Background: Dermoscopy is one of the major imaging modalities used in the diagnosis of melanoma and other pigmented skin lesions. Due to the difficulty and subjectivity of human interpretation, computerized analysis of dermoscopy images has become an important research area. One of the most important steps in dermoscopy image analysis is the automated detection of lesion borders. Methods: In this article, we present a systematic overview of the recent border detection methods in the literature paying particular attention to computational issues and evaluation aspects. Conclusion: Common problems with the existing approaches include the acquisition, size, and diagnostic distribution of the test image set, the evaluation of the results, and the inadequate description of the employed methods. Border determination by dermatologists appears to depend upon higher-level knowledge, therefore it is likely that the incorporation of domain knowledge in automated methods will enable them to perform better, especially in sets of images with a variety of diagnoses.
Background: Dermoscopy is one of the major imaging modalities used in the diagnosis of melanoma and other pigmented skin lesions. Due to the difficulty and subjectivity of human interpretation, automated analysis of dermoscopy images has become an important research area. Border detection is often the first step in this analysis. Methods: In this article, we present an approximate lesion localization method that serves as a preprocessing step for detecting borders in dermoscopy images. In this method, first the black frame around the image is removed using an iterative algorithm. The approxima…
This report summarises our method and validation results for the ISIC Challenge 2018 - Skin Lesion Analysis Towards Melanoma Detection - Task 1: Lesion Segmentation. We present a two-stage method for lesion segmentation with optimised training method and ensemble post-process. Our method achieves state-of-the-art performance on lesion segmentation and we win the first place in ISIC 2018 task1.
Background: Dermoscopy is one of the major imaging modalities used in the diagnosis of melanoma and other pigmented skin lesions. Due to the difficulty and subjectivity of human interpretation, dermoscopy image analysis has become an important research area. One of the most important steps in dermoscopy image analysis is the automated detection of lesion borders. Although numerous methods have been developed for the detection of lesion borders, very few studies were comprehensive in the evaluation of their results. Methods: In this paper, we evaluate five recent border detection methods on a s…
Louisiana State Univ.（路易斯安那州立大学）；Univ. of Electronic Science and Technology of China（电子科技大学）；Univ. of Illinois（伊利诺伊大学）；Hosei Univ.（法政大学）；Loughborough Univ.（拉夫堡大学）
Dermoscopy is one of the major imaging modalities used in the diagnosis of melanoma and other pigmented skin lesions. Due to the difficulty and subjectivity of human interpretation, automated analysis of dermoscopy images has become an important research area. Border detection is often the first step in this analysis. In many cases, the lesion can be roughly separated from the background skin using a thresholding method applied to the blue channel. However, no single thresholding method appears to be robust enough to successfully handle the wide variety of dermoscopy images encountered in clin…
National Engineering Laboratory for Integrated Aero-Space-Ground-Ocean Big Data Application Technology（空天地海一体化大数据应用技术国家工程实验室）；School of Computer Science and Engineering, Northwestern Polytechnical University（西北工业大学计算机学院）
A multi-level deep ensemble (MLDE) model that can be trained in an 'end to end' manner is proposed for skin lesion classification in dermoscopy images. In this model, four pre-trained ResNet-50 networks are used to characterize the multiscale information of skin lesions and are combined by using an adaptive weighting scheme that can be learned during the error back propagation. The proposed MLDE model achieved an average AUC value of 86.5% on the ISIC-skin 2018 official validation dataset, which is substantially higher than the average AUC values achieved by each of four ResNet-50 networks.
Malignant melanoma has one of the most rapidly increasing incidences in the world and has a considerable mortality rate. Early diagnosis is particularly important since melanoma can be cured with prompt excision. Dermoscopy images play an important role in the non-invasive early detection of melanoma [1]. However, melanoma detection using human vision alone can be subjective, inaccurate and poorly reproducible even among experienced dermatologists. This is attributed to the challenges in interpreting images with diverse characteristics including lesions of varying sizes and shapes, lesions tha…
Automatic lesion segmentation in dermoscopy images is an essential step for computer-aided diagnosis of melanoma. The dermoscopy images exhibits rotational and reflectional symmetry, however, this geometric property has not been encoded in the state-of-the-art convolutional neural networks based skin lesion segmentation methods. In this paper, we present a deeply supervised rotation equivariant network for skin lesion segmentation by extending the recent group rotation equivariant network~\cite{cohen2016group}. Specifically, we propose the G-upsampling and G-projection operations to adapt the …
The identification of melanoma involves an integrated analysis of skin lesion images acquired using the clinical and dermoscopy modalities. Dermoscopic images provide a detailed view of the subsurface visual structures that supplement the macroscopic clinical images. Melanoma diagnosis is commonly based on the 7-point visual category checklist (7PC). The 7PC contains intrinsic relationships between categories that can aid classification, such as shared features, correlations, and the contributions of categories towards diagnosis. Manual classification is subjective and prone to intra- and inte…
Skin cancer is one of the most common forms of cancer and its incidence is projected to rise over the next decade. Artificial intelligence is a viable solution to the issue of providing quality care to patients in areas lacking access to trained dermatologists. Considerable progress has been made in the use of automated applications for accurate classification of skin lesions from digital images. In this manuscript, we discuss the design and implementation of a deep learning algorithm for classification of dermoscopy images from the HAM10000 Dataset. We trained a convolutional neural network b…
Institute of Medical Technology, Hamburg University of Technology（汉堡工业大学医学技术研究所）
The initial assessment of skin lesions is typically based on dermoscopic images. As this is a difficult and time-consuming task, machine learning methods using dermoscopic images have been proposed to assist human experts. Other approaches have studied electrical impedance spectroscopy (EIS) as a basis for clinical decision support systems. Both methods represent different ways of measuring skin lesion properties as dermoscopy relies on visible light and EIS uses electric currents. Thus, the two methods might carry complementary features for lesion classification. Therefore, we propose joint d…
Indian Statistical Institute（印度统计研究所）；Indian Institute of Technology, Guwahati（印度理工学院古瓦哈提分校）
In this paper, a deep neural network based ensemble method is experimented for automatic identification of skin disease from dermoscopic images. The developed algorithm is applied on the task3 of the ISIC 2018 challenge dataset (Skin Lesion Analysis Towards Melanoma Detection).
Exploiting learning algorithms under scarce data regimes is a limitation and a reality of the medical imaging field. In an attempt to mitigate the problem, we propose a data augmentation protocol based on generative adversarial networks. We condition the networks at a pixel-level (segmentation mask) and at a global-level information (acquisition environment or lesion type). Such conditioning provides immediate access to the image-label pairs while controlling global class specific appearance of the synthesized images. To stimulate synthesis of the features relevant for the segmentation task, a…
We propose a novel approach to identify one of the most significant dermoscopic criteria in the diagnosis of Cutaneous Melanoma: the Blue-whitish structure. In this paper, we achieve this goal in a Multiple Instance Learning framework using only image-level labels of whether the feature is present or not. As the output, we predict the image classification label and as well localize the feature in the image. Experiments are conducted on a challenging dataset with results outperforming state-of-the-art. This study provides an improvement on the scope of modelling for computerized image analysis …
Louisiana State University in Shreveport（路易斯安那州立大学什里夫波特分校）；Hosei University（法政大学）；Stoecker & Associates（斯托克联合公司）；Missouri University of Science and Technology（密苏里科技大学）；University of Miami School of Medicine（迈阿密大学医学院）；Second University of Naples（那不勒斯第二大学）；Queensland Institute of Dermatology, University of Queensland（昆士兰大学昆士兰皮肤病研究所）
Dermoscopy is a non-invasive skin imaging technique, which permits visualization of features of pigmented melanocytic neoplasms that are not discernable by examination with the naked eye. One of the most important features for the diagnosis of melanoma in dermoscopy images is the blue-white veil (irregular, structureless areas of confluent blue pigmentation with an overlying white "ground-glass" film). In this article, we present a machine learning approach to the detection of blue-white veil and related structures in dermoscopy images. The method involves contextual pixel classification using…
University of Saskatchewan（萨斯喀彻温大学）；Philips Canada（加拿大飞利浦）
Melanoma is a curable aggressive skin cancer if detected early. Typically, the diagnosis involves initial screening with subsequent biopsy and histopathological examination if necessary. Computer aided diagnosis offers an objective score that is independent of clinical experience and the potential to lower the workload of a dermatologist. In the recent past, success of deep learning algorithms in the field of general computer vision has motivated successful application of supervised deep learning methods in computer aided melanoma recognition. However, large quantities of labeled images are re…
Beihang University（北京航空航天大学）；Shanghai Aerospace Control Technology Institute（上海航天控制技术研究所）；Peking Union Medical College Hospital（北京协和医院）；Chinese Academy of Medical Sciences and Peking Union Medical College（中国医学科学院北京协和医学院）
The computer-aided diagnosis (CAD) system can provide a reference basis for the clinical diagnosis of skin diseases. Convolutional neural networks (CNNs) can not only extract visual elements such as colors and shapes but also semantic features. As such they have made great improvements in many tasks of dermoscopy images. The imaging of dermoscopy has no principal orientation, indicating that there are a large number of skin lesion rotations in the datasets. However, CNNs lack rotation invariance, which is bound to affect the robustness of CNNs against rotations. To tackle this issue, we propos…
This paper proposes an innovative method for segmentation of skin lesions in dermoscopy images developed by the authors, based on fuzzy classification of pixels and histogram thresholding.
Faculty of Informatics, University of Debrecen（德布勒森大学信息学院）
Skin cancer is a major public health problem, with over 5 million newly diagnosed cases in the United States each year. Melanoma is the deadliest form of skin cancer, responsible for over 9,000 deaths each year. In this paper, we propose an ensemble of deep convolutional neural networks to classify dermoscopy images into three classes. To achieve the highest classification accuracy, we fuse the outputs of the softmax layers of four different neural architectures. For aggregation, we consider the individual accuracies of the networks weighted by the confidence values provided by their final sof…
Stoecker & Associates；Louisiana State University（路易斯安那州立大学）
The incidence of malignant melanoma continues to increase worldwide. This cancer can strike at any age; it is one of the leading causes of loss of life in young persons. Since this cancer is visible on the skin, it is potentially detectable at a very early stage when it is curable. New developments have converged to make fully automatic early melanoma detection a real possibility. First, the advent of dermoscopy has enabled a dramatic boost in clinical diagnostic ability to the point that melanoma can be detected in the clinic at the very earliest stages. The global adoption of this technology…
Samsung Advanced Institute of Health Sciences and Technology（三星健康科学与技术高级研究院）；Sungkyunkwan University（成均馆大学）；Samsung Medical Center（三星医疗中心）
As skin cancer is one of the most frequent cancers globally, accurate, non-invasive dermoscopy-based diagnosis becomes essential and promising. A task of the Part 3 of the ISIC Skin Image Analysis Challenge at MICCAI 2018 is to predict seven disease classes with skin lesion images, including melanoma (MEL), melanocytic nevus (NV), basal cell carcinoma (BCC), actinic keratosis / Bowen's disease (intraepithelial carcinoma) (AKIEC), benign keratosis (solar lentigo / seborrheic keratosis / lichen planus-like keratosis) (BKL), dermatofibroma (DF) and vascular lesion (VASC) as defined by the Interna…
Isfahan University of Technology（伊斯法罕理工大学）；University of British Columbia（不列颠哥伦比亚大学）；University of Michigan（密歇根大学）；McMaster University（麦克马斯特大学）
One of the essential tasks in medical image analysis is segmentation and accurate detection of borders. Lesion segmentation in skin images is an essential step in the computerized detection of skin cancer. However, many of the state-of-the-art segmentation methods have deficiencies in their border detection phase. In this paper, a new class of fully convolutional network is proposed, with new dense pooling layers for segmentation of lesion regions in skin images. This network leads to highly accurate segmentation of lesions on skin lesion datasets which outperforms state-of-the-art algorithms …
In this work, we explore the issue of the inter-annotator agreement for training and evaluating automated segmentation of skin lesions. We explore what different degrees of agreement represent, and how they affect different use cases for segmentation. We also evaluate how conditioning the ground truths using different (but very simple) algorithms may help to enhance agreement and may be appropriate for some use cases. The segmentation of skin lesions is a cornerstone task for automated skin lesion analysis, useful both as an end-result to locate/detect the lesions and as an ancillary task for …
Melanoma is the deadliest form of skin cancer. While curable with early detection, only highly trained specialists are capable of accurately recognizing the disease. As expertise is in limited supply, automated systems capable of identifying disease could save lives, reduce unnecessary biopsies, and reduce costs. Toward this goal, we propose a system that combines recent developments in deep learning with established machine learning approaches, creating ensembles of methods that are capable of segmenting skin lesions, as well as analyzing the detected area and surrounding tissue for melanoma …
Computer Vision Institute, College of Computer Science and Software Engineering, Shenzhen University（深圳大学计算机与软件学院计算机视觉研究所）
Skin lesion is a severe disease in world-wide extent. Early detection of melanoma in dermoscopy images significantly increases the survival rate. However, the accurate recognition of melanoma is extremely challenging due to the following reasons, e.g. low contrast between lesions and skin, visual similarity between melanoma and non-melanoma lesions, etc. Hence, reliable automatic detection of skin tumors is very useful to increase the accuracy and efficiency of pathologists. International Skin Imaging Collaboration (ISIC) is a challenge focusing on the automatic analysis of skin lesion. In thi…
Missouri University of Science and Technology（密苏里科技大学）；Idaho National Laboratory（爱达荷国家实验室）
Oral lesions are important findings on computed tomography (CT) images. In this study, a fully automatic method to detect oral lesions in mandibular region from dental CT images is proposed. Two methods were developed to recognize two types of lesions namely (1) Close border (CB) lesions and (2) Open border (OB) lesions, which cover most of the lesion types that can be found on CT images. For the detection of CB lesions, fifteen features were extracted from each initial lesion candidates and multi layer perceptron (MLP) neural network was used to classify suspicious regions. Moreover, OB lesio…
University of Electronic Science and Technology of China（电子科技大学）
Dermoscopy image detection stays a tough task due to the weak distinguishable property of the object.Although the deep convolution neural network signifigantly boosted the performance on prevelance computer vision tasks in recent years,there remains a room to explore more robust and precise models to the problem of low contrast image segmentation.Towards the challenge of Lesion Segmentation in ISBI 2017,we built a symmetrical identity inception fully convolution network which is based on only 10 reversible inception blocks,every block composed of four convolution branches with combination of d…
Lesion segmentation from the surrounding skin is the first task for developing automatic Computer-Aided Diagnosis of skin cancer. Variant features of lesion like uneven distribution of color, irregular shape, border and texture make this task challenging. The contribution of this paper is to present and compare two different approaches to skin lesion segmentation. The first approach uses watershed, while the second approach uses mean-shift. Pre-processing steps were performed in both approaches for removing hair and dark borders of microscopic images. The Evaluation of the proposed approaches …
University of Electronic Science and Technology of China（电子科技大学）
With a large influx of dermoscopy images and a growing shortage of dermatologists, automatic dermoscopic image analysis plays an essential role in skin cancer diagnosis. In this paper, a new deep fully convolutional neural network (FCNN) is proposed to automatically segment melanoma out of skin images by end-to-end learning with only pixels and labels as inputs. Our proposed FCNN is capable of using both local and global information to segment melanoma by adopting skipping layers. The public benchmark database consisting of 150 validation images, 600 test images and 2000 training images in the…
Department of CS & IT, SUIT Peshawar（白沙瓦SUIT计算机科学与信息技术系）
Skin lesion segmentation can be rather a challenging task owing to the presence of artifacts, low contrast between lesion and boundary, color variegation, fuzzy skin lesion borders and heterogeneous background in dermoscopy images. In this paper, we propose a simple yet effective saliency-based approach derived in the frequency and spatial domain to detect pigmented skin lesion. Two color models are utilized for the construction of these maps. We suggest a different metric for each color model to design map in the spatial domain via color features. The map in the frequency domain is generated …
University of Burgundy（勃艮第大学）；University of Cassino（卡西诺大学）；University of Girona（赫罗纳大学）
Skin lesion segmentation is one of the first steps towards automatic Computer-Aided Diagnosis of skin cancer. Vast variety in the appearance of the skin lesion makes this task very challenging. The contribution of this paper is to apply a power foreground extraction technique called GrabCut for automatic skin lesion segmentation with minimal human interaction in HSV color space. Preprocessing was performed for removing the outer black border. Jaccard Index was measured to evaluate the performance of the segmentation method. On average, 0.71 Jaccard Index was achieved on 1000 images from ISIC c…
Hospital Clínic Barcelona, Universitat de Barcelona, IDIBAPS（巴塞罗那临床医院，巴塞罗那大学，IDIBAPS）；IBM Research AI, T J Watson Research Center（IBM研究AI，T J Watson研究中心）；Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center（医学部皮肤科，纪念斯隆-凯特琳癌症中心）；Kitware；Signal Theory and Communications, Universitat Politècnica de Catalunya（信号理论与通信，加泰罗尼亚理工大学）；Melanoma Unit, Dermatology Department, Hospital Clínic Barcelona, Universitat de Barcelona, IDIBAPS（黑素瘤科，皮肤科，巴塞罗那临床医院，巴塞罗那大学，IDIBAPS）
This article summarizes the BCN20000 dataset, composed of 19424 dermoscopic images of skin lesions captured from 2010 to 2016 in the facilities of the Hospital Clínic in Barcelona. With this dataset, we aim to study the problem of unconstrained classification of dermoscopic images of skin cancer, including lesions found in hard-to-diagnose locations (nails and mucosa), large lesions which do not fit in the aperture of the dermoscopy device, and hypo-pigmented lesions. The BCN20000 will be provided to the participants of the ISIC Challenge 2019, where they will be asked to train algorithms to c…
The University of Adelaide（阿德莱德大学）；Australian Institute for Machine Learning（澳大利亚机器学习研究所）；Delft University of Technology（代尔夫特理工大学）；Queensland University of Technology（昆士兰科技大学）
There is a heated debate on how to interpret the decisions provided by deep learning models (DLM), where the main approaches rely on the visualization of salient regions to interpret the DLM classification process. However, these approaches generally fail to satisfy three conditions for the problem of lesion detection from medical images: 1) for images with lesions, all salient regions should represent lesions, 2) for images containing no lesions, no salient region should be produced,and 3) lesions are generally small with relatively smooth borders. We propose a new model-agnostic paradigm to …
Instituto de Telecomunicações（电信研究所）；Polytechnic Institute of Leiria（莱里亚理工学院）；University of Coimbra（科英布拉大学）
Segmentation is a key stage in dermoscopic image processing, where the accuracy of the border line that defines skin lesions is of utmost importance for subsequent algorithms (e.g., classification) and computer-aided early diagnosis of serious medical conditions. This paper proposes a novel segmentation method based on Local Binary Patterns (LBP), where LBP and K-Means clustering are combined to achieve a detailed delineation in dermoscopic images. In comparison with usual dermatologist-like segmentation (i.e., the available ground-truth), the proposed method is capable of finding more realist…
Yale University（耶鲁大学）；Cleerly Inc（Cleerly公司）；Dana-Farber Cancer Institute（丹娜-法伯癌症研究所）；East China University of Science and Technology（华东理工大学）
Melanoma is a type of skin cancer with the most rapidly increasing incidence. Early detection of melanoma using dermoscopy images significantly increases patients' survival rate. However, accurately classifying skin lesions by eye, especially in the early stage of melanoma, is extremely challenging for the dermatologists. Hence, the discovery of reliable biomarkers will be meaningful for melanoma diagnosis. Recent years, the value of deep learning empowered computer-assisted diagnose has been shown in biomedical imaging based decision making. However, much research focuses on improving disease…
Duke University（杜克大学）；Duke Institute for Health Innovation（杜克健康创新研究所）
We consider machine-learning-based malignancy prediction and lesion identification from clinical dermatological images, which can be indistinctly acquired via smartphone or dermoscopy capture. Additionally, we do not assume that images contain single lesions, thus the framework supports both focal or wide-field images. Specifically, we propose a two-stage approach in which we first identify all lesions present in the image regardless of sub-type or likelihood of malignancy, then it estimates their likelihood of malignancy, and through aggregation, it also generates an image-level likelihood of…
GraphDerm: Fusing Imaging, Physical Scale, and Metadata in a Population-Graph Classifier for Dermoscopic Lesions
School of Computer Science, Institute for Research in Fundamental Sciences (IPM)（计算机科学学院，基础科学研究所（IPM））；Department of Physics, Shahid Beheshti University（物理系，肖德·贝赫谢什提大学）；Faculty of Science, University of Tehran（科学学院，德黑兰大学）；Fatemeh Zahra Hospital, Alborz University of Medical Sciences（法特梅·扎拉医院，阿尔bor兹医学科学大学）；Department of Electrical and Computer Engineering, Sungkyunkwan University（电气与计算机工程系，成均馆大学）；Department of Computer Science and Engineering, Shahid Beheshti University（计算机科学与工程系，肖德·贝赫谢什提大学）；Autoimmune Bullous Diseases Research Center, Razi Hospital, Tehran University of Medical Sciences（自身免疫性水疱病研究中心，拉齐医院，德黑兰医学科学大学）
Isfahan University of Technology（伊斯法罕理工大学）；University of Michigan（密歇根大学）
Melanoma is amongst most aggressive types of cancer. However, it is highly curable if detected in its early stages. Prescreening of suspicious moles and lesions for malignancy is of great importance. Detection can be done by images captured by standard cameras, which are more preferable due to low cost and availability. One important step in computerized evaluation of skin lesions is accurate detection of lesion region, i.e. segmentation of an image into two regions as lesion and normal skin. Accurate segmentation can be challenging due to burdens such as illumination variation and low contras…
FH Joanneum University of Applied Sciences（约阿内姆应用科学大学）
Skin cancer is the most common cancer worldwide, with melanoma being the deadliest form. Dermoscopy is a skin imaging modality that has shown an improvement in the diagnosis of skin cancer compared to visual examination without support. We evaluate the current state of the art in the classification of dermoscopic images based on the ISIC-2019 Challenge for the classification of skin lesions and current literature. Various deep neural network architectures pre-trained on the ImageNet data set are adapted to a combined training data set comprised of publicly available dermoscopic and clinical im…
Existing studies for automated melanoma diagnosis are based on single-time point images of lesions. However, melanocytic lesions de facto are progressively evolving and, moreover, benign lesions can progress into malignant melanoma. Ignoring cross-time morphological changes of lesions thus may lead to misdiagnosis in borderline cases. Based on the fact that dermatologists diagnose ambiguous skin lesions by evaluating the dermoscopic changes over time via follow-up examination, in this study, we propose an automated framework for melanoma diagnosis using sequential dermoscopic images. To captur…
Melanoma spreads through metastasis, and therefore it has been proven to be very fatal. Statistical evidence has revealed that the majority of deaths resulting from skin cancer are as a result of melanoma. Further investigations have shown that the survival rates in patients depend on the stage of the infection; early detection and intervention of melanoma implicates higher chances of cure. Clinical diagnosis and prognosis of melanoma is challenging since the processes are prone to misdiagnosis and inaccuracies due to doctors subjectivity. This paper proposes an innovative and fully functional…
Nanyang Technological University（南洋理工大学）；University of British Columbia（不列颠哥伦比亚大学）；Vancouver Coast Health Research Institute（温哥华海岸健康研究所）；BC Cancer（不列颠哥伦比亚癌症中心）
Skin cancer is one of the most common types of malignancy, affecting a large population and causing a heavy economic burden worldwide. Over the last few years, computer-aided diagnosis has been rapidly developed and make great progress in healthcare and medical practices due to the advances in artificial intelligence. However, most studies in skin cancer detection keep pursuing high prediction accuracies without considering the limitation of computing resources on portable devices. In this case, knowledge distillation (KD) has been proven as an efficient tool to help improve the adaptability o…
Tlemcen University（特莱姆森大学）；Université de Bourgogne（勃艮第大学）
During the last years, computer vision-based diagnosis systems have been widely used in several hospitals and dermatology clinics, aiming at the early detection of malignant melanoma tumor, which is among the most frequent types of skin cancer. In this work, we present an automated diagnosis system based on the ABCD rule used in clinical diagnosis in order to discriminate benign from malignant skin lesions. First, to reduce the influence of small structures, a preprocessing step based on morphological and fast marching schemes is used. In the second step, an unsupervised approach for lesion se…
Adapting Segment Anything Model 3 for Concept-Driven Lesion Segmentation in Medical Images: An Experimental Study
The Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, University of Texas Southwestern Medical Center（德克萨斯大学西南医学中心放射肿瘤学系医学人工智能与自动化（MAIA）实验室）；Medical Image Processing Group, Department of Radiology, University of Pennsylvania（宾夕法尼亚大学放射学系医学图像处理组）；Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center（德克萨斯大学西南医学中心内科学系消化与肝脏疾病科）
Central Electronics Engineering Research Institute, CSIR Madras Complex（CSIR马德拉斯综合体中央电子工程研究所）；University of Bridgeport（桥港大学）
Image segmentation and classification are the two main fundamental steps in pattern recognition. To perform medical image segmentation or classification with deep learning models, it requires training on large image dataset with annotation. The dermoscopy images (ISIC archive) considered for this work does not have ground truth information for lesion segmentation. Performing manual labelling on this dataset is time-consuming. To overcome this issue, self-learning annotation scheme was proposed in the two-stage deep learning algorithm. The two-stage deep learning algorithm consists of U-Net seg…
University of Barcelona（巴塞罗那大学）；Universitat Rovira i Virgili（罗维拉-维尔吉利大学）；Khalifa University of Science and Technology（哈利法科学技术大学）；Mil-kin Inc.（Mil-kin公司）；Dhaka Medical College Hospital（达卡医学院附属医院）；University of Warwick（华威大学）；University of Toulouse（图卢兹大学）
The determination of precise skin lesion boundaries in dermoscopic images using automated methods faces many challenges, most importantly, the presence of hair, inconspicuous lesion edges and low contrast in dermoscopic images, and variability in the color, texture and shapes of skin lesions. Existing deep learning-based skin lesion segmentation algorithms are expensive in terms of computational time and memory. Consequently, running such segmentation algorithms requires a powerful GPU and high bandwidth memory, which are not available in dermoscopy devices. Thus, this article aims to achieve …
Boston Children's Hospital（波士顿儿童医院）；Harvard Medical School（哈佛医学院）；Northeastern University（东北大学）
Fully convolutional deep neural networks have been asserted to be fast and precise frameworks with great potential in image segmentation. One of the major challenges in training such networks raises when data is unbalanced, which is common in many medical imaging applications such as lesion segmentation where lesion class voxels are often much lower in numbers than non-lesion voxels. A trained network with unbalanced data may make predictions with high precision and low recall, being severely biased towards the non-lesion class which is particularly undesired in most medical applications where…
Deeply Supervised Skin Lesions Diagnosis with Stage and Branch Attention
City University of Hong Kong（香港城市大学）；Beijing University of Posts and Telecommunications（北京邮电大学）；Shenzhen Research Institute, City University of Hong Kong（香港城市大学深圳研究院）
Large medical image data sets with high dimensionality require substantial amount of computation time for data creation and data processing. This paper presents a novel generalized method that finds optimal image-based feature sets that reduce computational time complexity while maximizing overall classification accuracy for detection of diabetic retinopathy (DR). First, region-based and pixel-based features are extracted from fundus images for classification of DR lesions and vessel-like structures. Next, feature ranking strategies are used to distinguish the optimal classification feature se…
Indian Institute of Information Technology, Design and Manufacturing, Kancheepuram（印度信息技术与设计制造学院，坎奇普拉姆）
Skin cancer is the most common cancer in the existing world constituting one-third of the cancer cases. Benign skin cancers are not fatal, can be cured with proper medication. But it is not the same as the malignant skin cancers. In the case of malignant melanoma, in its peak stage, the maximum life expectancy is less than or equal to 5 years. But, it can be cured if detected in early stages. Though there are numerous clinical procedures, the accuracy of diagnosis falls between 49% to 81% and is time-consuming. So, dermoscopy has been brought into the picture. It helped in increasing the accur…
School of Computer Science, Fudan University（复旦大学计算机科学学院）；Johns Hopkins University（约翰斯·霍普金斯大学）
Recent advances in automated skin cancer diagnosis have yielded performance on par with board-certified dermatologists. However, these approaches formulated skin cancer diagnosis as a simple classification task, dismissing the potential benefit from lesion segmentation. We argue that an accurate lesion segmentation can supplement the classification task with additive lesion information, such as asymmetry, border, intensity, and physical size; in turn, a faithful lesion classification can support the segmentation task with discriminant lesion features. To this end, this paper proposes a new mul…
