具有波动峰值的适应度景观上的拟种进化
Quasispecies evolution on a fitness landscape with a fluctuating peak
摘要:
研究了具有单峰波动高度的适应度景观上的拟物种演化问题。在回复突变可以忽略的近似下,速率方程可以解析求解。结果表明,这类动态景观的错误阈值定义的时间平均选择压力。在一个周期性波动的健身峰值的情况下,我们还研究了先前记录的低通滤波器效应的相移和响应幅度。一个小的谐波波动的特殊情况下,处理解析。
英文摘要:
A quasispecies evolving on a fitness landscape with a single peak of fluctuating height is studied. In the approximation that back mutations can be ignored, the rate equations can be solved analytically. It is shown that the error threshold on this class of dynamic landscapes is defined by the time average of the selection pressure. In the case of a periodically fluctuating fitness peak we also study the phase-shift and response amplitude of the previously documented low-pass filter effect. The special case of a small harmonic fluctuation is treated analytically.
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