Automatic segmentation of medical images is among most demanded works in the medical information field since it saves time of the experts in the field and avoids human error factors. In this work, a method based on Conditional Adversarial Networks and Fully Convolutional Networks is proposed for the automatic segmentation of the liver MRIs. The proposed method, without any post-processing, is achieved the second place in the SIU Liver Segmentation Challenge 2018, data of which is provided by Dokuz Eylül University. In this paper, some improvements for the post-processing step are also proposed and it is shown that with these additions, the method outperforms other baseline methods.
Automatic liver segmentation in 3D medical images is essential in many clinical applications, such as pathological diagnosis of hepatic diseases, surgical planning, and postoperative assessment. However, it is still a very challenging task due to the complex background, fuzzy boundary, and various appearance of liver. In this paper, we propose an automatic and efficient algorithm to segment liver from 3D CT volumes. A deep image-to-image network (DI2IN) is first deployed to generate the liver segmentation, employing a convolutional encoder-decoder architecture combined with multi-level feature…
Shandong Normal University(山东师范大学);Western University(韦仕敦大学)
Simultaneous segmentation and detection of liver tumors (hemangioma and hepatocellular carcinoma (HCC)) by using multi-modality non-contrast magnetic resonance imaging (NCMRI) are crucial for the clinical diagnosis. However, it is still a challenging task due to: (1) the HCC information on NCMRI is invisible or insufficient makes extraction of liver tumors feature difficult; (2) diverse imaging characteristics in multi-modality NCMRI causes feature fusion and selection difficult; (3) no specific information between hemangioma and HCC on NCMRI cause liver tumors detection difficult. In this stu…
Technical University of Munich(慕尼黑工业大学);LMU Hospital Grosshadern(路德维希-马克西米利安-慕尼黑大学格罗斯哈德恩医院)
Automatic segmentation of the liver and hepatic lesions is an important step towards deriving quantitative biomarkers for accurate clinical diagnosis and computer-aided decision support systems. This paper presents a method to automatically segment liver and lesions in CT and MRI abdomen images using cascaded fully convolutional neural networks (CFCNs) enabling the segmentation of a large-scale medical trial or quantitative image analysis. We train and cascade two FCNs for a combined segmentation of the liver and its lesions. In the first step, we train a FCN to segment the liver as ROI input …
Technical University of Munich(慕尼黑工业大学);University of California, Irvine(加利福尼亚大学尔湾分校)
The segmentation of liver lesions is crucial for detection, diagnosis and monitoring progression of liver cancer. However, design of accurate automated methods remains challenging due to high noise in CT scans, low contrast between liver and lesions, as well as large lesion variability. We propose a 3D automatic, unsupervised method for liver lesions segmentation using a phase separation approach. It is assumed that liver is a mixture of two phases: healthy liver and lesions, represented by different image intensities polluted by noise. The Cahn-Hilliard equation is used to remove the noise an…
SPARS: Self-Play Adversarial Reinforcement Learning for Segmentation of Liver Tumours
Department of Medical Physics and Biomedical Engineering, University College London(医学物理与生物医学工程系,伦敦大学学院);UCL Hawkes Institute, University College London(UCL哈维斯研究所,伦敦大学学院)
Sun Yat-sen University(中山大学);The First Affiliated Hospital, Sun Yat-sen University(中山大学附属第一医院);Infervision Inc.(推想医疗科技股份有限公司)
Hepatocellular carcinoma (HCC) is the second most frequent cause of malignancy-related death and is one of the diseases with the highest incidence in the world. Because the liver is the only organ in the human body that is supplied by two major vessels: the hepatic artery and the portal vein, various types of malignant tumors can spread from other organs to the liver. And due to the liver masses' heterogeneous and diffusive shape, the tumor lesions are very difficult to be recognized, thus automatic lesion detection is necessary for the doctors with huge workloads. To assist doctors, this work…
James Cook University(詹姆斯·库克大学);Mahidol University(玛希隆大学);University of Bremen(不来梅大学)
Automatic segmentation of hepatic lesions in computed tomography (CT) images is a challenging task to perform due to heterogeneous, diffusive shape of tumors and complex background. To address the problem more and more researchers rely on assistance of deep convolutional neural networks (CNN) with 2D or 3D type architecture that have proven to be effective in a wide range of computer vision tasks, including medical image processing. In this technical report, we carry out research focused on more careful approach to the process of learning rather than on complex architecture of the CNN. We have…
Philips Research Paris(飞利浦巴黎研究院);Hospices Civils de Lyon(里昂民用医院)
We address the problem of multimodal liver segmentation in paired but unregistered T1 and T2-weighted MR images. We compare several strategies described in the literature, with or without multi-task training, with or without pre-registration. We also compare different loss functions (cross-entropy, Dice loss, and three adversarial losses). All methods achieved comparable performances with the exception of a multi-task setting that performs both segmentations at once, which performed poorly.
Barcelona Supercomputing Center (BSC)(巴塞罗那超级计算中心);Eidgenössische Technische Hochschule Zürich (ETH Zürich)(苏黎世联邦理工学院);Universitat Politècnica de Catalunya (UPC)(加泰罗尼亚理工大学)
A fully automatic technique for segmenting the liver and localizing its unhealthy tissues is a convenient tool in order to diagnose hepatic diseases and assess the response to the according treatments. In this work we propose a method to segment the liver and its lesions from Computed Tomography (CT) scans using Convolutional Neural Networks (CNNs), that have proven good results in a variety of computer vision tasks, including medical imaging. The network that segments the lesions consists of a cascaded architecture, which first focuses on the region of the liver in order to segment the lesion…
Automatic extraction of liver and tumor from CT volumes is a challenging task due to their heterogeneous and diffusive shapes. Recently, 2D and 3D deep convolutional neural networks have become popular in medical image segmentation tasks because of the utilization of large labeled datasets to learn hierarchical features. However, 3D networks have some drawbacks due to their high cost on computational resources. In this paper, we propose a 3D hybrid residual attention-aware segmentation method, named RA-UNet, to precisely extract the liver volume of interests (VOI) and segment tumors from the l…
Eastern Hepatobiliary Surgery Hospital(东方肝胆外科医院);Ping An Technology(平安科技);Georgia Institute of Technology(佐治亚理工学院);PAII Inc.(PAII公司)
Objectives: to propose a fully-automatic computer-aided diagnosis (CAD) solution for liver lesion characterization, with uncertainty estimation. Methods: we enrolled 400 patients who had either liver resection or a biopsy and was diagnosed with either hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma, or secondary metastasis, from 2006 to 2019. Each patient was scanned with T1WI, T2WI, T1WI venous phase (T2WI-V), T1WI arterial phase (T1WI-A), and DWI MRI sequences. We propose a fully-automatic deep CAD pipeline that localizes lesions from 3D MRI studies using key-slice parsing an…
Rongcheng College, Harbin University of Science and Technology(哈尔滨理工大学荣成学院);Harbin University of Science and Technology(哈尔滨理工大学);Hunan University of Technology and Business(湖南工商大学)
Background and objective: In this paper, a modified U-Net based framework is presented, which leverages techniques from Squeeze-and-Excitation (SE) block, Atrous Spatial Pyramid Pooling (ASPP) and residual learning for accurate and robust liver CT segmentation, and the effectiveness of the proposed method was tested on two public datasets LiTS17 and SLiver07. Methods: A new network architecture called SAR-U-Net was designed. Firstly, the SE block is introduced to adaptively extract image features after each convolution in the U-Net encoder, while suppressing irrelevant regions, and highlightin…
A Digital Pathology Resource for Liver Cancer Quantification with Datasets, Benchmarks, and Tools
Department of Pathology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China(北京清华长庚医院病理科,临床医学学院,清华大学医学院,清华大学,北京,中国);Shenzhen International Graduate School, Tsinghua University, Shenzhen, China(深圳国际研究生院,清华大学,深圳,中国)
University of sousse(苏塞大学);University of Monastir(莫纳斯提尔大学)
The aim of this work is to develop a method for automatic segmentation of the liver based on a priori knowledge of the image, such as location and shape of the liver.
Mansoura University(曼苏尔大学);South Valley University(南河谷大学);Higher Institute of Engineering and Technology(高等工程技术学院)
The liver is one of the most critical metabolic organs in vertebrates due to its vital functions in the human body, such as detoxification of the blood from waste products and medications. Liver diseases due to liver tumors are one of the most common mortality reasons around the globe. Hence, detecting liver tumors in the early stages of tumor development is highly required as a critical part of medical treatment. Many imaging modalities can be used as aiding tools to detect liver tumors. Computed tomography (CT) is the most used imaging modality for soft tissue organs such as the liver. This …
Accurate segmentation of the liver is a prerequisite for the diagnosis of disease. Automated segmentation is an important application of computer-aided detection and diagnosis of liver disease. In recent years, automated processing of medical images has gained breakthroughs. However, the low contrast of abdominal scan CT images and the complexity of liver morphology make accurate automatic segmentation challenging. In this paper, we propose RA V-Net, which is an improved medical image automatic segmentation model based on U-Net. It has the following three main innovations. CofRes Module (Compo…
Yokohama City University Medical Center(横滨市立大学医学中心)
We present a fully automatic method employing convolutional neural networks based on the 2D U-net architecture and random forest classifier to solve the automatic liver lesion segmentation problem of the ISBI 2017 Liver Tumor Segmentation Challenge (LiTS). In order to constrain the ROI in which the tumors could be located, a liver segmentation is performed first. For the organ segmentation, an ensemble of convolutional networks is trained to segment a liver using a set of 179 liver CT datasets from liver surgery planning. Inside of the liver ROI a neural network, trained using 127 challenge tr…
Automatic segmentation of liver tumors in medical images is crucial for the computer-aided diagnosis and therapy. It is a challenging task, since the tumors are notoriously small against the background voxels. This paper proposes a new three-stage curriculum learning approach for training deep networks to tackle this small object segmentation problem. The learning in the first stage is performed on the whole input to obtain an initial deep network for tumor segmenta-tion. Then the second stage of learning focuses the strength-ening of tumor specific features by continuing training the network …
Indian Institute of Technology, Madras(马德拉斯印度理工学院)
In this paper we propose a fully automatic 2-stage cascaded approach for segmentation of liver and its tumors in CT (Computed Tomography) images using densely connected fully convolutional neural network (DenseNet). We independently train liver and tumor segmentation models and cascade them for a combined segmentation of the liver and its tumor. The first stage involves segmentation of liver and the second stage uses the first stage's segmentation results for localization of liver and henceforth tumor segmentations inside liver region. The liver model was trained on the down-sampled axial slic…
Tel Aviv University(特拉维夫大学);The Chaim Sheba Medical Center(夏姆谢巴医疗中心);Bar-Ilan University(巴伊兰大学)
Deep learning methods, and in particular convolutional neural networks (CNNs), have led to an enormous breakthrough in a wide range of computer vision tasks, primarily by using large-scale annotated datasets. However, obtaining such datasets in the medical domain remains a challenge. In this paper, we present methods for generating synthetic medical images using recently presented deep learning Generative Adversarial Networks (GANs). Furthermore, we show that generated medical images can be used for synthetic data augmentation, and improve the performance of CNN for medical image classificatio…
Automatic segmentation of liver and its tumors is an essential step for extracting quantitative imaging biomarkers for accurate tumor detection, diagnosis, prognosis and assessment of tumor response to treatment. MICCAI 2017 Liver Tumor Segmentation Challenge (LiTS) provides a common platform for comparing different automatic algorithms on contrast-enhanced abdominal CT images in tasks including 1) liver segmentation, 2) liver tumor segmentation, and 3) tumor burden estimation. We participate this challenge by developing a hierarchical framework based on deep fully convolutional-deconvolutiona…
Liver lesion segmentation is an important step for liver cancer diagnosis, treatment planning and treatment evaluation. LiTS (Liver Tumor Segmentation Challenge) provides a common testbed for comparing different automatic liver lesion segmentation methods. We participate in this challenge by developing a deep convolutional neural network (DCNN) method. The particular DCNN model works in 2.5D in that it takes a stack of adjacent slices as input and produces the segmentation map corresponding to the center slice. The model has 32 layers in total and makes use of both long range concatenation con…
PAII Inc.(PAII公司);The University of Texas at Arlington(德克萨斯大学阿灵顿分校);Chang Gung Memorial Hospital(长庚纪念医院);PingAn Technology(平安科技)
In medical imaging, organ/pathology segmentation models trained on current publicly available and fully-annotated datasets usually do not well-represent the heterogeneous modalities, phases, pathologies, and clinical scenarios encountered in real environments. On the other hand, there are tremendous amounts of unlabelled patient imaging scans stored by many modern clinical centers. In this work, we present a novel segmentation strategy, co-heterogenous and adaptive segmentation (CHASe), which only requires a small labeled cohort of single phase imaging data to adapt to any unlabeled cohort of …
We propose a new generative adversarial architecture to mitigate imbalance data problem in medical image semantic segmentation where the majority of pixels belongs to a healthy region and few belong to lesion or non-health region. A model trained with imbalanced data tends to bias toward healthy data which is not desired in clinical applications and predicted outputs by these networks have high precision and low sensitivity. We propose a new conditional generative refinement network with three components: a generative, a discriminative, and a refinement network to mitigate unbalanced data prob…
Technische Universität München(慕尼黑工业大学);LMU Hospital Grosshadern(LMU格罗斯哈德恩医院)
Automatic segmentation of the liver and its lesion is an important step towards deriving quantitative biomarkers for accurate clinical diagnosis and computer-aided decision support systems. This paper presents a method to automatically segment liver and lesions in CT abdomen images using cascaded fully convolutional neural networks (CFCNs) and dense 3D conditional random fields (CRFs). We train and cascade two FCNs for a combined segmentation of the liver and its lesions. In the first step, we train a FCN to segment the liver as ROI input for a second FCN. The second FCN solely segments lesion…
Automatic segmentation of abdomen organs using medical imaging has many potential applications in clinical workflows. Recently, the state-of-the-art performance for organ segmentation has been achieved by deep learning models, i.e., convolutional neural network (CNN). However, it is challenging to train the conventional CNN-based segmentation models that aware of the shape and topology of organs. In this work, we tackle this problem by introducing a novel end-to-end shape learning architecture -- organ point-network. It takes deep learning features as inputs and generates organ shape represent…
Localization of anatomical structures is a prerequisite for many tasks in medical image analysis. We propose a method for automatic localization of one or more anatomical structures in 3D medical images through detection of their presence in 2D image slices using a convolutional neural network (ConvNet). A single ConvNet is trained to detect presence of the anatomical structure of interest in axial, coronal, and sagittal slices extracted from a 3D image. To allow the ConvNet to analyze slices of different sizes, spatial pyramid pooling is applied. After detection, 3D bounding boxes are created…
Zhejiang University(浙江大学);The First Affiliated Hospital, Zhejiang University School of Medicine(浙江大学医学院附属第一医院)
Accurate segmentation for medical images is important for clinical diagnosis. Existing automatic segmentation methods are mainly based on fully supervised learning and have an extremely high demand for precise annotations, which are very costly and time-consuming to obtain. To address this problem, we proposed an automatic CT segmentation method based on weakly supervised learning, by which one could train an accurate segmentation model only with weak annotations in the form of bounding boxes. The proposed method is composed of two steps: 1) generating pseudo masks with bounding box annotation…
SIAT, Chinese Academy of Sciences(中国科学院深圳先进技术研究院);The Chinese University of Hong Kong(香港中文大学)
Purpose: Segmentation of liver vessels from CT images is indispensable prior to surgical planning and aroused broad range of interests in the medical image analysis community. Due to the complex structure and low contrast background, automatic liver vessel segmentation remains particularly challenging. Most of the related researches adopt FCN, U-net, and V-net variants as a backbone. However, these methods mainly focus on capturing multi-scale local features which may produce misclassified voxels due to the convolutional operator's limited locality reception field. Methods: We propose a robust…
University of Sydney(悉尼大学);Shanghai Jiao Tong University(上海交通大学)
Automatic segmentation of liver lesions is a fundamental requirement towards the creation of computer aided diagnosis (CAD) and decision support systems (CDS). Traditional segmentation approaches depend heavily upon hand-crafted features and a priori knowledge of the user. As such, these methods are difficult to adopt within a clinical environment. Recently, deep learning methods based on fully convolutional networks (FCNs) have been successful in many segmentation problems primarily because they leverage a large labelled dataset to hierarchically learn the features that best correspond to the…
First Affiliated Hospital of Zhejiang University(浙江大学医学院附属第一医院);Zhejiang University(浙江大学)
Purpose Segmentation of the liver from abdominal computed tomography (CT) image is an essential step in some computer assisted clinical interventions, such as surgery planning for living donor liver transplant (LDLT), radiotherapy and volume measurement. In this work, we develop a deep learning algorithm with graph cut refinement to automatically segment liver in CT scans. Methods The proposed method consists of two main steps: (i) simultaneously liver detection and probabilistic segmentation using 3D convolutional neural networks (CNNs); (ii) accuracy refinement of initial segmentation with g…
Leibniz University Hannover(汉诺威莱布尼茨大学);TU Dresden(德累斯顿工业大学)
In this paper, a novel framework for automated liver segmentation via a level set formulation is presented. A sparse representation of both global (region-based) and local (voxel-wise) image information is embedded in a level set formulation to innovate a new cost function. Two dictionaries are build: A region-based feature dictionary and a voxel-wise dictionary. These dictionaries are learned, using the K-SVD method, from a public database of liver segmentation challenge (MICCAI-SLiver07). The learned dictionaries provide prior knowledge to the level set formulation. For the quantitative eval…
Liver segmentation on images acquired using computed tomography (CT) and magnetic resonance imaging (MRI) plays an important role in clinical management of liver diseases. Compared to MRI, CT images of liver are more abundant and readily available. However, MRI can provide richer quantitative information of the liver compared to CT. Thus, it is desirable to achieve unsupervised domain adaptation for transferring the learned knowledge from the source domain containing labeled CT images to the target domain containing unlabeled MR images. In this work, we report a novel unsupervised domain adapt…
The Chinese University of Hong Kong(香港中文大学);The Hong Kong Polytechnic University(香港理工大学)
Automatic liver segmentation from CT volumes is a crucial prerequisite yet challenging task for computer-aided hepatic disease diagnosis and treatment. In this paper, we present a novel 3D deeply supervised network (3D DSN) to address this challenging task. The proposed 3D DSN takes advantage of a fully convolutional architecture which performs efficient end-to-end learning and inference. More importantly, we introduce a deep supervision mechanism during the learning process to combat potential optimization difficulties, and thus the model can acquire a much faster convergence rate and more po…
Deep Learning-Based Automatic Delineation of Liver Domes in kV Triggered Images for Online Breath-hold Reproducibility Verification of Liver Stereotactic Body Radiation Therapy
Cleveland Clinic Foundation(克利夫兰医学中心);Case Western Reserve University(凯斯西储大学)
Vanderbilt University(范德堡大学);Vanderbilt University Medical Center(范德堡大学医学中心);Wake Forest School of Medicine(维克森林大学医学院)
Manually tracing regions of interest (ROIs) within the liver is the de facto standard method for measuring liver attenuation on computed tomography (CT) in diagnosing nonalcoholic fatty liver disease (NAFLD). However, manual tracing is resource intensive. To address these limitations and to expand the availability of a quantitative CT measure of hepatic steatosis, we propose the automatic liver attenuation ROI-based measurement (ALARM) method for automated liver attenuation estimation. The ALARM method consists of two major stages: (1) deep convolutional neural network (DCNN)-based liver segme…
Lesion synthesis received much attention with the rise of efficient generative models for augmenting training data, drawing lesion evolution scenarios, or aiding expert training. The quality and diversity of synthesized data are highly dependent on the annotated data used to train the models, which not rarely struggle to derive very different yet realistic samples from the training ones. That adds an inherent bias to lesion segmentation algorithms and limits synthesizing lesion evolution scenarios efficiently. This paper presents a method for decoupling shape and density for liver lesion synth…
Rutgers University(罗格斯大学);SenseBrain;Shanghai AI Laboratory(上海人工智能实验室);Centre for Perceptual and Interactive Intelligence(感知与交互智能中心)
Data augmentation has proved extremely useful by increasing training data variance to alleviate overfitting and improve deep neural networks' generalization performance. In medical image analysis, a well-designed augmentation policy usually requires much expert knowledge and is difficult to generalize to multiple tasks due to the vast discrepancies among pixel intensities, image appearances, and object shapes in different medical tasks. To automate medical data augmentation, we propose a regularized adversarial training framework via two min-max objectives and three differentiable augmentation…
Institute of Fundamental Technological Research, Polish Academy of Sciences(波兰科学院基础技术研究所);Medical University of Warsaw(华沙医科大学)
Convolutional neural networks (CNNs) have achieved remarkable success in medical image analysis tasks. In ultrasound (US) imaging, CNNs have been applied to object classification, image reconstruction and tissue characterization. However, CNNs can be vulnerable to adversarial attacks, even small perturbations applied to input data may significantly affect model performance and result in wrong output. In this work, we devise a novel adversarial attack, specific to ultrasound (US) imaging. US images are reconstructed based on radio-frequency signals. Since the appearance of US images depends on …
Heidelberg University(海德堡大学);University Medical Center Mannheim(曼海姆大学医学中心)
At present, lesion segmentation is still performed manually (or semi-automatically) by medical experts. To facilitate this process, we contribute a fully-automatic lesion segmentation pipeline. This work proposes a method as a part of the LiTS (Liver Tumor Segmentation Challenge) competition for ISBI 17 and MICCAI 17 comparing methods for automatics egmentation of liver lesions in CT scans. By utilizing cascaded, densely connected 2D U-Nets and a Tversky-coefficient based loss function, our framework achieves very good shape extractions with high detection sensitivity, with competitive scores …
Emory University(埃默里大学);Johns Hopkins University(约翰斯·霍普金斯大学);Memorial Sloan Kettering Cancer Center(纪念斯隆·凯特琳癌症中心)
In this work, we propose an adversarial attack-based data augmentation method to improve the deep-learning-based segmentation algorithm for the delineation of Organs-At-Risk (OAR) in abdominal Computed Tomography (CT) to facilitate radiation therapy. We introduce Adversarial Feature Attack for Medical Image (AFA-MI) augmentation, which forces the segmentation network to learn out-of-distribution statistics and improve generalization and robustness to noises. AFA-MI augmentation consists of three steps: 1) generate adversarial noises by Fast Gradient Sign Method (FGSM) on the intermediate featu…
Automated liver segmentation from radiology scans (CT, MRI) can improve surgery and therapy planning and follow-up assessment in addition to conventional use for diagnosis and prognosis. Although convolutional neural networks (CNNs) have become the standard image segmentation tasks, more recently this has started to change towards Transformers based architectures because Transformers are taking advantage of capturing long range dependence modeling capability in signals, so called attention mechanism. In this study, we propose a new segmentation approach using a hybrid approach combining the Tr…
University of Science and Technology of China(中国科学技术大学);Rensselaer Polytechnic Institute(伦斯勒理工学院)
Liver lesion segmentation is a difficult yet critical task for medical image analysis. Recently, deep learning based image segmentation methods have achieved promising performance, which can be divided into three categories: 2D, 2.5D and 3D, based on the dimensionality of the models. However, 2.5D and 3D methods can have very high complexity and 2D methods may not perform satisfactorily. To obtain competitive performance with low complexity, in this paper, we propose a Feature-fusion Encoder-Decoder Network (FED-Net) based 2D segmentation model to tackle the challenging problem of liver lesion…
State Budget-Funded Health Care Institution of the City of Moscow “Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department”(莫斯科市卫生部门下属的莫斯科市国立预算资助医疗机构“诊断与远程医疗技术研究与实践临床中心”);Federal State Budgetary Scientific Institution “Russian Scientific Center of Surgery named after Academician B.V. Petrovsky”(俄罗斯联邦国立预算科研机构“以B.V.彼得罗夫斯基院士命名的俄罗斯外科科学中心”);Federal Research Center “Computer Science and Control” of Russian Academy of Sciences(俄罗斯科学院“计算机科学与控制”联邦研究中心)
This study proposes an automatic technique for liver segmentation in computed tomography (CT) images. Localization of the liver volume is based on the correlation with an optimized set of liver templates developed by the authors that allows clear geometric interpretation. Radiodensity values are calculated based on the boundaries of the segmented liver, which allows identifying liver abnormalities. The performance of the technique was evaluated on 700 CT images from dataset of the Unified Radiological Information System (URIS) of Moscow. Despite the decrease in accuracy, the technique is appli…
University of Georgia(佐治亚大学);Zhongnan Hospital of Wuhan University(武汉大学中南医院);Shanghai Jiao Tong University(上海交通大学)
In this paper we consider the problem of unsupervised anomaly segmentation in medical images, which has attracted increasing attention in recent years due to the expensive pixel-level annotations from experts and the existence of a large amount of unannotated normal and abnormal image scans. We introduce a segmentation network that utilizes adversarial learning to partition an image into two cuts, with one of them falling into a reference distribution provided by the user. This Adversarial-based Selective Cutting network (ASC-Net) bridges the two domains of cluster-based deep segmentation and …
Hunan University of Technology and Business(湖南工商大学);Utah State University(犹他州立大学);University of Idaho(爱达荷大学)
Liver segmentation from abdominal CT images is an essential step for liver cancer computer-aided diagnosis and surgical planning. However, both the accuracy and robustness of existing liver segmentation methods cannot meet the requirements of clinical applications. In particular, for the common clinical cases where the liver tissue contains major pathology, current segmentation methods show poor performance. In this paper, we propose a novel low-rank tensor decomposition (LRTD) based multi-atlas segmentation (MAS) framework that achieves accurate and robust pathological liver segmentation of C…
Shenzhen Research Institute of Big Data, the Chinese University of Hong Kong(香港中文大学深圳大数据研究院);Huazhong University of Science and Technology(华中科技大学);Shenzhen Third People’s Hospital(深圳市第三人民医院)
With the development of radiomics, noninvasive diagnosis like ultrasound (US) imaging plays a very important role in automatic liver fibrosis diagnosis (ALFD). Due to the noisy data, expensive annotations of US images, the application of Artificial Intelligence (AI) assisting approaches encounters a bottleneck. Besides, the use of mono-modal US data limits the further improve of the classification results. In this work, we innovatively propose a multi-modal fusion network with active learning (MMFN-AL) for ALFD to exploit the information of multiple modalities, eliminate the noisy data and red…
School of Automation, Harbin University of Science and Technology(哈尔滨理工大学自动化学院);Rongcheng College, Harbin University of Science and Technology(哈尔滨理工大学荣成学院)
Purpose: This paper proposes a new network framework called EAR-U-Net, which leverages EfficientNetB4, attention gate, and residual learning techniques to achieve automatic and accurate liver segmentation. Methods: The proposed method is based on the U-Net framework. First, we use EfficientNetB4 as the encoder to extract more feature information during the encoding stage. Then, an attention gate is introduced in the skip connection to eliminate irrelevant regions and highlight features of a specific segmentation task. Finally, to alleviate the problem of gradient vanishment, we replace the tra…
Isfahan University of Technology(伊斯法罕理工大学);University of Michigan(密歇根大学)
The need for CT scan analysis is growing for pre-diagnosis and therapy of abdominal organs. Automatic organ segmentation of abdominal CT scan can help radiologists analyze the scans faster and segment organ images with fewer errors. However, existing methods are not efficient enough to perform the segmentation process for victims of accidents and emergencies situations. In this paper we propose an efficient liver segmentation with our 3D to 2D fully connected network (3D-2D-FCN). The segmented mask is enhanced by means of conditional random field on the organ's border. Consequently, we segment…
Ankara University(安卡拉大学);Turkish Aerospace(土耳其航空航天工业公司);Akgun R&D Center(Akgun研发中心)
Medical imaging has been employed to support medical diagnosis and treatment. It may also provide crucial information to surgeons to facilitate optimal surgical preplanning and perioperative management. Essentially, semi-automatic organ and tumor segmentation has been studied by many researchers. Recently, with the development of Deep Learning (DL) algorithms, automatic organ segmentation has been gathered lots of attention from the researchers. This paper addresses to propose the most efficient DL architectures for Liver segmentation by adapting and comparing state-of-the-art DL frameworks, s…
Adversarial Multi-Task Learning for Liver Tumor Segmentation, Dynamic Enhancement Regression, and Classification
Department of Computer Science, Toronto Metropolitan University(计算机科学系,多伦多 Metropolitan 大学);Department of Computer Science, Hanyang University(计算机科学系,翰阳大学)
University of Science and Technology of China(中国科学技术大学);University of Miami(迈阿密大学);the First Affiliated Hospital of USTC(中国科学技术大学附属第一医院)
Automatic deep learning segmentation models has been shown to improve both the segmentation efficiency and the accuracy. However, training a robust segmentation model requires considerably large labeled training samples, which may be impractical. This study aimed to develop a deep learning framework for generating synthetic lesions that can be used to enhance network training. The lesion synthesis network is a modified generative adversarial network (GAN). Specifically, we innovated a partial convolution strategy to construct an Unet-like generator. The discriminator is designed using Wasserst…
Robustly Optimized Deep Feature Decoupling Network for Fatty Liver Diseases Detection
School of Computing and Artificial Intelligence, Southwest Jiaotong University(西南交通大学计算机与人工智能学院);Department of Computer and Information Technology, Purdue University(普渡大学计算机与信息技术系);School of Computer Science, Chengdu University of Information Technology(成都信息工程大学计算机学院);University at Albany, State University of New York(纽约州立大学奥尔巴尼分校)
Automatic liver segmentation plays an important role in computer-aided diagnosis and treatment. Manual segmentation of organs is a difficult and tedious task and so prone to human errors. In this paper, we propose an adaptive 3D region growing with subject-specific conditions. For this aim we use the intensity distribution of most probable voxels in prior map along with location prior. We also incorporate the boundary of target organs to restrict the region growing. In order to obtain strong edges and high contrast, we propose an effective contrast enhancement algorithm to facilitate more accu…