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arXiv math/0602139math.APq-bio.CBq-bio.MNq-bio.PE
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细菌趋化性复双曲模型的整体存在性结果

Global existence results for complex hyperbolic models of bacterial chemotaxis

Radek Erban, Hyung Ju Hwang

摘要:

细菌能够通过改变它们的运动规则来响应环境信号。当我们考虑到环境中的化学信号时,这种行为通常被称为趋化性。在个体水平上,趋化性由几个步骤组成。首先,细胞利用其膜上的受体检测细胞外信号。然后,细胞通过细胞内信号转导网络处理信号信息,最后通过相应地改变其运动行为来响应。在种群水平上,趋化性可以导致细菌聚集、行波或模式形成,重要的任务是用基于个体的模型来解释种群水平上的行为。以前已经表明,传输方程框架是适合连接不同层次的细菌趋化性建模。在本文中,我们耦合的传输方程的细菌与(抛物/椭圆)方程的细胞外信号。我们证明了一般双曲型细胞趋化模型的整体解的存在性,该模型通过细胞内生化网络处理细胞外信号的信息,并通过改变细胞外信号进行相互作用。根据信号传导模型的性质,给出了该模型全局存在的条件。

英文摘要:

Bacteria are able to respond to environmental signals by changing their rules of movement. When we take into account chemical signals in the environment, this behaviour is often called chemotaxis. At the individual-level, chemotaxis consists of several steps. First, the cell detects the extracellular signal using receptors on its membrane. Then, the cell processes the signal information through the intracellular signal transduction network, and finally it responds by altering its motile behaviour accordingly. At the population level, chemotaxis can lead to aggregation of bacteria, travelling waves or pattern formation, and the important task is to explain the population-level behaviour in terms of individual-based models. It has been previously shown that the transport equation framework is suitable for connecting different levels of modelling of bacterial chemotaxis. In this paper, we couple the transport equation for bacteria with the (parabolic/elliptic) equation for the extracellular signals. We prove global existence of solutions for the general hyperbolic chemotaxis models of cells which process the information about the extracellular signal through the intracellular biochemical network and interact by altering the extracellular signal as well. The conditions for global existence in terms of the properties of the signal transduction model are given.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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