In this paper we propose a general methodology, based on multiple testing, for testing that the mean of a Gaussian vector in R^n belongs to a convex set. We show that the test achieves its nominal level, and characterize a class of vectors over which the tests achieve a prescribed power. In the functional regression model this general methodology is applied to test some qualitative hypotheses on the regression function. For example, we test that the regression function is positive, increasing, convex, or more generally, satisfies a differential inequality. Uniform separation rates over classes of smooth functions are established and a comparison with other results in the literature is provided. A simulation study evaluates some of the procedures for testing monotonicity.
Recently, several authors have re-examined the power of the classical F-test in linear regression in a `large-p, large-n' framework (cf. Zhong and Chen (2011), Wang and Cui (2013)). They highlight the loss of power as the number of regressors p increases relative to sample size n. These papers essentially focus only on the overall test of the null hypothesis that all p slope coefficients are equal to zero. Here, we consider the general case of testing q linear hypotheses on the (p+1)-dimensional regression parameter vector that includes p slope coefficients and an intercept parameter. In the c…
Consider a nonparametric regression model with one-sided errors and regression function in a general Hölder class. We estimate the regression function via minimization of the local integral of a polynomial approximation. We show uniform rates of convergence for the simple regression estimator as well as for a smooth version. These rates carry over to mean regression models with a symmetric and bounded error distribution. In such a setting, one obtains faster rates for irregular error distributions concentrating sufficient mass near the endpoints than for the usual regular distributions. The re…
Semiparametric models are often considered for analyzing longitudinal data for a good balance between flexibility and parsimony. In this paper, we study a class of marginal partially linear quantile models with possibly varying coefficients. The functional coefficients are estimated by basis function approximations. The estimation procedure is easy to implement, and it requires no specification of the error distributions. The asymptotic properties of the proposed estimators are established for the varying coefficients as well as for the constant coefficients. We develop rank score tests for hy…
We consider a regression model with errors that are a.s. negative. Thus the regression function is not the expected value of the observations but the right endpoint of their support. We develop two goodness-of-fit tests for the hypotheses that the regression function is an affine function, study the asymptotic distributions of the test statistics in order to approximately fix the sizes of the tests, derive their finite-sample properties based on simulations and apply them to life expectancy data.
Recently a distribution free approach for testing parametric hypotheses based on unitary transformations has been suggested in \cite{Khm13, Khm16, Khm17} and further studied in \cite{Ngu17} and \cite{Rob19}. In this note we show that the transformation takes extremely simple form in distribution free testing of linear regression. Then we extend it to general parametric regression with vector-valued covariates.
For a multivariate linear model, Wilk's likelihood ratio test (LRT) constitutes one of the cornerstone tools. However, the computation of its quantiles under the null or the alternative requires complex analytic approximations and more importantly, these distributional approximations are feasible only for moderate dimension of the dependent variable, say $p\le 20$. On the other hand, assuming that the data dimension $p$ as well as the number $q$ of regression variables are fixed while the sample size $n$ grows, several asymptotic approximations are proposed in the literature for Wilk's $\bLa$ …
This paper studies the high-dimensional mixed linear regression (MLR) where the output variable comes from one of the two linear regression models with an unknown mixing proportion and an unknown covariance structure of the random covariates. Building upon a high-dimensional EM algorithm, we propose an iterative procedure for estimating the two regression vectors and establish their rates of convergence. Based on the iterative estimators, we further construct debiased estimators and establish their asymptotic normality. For individual coordinates, confidence intervals centered at the debiased …
We consider the problem of inference on a regression function at a point when the entire function satisfies a sign or shape restriction under the null. We propose a test that achieves the optimal minimax rate adaptively over a range of Hölder classes, up to a $\log\log n$ term, which we show to be necessary for adaptation. We apply the results to adaptive one-sided tests for the regression discontinuity parameter under a monotonicity restriction, the value of a monotone regression function at the boundary and the proportion of true null hypotheses in a multiple testing problem.
This paper considers the quantile regression approach for partially linear spatial autoregressive models with possibly varying coefficients. B-spline is employed for the approximation of varying coefficients. The instrumental variable quantile regression approach is employed for parameter estimation. The rank score tests are developed for hypotheses on the coefficients, including the hypotheses on the non-varying coefficients and the constancy of the varying coefficients. The asymptotic properties of the proposed estimators and test statistics are both established. Monte Carlo simulations are …
We propose in this work to derive a CLT in the functional linear regression model to get confidence sets for prediction based on functional linear regression. The main difficulty is due to the fact that estimation of the functional parameter leads to a kind of ill-posed inverse problem. We consider estimators that belong to a large class of regularizing methods and we first show that, contrary to the multivariate case, it is not possible to state a CLT in the topology of the considered functional space. However, we show that we can get a CLT for the weak topology under mild hypotheses and in p…
We propose a method for constructing p-values for general hypotheses in a high-dimensional linear model. The hypotheses can be local for testing a single regression parameter or they may be more global involving several up to all parameters. Furthermore, when considering many hypotheses, we show how to adjust for multiple testing taking dependence among the p-values into account. Our technique is based on Ridge estimation with an additional correction term due to a substantial projection bias in high dimensions. We prove strong error control for our p-values and provide sufficient conditions f…
In transformation regression models the response is transformed before fitting a regression model to covariates and transformed response. We assume such a model where the errors are independent from the covariates and the regression function is modeled nonparametrically. We suggest a test for goodness-of-fit of a parametric transformation class based on a distance between a nonparametric transformation estimator and the parametric class. We present asymptotic theory under the null hypothesis of validity of the semi-parametric model and under local alternatives. A bootstrap algorithm is suggest…
We consider the problem of sparsity testing in the high-dimensional linear regression model. The problem is to test whether the number of non-zero components (aka the sparsity) of the regression parameter $θ^*$ is less than or equal to $k_0$. We pinpoint the minimax separation distances for this problem, which amounts to quantifying how far a $k_1$-sparse vector $θ^*$ has to be from the set of $k_0$-sparse vectors so that a test is able to reject the null hypothesis with high probability. Two scenarios are considered. In the independent scenario, the covariates are i.i.d. normally distributed …
Multiple testing literature contains ample research on controlling false discoveries for hypotheses classified according to one criterion, which we refer to as one-way classified hypotheses. Although simultaneous classification of hypotheses according to two different criteria, resulting in two-way classified hypotheses, do often occur in scientific studies, no such research has taken place yet, as far as we know, under this structure. This article produces procedures, both in their oracle and data-adaptive forms, for controlling the overall false discovery rate (FDR) across all hypotheses eff…
Model checking plays an important role in linear regression as model misspecification seriously affects the validity and efficiency of regression analysis. In practice, model checking is often performed by subjectively evaluating the plot of the model's residuals. This approach is objectified by constructing a random process from the model's residuals, however due to a very complex covariance function obtaining the exact distribution of the test statistic is intractable. Several solutions to overcome this have been proposed, however the simulation and bootstrap based approaches are only asympt…
A polynomial that is nonnegative over a given interval is called a positive polynomial. The set of such positive polynomials forms a closed convex cone $K$. In this paper, we consider the likelihood ratio test for the hypothesis of positivity that the estimand polynomial regression curve is a positive polynomial. By considering hierarchical hypotheses including the hypothesis of positivity, we define nested likelihood ratio tests, and derive their null distributions as mixtures of chi-square distributions by using the volume-of-tubes method. The mixing probabilities are obtained by utilizing t…
Analyzing polytomous response from a complex survey scheme, like stratified or cluster sampling is very crucial in several socio-economics applications. We present a class of minimum quasi weighted density power divergence estimators for the polytomous logistic regression model with such a complex survey. This family of semiparametric estimators is a robust generalization of the maximum quasi weighted likelihood estimator exploiting the advantages of the popular density power divergence measure. Accordingly robust estimators for the design effects are also derived. Robust testing of general li…
We consider the problem of estimating the regression function in functional linear regression models by proposing a new type of projection estimators which combine dimension reduction and thresholding. The introduction of a threshold rule allows to get consistency under broad assumptions as well as minimax rates of convergence under additional regularity hypotheses. We also consider the particular case of Sobolev spaces generated by the trigonometric basis which permits to get easily mean squared error of prediction as well as estimators of the derivatives of the regression function. We prove …
In a recent paper Birke and Bissantz (2008) considered the problem of nonparametric estimation in inverse regression models with convolution-type operators. For multivariate predictors nonparametric methods suffer from the curse of dimensionality and we consider inverse regression models with the additional qualitative assumption of additivity. In these models several additive estimators are studied. In particular, we investigate estimators under the random design assumption which are applicable when observations are not available on a grid. Finally, we compare this estimator with the marginal…
We develop inference procedures for longitudinal data where some of the measurements are censored by fixed constants. We consider a semi-parametric quantile regression model that makes no distributional assumptions. Our research is motivated by the lack of proper inference procedures for data from biomedical studies where measurements are censored due to a fixed quantification limit. In such studies the focus is often on testing hypotheses about treatment equality. To this end, we propose a rank score test for large sample inference on a subset of the covariates. We demonstrate the importance …
This paper deals with the Fisher-consistency, weak continuity and differentiability of estimating functionals corresponding to a class of both linear and nonlinear regression high breakdown M estimates, which includes S and MM estimates. A restricted type of differentiability, called weak differentiability, is defined, which suffices to prove the asymptotic normality of estimates based on the functionals. This approach allows to prove the consistency, asymptotic normality and qualitative robustness of M estimates under more general conditions than those required in standard approaches. In part…
Much of the research on multiple comparison and simultaneous inference in the past sixty years or so has been for the comparisons of several population means. Spurrier (1999) seems to be the first to study the multiple comparison of several simple linear regression lines by using simultaneous confidence bands. In this paper, the work of Liu et al. (2004) for finite comparisons of several univariate linear regression models by using simultaneous confidence bands has been extended to finite comparison of several multivariate linear regression models by using simultaneous confidence tubes. We sho…
In this article, we propose a generalized weighted version of the well-known Benjamini-Hochberg (BH) procedure. The rigorous weighting scheme used by our method enables it to encode structural information from simultaneous multi-way classification as well as hierarchical partitioning of hypotheses into groups, with provisions to accommodate overlapping groups. The method is proven to control the False Discovery Rate (FDR) when the p-values involved are Positively Regression Dependent on the Subset (PRDS) of null p-values. A data-adaptive version of the method is proposed. Simulations show that…
In this paper, we develop a systematic theory for high dimensional analysis of variance in multivariate linear regression, where the dimension and the number of coefficients can both grow with the sample size. We propose a new \emph{U}~type test statistic to test linear hypotheses and establish a high dimensional Gaussian approximation result under fairly mild moment assumptions. Our general framework and theory can be applied to deal with the classical one-way multivariate ANOVA and the nonparametric one-way MANOVA in high dimensions. To implement the test procedure in practice, we introduce …
Cluster-weighted modeling (CWM) is a mixture approach for modeling the joint probability of a response variable and a set of explanatory variables. The parameters are estimated by means of the expectation-maximization algorithm according to the maximum likelihood approach. Under Gaussian assumptions, we analyse the complete-data likelihood function of cluster weighted models. Further, under suitable hypotheses we show that the maximization of the likelihood function of Gaussian cluster weighted models leads to the same parameter estimates of finite mixtures of regression and finite mixtures of…
This paper derives a new family of estimators, namely the minimum density power divergence estimators, as a robust generalization of the maximum likelihood estimator for the polytomous logistic regression model. Based on these estimators, a family of Wald-type test statistics for linear hypotheses is introduced. Robustness properties of both the proposed estimators and the test statistics are theoretically studied through the classical influence function analysis. Appropriate real life examples are presented to justify the requirement of suitable robust statistical procedures in place of the l…
In this paper we discuss how to evaluate the differences between fitted logistic regression models across sub-populations. Our motivating example is in studying computerized diagnosis for learning disabilities, where sub-populations based on gender may or may not require separate models. In this context, significance tests for hypotheses of no difference between populations may provide perverse incentives, as larger variances and smaller samples increase the probability of not-rejecting the null. We argue that equivalence testing for a prespecified tolerance level on population differences inc…
Standard statistical methods that do not take proper account of the complexity of survey design can lead to erroneous inferences when applied to survey data due to unequal selection probabilities, clustering, and other design features. In particular, the actual type I error rates of tests of hypotheses using standard methods can be much bigger than the nominal significance level. Methods that take account of survey design features in testing hypotheses have been proposed, including Wald tests and quasi-score tests that involve the estimated covariance matrices of parameter estimates. In this p…
University of Southern California（南加州大学）；Princeton University（普林斯顿大学）
Hypothesis testing in the linear regression model is a fundamental statistical problem. We consider linear regression in the high-dimensional regime where the number of parameters exceeds the number of samples ($p> n$). In order to make informative inference, we assume that the model is approximately sparse, that is the effect of covariates on the response can be well approximated by conditioning on a relatively small number of covariates whose identities are unknown. We develop a framework for testing very general hypotheses regarding the model parameters. Our framework encompasses testing wh…
In this paper we propose a new test of heteroscedasticity for parametric regression models and partial linear regression models in high dimensional settings. When the dimension of covariates is large, existing tests of heteroscedasticity perform badly due to the \curse of dimensionality". To attack this problem, we construct a test of heteroscedasticity by using a projection-based empirical process. We study the asymptotic properties of the test statistic under the null hypothesis and alternative hypotheses. It is shown that the test can detect local alternatives departure from the null hypoth…
We propose a novel resampling-based method to construct an asymptotically exact test for any subset of hypotheses on coefficients in high-dimensional linear regression. It can be embedded into any multiple testing procedure to make confidence statements on relevant predictor variables. The method constructs permutation test statistics for any individual hypothesis by means of repeated splits of the data and a variable selection technique; then it defines a test for any subset by suitably aggregating its variables' test statistics. The resulting procedure is extremely flexible, as it allows dif…
Linear regression is a classical paradigm in statistics. A new look at it is provided via the lens of universal learning. In applying universal learning to linear regression the hypotheses class represents the label $y\in {\cal R}$ as a linear combination of the feature vector $x^Tθ$ where $x\in {\cal R}^M$, within a Gaussian error. The Predictive Normalized Maximum Likelihood (pNML) solution for universal learning of individual data can be expressed analytically in this case, as well as its associated learnability measure. Interestingly, the situation where the number of parameters $M$ may ev…
University of Wisconsin-Madison（威斯康星大学麦迪逊分校）；University of California, San Diego（加州大学圣地亚哥分校）；Web 3 Foundation（Web3基金会）
We study the problem of list-decodable linear regression, where an adversary can corrupt a majority of the examples. Specifically, we are given a set $T$ of labeled examples $(x, y) \in \mathbb{R}^d \times \mathbb{R}$ and a parameter $0< α<1/2$ such that an $α$-fraction of the points in $T$ are i.i.d. samples from a linear regression model with Gaussian covariates, and the remaining $(1-α)$-fraction of the points are drawn from an arbitrary noise distribution. The goal is to output a small list of hypothesis vectors such that at least one of them is close to the target regression vector. Our m…
Self and Mauritsen (1988) developed a sample size determination procedure for score tests in generalized linear models under contiguous alternatives. Its performance may deteriorate when the effect size is large. We propose a modification of the Self-Mauritsen method by taking into account of the variance of the score statistic under both the null and alternative hypotheses, and extend the method to noninferiority trials. The modified approach is employed to calculate the sample size for the logistic regression and negative binomial regression in superiority and noninferiority trials. We furth…
Multiple testing problems arising in modern scientific applications can involve simultaneously testing thousands or even millions of hypotheses, with relatively few true signals. In this paper, we consider the multiple testing problem where prior information is available (for instance, from an earlier study under different experimental conditions), that can allow us to test the hypotheses as a ranked list in order to increase the number of discoveries. Given an ordered list of n hypotheses, the aim is to select a data-dependent cutoff k and declare the first k hypotheses to be statistically si…
Hierarchical inference in (generalized) regression problems is powerful for finding significant groups or even single covariates, especially in high-dimensional settings where identifiability of the entire regression parameter vector may be ill-posed. The general method proceeds in a fully data-driven and adaptive way from large to small groups or singletons of covariates, depending on the signal strength and the correlation structure of the design matrix. We propose a novel hierarchical multiple testing adjustment that can be used in combination with any significance test for a group of covar…
The random coefficients model is an extension of the linear regression model that allows for unobserved heterogeneity in the population by modeling the regression coefficients as random variables. Given data from this model, the statistical challenge is to recover information about the joint density of the random coefficients which is a multivariate and ill-posed problem. Because of the curse of dimensionality and the ill-posedness, pointwise nonparametric estimation of the joint density is difficult and suffers from slow convergence rates. Larger features, such as an increase of the density a…
The behavior of the power function of autocorrelation tests such as the Durbin-Watson test in time series regressions or the Cliff-Ord test in spatial regression models has been intensively studied in the literature. When the correlation becomes strong, Krämer (1985) (for the Durbin-Watson test) and Krämer (2005) (for the Cliff-Ord test) have shown that the power can be very low, in fact can converge to zero, under certain circumstances. Motivated by these results, Martellosio (2010) set out to build a general theory that would explain these findings. Unfortunately, Martellosio (2010) does not…
