精确度、多样性和代价相互作用驱动的分子密码进化的简单模型
A simple model for the evolution of molecular codes driven by the interplay of accuracy, diversity and cost
摘要：
分子密码将一种分子中的信息翻译成另一种分子语言。我们介绍了一个简单的模型，将分子代码作为嘈杂的信息通道。最佳编码是一种准确有效地传递信息的通道，同时降低错误的影响。这三个相互冲突的需求的平衡，最小的错误负载，最小的资源成本和最大的词汇多样性，定义了代码的适应性。该模型提出了一种机制，当进化改变控制这种平衡的参数时，代码的出现，两种分子语言之间的映射变得非随机。这种机制是证明了一个简单的玩具模型，形式上相当于一个平均场伊辛磁铁。
英文摘要：
Molecular codes translate information written in one type of molecules into another molecular language. We introduce a simple model that treats molecular codes as noisy information channels. An optimal code is a channel that conveys information accurately and efficiently while keeping down the impact of errors. The equipoise of the three conflicting needs, for minimal error-load, minimal cost of resources and maximal diversity of vocabulary, defines the fitness of the code. The model suggests a mechanism for the emergence of a code when evolution varies the parameters that control this equipoise and the mapping between the two molecular languages becomes non-random. This mechanism is demonstrated by a simple toy model that is formally equivalent to a mean-field Ising magnet.
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