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arXiv physics/02071292002-07physics.med-phphysics.ins-det

In-Vivo NMR of Hyperpolarized Helium-3 in the Human Lung at Very Low Magnetic Fields

Christopher P. Bidinosti, Jamal Choukeife, Pierre-Jean Nacher, Geneviève Tastevin

备注：: In press: Journal of Magnetic Resonance. 22 pages, 8 figures, 30 references
DOI：: 10.1016/S1090-7807(02)00198-2

英文摘要：

We present NMR measurements of the diffusion of hyperpolarized helium-3 in the human lung performed at fields much lower than those of conventional MRI scanners. The measurements were made on standing subjects using homebuilt apparatus operating at 3 mT. Oxygen-limited transverse relaxation (T2 up to 15-35 s) could be measured in-vivo. Accurate global diffusion measurements have been performed in-vivo and in-vitro. 1D ADC mapping with high SNR demonstrates the real possibility of performing quality lung imaging at extremely low fields.

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