Electrocardiograms (ECGs) are an established technique to screen for abnormal cardiac signals. Recent work has established that it is possible to detect arrhythmia directly from the ECG signal using deep learning algorithms. While a few prior approaches with contrastive learning have been successful, the best way to define a positive sample remains an open question. In this project, we investigate several ways to define positive samples, and assess which approach yields the best performance in a downstream task of classifying arrhythmia. We explore spatiotemporal invariances, generic augmentations, demographic similarities, cardiac rhythms, and wave attributes of ECG as potential ways to match positive samples. We then evaluate each strategy with downstream task performance, and find that learned representations invariant to patient identity are powerful in arrhythmia detection. We made our code available in: https://github.com/mandiehyewon/goodviews_ecg.git
Unlocking the diagnostic potential of electrocardiograms through information transfer from cardiac magnetic resonance imaging
School of Computation, Information and Technology, Technical University of Munich（慕尼黑工业大学计算、信息与技术学院）；University of Zurich（苏黎世大学）；School of Medicine, Klinikum Rechts der Isar, Technical University of Munich（慕尼黑工业大学雷赫特-伊萨尔医院医学院）；Imperial College London（伦敦帝国学院）；Munich Center for Machine Learning（慕尼黑机器学习中心）
In recent years, self-supervised learning methods have shown significant improvement for pre-training with unlabeled data and have proven helpful for electrocardiogram signals. However, most previous pre-training methods for electrocardiogram focused on capturing only global contextual representations. This inhibits the models from learning fruitful representation of electrocardiogram, which results in poor performance on downstream tasks. Additionally, they cannot fine-tune the model with an arbitrary set of electrocardiogram leads unless the models were pre-trained on the same set of leads. …
Stanford University（斯坦福大学）；University of California, San Francisco（加利福尼亚大学旧金山分校）；Harvard Medical School（哈佛医学院）
We propose 3KG, a physiologically-inspired contrastive learning approach that generates views using 3D augmentations of the 12-lead electrocardiogram. We evaluate representation quality by fine-tuning a linear layer for the downstream task of 23-class diagnosis on the PhysioNet 2020 challenge training data and find that 3KG achieves a $9.1\%$ increase in mean AUC over the best self-supervised baseline when trained on $1\%$ of labeled data. Our empirical analysis shows that combining spatial and temporal augmentations produces the strongest representations. In addition, we investigate the effec…
Rice University（莱斯大学）；Prudence Medical Technologies Ltd（审慎医疗技术有限公司）
We train an enhanced deep convolutional neural network in order to identify eight cardiac abnormalities from the standard 12-lead electrocardiograms (ECGs) using the dataset of 14000 ECGs. Instead of straightforwardly applying an end-to-end deep learning approach, we find that deep convolutional neural networks enhanced with sophisticated hand crafted features show advantages in reducing generalization errors. Additionally, data preprocessing and augmentation are essential since the distribution of eight cardiac abnormalities are highly biased in the given dataset. Our approach achieves promis…
HeartVoice Medical Technology（心音医疗科技）；University of Science and Technology of China（中国科学技术大学）
Electrocardiogram (ECG) is one of the most convenient and non-invasive tools for monitoring peoples' heart condition, which can use for diagnosing a wide range of heart diseases, including Cardiac Arrhythmia, Acute Coronary Syndrome, et al. However, traditional ECG disease detection models show substantial rates of misdiagnosis due to the limitations of the abilities of extracted features. Recent deep learning methods have shown significant advantages, but they do not provide publicly available services for those who have no training data or computational resources. In this paper, we demonstra…
Zhejiang University（浙江大学）；RealDoctor AI Research Centre（RealDoctor人工智能研究中心）；Shanghai Polytechnic University（上海第二工业大学）；University of Notre Dame（圣母大学）
A large number of people suffer from life-threatening cardiac abnormalities, and electrocardiogram (ECG) analysis is beneficial to determining whether an individual is at risk of such abnormalities. Automatic ECG classification methods, especially the deep learning based ones, have been proposed to detect cardiac abnormalities using ECG records, showing good potential to improve clinical diagnosis and help early prevention of cardiovascular diseases. However, the predictions of the known neural networks still do not satisfactorily meet the needs of clinicians, and this phenomenon suggests that…
Cardiac abnormalities affecting heart rate and rhythm are commonly observed in both healthy and acutely unwell people. Although many of these are benign, they can sometimes indicate a serious health risk. ECG monitors are typically used to detect these events in electrical heart activity, however they are impractical for continuous long-term use. In contrast, current-generation wearables with optical photoplethysmography (PPG) have gained popularity with their low-cost, lack of wires and tiny size. Many cardiac abnormalities such as ectopic beats and AF can manifest as both obvious and subtle …
An Electrocardiogram Multi-task Benchmark with Comprehensive Evaluations and Insightful Findings
Department of Computer Science, Emory University（埃默里大学计算机科学系）；Bakar Computational Health Sciences Institute, University of California, San Francisco（加州大学旧金山分校巴卡计算健康科学研究所）；Center for Data Science, School of Nursing, Emory University（埃默里大学护理学院数据科学中心）；Department of Computer Science, University of Southern California（南加州大学计算机科学系）
The electrocardiogram (ECG) has always been an important biomedical test to diagnose cardiovascular diseases. Current approaches for ECG monitoring are based on body attached electrodes leading to uncomfortable user experience. Therefore, contactless ECG monitoring has drawn tremendous attention, which however remains unsolved. In fact, cardiac electrical-mechanical activities are coupling in a well-coordinated pattern. In this paper, we achieve contactless ECG monitoring by breaking the boundary between the cardiac mechanical and electrical activity. Specifically, we develop a millimeter-wave…
Echo2ECG: Enhancing ECG Representations with Cardiac Morphology from Multi-View Echos
Chair for AI in Healthcare and Medicine, Technical University of Munich (TUM) and TUM University Hospital（人工智能在医疗与医学中的中心，慕尼黑技术大学（TUM）和慕尼黑大学医院）；Department of Cardiology, TUM University Hospital（心血管科，慕尼黑大学医院）；Department of Computing, Imperial College London（计算系，伦敦帝国理工学院）；Munich Center for Machine Learning (MCML)（慕尼黑机器学习中心（MCML））
Angular Gaussian Supervised Contrastive Learning for Long-Tailed Electrocardiogram Arrhythmia Diagnosis
School of Biomedical Engineering, Shanghai Jiao Tong University（上海交通大学生物医学工程学院）；Department of Neurology and Neurological Rehabilitation, Shanghai Yangzhi Rehabilitation Hospital, School of Medicine, Tongji University（同济大学医学院附属上海养志康复医院神经科与神经康复科）
The classification of the electrocardiogram (ECG) signal has a vital impact on identifying heart-related diseases. This can ensure the premature finding of heart disease and the proper selection of the patient's customized treatment. However, the detection of arrhythmia is a challenging task to perform manually. This justifies the necessity of a technique for automatic detection of abnormal heart signals. Therefore, our work is based on the classification of five classes of ECG arrhythmic signals from Physionet's MIT-BIH Arrhythmia Dataset. Artificial Neural Networks (ANN) have demonstrated si…
Ping An Technology（平安科技）；Saw Swee Hock School of Public Health, National University Health System, National University of Singapore（新加坡国立大学国立大学卫生系统苏瑞福公共卫生学院）；Yong Loo Lin School of Medicine, National University Health System, National University of Singapore（新加坡国立大学国立大学卫生系统杨潞龄医学院）；NUS Graduate School for Integrative Sciences & Engineering（新加坡国立大学综合科学与工程研究生院）；Institute of Data Science, National University of Singapore（新加坡国立大学数据科学研究所）
Cardiovascular disease is a major threat to health and one of the primary causes of death globally. The 12-lead ECG is a cheap and commonly accessible tool to identify cardiac abnormalities. Early and accurate diagnosis will allow early treatment and intervention to prevent severe complications of cardiovascular disease. In the PhysioNet/Computing in Cardiology Challenge 2020, our objective is to develop an algorithm that automatically identifies 27 ECG abnormalities from 12-lead ECG recordings.
Texas A&M University（得克萨斯农工大学）；Dell Inc.（戴尔公司）；Heart Artery and Vein Center of Fresno（弗雷斯诺心脏动脉与静脉中心）
Recent introduction of wearable single-lead ECG devices of diverse configurations has caught the intrigue of the medical community. While these devices provide a highly affordable support tool for the caregivers for continuous monitoring and to detect acute conditions, such as arrhythmia, their utility for cardiac diagnostics remains limited. This is because clinical diagnosis of many cardiac pathologies is rooted in gleaning patterns from synchronous 12-lead ECG. If synchronous 12-lead signals of clinical quality can be synthesized from these single-lead devices, it can transform cardiac care…
Institute of Mathematics and Scientific Computing, University of Graz（格拉茨大学数学与科学计算研究所）；BioTechMed-Graz（格拉茨生物科技医学中心）；Medical University of Graz（格拉茨医科大学）；University Hospital Schleswig-Holstein（石勒苏益格-荷尔斯泰因大学医院）；City of Münster Fire Department（明斯特市消防局）；University Hospital Münster（明斯特大学医院）；University of Namibia（纳米比亚大学）
Objective: Exploit accelerometry data for an automatic, reliable, and prompt detection of spontaneous circulation during cardiac arrest, as this is both vital for patient survival and practically challenging. Methods: We developed a machine learning algorithm to automatically predict the circulatory state during cardiopulmonary resuscitation from 4-second-long snippets of accelerometry and electrocardiogram (ECG) data from pauses of chest compressions of real-world defibrillator records. The algorithm was trained based on 422 cases from the German Resuscitation Registry, for which ground truth…
University of Alberta（阿尔伯塔大学）；Canadian VIGOUR Centre（加拿大活力中心）
The 12-lead electrocardiogram (ECG) is a commonly used tool for detecting cardiac abnormalities such as atrial fibrillation, blocks, and irregular complexes. For the PhysioNet/CinC 2020 Challenge, we built an algorithm using gradient boosted tree ensembles fitted on morphology and signal processing features to classify ECG diagnosis. For each lead, we derive features from heart rate variability, PQRST template shape, and the full signal waveform. We join the features of all 12 leads to fit an ensemble of gradient boosting decision trees to predict probabilities of ECG instances belonging to ea…
MEIT: Multimodal Electrocardiogram Instruction Tuning on Large Language Models for Report Generation
The Ohio State University（俄亥俄州立大学）；Imperial College London（伦敦帝国理工学院）；The University of Hong Kong（香港大学）；University of North Carolina at Chapel Hill（北卡罗来纳大学教堂山分校）
Lobachevsky State University of Nizhni Novgorod（下诺夫哥罗德国立洛巴切夫斯基大学）
We propose a method for generating an electrocardiogram (ECG) signal for one cardiac cycle using a variational autoencoder. Using this method we extracted a vector of new 25 features, which in many cases can be interpreted. The generated ECG has quite natural appearance. The low value of the Maximum Mean Discrepancy metric, 0.00383, indicates good quality of ECG generation too. The extracted new features will help to improve the quality of automatic diagnostics of cardiovascular diseases. Also, generating new synthetic ECGs will allow us to solve the issue of the lack of labeled ECG for use th…
The Ohio State University（俄亥俄州立大学）；Wuhan University of Technology（武汉理工大学）
Electrocardiogram (ECG) is a widely used reliable, non-invasive approach for cardiovascular disease diagnosis. With the rapid growth of ECG examinations and the insufficiency of cardiologists, accurate and automatic diagnosis of ECG signals has become a hot research topic. Deep learning methods have demonstrated promising results in predictive healthcare tasks. In this paper, we developed a deep neural network for multi-label classification of cardiac arrhythmias in 12-lead ECG recordings. Experiments on a public 12-lead ECG dataset showed the effectiveness of our method. The proposed model ac…
Probabilistic learning of the Purkinje network from the electrocardiogram
Pontificia Universidad Católica de Chile（智利天主教大学）；Delft University of Technology（代尔夫特理工大学）；Università di Trento（特伦托大学）；Università della Svizzera italiana（瑞士意大利语区大学）
The University of Tennessee（田纳西大学）；University of Oklahoma Health Sciences Center（俄克拉荷马大学健康科学中心）
Cardiac disease is the leading cause of death in the US. Accurate heart disease detection is of critical importance for timely medical treatment to save patients' lives. Routine use of electrocardiogram (ECG) is the most common method for physicians to assess the electrical activities of the heart and detect possible abnormal cardiac conditions. Fully utilizing the ECG data for reliable heart disease detection depends on developing effective analytical models. In this paper, we propose a two-level hierarchical deep learning framework with Generative Adversarial Network (GAN) for automatic diag…
We report Lobachevsky University Database (LUDB) of ECG signals, an open tool for validating ECG delineation algorithms, that is superior to the existing publicly available data bases in several aspects. LUDB contains 200 recordings of 10-second 12-lead electrocardiograms (ECG) from different subjects, representative of a variety of signal morphologies. The boundaries and peaks of QRS complexes and P and T waves are manually annotated by cardiologists for all recordings and independently for each lead, and all records received an expert classification by abnormalities. We present a case study …
Compact Neural Network Algorithm for Electrocardiogram Classification
Centro de Física Aplicada y Tecnología Avanzada（应用物理与先进技术中心）；Instituto de Ciencias Nucleares（核科学研究所）；Instituto Tecnológico y de Estudios Superiores de Monterrey（蒙特雷技术与高等研究学院）
ECGtizer: a fully automated digitizing and signal recovery pipeline for electrocardiograms
IRD（法国发展研究院）；Sorbonne Université（索邦大学）；INSERM（法国国家健康与医学研究院）；Pitié-Salpêtrière University Hospital（皮蒂-萨尔皮特里耶大学医院）；Vanderbilt University Medical Center（范德堡大学医学中心）
Deep Neural Network Architectures for Electrocardiogram Classification: A Comprehensive Evaluation
Independent Researcher（独立研究者）；Department of Materials Engineering, Xi'an Polytechnic University（材料工程系，西安理工大学）；Tandon School of Engineering, New York University（工程学院，纽约大学）；College of Computing, Georgia Institute of Technology（计算学院，佐治亚理工学院）
Many people are currently suffering from heart diseases that can lead to untimely death. The most common heart abnormality is arrhythmia, which is simply irregular beating of the heart. A prediction system for the early intervention and prevention of heart diseases, including cardiovascular diseases (CDVs) and arrhythmia, is important. This paper introduces the classification of electrocardiogram (ECG) heartbeats into normal or abnormal. The approach is based on the combination of swarm optimization algorithms with a modified PannTompkins algorithm (MPTA) and support vector machines (SVMs). Th…
Amplitude-Phase Fusion for Enhanced Electrocardiogram Morphological Analysis
Fudan University（复旦大学）；Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University（复旦大学附属中山医院上海市心血管病研究所）；Zhongshan Hospital, Fudan University（复旦大学附属中山医院）；University of Shanghai for Science and Technology（上海理工大学）
Ingenuity Labs Research Institute（Ingenuity Labs 研究院）
Electrocardiogram (ECG) is the electrical measurement of cardiac activity, whereas Photoplethysmogram (PPG) is the optical measurement of volumetric changes in blood circulation. While both signals are used for heart rate monitoring, from a medical perspective, ECG is more useful as it carries additional cardiac information. Despite many attempts toward incorporating ECG sensing in smartwatches or similar wearable devices for continuous and reliable cardiac monitoring, PPG sensors are the main feasible sensing solution available. In order to tackle this problem, we propose CardioGAN, an advers…
Swiss Center for Electronics and Microtechnology (CSEM SA)（瑞士电子与微技术中心）
ECG heartbeat classification plays a vital role in diagnosis of cardiac arrhythmia. The goal of the Physionet/CinC 2021 challenge was to accurately classify clinical diagnosis based on 12, 6, 4, 3 or 2-lead ECG recordings in order to aid doctors in the diagnoses of different heart conditions. Transformers have had great success in the field of natural language processing in the past years. Our team, CinCSEM, proposes to draw the parallel between text and periodic time series signals by viewing the repeated period as words and the whole signal as a sequence of such words. In this way, the atten…
Objectives: Atrial fibrillation (AF) is a common heart rhythm disorder associated with deadly and debilitating consequences including heart failure, stroke, poor mental health, reduced quality of life and death. Having an automatic system that diagnoses various types of cardiac arrhythmias would assist cardiologists to initiate appropriate preventive measures and to improve the analysis of cardiac disease. To this end, this paper introduces a new approach to detect and classify automatically cardiac arrhythmias in electrocardiograms (ECG) recordings. Methods: The proposed approach used a combi…
Institute of Data Science, National University of Singapore（新加坡国立大学数据科学研究所）；School of Computing, National University of Singapore（新加坡国立大学计算学院）；National University of Singapore（新加坡国立大学）
Atrial Fibrillation (AF) is a common cardiac arrhythmia affecting a large number of people around the world. If left undetected, it will develop into chronic disability or even early mortality. However, patients who have this problem can barely feel its presence, especially in its early stage. A non-invasive, automatic, and effective detection method is therefore needed to help early detection so that medical intervention can be implemented in time to prevent its progression. Electrocardiogram (ECG), which records the electrical activities of the heart, has been widely used for detecting the p…
With tens of thousands of electrocardiogram (ECG) records processed by mobile cardiac event recorders every day, heart rhythm classification algorithms are an important tool for the continuous monitoring of patients at risk. We utilise an annotated dataset of 12,186 single-lead ECG recordings to build a diverse ensemble of recurrent neural networks (RNNs) that is able to distinguish between normal sinus rhythms, atrial fibrillation, other types of arrhythmia and signals that are too noisy to interpret. In order to ease learning over the temporal dimension, we introduce a novel task formulation…
Healthcare Technology and Innovation Center (HTIC), Indian Institute of Technology (IIT-M)（印度理工学院马德拉斯分校医疗技术与创新中心）；Indian Institute of Technology, Madras (IITM)（印度理工学院马德拉斯分校）
Cardiac arrhythmia is a prevalent and significant cause of morbidity and mortality among cardiac ailments. Early diagnosis is crucial in providing intervention for patients suffering from cardiac arrhythmia. Traditionally, diagnosis is performed by examination of the Electrocardiogram (ECG) by a cardiologist. This method of diagnosis is hampered by the lack of accessibility to expert cardiologists. For quite some time, signal processing methods had been used to automate arrhythmia diagnosis. However, these traditional methods require expert knowledge and are unable to model a wide range of arr…
Low-power sensing technologies, such as wearables, have emerged in the healthcare domain since they enable continuous and non-invasive monitoring of physiological signals. In order to endow such devices with clinical value, classical signal processing has encountered numerous challenges. However, data-driven methods, such as machine learning, offer attractive accuracies at the expense of being resource and memory demanding. In this paper, we focus on the inference of neural networks running in microcontrollers and low-power processors which wearable sensors and devices are generally equipped w…
School of Computer Science and Technology, Harbin Institute of Technology (HIT)（哈尔滨工业大学计算机科学与技术学院）；School of Physics and Astronomy, The University of Manchester（曼彻斯特大学物理与天文学院）；SPACEnter Space Science and Technology Institute（SPACEnter空间科学与技术研究院）；Northeastern University（东北大学）；Beijing Electric Power Hospital（北京电力医院）
Heart disease is one of the most common diseases causing morbidity and mortality. Electrocardiogram (ECG) has been widely used for diagnosing heart diseases for its simplicity and non-invasive property. Automatic ECG analyzing technologies are expected to reduce human working load and increase diagnostic efficacy. However, there are still some challenges to be addressed for achieving this goal. In this study, we develop an algorithm to identify multiple abnormalities from 12-lead ECG recordings. In the algorithm pipeline, several preprocessing methods are firstly applied on the ECG data for de…
