分子进化中的母体效应
Maternal effects in molecular evolution
摘要:
我们介绍了一个模型的分子进化中,一个人的健身既取决于自己和父母的基因型。该模型可以通过一个非线性映射到标准的准物种模型来解决。对亲本基因型的依赖性从平均适合度中取消,但不从个体序列浓度中取消。对于有限群体,误差阈值的位置对亲本基因型的影响非常敏感。除了生物学应用,我们的模型对于理解自我复制计算机程序的动力学也很重要。
英文摘要:
We introduce a model of molecular evolution in which the fitness of an individual depends both on its own and on the parent's genotype. The model can be solved by means of a nonlinear mapping onto the standard quasispecies model. The dependency on the parental genotypes cancels from the mean fitness, but not from the individual sequence concentrations. For finite populations, the position of the error threshold is very sensitive to the influence from parent genotypes. In addition to biological applications, our model is important for understanding the dynamics of self-replicating computer programs.
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