The aim of this work is to develop a method for automatic segmentation of the liver based on a priori knowledge of the image, such as location and shape of the liver.
Montreal Institute for Learning Algorithms (MILA)(蒙特利尔学习算法研究所(MILA));Centre de recherche du CHUM (CRCHUM)(蒙特利尔大学医院研究中心(CRCHUM))
We propose a model for the joint segmentation of the liver and liver lesions in computed tomography (CT) volumes. We build the model from two fully convolutional networks, connected in tandem and trained together end-to-end. We evaluate our approach on the 2017 MICCAI Liver Tumour Segmentation Challenge, attaining competitive liver and liver lesion detection and segmentation scores across a wide range of metrics. Unlike other top performing methods, our model output post-processing is trivial, we do not use data external to the challenge, and we propose a simple single-stage model that is trai…
Indian Institute of Technology, Madras(马德拉斯印度理工学院)
In this paper we propose a fully automatic 2-stage cascaded approach for segmentation of liver and its tumors in CT (Computed Tomography) images using densely connected fully convolutional neural network (DenseNet). We independently train liver and tumor segmentation models and cascade them for a combined segmentation of the liver and its tumor. The first stage involves segmentation of liver and the second stage uses the first stage's segmentation results for localization of liver and henceforth tumor segmentations inside liver region. The liver model was trained on the down-sampled axial slic…
Yokohama City University Medical Center(横滨市立大学医学中心)
We present a fully automatic method employing convolutional neural networks based on the 2D U-net architecture and random forest classifier to solve the automatic liver lesion segmentation problem of the ISBI 2017 Liver Tumor Segmentation Challenge (LiTS). In order to constrain the ROI in which the tumors could be located, a liver segmentation is performed first. For the organ segmentation, an ensemble of convolutional networks is trained to segment a liver using a set of 179 liver CT datasets from liver surgery planning. Inside of the liver ROI a neural network, trained using 127 challenge tr…
Automatic segmentation of liver and its tumors is an essential step for extracting quantitative imaging biomarkers for accurate tumor detection, diagnosis, prognosis and assessment of tumor response to treatment. MICCAI 2017 Liver Tumor Segmentation Challenge (LiTS) provides a common platform for comparing different automatic algorithms on contrast-enhanced abdominal CT images in tasks including 1) liver segmentation, 2) liver tumor segmentation, and 3) tumor burden estimation. We participate this challenge by developing a hierarchical framework based on deep fully convolutional-deconvolutiona…
Technical University of Munich(慕尼黑工业大学);University of California, Irvine(加利福尼亚大学尔湾分校)
The segmentation of liver lesions is crucial for detection, diagnosis and monitoring progression of liver cancer. However, design of accurate automated methods remains challenging due to high noise in CT scans, low contrast between liver and lesions, as well as large lesion variability. We propose a 3D automatic, unsupervised method for liver lesions segmentation using a phase separation approach. It is assumed that liver is a mixture of two phases: healthy liver and lesions, represented by different image intensities polluted by noise. The Cahn-Hilliard equation is used to remove the noise an…
Liver lesion segmentation is an important step for liver cancer diagnosis, treatment planning and treatment evaluation. LiTS (Liver Tumor Segmentation Challenge) provides a common testbed for comparing different automatic liver lesion segmentation methods. We participate in this challenge by developing a deep convolutional neural network (DCNN) method. The particular DCNN model works in 2.5D in that it takes a stack of adjacent slices as input and produces the segmentation map corresponding to the center slice. The model has 32 layers in total and makes use of both long range concatenation con…
Fraunhofer MEVIS(弗劳恩霍夫医学图像计算研究所);University of Bremen(不来梅大学);Radboud University(拉德堡德大学);Yokohama City University(横滨市立大学)
Various approaches for liver segmentation in CT have been proposed: Besides statistical shape models, which played a major role in this research area, novel approaches on the basis of convolutional neural networks have been introduced recently. Using a set of 219 liver CT datasets with reference segmentations from liver surgery planning, we evaluate the performance of several neural network classifiers based on 2D and 3D U-net architectures. An interesting observation is that slice-wise approaches perform surprisingly well, with mean and median Dice coefficients above 0.97, and may be preferab…
Segmentation of medical images is a challenging task owing to their complexity. A standard segmentation problem within Magnetic Resonance Imaging (MRI) is the task of labeling voxels according to their tissue type. Image segmentation provides volumetric quantification of liver area and thus helps in the diagnosis of disorders, such as Hepatitis, Cirrhosis, Jaundice, Hemochromatosis etc.This work deals with comparison of segmentation by applying Level Set Method,Fuzzy Level Information C-Means Clustering Algorithm and Gradient Vector Flow Snake Algorithm.The results are compared using the param…
Automatic segmentation of medical images is among most demanded works in the medical information field since it saves time of the experts in the field and avoids human error factors. In this work, a method based on Conditional Adversarial Networks and Fully Convolutional Networks is proposed for the automatic segmentation of the liver MRIs. The proposed method, without any post-processing, is achieved the second place in the SIU Liver Segmentation Challenge 2018, data of which is provided by Dokuz Eylül University. In this paper, some improvements for the post-processing step are also proposed…
Isfahan University of Technology(伊斯法罕理工大学);University of Michigan(密歇根大学)
The need for CT scan analysis is growing for pre-diagnosis and therapy of abdominal organs. Automatic organ segmentation of abdominal CT scan can help radiologists analyze the scans faster and segment organ images with fewer errors. However, existing methods are not efficient enough to perform the segmentation process for victims of accidents and emergencies situations. In this paper we propose an efficient liver segmentation with our 3D to 2D fully connected network (3D-2D-FCN). The segmented mask is enhanced by means of conditional random field on the organ's border. Consequently, we segment…
Technische Universität München(慕尼黑工业大学);LMU Hospital Grosshadern(LMU格罗斯哈德恩医院)
Automatic segmentation of the liver and its lesion is an important step towards deriving quantitative biomarkers for accurate clinical diagnosis and computer-aided decision support systems. This paper presents a method to automatically segment liver and lesions in CT abdomen images using cascaded fully convolutional neural networks (CFCNs) and dense 3D conditional random fields (CRFs). We train and cascade two FCNs for a combined segmentation of the liver and its lesions. In the first step, we train a FCN to segment the liver as ROI input for a second FCN. The second FCN solely segments lesion…
The Chinese University of Hong Kong(香港中文大学);Imsight Medical Technology, Inc.(伊赛智能医疗科技有限公司)
Liver cancer is one of the leading causes of cancer death. To assist doctors in hepatocellular carcinoma diagnosis and treatment planning, an accurate and automatic liver and tumor segmentation method is highly demanded in the clinical practice. Recently, fully convolutional neural networks (FCNs), including 2D and 3D FCNs, serve as the back-bone in many volumetric image segmentation. However, 2D convolutions can not fully leverage the spatial information along the third dimension while 3D convolutions suffer from high computational cost and GPU memory consumption. To address these issues, we …
We propose a computationally efficient architecture that learns to segment lesions from CT images of the liver. The proposed architecture uses bilinear interpolation with sub-pixel convolution at the last layer to upscale the course feature in bottle neck architecture. Since bilinear interpolation and sub-pixel convolution do not have any learnable parameter, our overall model is faster and occupies less memory footprint than the traditional U-net. We evaluate our proposed architecture on the highly competitive dataset of 2017 Liver Tumor Segmentation (LiTS) Challenge. Our method achieves comp…
Stanford(斯坦福大学);Siemens Medical Solutions USA Inc(西门子医疗解决方案美国公司)
We propose a fully-automated method for accurate and robust detection and segmentation of potentially cancerous lesions found in the liver and in lymph nodes. The process is performed in three steps, including organ detection, lesion detection and lesion segmentation. Our method applies machine learning techniques such as marginal space learning and convolutional neural networks, as well as active contour models. The method proves to be robust in its handling of extremely high lesion diversity. We tested our method on volumetric computed tomography (CT) images, including 42 volumes containing …
Automatic liver segmentation in 3D medical images is essential in many clinical applications, such as pathological diagnosis of hepatic diseases, surgical planning, and postoperative assessment. However, it is still a very challenging task due to the complex background, fuzzy boundary, and various appearance of liver. In this paper, we propose an automatic and efficient algorithm to segment liver from 3D CT volumes. A deep image-to-image network (DI2IN) is first deployed to generate the liver segmentation, employing a convolutional encoder-decoder architecture combined with multi-level feature…
Leibniz University Hannover(汉诺威莱布尼茨大学);TU Dresden(德累斯顿工业大学)
In this paper, a novel framework for automated liver segmentation via a level set formulation is presented. A sparse representation of both global (region-based) and local (voxel-wise) image information is embedded in a level set formulation to innovate a new cost function. Two dictionaries are build: A region-based feature dictionary and a voxel-wise dictionary. These dictionaries are learned, using the K-SVD method, from a public database of liver segmentation challenge (MICCAI-SLiver07). The learned dictionaries provide prior knowledge to the level set formulation. For the quantitative eval…
Seoul National University(首尔国立大学);Soong-sil University(崇实大学)
Objective: Herein, a neural network-based liver segmentation algorithm is proposed, and its performance was evaluated using abdominal computed tomography (CT) images. Methods: A fully convolutional network was developed to overcome the volumetric image segmentation problem. To guide a neural network to accurately delineate a target liver object, the network was deeply supervised by applying the adaptive self-supervision scheme to derive the essential contour, which acted as a complement with the global shape. The discriminative contour, shape, and deep features were internally merged for the s…
Label-Efficient Cross-Modality Generalization for Liver Segmentation in Multi-Phase MRI
Ho Chi Minh University of Science(胡志明科技大学);National Central University(国立中央大学);Carnegie Mellon University(卡内基梅隆大学);University of Houston(休斯顿大学);Northwestern University(西北大学)
Institute of Computing Technology, Chinese Academy of Sciences(中国科学院计算技术研究所);University of Chinese Academy of Sciences(中国科学院大学);University of California, Los Angeles(加利福尼亚大学洛杉矶分校);University of Southern California(南加利福尼亚大学);Lenovo Research(联想研究院);Lenovo Ltd.(联想有限公司)
Purpose: Automated liver tumor segmentation from Computed Tomography (CT) images is a necessary prerequisite in the interventions of hepatic abnormalities and surgery planning. However, accurate liver tumor segmentation remains challenging due to the large variability of tumor sizes and inhomogeneous texture. Recent advances based on Fully Convolutional Network (FCN) for medical image segmentation drew on the success of learning discriminative pyramid features. In this paper, we propose a Decoupled Pyramid Correlation Network (DPC-Net) that exploits attention mechanisms to fully leverage both …
ASLseg: Adapting SAM in the Loop for Semi-supervised Liver Tumor Segmentation
Southern University of Science and Technology(南方科技大学);The University of Hong Kong(香港大学);Jiaxing Research Institute, Southern University of Science and Technology(南方科技大学嘉兴研究院)
Barcelona Supercomputing Center (BSC)(巴塞罗那超级计算中心);Eidgenössische Technische Hochschule Zürich (ETH Zürich)(苏黎世联邦理工学院);Universitat Politècnica de Catalunya (UPC)(加泰罗尼亚理工大学)
A fully automatic technique for segmenting the liver and localizing its unhealthy tissues is a convenient tool in order to diagnose hepatic diseases and assess the response to the according treatments. In this work we propose a method to segment the liver and its lesions from Computed Tomography (CT) scans using Convolutional Neural Networks (CNNs), that have proven good results in a variety of computer vision tasks, including medical imaging. The network that segments the lesions consists of a cascaded architecture, which first focuses on the region of the liver in order to segment the lesion…
Automatic liver segmentation plays an important role in computer-aided diagnosis and treatment. Manual segmentation of organs is a difficult and tedious task and so prone to human errors. In this paper, we propose an adaptive 3D region growing with subject-specific conditions. For this aim we use the intensity distribution of most probable voxels in prior map along with location prior. We also incorporate the boundary of target organs to restrict the region growing. In order to obtain strong edges and high contrast, we propose an effective contrast enhancement algorithm to facilitate more accu…
Semi-supervised Liver Segmentation and Patch-based Fibrosis Staging with Registration-aided Multi-parametric MRI
1 Intelligent Modelling \& Analysis Group (IMA), 2 Lab for Uncertainty in Data;Decision Making (LUCID), \ of Computer Science, University of Nottingham, UK 3 Nottingham Biomedical Research Centre (BRC), \ of Medicine, University of Nottingham, UK;Intelligent Modelling \& Analysis Group (IMA), School of Computer Science, University of Nottingham, UK Lab for Uncertainty in Data;Decision Making (LUCID), School of Computer Science, University of Nottingham, UK Nottingham Biomedical Research Centre (BRC), School of Medicine, University of Nottingham, UK
First Affiliated Hospital of Zhejiang University(浙江大学医学院附属第一医院);Zhejiang University(浙江大学)
Purpose Segmentation of the liver from abdominal computed tomography (CT) image is an essential step in some computer assisted clinical interventions, such as surgery planning for living donor liver transplant (LDLT), radiotherapy and volume measurement. In this work, we develop a deep learning algorithm with graph cut refinement to automatically segment liver in CT scans. Methods The proposed method consists of two main steps: (i) simultaneously liver detection and probabilistic segmentation using 3D convolutional neural networks (CNNs); (ii) accuracy refinement of initial segmentation with g…
Medical Faculty Mannheim(曼海姆医学院);Heidelberg University(海德堡大学);Tooploox
We propose a novel procedure to improve liver and lesion segmentation from CT scans for U-Net based models. Our method extends standard segmentation pipelines to focus on higher target recall or reduction of noisy false-positive predictions, boosting overall segmentation performance. To achieve this, we include segmentation errors into a new learning process appended to the main training setup, allowing the model to find features which explain away previous errors. We evaluate this on semantically distinct architectures: cascaded two- and three-dimensional as well as combined learning setups f…
Zhejiang University(浙江大学);Stevens Institute of Technology(斯蒂文斯理工学院);Zhejiang Lab(之江实验室);Zhejiang University of Technology(浙江工业大学);Alibaba-Zhejiang University Joint Research Institute of Frontier Technologies(阿里巴巴-浙江大学前沿技术联合研究中心)
The microvascular invasion (MVI) is a major prognostic factor in hepatocellular carcinoma, which is one of the malignant tumors with the highest mortality rate. The diagnosis of MVI needs discovering the vessels that contain hepatocellular carcinoma cells and counting their number in each vessel, which depends heavily on experiences of the doctor, is largely subjective and time-consuming. However, there is no algorithm as yet tailored for the MVI detection from pathological images. This paper collects the first pathological liver image dataset containing 522 whole slide images with labels of v…
The Chinese University of Hong Kong(香港中文大学);The Hong Kong Polytechnic University(香港理工大学)
Automatic liver segmentation from CT volumes is a crucial prerequisite yet challenging task for computer-aided hepatic disease diagnosis and treatment. In this paper, we present a novel 3D deeply supervised network (3D DSN) to address this challenging task. The proposed 3D DSN takes advantage of a fully convolutional architecture which performs efficient end-to-end learning and inference. More importantly, we introduce a deep supervision mechanism during the learning process to combat potential optimization difficulties, and thus the model can acquire a much faster convergence rate and more po…
T-MPEDNet: Unveiling the Synergy of Transformer-aware Multiscale Progressive Encoder-Decoder Network with Feature Recalibration for Tumor and Liver Segmentation
Department of Computer Science and Engineering, Indian Institute of Technology (IIT) Indore, Indore 453552, India(计算机科学与工程系,印度理工学院(IIT)印尔德,印尔德453552,印度);Department of Electrical Engineering, Indian Institute of Technology (IIT) Indore, Indore 453552, India(电气工程系,印度理工学院(IIT)印尔德,印尔德453552,印度)
Graz University of Technology(格拉茨工业大学);Ulm University(乌尔姆大学);Shanghai Jiao Tong University(上海交通大学);BioTechMed-Graz(格拉茨生物科技医疗);Katharinenhospital(卡塔琳娜医院)
The manual outlining of hepatic metastasis in (US) ultrasound acquisitions from patients suffering from pancreatic cancer is common practice. However, such pure manual measurements are often very time consuming, and the results repeatedly differ between the raters. In this contribution, we study the in-depth assessment of an interactive graph-based approach for the segmentation for pancreatic metastasis in US images of the liver with two specialists in Internal Medicine. Thereby, evaluating the approach with over one hundred different acquisitions of metastases. The two physicians or the algor…
Stony Brook University(石溪大学);University of Brasília(巴西利亚大学);Emory University(埃默里大学)
An accurate steatosis quantification with pathology tissue samples is of high clinical importance. However, such pathology measurement is manually made in most clinical practices, subject to severe reader variability due to large sampling bias and poor reproducibility. Although some computerized automated methods are developed to quantify the steatosis regions, they present limited analysis capacity for high resolution whole-slide microscopy images and accurate overlapped steatosis division. In this paper, we propose a method that extracts an individual whole tissue piece at high resolution wi…
National Institutes of Health Clinical Center(美国国立卫生研究院临床中心);Ping An Insurance Company of China(中国平安保险公司)
Developing an effective liver and liver tumor segmentation model from CT scans is very important for the success of liver cancer diagnosis, surgical planning and cancer treatment. In this work, we propose a two-stage framework for 2D liver and tumor segmentation. The first stage is a coarse liver segmentation network, while the second stage is an edge enhanced network (E$^2$Net) for more accurate liver and tumor segmentation. E$^2$Net explicitly models complementary objects (liver and tumor) and their edge information within the network to preserve the organ and lesion boundaries. We introduce…
Automatic extraction of liver and tumor from CT volumes is a challenging task due to their heterogeneous and diffusive shapes. Recently, 2D and 3D deep convolutional neural networks have become popular in medical image segmentation tasks because of the utilization of large labeled datasets to learn hierarchical features. However, 3D networks have some drawbacks due to their high cost on computational resources. In this paper, we propose a 3D hybrid residual attention-aware segmentation method, named RA-UNet, to precisely extract the liver volume of interests (VOI) and segment tumors from the l…
Uncertainty-Aware Segmentation Quality Prediction via Deep Learning Bayesian Modeling: Comprehensive Evaluation and Interpretation on Skin Cancer and Liver Segmentation
BCN Medtech(BCN医学科技);Scientific and Technical Department, Sycai Technologies S.L.(Sycai技术部门)
Accurate visualization of liver tumors and their surrounding blood vessels is essential for noninvasive diagnosis and prognosis prediction of tumors. In medical image segmentation, there is still a lack of in-depth research on the simultaneous segmentation of liver tumors and peritumoral blood vessels. To this end, we collect the first liver tumor, and vessel segmentation benchmark datasets containing 52 portal vein phase computed tomography images with liver, liver tumor, and vessel annotations. In this case, we propose a 3D U-shaped Cross-Attention Network (UCA-Net) that utilizes a tailored …
Accurate liver and lesion segmentation from computed tomography (CT) images are highly demanded in clinical practice for assisting the diagnosis and assessment of hepatic tumor disease. However, automatic liver and lesion segmentation from contrast-enhanced CT volumes is extremely challenging due to the diversity in contrast, resolution, and quality of images. Previous methods based on UNet for 2D slice-by-slice or 3D volume-by-volume segmentation either lack sufficient spatial contexts or suffer from high GPU computational cost, which limits the performance. To tackle these issues, we propose…
Vanderbilt University(范德堡大学);Vanderbilt University Medical Center(范德堡大学医学中心);Wake Forest School of Medicine(维克森林大学医学院)
Manually tracing regions of interest (ROIs) within the liver is the de facto standard method for measuring liver attenuation on computed tomography (CT) in diagnosing nonalcoholic fatty liver disease (NAFLD). However, manual tracing is resource intensive. To address these limitations and to expand the availability of a quantitative CT measure of hepatic steatosis, we propose the automatic liver attenuation ROI-based measurement (ALARM) method for automated liver attenuation estimation. The ALARM method consists of two major stages: (1) deep convolutional neural network (DCNN)-based liver segme…
Technical University of Munich(慕尼黑工业大学);LMU Hospital Grosshadern(路德维希-马克西米利安-慕尼黑大学格罗斯哈德恩医院)
Automatic segmentation of the liver and hepatic lesions is an important step towards deriving quantitative biomarkers for accurate clinical diagnosis and computer-aided decision support systems. This paper presents a method to automatically segment liver and lesions in CT and MRI abdomen images using cascaded fully convolutional neural networks (CFCNs) enabling the segmentation of a large-scale medical trial or quantitative image analysis. We train and cascade two FCNs for a combined segmentation of the liver and its lesions. In the first step, we train a FCN to segment the liver as ROI input …
China University of Petroleum(中国石油大学);Qingdao Municipal Hospital(青岛市市立医院);University of Chinese Academy of Sciences(中国科学院大学)
Liver cancer is one of the most common malignant diseases in the world. Segmentation and labeling of liver tumors and blood vessels in CT images can provide convenience for doctors in liver tumor diagnosis and surgical intervention. In the past decades, many state-of-the-art medical image segmentation algorithms appeared during this period. With the development of embedded devices, embedded deployment for medical segmentation and automatic reconstruction brings prospects for future automated surgical tasks. Yet, most of the existing segmentation methods mostly care about the spatial feature co…
University of Sydney(悉尼大学);Shanghai Jiao Tong University(上海交通大学)
Automatic segmentation of liver lesions is a fundamental requirement towards the creation of computer aided diagnosis (CAD) and decision support systems (CDS). Traditional segmentation approaches depend heavily upon hand-crafted features and a priori knowledge of the user. As such, these methods are difficult to adopt within a clinical environment. Recently, deep learning methods based on fully convolutional networks (FCNs) have been successful in many segmentation problems primarily because they leverage a large labelled dataset to hierarchically learn the features that best correspond to the…
Seoul National University(首尔国立大学);Soong-sil University(崇实大学)
Accurate image segmentation of the liver is a challenging problem owing to its large shape variability and unclear boundaries. Although the applications of fully convolutional neural networks (CNNs) have shown groundbreaking results, limited studies have focused on the performance of generalization. In this study, we introduce a CNN for liver segmentation on abdominal computed tomography (CT) images that shows high generalization performance and accuracy. To improve the generalization performance, we initially propose an auto-context algorithm in a single CNN. The proposed auto-context neural …
Heidelberg University(海德堡大学);University Medical Center Mannheim(曼海姆大学医学中心)
At present, lesion segmentation is still performed manually (or semi-automatically) by medical experts. To facilitate this process, we contribute a fully-automatic lesion segmentation pipeline. This work proposes a method as a part of the LiTS (Liver Tumor Segmentation Challenge) competition for ISBI 17 and MICCAI 17 comparing methods for automatics egmentation of liver lesions in CT scans. By utilizing cascaded, densely connected 2D U-Nets and a Tversky-coefficient based loss function, our framework achieves very good shape extractions with high detection sensitivity, with competitive scores …
Hunan University of Technology and Business(湖南工商大学);Utah State University(犹他州立大学);University of Idaho(爱达荷大学)
Liver segmentation from abdominal CT images is an essential step for liver cancer computer-aided diagnosis and surgical planning. However, both the accuracy and robustness of existing liver segmentation methods cannot meet the requirements of clinical applications. In particular, for the common clinical cases where the liver tissue contains major pathology, current segmentation methods show poor performance. In this paper, we propose a novel low-rank tensor decomposition (LRTD) based multi-atlas segmentation (MAS) framework that achieves accurate and robust pathological liver segmentation of C…
Institute of Computing Technology, Chinese Academy of Sciences(中国科学院计算技术研究所);University of Chinese Academy of Sciences(中国科学院大学);Lenovo Research(联想研究院)
Liver tumor segmentation plays an important role in hepatocellular carcinoma diagnosis and surgical planning. In this paper, we propose a novel Semantic Feature Attention Network (SFAN) for liver tumor segmentation from Computed Tomography (CT) volumes, which exploits the impact of both low-level and high-level features. In the SFAN, a Semantic Attention Transmission (SAT) module is designed to select discriminative low-level localization details with the guidance of neighboring high-level semantic information. Furthermore, a Global Context Attention (GCA) module is proposed to effectively fus…
Technical University of Munich(慕尼黑工业大学);University of Zurich(苏黎世大学);Ecole Polytechnique de Montréal(蒙特利尔理工学院);Tel-Aviv University(特拉维夫大学);Imperial College London(帝国理工学院);Hebrew University of Jerusalem(希伯来大学);Radboud University Medical Center(拉德堡德大学医学中心);The University of Montréal Hospital Research Centre(蒙特利尔大学医院研究中心);LMU Munich(慕尼黑大学)
In this work, we report the set-up and results of the Liver Tumor Segmentation Benchmark (LiTS), which was organized in conjunction with the IEEE International Symposium on Biomedical Imaging (ISBI) 2017 and the International Conferences on Medical Image Computing and Computer-Assisted Intervention (MICCAI) 2017 and 2018. The image dataset is diverse and contains primary and secondary tumors with varied sizes and appearances with various lesion-to-background levels (hyper-/hypo-dense), created in collaboration with seven hospitals and research institutions. Seventy-five submitted liver and liv…
University of Innsbruck(因斯布鲁克大学);Medical University of Innsbruck(因斯布鲁克医科大学)
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults, and the most common cause of death of people suffering from cirrhosis. The segmentation of liver lesions in CT images allows assessment of tumor load, treatment planning, prognosis and monitoring of treatment response. Manual segmentation is a very time-consuming task and in many cases, prone to inaccuracies and automatic tools for tumor detection and segmentation are desirable. In this paper, we compare two network architectures, one that is composed of one neural network and manages the segmentation tas…
Stanford University(斯坦福大学);University of California, San Diego Medical Center(加州大学圣地亚哥医学中心)
We propose a novel method, the adaptive local window, for improving level set segmentation technique. The window is estimated separately for each contour point, over iterations of the segmentation process, and for each individual object. Our method considers the object scale, the spatial texture, and changes of the energy functional over iterations. Global and local statistics are considered by calculating several gray level co-occurrence matrices. We demonstrate the capabilities of the method in the domain of medical imaging for segmenting 233 images with liver lesions. To illustrate the stre…
Transfer learning and joint learning approaches are extensively used to improve the performance of Convolutional Neural Networks (CNNs). In medical imaging applications in which the target dataset is typically very small, transfer learning improves feature learning while joint learning has shown effectiveness in improving the network's generalization and robustness. In this work, we study the combination of these two approaches for the problem of liver lesion segmentation and classification. For this purpose, 332 abdominal CT slices containing lesion segmentation and classification of three le…
University of Science and Technology of China(中国科学技术大学);Rensselaer Polytechnic Institute(伦斯勒理工学院)
Liver lesion segmentation is a difficult yet critical task for medical image analysis. Recently, deep learning based image segmentation methods have achieved promising performance, which can be divided into three categories: 2D, 2.5D and 3D, based on the dimensionality of the models. However, 2.5D and 3D methods can have very high complexity and 2D methods may not perform satisfactorily. To obtain competitive performance with low complexity, in this paper, we propose a Feature-fusion Encoder-Decoder Network (FED-Net) based 2D segmentation model to tackle the challenging problem of liver lesion…
Primary tumors have a high likelihood of developing metastases in the liver and early detection of these metastases is crucial for patient outcome. We propose a method based on convolutional neural networks (CNN) to detect liver metastases. First, the liver was automatically segmented using the six phases of abdominal dynamic contrast enhanced (DCE) MR images. Next, DCE-MR and diffusion weighted (DW) MR images are used for metastases detection within the liver mask. The liver segmentations have a median Dice similarity coefficient of 0.95 compared with manual annotations. The metastases detect…
Artificial Intelligence-Enhanced Couinaud Segmentation for Precision Liver Cancer Therapy
Stanford University(斯坦福大学);University of Southern California(南加州大学);Massachusetts General Hospital(麻省总医院);Harvard Medical School(哈佛医学院);Wake Forest University(维克森林大学);Shandong Provincial Hospital Affiliated to Shandong First Medical University(山东第一医科大学附属山东省立医院);Shandong First Medical University(山东第一医科大学)
Philips Research Paris(飞利浦巴黎研究院);Hospices Civils de Lyon(里昂民用医院)
We address the problem of multimodal liver segmentation in paired but unregistered T1 and T2-weighted MR images. We compare several strategies described in the literature, with or without multi-task training, with or without pre-registration. We also compare different loss functions (cross-entropy, Dice loss, and three adversarial losses). All methods achieved comparable performances with the exception of a multi-task setting that performs both segmentations at once, which performed poorly.
Trustworthy Multi-phase Liver Tumor Segmentation via Evidence-based Uncertainty
Southeast University(东南大学);the First Affiliated Hospital, Zhejiang University School of Medicine(浙江大学医学院附属第一医院);Zhongda Hospital, School of Medicine, Southeast University(东南大学医学院附属中大医院)
Multi-modal Liver Segmentation and Fibrosis Staging Using Real-world MRI Images
Multiscale X-ray Imaging (MXI) Lab, Department of Mechanical Engineering, University College London(多尺度X射线成像实验室,机械工程系,伦敦大学学院);Centre for Clinical Brain Sciences, University of Edinburgh(临床脑科学中心,爱丁堡大学);MRC Weatherall Institute of Molecular Medicine, University of Oxford(MRC韦伯尔分子医学研究所,牛津大学)
SRMA-Mamba: Spatial Reverse Mamba Attention Network for Pathological Liver Segmentation in MRI Volumes
Chongqing University of Posts and Telecommunications(重庆邮电大学);Biomedical Perception & Intelligence Lab, University of South Dakota(南达科他大学生物医学感知与智能实验室);Aalto University(阿尔托大学);Malaviya National Institute of Technology Jaipur(马拉维亚国家理工学院斋浦尔分校);Machine & Hybrid Intelligence Lab, Northwestern University(西北大学机器与混合智能实验室)
Ecole Polytechnique Montréal(蒙特利尔理工学院);CHU Sainte-Justine Hospital Research Center(圣贾斯汀儿童医院研究中心);University of Montreal(蒙特利尔大学)
The early detection, diagnosis and monitoring of liver cancer progression can be achieved with the precise delineation of metastatic tumours. However, accurate automated segmentation remains challenging due to the presence of noise, inhomogeneity and the high appearance variability of malignant tissue. In this paper, we propose an unsupervised metastatic liver tumour segmentation framework using a machine learning approach based on discriminant Grassmannian manifolds which learns the appearance of tumours with respect to normal tissue. First, the framework learns within-class and between-class…
Washington State University(华盛顿州立大学);M.D. Anderson Cancer Center, University of Texas(德克萨斯大学MD安德森癌症中心)
Tumor detection in biomedical imaging is a time-consuming process for medical professionals and is not without errors. Thus in recent decades, researchers have developed algorithmic techniques for image processing using a wide variety of mathematical methods, such as statistical modeling, variational techniques, and machine learning. In this paper, we propose a semi-automatic method for liver segmentation of 2D CT scans into three labels denoting healthy, vessel, or tumor tissue based on graph cuts. First, we create a feature vector for each pixel in a novel way that consists of the 59 intensi…
Emory University(埃默里大学);Stony Brook University(石溪大学);Georgia State University(佐治亚州立大学)
Liver steatosis is known as the abnormal accumulation of lipids within cells. An accurate quantification of steatosis area within the liver histopathological microscopy images plays an important role in liver disease diagnosis and trans-plantation assessment. Such a quantification analysis often requires a precise steatosis segmentation that is challenging due to abundant presence of highly overlapped steatosis droplets. In this paper, a deep learning model Mask-RCNN is used to segment the steatosis droplets in clumps. Extended from Faster R-CNN, Mask-RCNN can predict object masks in addition …