Training of neural networks for automated diagnosis of pigmented skin lesions is hampered by the small size and lack of diversity of available datasets of dermatoscopic images. We tackle this problem by releasing the HAM10000 ("Human Against Machine with 10000 training images") dataset. We collected dermatoscopic images from different populations acquired and stored by different modalities. Given this diversity we had to apply different acquisition and cleaning methods and developed semi-automatic workflows utilizing specifically trained neural networks. The final dataset consists of 10015 dermatoscopic images which are released as a training set for academic machine learning purposes and are publicly available through the ISIC archive. This benchmark dataset can be used for machine learning and for comparisons with human experts. Cases include a representative collection of all important diagnostic categories in the realm of pigmented lesions. More than 50% of lesions have been confirmed by pathology, while the ground truth for the rest of the cases was either follow-up, expert consensus, or confirmation by in-vivo confocal microscopy.
DERM12345: A Large, Multisource Dermatoscopic Skin Lesion Dataset with 38 Subclasses
Imperial College London（帝国理工学院）；The University of Health Sciences（健康科学大学）；Haydarpasa Numune Research and Training Hospital（海达尔帕夏努穆内研究与培训医院）；Istinye University（伊斯坦布尔伊斯坦尼耶大学）；Liv Hospital Vadistanbul（瓦迪斯坦布尔丽芙医院）
Medical University of Vienna（维也纳医科大学）；TissueGnostics GmbH（TissueGnostics有限公司）
Malignant melanoma (MM) is one of the deadliest types of skin cancer. Analysing dermatoscopic images plays an important role in the early detection of MM and other pigmented skin lesions. Among different computer-based methods, deep learning-based approaches and in particular convolutional neural networks have shown excellent classification and segmentation performances for dermatoscopic skin lesion images. These models can be trained end-to-end without requiring any hand-crafted features. However, the effect of using lesion segmentation information on classification performance has remained a…
Skin cancer is the most common type of cancer. Specifically, melanoma is the cause of 75% of skin cancer deaths, although it is the least common skin cancer. Better detection of melanoma could have a positive impact on millions of people. The ISIC archive contains the largest publicly available collection of dermatoscopic images of skin lesions. In this research, we investigate the efficacy of applying advanced deep learning techniques in computer vision to identify melanoma in images of skin lesions. Through reviewing previous methods, including pre-trained models, deep-learning classifiers, …
Hospital Clínic Barcelona, Universitat de Barcelona, IDIBAPS（巴塞罗那临床医院，巴塞罗那大学，IDIBAPS）；IBM Research AI, T J Watson Research Center（IBM研究AI，T J Watson研究中心）；Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center（医学部皮肤科，纪念斯隆-凯特琳癌症中心）；Kitware；Signal Theory and Communications, Universitat Politècnica de Catalunya（信号理论与通信，加泰罗尼亚理工大学）；Melanoma Unit, Dermatology Department, Hospital Clínic Barcelona, Universitat de Barcelona, IDIBAPS（黑素瘤科，皮肤科，巴塞罗那临床医院，巴塞罗那大学，IDIBAPS）
This article summarizes the BCN20000 dataset, composed of 19424 dermoscopic images of skin lesions captured from 2010 to 2016 in the facilities of the Hospital Clínic in Barcelona. With this dataset, we aim to study the problem of unconstrained classification of dermoscopic images of skin cancer, including lesions found in hard-to-diagnose locations (nails and mucosa), large lesions which do not fit in the aperture of the dermoscopy device, and hypo-pigmented lesions. The BCN20000 will be provided to the participants of the ISIC Challenge 2019, where they will be asked to train algorithms to c…
kin cancer is considered one of the most common type of cancer in several countries. Due to the difficulty and subjectivity in the clinical diagnosis of skin lesions, Computer-Aided Diagnosis systems are being developed for assist experts to perform more reliable diagnosis. The clinical analysis and diagnosis of skin lesions relies not only on the visual information but also on the context information provided by the patient. This work addresses the problem of pigmented skin lesions detection from smartphones captured images. In addition to the features extracted from images, patient context i…
Department of CS & IT, SUIT Peshawar（白沙瓦SUIT计算机科学与信息技术系）
Skin lesion segmentation can be rather a challenging task owing to the presence of artifacts, low contrast between lesion and boundary, color variegation, fuzzy skin lesion borders and heterogeneous background in dermoscopy images. In this paper, we propose a simple yet effective saliency-based approach derived in the frequency and spatial domain to detect pigmented skin lesion. Two color models are utilized for the construction of these maps. We suggest a different metric for each color model to design map in the spatial domain via color features. The map in the frequency domain is generated …
Boosting Dermatoscopic Lesion Segmentation via Diffusion Models with Visual and Textual Prompts
Shanghai Artificial Intelligence Lab（上海人工智能实验室）；Johns Hopkins University（约翰斯·霍普金斯大学）；University of California Santa Cruz（加利福尼亚大学圣克鲁兹分校）；West China Biomedical Big Data Center, Sichuan University West China Hospital（四川大学华西医院华西生物医学大数据中心）
Medical Image Analysis Lab, School of Computing Science（计算科学学院医学图像分析实验室）；Simon Fraser University（西蒙弗雷泽大学）
We present an automated approach to detect and longitudinally track skin lesions on 3D total-body skin surface scans. The acquired 3D mesh of the subject is unwrapped to a 2D texture image, where a trained objected detection model, Faster R-CNN, localizes the lesions within the 2D domain. These detected skin lesions are mapped back to the 3D surface of the subject and, for subjects imaged multiple times, we construct a graph-based matching procedure to longitudinally track lesions that considers the anatomical correspondences among pairs of meshes and the geodesic proximity of corresponding le…
Escola Politècnica Superior, Universitat de Girona（赫罗纳大学高等理工学院）
Fully automatic detection of skin lesions in dermatoscopic images can facilitate early diagnosis and repression of malignant melanoma and non-melanoma skin cancer. Although convolutional neural networks are a powerful solution, they are limited by the illumination spectrum of annotated dermatoscopic screening images, where color is an important discriminative feature. In this paper, we propose an adaptive color augmentation technique to amplify data expression and model performance, while regulating color difference and saturation to minimize the risks of using synthetic data. Through deep vis…
Fusion of Foundation and Vision Transformer Model Features for Dermatoscopic Image Classification
Research Center for Medical Image Analysis and Artificial Intelligence, Department of Medicine, Faculty of Medicine and Dentistry, Danube Private University（医学影像分析与人工智能研究中心、医学部、医学与牙科学院、多瑙私人大学）；Department of Research and Development, TissueGnostics GmbH（研发部、TissueGnostics GmbH）
Tarbiat Modares University（塔比亚特莫达雷斯大学）；Islamic Azad University Science and Research Branch（伊斯兰阿扎德大学科学与研究分校）
At present, cancer is one of the most important health issues in the world. Because early detection and appropriate treatment in cancer are very effective in the recovery and survival of patients, image processing as a diagnostic tool can help doctors to diagnose in the first recognition of cancer. One of the most important steps in diagnosing a skin lesion is to automatically detect the border of the skin image because the accuracy of the next steps depends on it. If these subtleties are identified, they can have a great impact on the diagnosis of the disease. Therefore, there is a good oppor…
University of Notre Dame（圣母大学）；Nanjing University of Science and Technology（南京理工大学）；Qingdao Women and Children’s Hospital of Qingdao University（青岛大学附属青岛妇女儿童医院）；University of Connecticut（康涅狄格大学）
Automatic classification of pigmented, non-pigmented, and depigmented non-melanocytic skin lesions have garnered lots of attention in recent years. However, imaging variations in skin texture, lesion shape, depigmentation contrast, lighting condition, etc. hinder robust feature extraction, affecting classification accuracy. In this paper, we propose a new deep neural network that exploits input data for robust feature extraction. Specifically, we analyze the convolutional network's behavior (field-of-view) to find the location of deep supervision for improved feature extraction. To achieve thi…
Background: Dermoscopy is one of the major imaging modalities used in the diagnosis of melanoma and other pigmented skin lesions. Due to the difficulty and subjectivity of human interpretation, automated analysis of dermoscopy images has become an important research area. Border detection is often the first step in this analysis. Methods: In this article, we present an approximate lesion localization method that serves as a preprocessing step for detecting borders in dermoscopy images. In this method, first the black frame around the image is removed using an iterative algorithm. The approxima…
Background: Dermoscopy is one of the major imaging modalities used in the diagnosis of melanoma and other pigmented skin lesions. Due to the difficulty and subjectivity of human interpretation, computerized analysis of dermoscopy images has become an important research area. One of the most important steps in dermoscopy image analysis is the automated detection of lesion borders. Methods: In this article, we present a systematic overview of the recent border detection methods in the literature paying particular attention to computational issues and evaluation aspects. Conclusion: Common proble…
Louisiana State Univ.（路易斯安那州立大学）；Univ. of Electronic Science and Technology of China（电子科技大学）；Univ. of Illinois（伊利诺伊大学）；Hosei Univ.（法政大学）；Loughborough Univ.（拉夫堡大学）
Dermoscopy is one of the major imaging modalities used in the diagnosis of melanoma and other pigmented skin lesions. Due to the difficulty and subjectivity of human interpretation, automated analysis of dermoscopy images has become an important research area. Border detection is often the first step in this analysis. In many cases, the lesion can be roughly separated from the background skin using a thresholding method applied to the blue channel. However, no single thresholding method appears to be robust enough to successfully handle the wide variety of dermoscopy images encountered in clin…
Escuela Politécnica Superior, Universidad Autónoma de Madrid（马德里自治大学高等理工学院）
State-of-the-art deep learning approaches for skin lesion recognition often require pretraining on larger and more varied datasets, to overcome the generalization limitations derived from the reduced size of the skin lesion imaging datasets. ImageNet is often used as the pretraining dataset, but its transferring potential is hindered by the domain gap between the source dataset and the target dermatoscopic scenario. In this work, we introduce a novel pretraining approach that sequentially trains a series of Self-Supervised Learning pretext tasks and only requires the unlabeled skin lesion imag…
Background: Dermoscopy is one of the major imaging modalities used in the diagnosis of melanoma and other pigmented skin lesions. Due to the difficulty and subjectivity of human interpretation, dermoscopy image analysis has become an important research area. One of the most important steps in dermoscopy image analysis is the automated detection of lesion borders. Although numerous methods have been developed for the detection of lesion borders, very few studies were comprehensive in the evaluation of their results. Methods: In this paper, we evaluate five recent border detection methods on a s…
Background: Automated classification of medical images through neural networks can reach high accuracy rates but lack interpretability. Objectives: To compare the diagnostic accuracy obtained by using content based image retrieval (CBIR) to retrieve visually similar dermatoscopic images with corresponding disease labels against predictions made by a neural network. Methods: A neural network was trained to predict disease classes on dermatoscopic images from three retrospectively collected image datasets containing 888, 2750 and 16691 images respectively. Diagnosis predictions were made based o…
Medical University of Vienna（维也纳医科大学）；Loughborough University（拉夫堡大学）；KTH Royal Institute of Technology（瑞典皇家理工学院）；TissueGnostics GmbH（TissueGnostics有限公司）
Skin cancer is among the most common cancer types. Dermoscopic image analysis improves the diagnostic accuracy for detection of malignant melanoma and other pigmented skin lesions when compared to unaided visual inspection. Hence, computer-based methods to support medical experts in the diagnostic procedure are of great interest. Fine-tuning pre-trained convolutional neural networks (CNNs) has been shown to work well for skin lesion classification. Pre-trained CNNs are usually trained with natural images of a fixed image size which is typically significantly smaller than captured skin lesion i…
Kasetsart University Sriracha Campus（农业大学是拉差校区）；University of Hertfordshire（赫特福德大学）
This chapter presents a methodology for diagnosis of pigmented skin lesions using convolutional neural networks. The architecture is based on convolu-tional neural networks and it is evaluated using new CNN models as well as re-trained modification of pre-existing CNN models were used. The experi-mental results showed that CNN models pre-trained on big datasets for gen-eral purpose image classification when re-trained in order to identify skin le-sion types offer more accurate results when compared to convolutional neural network models trained explicitly from the dermatoscopic images. The bes…
National Research Council, Institute for the Application of Calculus（国家研究委员会，计算应用研究所）
Skin lesion segmentation is one of the crucial steps for an efficient non-invasive computer-aided early diagnosis of melanoma. This paper investigates how color information, besides saliency, can be used to determine the pigmented lesion region automatically. Unlike most existing segmentation methods using only the saliency in order to discriminate against the skin lesion from the surrounding regions, we propose a novel method employing a binarization process coupled with new perceptual criteria, inspired by the human visual perception, related to the properties of saliency and color of the in…
There has been a concurrent significant improvement in the medical images used to facilitate diagnosis and the performance of machine learning techniques to perform tasks such as classification, detection, and segmentation in recent years. As a result, a rapid increase in the usage of such systems can be observed in the healthcare industry, for instance in the form of medical image classification systems, where these models have achieved diagnostic parity with human physicians. One such application where this can be observed is in computer vision tasks such as the classification of skin lesion…
University of Perugia（佩鲁贾大学）；University of Florence（佛罗伦萨大学）
Medical data classification is typically a challenging task due to imbalance between classes. In this paper, we propose an approach to classify dermatoscopic images from HAM10000 (Human Against Machine with 10000 training images) dataset, consisting of seven imbalanced types of skin lesions, with good precision and low resources requirements. Classification is done by using a pretrained convolutional neural network. We evaluate the accuracy and performance of the proposal and illustrate possible extensions.
Derm-T2IM: Harnessing Synthetic Skin Lesion Data via Stable Diffusion Models for Enhanced Skin Disease Classification using ViT and CNN
College of Science and Engineering, University of Galway（戈尔韦大学科学与工程学院）；School of Computer Science, University of Galway（戈尔韦大学计算机科学学院）；Trinity College Dublin, the University of Dublin（都柏林大学圣三一学院）；St James’s Hospital（圣詹姆斯医院）
本文提出 Derm-T2IM，用调优的 Stable Diffusion 生成多样化皮肤镜病变图像，并验证其可增强 CNN 与 ViT 在两个真实数据集上的分类鲁棒性和泛化性。
Hybrid Approach for Enhancing Lesion Segmentation in Fundus Images
Department of Electrical \& Software Engineering, University of Calgary, Canada.；Department of Computer Science；Physics, Wilfrid Laurier University, Waterloo, Canada.；Dept of Ophthalmology \& Visual Sciences, University of Alberta, Edmonton, Canada.；Wills Eye Hospital, Philadelphia, USA.；Department of Surgery, University of Calgary, Canada.
