R. P. Johnson, V. A. Bashkirov, G. Coutrakon, V. Giacometti, P. Karbasi, N. T. Karonis, C. E. Ordoñez, M. Pankuch, H. F. -W. Sadrozinski, K. E. Schubert, R. W. Schulte
备注:
Conference on the Application of Accelerators in Research and Industry, CAARI 2016, 30 October to 4 November 2016, Ft. Worth, TX, USA
我们正在探索低剂量质子射线照相术和计算机断层成像(pCT)技术,以提高质子治疗计划的准确性,并在治疗时提供无伪影图像进行验证和适应性治疗。在这里,我们报告了我们的原型pCT头部扫描仪的全面光束测试结果。探测器系统和数据采集可实现每秒超过一百万个单独测量的质子的持续速率,允许在六分钟或更短的射束时间内完成完整的CT扫描。为了评估质子射线照相以及计算机断层成像扫描仪的性能,我们在Northwestern Medicine Chicago质子中心进行了多次体模扫描,包括设计用于评估空间分辨率的定制体模、评估相对阻止本领测量的体模和剂量测定体模。一些图像,性能,和剂量测定结果,从这些幻影扫描的仪器,数据采集系统和校准方法的描述一起。
英文摘要:
We are exploring low-dose proton radiography and computed tomography (pCT) as techniques to improve the accuracy of proton treatment planning and to provide artifact-free images for verification and adaptive therapy at the time of treatment. Here we report on comprehensive beam test results with our prototype pCT head scanner. The detector system and data acquisition attain a sustained rate of more than a million protons individually measured per second, allowing a full CT scan to be completed in six minutes or less of beam time. In order to assess the performance of the scanner for proton radiography as well as computed tomography, we have performed numerous scans of phantoms at the Northwestern Medicine Chicago Proton Center including a custom phantom designed to assess the spatial resolution, a phantom to assess the measurement of relative stopping power, and a dosimetry phantom. Some images, performance, and dosimetry results from those phantom scans are presented together with a description of the instrument, the data acquisition system, and the calibration methods.
Birth of the Coil: another Milestone towards a fully reproducible low-field MRI scanner for head-imaging
Istituto Nazionale di Ricerca Metrologica (INRiM)(意大利国家计量研究所);Institute of Biomedical Imaging, Graz University of Technology(格拉茨工业大学生物医学成像研究所);Physikalisch-Technische Bundesanstalt (PTB) Braunschweig and Berlin(德国联邦物理技术研究院);Universidad Comunera(科穆内拉大学);University of Alberta(阿尔伯塔大学);Cross Cancer Institute(交叉癌症研究所)
Institut de Física d’Altes Energies (IFAE), The Barcelona Institute of Science and Technology (BIST), Edifici CN, Universitat Autònoma de Barcelona (UAB)(高能物理研究所,巴塞罗那科学与技术研究院,CN大楼,巴塞罗那自治大学)
High-spatial resolution, high-quality white matter tractography using DTI with dynamic slice-by-slice B0 shimming in a head-only high-gradient performance 3T MRI scanner
Proton therapy range uncertainty reduction using vendor-agnostic tissue characterization on a virtual photon-counting CT head scan
Vinaver Medical(维纳弗医学);Faculty of Medicine, University of Novi Sad(诺维萨德大学医学院);Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University(杜克大学卡尔·E·拉文先进成像实验室与虚拟成像试验中心);Centro Nazionale di Adroterapia Oncologica (CNAO)(国家肿瘤质子治疗中心);Department of Radiology, Duke University(杜克大学放射系)
Generalizability issues with deep learning models in medicine and their potential solutions: illustrated with Cone-Beam Computed Tomography (CBCT) to Computed Tomography (CT) image conversion
University of Texas Southwestern Medical Center(德克萨斯大学西南医学中心)
Design and construction of a wireless robot that simulates head movements in cone beam computed tomography imaging
Hamedan University of Technology(哈马丹理工大学);Hamadan University of Medical Sciences(哈马丹医科大学);Pprime Institute CNRS(法国国家科学研究中心Pprime研究所);ENSMA(国立高等机械与航空技术学院);University of Poitiers(普瓦捷大学)
Performance of Hull-Detection Algorithms For Proton Computed Tomography Reconstruction
Baylor University(贝勒大学);California State University, San Bernardino(加州州立大学圣贝纳迪诺分校);University of Haifa(海法大学);Loma Linda University Medical Center(洛马林达大学医学中心)