arXiv 2002.059602020-02physics.opticsquant-ph

显微镜与未检测到的光子在中红外

Microscopy with undetected photons in the mid-infrared

Inna Kviatkovsky, Helen M. Chrzanowski, Ellen G. Avery, Hendrik Bartolomaeus, Sven Ramelow

备注：: back-to-back submission with arXiv:2002.05956, Anna V. Paterova, Sivakumar M. Maniam, Hongzhi Yang, Gianluca Grenci, and Leonid A. Krivitsky, "Hyperspectral Infrared Microscopy With Visible Light "

摘要：

由于其独特的（生物）化学特异性的能力，显微镜与中红外照明具有巨大的希望，为广泛的生物医学和工业应用。然而，主要的限制仍然是检测;目前的中红外检测技术往往将低劣的技术能力与高昂的成本结合起来。这导致了将探测波长转换到可见光范围的方法，在可见光范围内，可以使用非常优越的硅基相机技术。在这里，我们通过实验展示了纠缠光的非线性干涉术如何为中红外显微镜提供强大的工具，同时只需要使用标准CMOS相机进行近红外检测。在这个原理验证实现中，我们展示了强度成像overa覆盖3.4-4.3um的宽波长范围，并展示了包含650个解析元素的图像的空间分辨率为35 um。此外，我们证明了我们的技术是适合的目的，在中红外获取生物组织样品的显微图像。这些结果打开了一个新的视角，量子成像技术在生命科学中的潜在相关性。

英文摘要：

Owing to its capacity for unique (bio)-chemical specificity, microscopy withmid-IR illumination holds tremendous promise for a wide range of biomedical and industrial applications. The primary limitation, however, remains detection; with current mid-IR detection technology often marrying inferior technical capabilities with prohibitive costs. This has lead to approaches that shift detection towavelengths into the visible regime, where vastly superior silicon-based cameratechnology is available. Here, we experimentally show how nonlinear interferometry with entangled light can provide a powerful tool for mid-IR microscopy, while only requiring near-infrared detection with a standard CMOS camera. In this proof-of-principle implementation, we demonstrate intensity imaging overa broad wavelength range covering 3.4-4.3um and demonstrate a spatial resolution of 35um for images containing 650 resolved elements. Moreover, we demonstrate our technique is fit for purpose, acquiring microscopic images of biological tissue samples in the mid-IR. These results open a new perspective for potential relevance of quantum imaging techniques in the life sciences.

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