arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 0712.3596cond-mat.softcond-mat.stat-mech
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与自身轨道相互作用的分子马达

Molecular Motors Interacting with Their Own Tracks

Max N. Artyomov, Alexander Yu. Morozov, Anatoly B. Kolomeisky

摘要:

通过分析可精确求解的离散态"烧桥“模型,从理论上研究了沿线性晶格运动并通过可逆破坏特定晶格键与之相互作用的分子马达的动力学.分子马达被视为扩散粒子,当经过它们时,可以不对称地破坏或重建周期性分布的弱连接。我们明确的动力学性质的计算表明,耦合的无偏分子马达与桥燃烧机制的运输导致一个定向运动,降低波动,并产生一个动态的过渡在低浓度的弱链接的限制。后向偏置分子马达与烧桥机制之间的相互作用产生了复杂的动力学行为。对于可逆解离,分子马达的向后运动减慢。在一定的参数范围内,分子马达的运动方向会发生变化。分子马达也经历非单调的波动,由于两个相反的机制的作用:减少活动后,烧毁的网站和锁定的大波动。当两种机制具有可比性时,会观察到较大的空间波动。对于桥的不可逆燃烧,分子马达的性质是不同的,在一定浓度范围内,速度和波动被抑制,并且还观察到动态转变。系统的动力学进行了讨论的有效驱动力和不同的扩散制度之间的过渡。

英文摘要:

Dynamics of molecular motors that move along linear lattices and interact with them via reversible destruction of specific lattice bonds is investigated theoretically by analyzing exactly solvable discrete-state ``burnt-bridge'' models. Molecular motors are viewed as diffusing particles that can asymmetrically break or rebuild periodically distributed weak links when passing over them. Our explicit calculations of dynamic properties show that coupling the transport of the unbiased molecular motor with the bridge-burning mechanism leads to a directed motion that lowers fluctuations and produces a dynamic transition in the limit of low concentration of weak links. Interaction between the backward biased molecular motor and the bridge-burning mechanism yields a complex dynamic behavior. For the reversible dissociation the backward motion of the molecular motor is slowed down. There is a change in the direction of the molecular motor's motion for some range of parameters. The molecular motor also experiences non-monotonic fluctuations due to the action of two opposing mechanisms: the reduced activity after the burned sites and locking of large fluctuations. Large spatial fluctuations are observed when two mechanisms are comparable. The properties of the molecular motor are different for the irreversible burning of bridges where the velocity and fluctuations are suppressed for some concentration range, and the dynamic transition is also observed. Dynamics of the system is discussed in terms of the effective driving forces and transitions between different diffusional regimes.

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