perform poorly. In this paper, we show that simply preserving the relations be…
University of Science and Technology of China（中国科学技术大学）；The University of Adelaide（阿德莱德大学）；Hefei Comprehensive National Science Center（合肥综合性国家科学中心）；Shanghai Artificial Intelligent Laboratory（上海人工智能实验室）
Recent progresses on self-supervised 3D human action representation learning are largely attributed to contrastive learning. However, in conventional contrastive frameworks, the rich complementarity between different skeleton modalities remains under-explored. Moreover, optimized with distinguishing self-augmented samples, models struggle with numerous similar positive instances in the case of limited action categories. In this work, we tackle the aforementioned problems by introducing a general Inter- and Intra-modal Mutual Distillation (I$^2$MD) framework. In I$^2$MD, we first re-formulate t…
Cross4D-JEPA: Dense Cross-modal Correspondence Distillation for 4D Point Cloud Representation Learning
Nagoya University（名古屋大学）；Northeastern University（东北大学）；KC Machine Learning Lab（KC机器学习实验室）；University of Science, Vietnam National University Ho Chi Minh City（胡志明市越南国立大学理科大学）；University of California, Los Angeles（加州大学洛杉矶分校）
Knowledge distillation (KD) is commonly deemed as an effective model compression technique in which a compact model (student) is trained under the supervision of a larger pretrained model or an ensemble of models (teacher). Various techniques have been proposed since the original formulation, which mimic different aspects of the teacher such as the representation space, decision boundary, or intra-data relationship. Some methods replace the one-way knowledge distillation from a static teacher with collaborative learning between a cohort of students. Despite the recent advances, a clear underst…
School of Electronic Information and Communications, Huazhong University of Science and Technology（华中科技大学电子信息与通信学院）；Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology（华中科技大学同济医学院附属协和医院放射科）；Hubei Province Key Laboratory of Molecular Imaging（湖北省分子影像重点实验室）；HUST-HW Joint Innovation Lab（华中科技大学-华为联合创新实验室）
Cardiac MRI segmentation plays a crucial role in clinical diagnosis for evaluating personalized cardiac performance parameters. Due to the indistinct boundaries and heterogeneous intensity distributions in the cardiac MRI, most existing methods still suffer from two aspects of challenges: inter-class indistinction and intra-class inconsistency. To tackle these two problems, we propose a novel method to exploit the directional feature maps, which can simultaneously strengthen the differences between classes and the similarities within classes. Specifically, we perform cardiac segmentation and l…
Automatic segmentation of myocardial contours and relevant areas like infraction and no-reflow is an important step for the quantitative evaluation of myocardial infarction. In this work, we propose a cascaded convolutional neural network for automatic myocardial infarction segmentation from delayed-enhancement cardiac MRI. We first use a 2D U-Net to focus on the intra-slice information to perform a preliminary segmentation. After that, we use a 3D U-Net to utilize the volumetric spatial information for a subtle segmentation. Our method is evaluated on the MICCAI 2020 EMIDEC challenge dataset …
multimodars: A Rust-powered toolkit for multi-modality cardiac image fusion and registration
Department of Cardiology, Inselspital, Bern University Hospital, University of Bern（伯尔尼大学伯尔尼大学医院 Inselspital 心脏病学系）；Graduate School for Cellular and Biomedical Sciences, University of Bern（伯尔尼大学细胞与生物医学科学研究生院）
SAMba-UNet: SAM2-Mamba UNet for Cardiac MRI in Medical Robotic Perception
University of Electronic Science and Technology of China（电子科技大学）；University of Chinese Academy of Sciences（中国科学院大学）；School of Computer Science, Peking University（北京大学计算机学院）
Nanyang Technological University（南洋理工大学）；National University of Singapore（新加坡国立大学）
While deep models have shown promising performance in medical image segmentation, they heavily rely on a large amount of well-annotated data, which is difficult to access, especially in clinical practice. On the other hand, high-accuracy deep models usually come in large model sizes, limiting their employment in real scenarios. In this work, we propose a novel asymmetric co-teacher framework, ACT-Net, to alleviate the burden on both expensive annotations and computational costs for semi-supervised knowledge distillation. We advance teacher-student learning with a co-teacher network to facilita…
Inter- and intra-uncertainty based feature aggregation model for semi-supervised histopathology image segmentation
Northwestern Polytechnical University（西北工业大学）；La Trobe University（拉筹伯大学）；CSIRO Data61（联邦科学与工业研究组织数据61部）；University of New South Wales（新南威尔士大学）；Shandong University（山东大学）；Tianjin University（天津大学）
University of Leeds（利兹大学）；Leeds Institute for Cardiovascular and Metabolic Medicine（利兹心血管与代谢医学研究所）；KU Leuven（荷语鲁汶大学）；Alan Turing Institute（艾伦·图灵研究所）
Medical image registration is a challenging task involving the estimation of spatial transformations to establish anatomical correspondence between pairs or groups of images. Recently, deep learning-based image registration methods have been widely explored, and demonstrated to enable fast and accurate image registration in a variety of applications. However, most deep learning-based registration methods assume that the deformation fields are smooth and continuous everywhere in the image domain, which is not always true, especially when registering images whose fields of view contain discontin…
University of Edinburgh（爱丁堡大学）；Imperial College London（帝国理工学院）；University of Essex（埃塞克斯大学）
Magnetic Resonance Imaging (MRI) typically recruits multiple sequences (defined here as "modalities"). As each modality is designed to offer different anatomical and functional clinical information, there are evident disparities in the imaging content across modalities. Inter- and intra-modality affine and non-rigid image registration is an essential medical image analysis process in clinical imaging, as for example before imaging biomarkers need to be derived and clinically evaluated across different MRI modalities, time phases and slices. Although commonly needed in real clinical scenarios, …
Friedrich-Alexander-University Erlangen-Nuremberg（弗里德里希-亚历山大-埃尔朗根-纽伦堡大学）；University of Leeds（利兹大学）；CISTIB, Centre for Computational Imaging and Simulation Technologies in Biomedicine（生物医学计算成像与模拟技术中心）；School of Computing（计算机学院）；LICAMM Leeds Institute of Cardiovascular and Metabolic Medicine（利兹心血管与代谢医学研究所）；School of Medicine（医学院）
Deep learning models are sensitive to domain shift phenomena. A model trained on images from one domain cannot generalise well when tested on images from a different domain, despite capturing similar anatomical structures. It is mainly because the data distribution between the two domains is different. Moreover, creating annotation for every new modality is a tedious and time-consuming task, which also suffers from high inter- and intra- observer variability. Unsupervised domain adaptation (UDA) methods intend to reduce the gap between source and target domains by leveraging source domain labe…
Intrapartum Ultrasound Image Segmentation of Pubic Symphysis and Fetal Head Using Dual Student-Teacher Framework with CNN-ViT Collaborative Learning
College of Information Science and Technology, Jinan University（暨南大学信息科学技术学院）；Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Information Technology, Jinan University（暨南大学广东省中医信息技术重点实验室）；Auckland Bioengineering Institute, University of Auckland（奥克兰大学生物工程研究所）；Universitat de Barcelona（巴塞罗那大学）；Institució Catalana de Recerca i Estudis Avançats (ICREA)（加泰罗尼亚研究与高级研究学院（ICREA））
Hannover Medical School（汉诺威医学院）；German Center for Lung Research（德国肺研究中心）；Johannes Gutenberg University（约翰内斯·古腾堡大学）
Background: Cardiac MRI derived biventricular mass and function parameters, such as end-systolic volume (ESV), end-diastolic volume (EDV), ejection fraction (EF), stroke volume (SV), and ventricular mass (VM) are clinically well established. Image segmentation can be challenging and time-consuming, due to the complex anatomy of the human heart. Objectives: This study introduces $ν$-net (/nju:n$\varepsilon$t/) -- a deep learning approach allowing for fully-automated high quality segmentation of right (RV) and left ventricular (LV) endocardium and epicardium for extraction of cardiac function pa…
New York University（纽约大学）；University of Rochester（罗切斯特大学）；Siemens Healthineers（西门子医疗）
Using catheter ablation to treat atrial fibrillation increasingly relies on intracardiac echocardiography (ICE) for an anatomical delineation of the left atrium and the pulmonary veins that enter the atrium. However, it is a challenge to build an automatic contouring algorithm because ICE is noisy and provides only a limited 2D view of the 3D anatomy. This work provides the first automatic solution to segment the left atrium and the pulmonary veins from ICE. In this solution, we demonstrate the benefit of building a cross-modality framework that can leverage a database of diagnostic images to …
RotCAtt-TransUNet++: Novel Deep Neural Network for Sophisticated Cardiac Segmentation
Le Hong Phong High School for the Gifted（黎鸿峰天才高中）；Faculty of Information Technology, University of Science, VNU-HCM（胡志明市国家大学科学学院信息技术系）；Viet Nam National University, Ho Chi Minh City（越南国家大学胡志明市分校）
University of Sherbrooke（舍布鲁克大学）；Univ Lyon（里昂大学）；Université Claude Bernard Lyon 1（里昂第一大学）；UJM-Saint Etienne（圣艾蒂安大学）；CNRS（法国国家科学研究中心）；Inserm（法国国家健康与医学研究院）；Institut Universitaire de France（法国大学研究院）
Convolutional neural networks (CNN) have demonstrated their ability to segment 2D cardiac ultrasound images. However, despite recent successes according to which the intra-observer variability on end-diastole and end-systole images has been reached, CNNs still struggle to leverage temporal information to provide accurate and temporally consistent segmentation maps across the whole cycle. Such consistency is required to accurately describe the cardiac function, a necessary step in diagnosing many cardiovascular diseases. In this paper, we propose a framework to learn the 2D+time apical long-axi…
In nuclear imaging, limited resolution causes partial volume effects (PVEs) that affect image sharpness and quantitative accuracy. Partial volume correction (PVC) methods incorporating high-resolution anatomical information from CT or MRI have been demonstrated to be effective. However, such anatomical-guided methods typically require tedious image registration and segmentation steps. Accurately segmented organ templates are also hard to obtain, particularly in cardiac SPECT imaging, due to the lack of hybrid SPECT/CT scanners with high-end CT and associated motion artifacts. Slight mis-regist…
University of Maryland, College Park（马里兰大学帕克分校）；Shanghai AI Laboratory（上海人工智能实验室）；ShanghaiTech University（上海科技大学）；Shanghai Engineering Research Center of Intelligent Vision and Imaging（上海智能视觉成像工程技术研究中心）
Finding dense semantic correspondence is a fundamental problem in computer vision, which remains challenging in complex scenes due to background clutter, extreme intra-class variation, and a severe lack of ground truth. In this paper, we aim to address the challenge of label sparsity in semantic correspondence by enriching supervision signals from sparse keypoint annotations. To this end, we first propose a teacher-student learning paradigm for generating dense pseudo-labels and then develop two novel strategies for denoising pseudo-labels. In particular, we use spatial priors around the spars…
Scientific Computing and Imaging Institute（科学计算与成像研究所）；University of Utah（犹他大学）；School of Computing（计算学院）
Clinical investigations of anatomy's structural changes over time could greatly benefit from population-level quantification of shape, or spatiotemporal statistic shape modeling (SSM). Such a tool enables characterizing patient organ cycles or disease progression in relation to a cohort of interest. Constructing shape models requires establishing a quantitative shape representation (e.g., corresponding landmarks). Particle-based shape modeling (PSM) is a data-driven SSM approach that captures population-level shape variations by optimizing landmark placement. However, it assumes cross-sectiona…
Comparison of Loss Functions for Robust Deep Learning-based Echocardiography Segmentation when Learning with Partially Labelled Data from Multiple Domains
School of Biomedical Engineering & Imaging Sciences, King’s College London, UK（英国伦敦国王学院生物医学工程与影像科学学院）
Deep Learning-based Prediction of Electrical Arrhythmia Circuits from Cardiac Motion: An In-Silico Study
Cardiovascular Research Institute, University of California, San Francisco（加州大学旧金山分校心血管研究所）；University of California, Berkeley（加州大学伯克利分校）；College of Engineering, Michigan State University（密歇根州立大学工程学院）；Division of Cardiology, University of California, San Francisco（加州大学旧金山分校心脏病学系）
