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arXiv 1310.2285math.AP
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细胞运动的相场模型:亚临界情况下的锐界面极限

Phase field model of cell motility: sharp interface limit in sub-critical case

Leonid Berlyand, Volodymyr Rybalko, Mykhailo Potomkin

摘要:

我们考虑一个系统的两个偏微分方程所产生的运动的真核细胞的基板上的建模。该系统由Allen-Cahn方程的标量相场函数耦合的另一个矢量抛物型方程的肌动蛋白丝网络的方向。该系统的两个关键特性是(i)耦合项中存在梯度(梯度耦合)和(ii)质量(体积)保持约束。我们首先证明了尖锐的界面性质的初始条件是保持在时间。接下来,我们正式推导出界面的运动方程,该运动方程是由由于性质(i)-(ii)而出现的非线性项扰动的中曲率运动。这个新的术语导致了界面运动的令人惊讶的特征。由于这些性质,最大值原理和经典的比较技术不适用于这个系统。此外,该系统不能以梯度流的形式编写,这就是为什么最近开发的伽玛收敛技术也不能用于形式推导的证明。这种理由是在一个一维模型问题,它导致了稳定的结果,在一类“尖锐的接口”的初始数据。

英文摘要:

We consider a system of two PDEs arising in modeling of motility of eukariotic cells on substrates. This system consists of the Allen-Cahn equation for the scalar phase field function coupled with another vectorial parabolic equation for the orientation of the actin filament network. The two key properties of this system are (i) presence of gradients in the coupling terms (gradient coupling) and (ii) mass (volume) preservation constraints. We first prove that the sharp interface property of initial conditions is preserved in time. Next we formally derive the equation of the motion of the interface, which is the mean curvature motion perturbed by a nonlinear term that appears due to the properties (i)-(ii). This novel term leads to surprising features of the the motion of the interface. Because of these properties maximum principle and classical comparison techniques do not apply to this system. Furthermore, the system can not be written in a form of gradient flow, which is why recently developed Gamma-convergence techniques also can not be used for the justification of the formal derivation. Such justification is presented in a one-dimensional model problem and it leads to a stability result in a class of 'sharp interface' initial data.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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