Traditionally, the least squares regression is mainly concerned with studying the effects of individual predictor variables, but strongly correlated variables generate multicollinearity which makes it difficult to study their effects. Existing methods for handling multicollinearity such as ridge regression are complicated. To resolve the multicollinearity issue without abandoning the simple least squares regression, for situations where predictor variables are in groups with strong within-group correlations but weak between-group correlations, we propose to study the effects of the groups with a group approach to the least squares regression. Using an all positive correlations arrangement of the strongly correlated variables, we first characterize group effects that are meaningful and can be accurately estimated. We then present the group approach with numerical examples and demonstrate its advantages over existing methods for handling multicollinearity. We also address a common misconception about prediction accuracy of the least squares estimated model and discuss through an example similar group effects in generalized linear models.
Whereas translating the coding of predictor variables does not change the fit of a polynomial least squares regression, penalized polynomial regressions are potentially affected. A result on which terms can be penalized to maintain the invariance to translations of the coding has earlier been published. A generalization of a corresponding proposition, which requires a more precise mathematical framework, is presented in this short note.
Groupwise Predictor Envelope Models for Multivariate Linear Regression
The Institute of Statistical Mathematics（统计数学研究所）；Graduate School of Mathematics, Kyushu University（九州大学大学院数理学府）；Faculty of Mathematics, Kyushu University（九州大学数学部）
This paper considers linear model selection when the response is vector-valued and the predictors are randomly observed. We propose a new approach that decouples statistical inference from the selection step in a "post-inference model summarization" strategy. We study the impact of predictor uncertainty on the model selection procedure. The method is demonstrated through an application to asset pricing.
Deciding which predictors to use plays an integral role in deriving statistical models in a wide range of applications. Motivated by the challenges of predicting events across a telecommunications network, we propose a semi-automated, joint model-fitting and predictor selection procedure for linear regression models. Our approach can model and account for serial correlation in the regression residuals, produces sparse and interpretable models and can be used to jointly select models for a group of related responses. This is achieved through fitting linear models under constraints on the number…
In prediction problems with more predictors than observations, it can sometimes be helpful to use a joint probability model, $π(Y,X)$, rather than a purely conditional model, $π(Y \mid X)$, where $Y$ is a scalar response variable and $X$ is a vector of predictors. This approach is motivated by the fact that in many situations the marginal predictor distribution $π(X)$ can provide useful information about the parameter values governing the conditional regression. However, under very mild misspecification, this marginal distribution can also lead conditional inferences astray. Here, we explore t…
A regression model is proposed for the analysis of an ordinal response variable depending on a set of multiple covariates containing ordinal and potentially other variables. The proportional odds model (McCullagh (1980)) is used for the ordinal response, and constrained maximum likelihood estimation is used to account for the ordinality of covariates. Ordinal predictors are coded by dummy variables. The parameters associated to the categories of the ordinal predictor(s) are constrained, enforcing them to be monotonic (isotonic or antitonic). A decision rule is introduced for classifying the or…
We propose a ranking and selection procedure to prioritize relevant predictors and control false discovery proportion (FDP) of variable selection. Our procedure utilizes a new ranking method built upon the de-sparsified Lasso estimator. We show that the new ranking method achieves the optimal order of minimum non-zero effects in ranking relevant predictors ahead of irrelevant ones. Adopting the new ranking method, we develop a variable selection procedure to asymptotically control FDP at a user-specified level. We show that our procedure can consistently estimate the FDP of variable selection …
Compositional data are common in many fields, both as outcomes and predictor variables. The inventory of models for the case when both the outcome and predictor variables are compositional is limited and the existing models are difficult to interpret, due to their use of complex log-ratio transformations. We develop a transformation-free linear regression model where the expected value of the compositional outcome is expressed as a single Markov transition from the compositional predictor. Our approach is based on generalized method of moments thereby not requiring complete specification of da…
Dimension reduction is an important tool for analyzing high-dimensional data. The predictor envelope is a method of dimension reduction for regression that assumes certain linear combinations of the predictors are immaterial to the regression. The method can result in substantial gains in estimation efficiency and prediction accuracy over traditional maximum likelihood and least squares estimates. While predictor envelopes have been developed and studied for independent data, no work has been done adapting predictor envelopes to spatial data. In this work, the predictor envelope is adapted to …
Classical finite mixture regression is useful for modeling the relationship between scalar predictors and scalar responses arising from subpopulations defined by the differing associations between those predictors and responses. Here we extend the classical finite mixture regression model to incorporate functional predictors by taking a wavelet-based approach in which we represent both the functional predictors and the component-specific coefficient functions in terms of an appropriate wavelet basis. In the wavelet representation of the model, the coefficients corresponding to the functional c…
We propose a principal components regression method based on maximizing a joint pseudo-likelihood for responses and predictors. Our method uses both responses and predictors to select linear combinations of the predictors relevant for the regression, thereby addressing an oft-cited deficiency of conventional principal components regression. The proposed estimator is shown to be consistent in a wide range of settings, including ones with non-normal and dependent observations; conditions on the first and second moments suffice if the number of predictors ($p$) is fixed and the number of observat…
Heavy-tailed continuous shrinkage priors, such as the horseshoe prior, are widely used for sparse estimation problems. However, there is limited work extending these priors to predictors with grouping structures. Of particular interest in this article, is regression coefficient estimation where pockets of high collinearity in the covariate space are contained within known covariate groupings. To assuage variance inflation due to multicollinearity we propose the group inverse-gamma gamma (GIGG) prior, a heavy-tailed prior that can trade-off between local and group shrinkage in a data adaptive f…
In this work, we introduce a modified (rescaled) likelihood for imbalanced logistic regression. This new approach makes easier the use of exponential priors and the computation of lasso regularization path. Precisely, we study a limiting behavior for which class imbalance is artificially increased by replication of the majority class observations. If some strong overlap conditions are satisfied, the maximum likelihood estimate converges towards a finite value close to the initial one (intercept excluded) as shown by simulations with binary predictors. This solution corresponds to the extremum …
We provide a remedy for two concerns that have dogged the use of principal components in regression: (i) principal components are computed from the predictors alone and do not make apparent use of the response, and (ii) principal components are not invariant or equivariant under full rank linear transformation of the predictors. The development begins with principal fitted components [Cook, R. D. (2007). Fisher lecture: Dimension reduction in regression (with discussion). Statist. Sci. 22 1--26] and uses normal models for the inverse regression of the predictors on the response to gain reducti…
This article proposes a Bayesian approach to regression with a continuous scalar response and an undirected network predictor. Undirected network predictors are often expressed in terms of symmetric adjacency matrices, with rows and columns of the matrix representing the nodes, and zero entries signifying no association between two corresponding nodes. Network predictor matrices are typically vectorized prior to any analysis, thus failing to account for the important structural information in the network. This results in poor inferential and predictive performance in presence of small sample s…
In a longitudinal study, measures of key variables might be incomplete or partially recorded due to drop-out, loss to follow-up, or early termination of the study occurring before the advent of the event of interest. In this paper, we focus primarily on the implementation of a regression model with a randomly censored predictor. We examine, particularly, the use of inverse probability weighting methods in a generalized linear model (GLM), when the predictor of interest is right-censored, to adjust for censoring. To improve the performance of the complete-case analysis and prevent selection bia…
We develop a modeling framework for dynamic function-on-scalars regression, in which a time series of functional data is regressed on a time series of scalar predictors. The regression coefficient function for each predictor is allowed to be dynamic, which is essential for applications where the association between predictors and a (functional) response is time-varying. For greater modeling flexibility, we design a nonparametric reduced-rank functional data model with an unknown functional basis expansion, which is data-adaptive and, unlike most existing methods, modeled as unknown for appropr…
In genomic studies, identifying biomarkers associated with a variable of interest is a major concern in biomedical research. Regularized approaches are classically used to perform variable selection in high-dimensional linear models. However, these methods can fail in highly correlated settings. We propose a novel variable selection approach called WLasso, taking these correlations into account. It consists in rewriting the initial high-dimensional linear model to remove the correlation between the biomarkers (predictors) and in applying the generalized Lasso criterion. The performance of WLas…
The paper proposes to analyze epidemiological data using regression models which enable subject-matter (epidemiological) interpretation of such data whether with uncorrelated or correlated predictors. To this end, response functions should include not only terms linear in predictors but also higher order ones (e.g. quadratic and cross terms). For epidemiological interpretation of a regression model, the suggestion is to construct conditional functions derived from the general regression function with the values of all predictor variables held fixed excepting one predictor. Unlike the conventio…
In a recent paper Noh et al. (2013) proposed a new semiparametric estimate of a regression function with a multivariate predictor, which is based on a specification of the dependence structure between the predictor and the response by means of a parametric copula. This paper investigates the effect which occurs under misspecification of the parametric model. We demonstrate that even for a one or two dimensional predictor the error caused by a \wrong" specification of the parametric family is rather severe, if the regression is not monotone in one of the components of the predictor. Moreover, w…
Functional variables are often used as predictors in regression problems. A commonly-used parametric approach, called {\it scalar-on-function regression}, uses the $\ltwo$ inner product to map functional predictors into scalar responses. This method can perform poorly when predictor functions contain undesired phase variability, causing phases to have disproportionately large influence on the response variable. One past solution has been to perform phase-amplitude separation (as a pre-processing step) and then use only the amplitudes in the regression model. Here we propose a more integrated a…
The $α$--regression for compositional data: a unified framework for standard, temporal and spatial regression models including compositional predictors
University of Crete（克里特大学）；King Saud bin Abdulaziz University for Health Sciences（国王萨勒曼·本·阿卜杜勒阿齐兹健康科学大学）；King Abdullah International Medical Research Center（阿卜杜拉国王国际医学研究中心）；Northern Border University（北部边境大学）
The research described in this paper is motivated by model checking for parametric single-index models with diverging number of predictors. To construct a test statistic, we first study the asymptotic property of the estimators of involved parameters of interest under the null and alternative hypothesis when the dimension is divergent to infinity as the sample size goes to infinity. For the testing problem, we study an adaptive-to-model residual-marked empirical process as the basis for constructing a test statistic. By modifying the approach in the literature to suit the diverging dimension s…
Generalized linear and additive models are very efficient regression tools but the selection of relevant terms becomes difficult if higher order interactions are needed. In contrast, tree-based methods also known as recursive partitioning are explicitly designed to model a specific form of interaction but with their focus on interaction tend to neglect the main effects. The method proposed here focusses on the main effects of categorical predictors by using tree type methods to obtain clusters. In particular when the predictor has many categories one wants to know which of the categories have …
Functional linear regression is an important topic in functional data analysis. It is commonly assumed that samples of the functional predictor are independent realizations of an underlying stochastic process, and are observed over a grid of points contaminated by i.i.d. measurement errors. In practice, however, the dynamical dependence across different curves may exist and the parametric assumption on the error covariance structure could be unrealistic. In this paper, we consider functional linear regression with serially dependent observations of the functional predictor, when the contaminat…
Scientific theories can often be formulated using equality and order constraints on the relative effects in a linear regression model. For example, it may be expected that the effect of the first predictor is larger than the effect of the second predictor, and the second predictor is expected to be larger than the third predictor. The goal is then to test such expectations against competing scientific expectations or theories. In this paper a simple default Bayes factor test is proposed for testing multiple hypotheses with equality and order constraints on the effects of interest. The proposed…
Many important modeling tasks in linear regression, including variable selection (in which slopes of some predictors are set equal to zero) and simplified models based on sums or differences of predictors (in which slopes of those predictors are set equal to each other, or the negative of each other, respectively), can be viewed as being based on imposing linear restrictions on regression parameters. In this paper, we discuss how such models can be compared using information criteria designed to estimate predictive measures like squared error and Kullback-Leibler (KL) discrepancy, in the prese…
In regression models, predictor variables with inherent ordering, such as tumor staging ranging and ECOG performance status, are commonly seen in medical settings. Statistically, it may be difficult to determine the functional form of an ordinal predictor variable. Often, such a variable is dichotomized based on whether it is above or below a certain cutoff. Other methods conveniently treat the ordinal predictor as a continuous variable and assume a linear relationship with the outcome. However, arbitrarily choosing a method may lead to inaccurate inference and treatment. In this paper, we pro…
A variable group Y is assumed to depend upon R thematic variable groups X 1, >..., X R . We assume that components in Y depend linearly upon components in the Xr's. In this work, we propose a multiple covariance criterion which extends that of PLS regression to this multiple predictor groups situation. On this criterion, we build a PLS-type exploratory method - Structural Equation Exploratory Regression (SEER) - that allows to simultaneously perform dimension reduction in groups and investigate the linear model of the components. SEER uses the multidimensional structure of each group. An appli…
In the regression setting, dimension reduction allows for complicated regression structures to be detected via visualization in a low-dimension framework. However, some popular dimension reduction methodologies fail to achieve this aim when faced with a problem often referred to as symmetric dependency. In this paper we show how vastly superior results can be achieved when carrying out response and predictor transformations for methods such as least squares and Sliced Inverse Regression. These transformations are simple to implement and utilize estimates from other dimension reduction methods …
In the functional linear regression model, many methods have been proposed and studied to estimate the slope function while the functional predictor was observed in the entire domain. However, works on functional linear regression models with partially observed trajectories have received less attention. In this paper, to fill the literature gap we consider the scenario where individual functional predictor may be observed only on part of the domain. Depending on whether measurement error is presented in functional predictors, two methods are developed, one is based on linear functionals of the…
Statistical methods relating tensor predictors to scalar outcomes in a regression model generally vectorize the tensor predictor and estimate the coefficients of its entries employing some form of regularization, use summaries of the tensor covariate, or use a low dimensional approximation of the coefficient tensor. However, low rank approximations of the coefficient tensor can suffer if the true rank is not small. We propose a tensor regression framework which assumes a soft version of the parallel factors (PARAFAC) approximation. In contrast to classic PARAFAC, where each entry of the coeffi…
The Akaike information criterion (AIC) is commonly used to select a logistic regression model for optimal prediction of a binary response by a specified family of models. It however lacks a convincing method of prescribing a proper family of models using the desired predictors and their interaction effects. For an alternative approach to model selection, we propose a direct selection scheme which first identifies the indispensable regressors as main-effect predictors, then examines significant interaction effects between the selected predictors such that a logistic model is constructed. The tw…
The development and use of dimension reduction methods is prevalent in modern statistical literature. This paper reviews a class of dimension reduction techniques which aim to simultaneously select relevant predictors and find clusters within them which share a common effect on the response. Such methods have been shown to have superior performance relative to OLS estimates and the lasso [Tibshirani, 1996] especially when multicollinearity in the predictors is present. Their applications, which include genetics, epidemiology, and fMRI studies, are also discussed.
This paper suggests parametrically transformed nested error regression models (TNERM), which transform the data flexibly to follow the normal linear mixed regression. We provide a procedure for estimating consistently the parameters of the proposed model and a predictor based on the consistent estimators. Then, in order to calibrate uncertainty of the transformed empirical best linear unbiased predictor, we derive prediction intervals with second-order accuracy based on the parametric bootstrap method. The proposed methods are investigated through simulation and empirical studies.
Local Fréchet Regression with Riemannian Predictors
The Institute for Data Innovation in Science, Seoul National University（首尔大学数据创新科学研究所）；Department of Statistics and School of Transdisciplinary Innovations, Seoul National University（首尔大学统计系与跨学科创新学院）
