arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 2004.05399eess.SPcs.LG
收藏

解释用于单导联ECG心律失常分类的深度神经网络

Interpreting Deep Neural Networks for Single-Lead ECG Arrhythmia Classification

Healthcare Technology and Innovation Center (HTIC), Indian Institute of Technology (IIT-M)(印度理工学院马德拉斯分校医疗技术与创新中心);Indian Institute of Technology, Madras (IITM)(印度理工学院马德拉斯分校)

Sricharan Vijayarangan, Balamurali Murugesan, Vignesh R, Preejith SP, Jayaraj Joseph, Mohansankar Sivaprakasam

摘要:

心律失常是心脏疾病中发病率和死亡率的普遍和重要原因。早期诊断是对心律失常患者进行干预的关键。传统上,由心脏病专家通过检查心电图(ECG)来进行诊断。这种诊断方法由于缺乏心脏病专家而受到阻碍。很长一段时间以来,信号处理方法被用于自动心律失常诊断。然而,这些传统的方法需要专业知识,并且无法对广泛的心律失常进行建模。最近,深度学习方法为大规模进行心律失常诊断提供了解决方案。然而,这些模型的黑盒性质禁止心律失常的临床解释。迫切需要将所获得的模型输出与ECG的对应段相关联。为此,提出了两种方法来提供解释的模型。第一种方法是一种新的应用程序的加权类激活地图(梯度CAM)可视化的显着性的CNN模型。在第二种方法中,通过学习LSTM模型的输入删除掩码来导出显着性。可视化是在一个模型上提供的,该模型的能力是通过与基线的比较来建立的。模型显著性的结果不仅提供了对模型预测能力的洞察,而且与心律失常分类的医学文献相一致。

英文摘要:

Cardiac arrhythmia is a prevalent and significant cause of morbidity and mortality among cardiac ailments. Early diagnosis is crucial in providing intervention for patients suffering from cardiac arrhythmia. Traditionally, diagnosis is performed by examination of the Electrocardiogram (ECG) by a cardiologist. This method of diagnosis is hampered by the lack of accessibility to expert cardiologists. For quite some time, signal processing methods had been used to automate arrhythmia diagnosis. However, these traditional methods require expert knowledge and are unable to model a wide range of arrhythmia. Recently, Deep Learning methods have provided solutions to performing arrhythmia diagnosis at scale. However, the black-box nature of these models prohibit clinical interpretation of cardiac arrhythmia. There is a dire need to correlate the obtained model outputs to the corresponding segments of the ECG. To this end, two methods are proposed to provide interpretability to the models. The first method is a novel application of Gradient-weighted Class Activation Map (Grad-CAM) for visualizing the saliency of the CNN model. In the second approach, saliency is derived by learning the input deletion mask for the LSTM model. The visualizations are provided on a model whose competence is established by comparisons against baselines. The results of model saliency not only provide insight into the prediction capability of the model but also aligns with the medical literature for the classification of cardiac arrhythmia.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

↑