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arXiv 1706.04397cs.CVstat.ML
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$ν$ -net:广义双心室心脏质量和功能参数的深度学习

$ν$-net: Deep Learning for Generalized Biventricular Cardiac Mass and Function Parameters

Hannover Medical School(汉诺威医学院);German Center for Lung Research(德国肺研究中心);Johannes Gutenberg University(约翰内斯·古腾堡大学)

Hinrich B Winther, Christian Hundt, Bertil Schmidt, Christoph Czerner, Johann Bauersachs, Frank Wacker, Jens Vogel-Claussen

摘要:

背景资料:心脏MRI衍生的双心室质量和功能参数,如收缩末期容积(ESV)、舒张末期容积(EDV)、射血分数(EF)、每搏输出量(SV)和心室质量(VM)在临床上已得到充分确立。由于人类心脏的复杂解剖结构,图像分割可能具有挑战性且耗时。目的:本研究介绍了$ν$ -net(/nju:n $\varepsilon$ t/)-一种深度学习方法,可对右心室(RV)和左心室(LV)内膜和心外膜进行全自动高质量分割,以提取心功能参数。方法:使用253个人工分割的病例集对深度神经网络进行训练。随后,在4个不同的多中心数据集上对该网络进行了评价,总计超过1000例。结果如下:对于LV EF,相应数据集的组内相关系数(ICC)为98、95和80%(95%),RV EF为96和87%(80%)(括号中报告了人类专家ICC)。LV VM ICC为95和94%(84%),RV VM ICC为83和83%(54%)。本研究提出了一个简单的调整程序,允许适应不同的分割哲学。$ν$ -net在骰子系数方面表现出最先进的性能。结论:通过应用深度神经网络进行心脏MRI分割,可以可靠地确定双心室质量和功能参数,特别是在解剖结构复杂的右心室中。通过应用简单的调整程序来适应个体分割样式是可行的,允许处理新数据而无需耗时的额外训练。

英文摘要:

Background: Cardiac MRI derived biventricular mass and function parameters, such as end-systolic volume (ESV), end-diastolic volume (EDV), ejection fraction (EF), stroke volume (SV), and ventricular mass (VM) are clinically well established. Image segmentation can be challenging and time-consuming, due to the complex anatomy of the human heart. Objectives: This study introduces $ν$-net (/nju:n$\varepsilon$t/) -- a deep learning approach allowing for fully-automated high quality segmentation of right (RV) and left ventricular (LV) endocardium and epicardium for extraction of cardiac function parameters. Methods: A set consisting of 253 manually segmented cases has been used to train a deep neural network. Subsequently, the network has been evaluated on 4 different multicenter data sets with a total of over 1000 cases. Results: For LV EF the intraclass correlation coefficient (ICC) is 98, 95, and 80 % (95 %), and for RV EF 96, and 87 % (80 %) on the respective data sets (human expert ICCs reported in parenthesis). The LV VM ICC is 95, and 94 % (84 %), and the RV VM ICC is 83, and 83 % (54 %). This study proposes a simple adjustment procedure, allowing for the adaptation to distinct segmentation philosophies. $ν$-net exhibits state of-the-art performance in terms of dice coefficient. Conclusions: Biventricular mass and function parameters can be determined reliably in high quality by applying a deep neural network for cardiac MRI segmentation, especially in the anatomically complex right ventricle. Adaption to individual segmentation styles by applying a simple adjustment procedure is viable, allowing for the processing of novel data without time-consuming additional training.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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