Fine-Tuning Cycle-GAN for Domain Adaptation of MRI Images
Department of Diagnostics and Intervention, and Biomedical Engineering, Umea University（乌梅大学诊断与介入系及生物医学工程系）；Department of Computer Science and Information Engineering, National Taipei University of Technology（国立台北科技大学计算机科学与信息工程系）；IRC for Bio Systems and Machines, King Fahd University of Petroleum and Minerals（国王法赫德石油与矿物大学生物系统与机器研究院）
Mohd Usama, Belal Ahmad, Faleh Menawer R Althiyabi
Magnetic Resonance Imaging (MRI) scans acquired from different scanners or institutions often suffer from domain shifts owing to variations in hardware, protocols, and acquisition parameters. This discrepancy degrades the performance of deep learning models trained on source domain data when applied to target domain images. In this study, we propose a Cycle-GAN-based model for unsupervised medical-image domain adaptation. Leveraging CycleGANs, our model learns bidirectional mappings between the source and target domains without paired training data, preserving the anatomical content of the images. By leveraging Cycle-GAN capabilities with content and disparity loss for adaptation tasks, we ensured image-domain adaptation while maintaining image integrity. Several experiments on MRI datasets demonstrated the efficacy of our model in bidirectional domain adaptation without labelled data. Furthermore, research offers promising avenues for improving the diagnostic accuracy of healthcare. The statistical results confirm that our approach improves model performance and reduces domain-related variability, thus contributing to more precise and consistent medical image analysis.
Deep learning-based semantic segmentation methods have an intrinsic limitation that training a model requires a large amount of data with pixel-level annotations. To address this challenging issue, many researchers give attention to unsupervised domain adaptation for semantic segmentation. Unsupervised domain adaptation seeks to adapt the model trained on the source domain to the target domain. In this paper, we introduce a self-ensembling technique, one of the successful methods for domain adaptation in classification. However, applying self-ensembling to semantic segmentation is very difficu…
Biomedical Image Analysis Group, Imperial College London（帝国理工学院生物医学图像分析组）；Comprehensive Cancer Imaging Centre, Hammersmith Hospital, Imperial College London（帝国理工学院哈默史密斯医院综合癌症成像中心）；The Royal Marsden NHS Foundation Trust, London（伦敦皇家马斯登国民保健服务基金会信托）
The variations in multi-center data in medical imaging studies have brought the necessity of domain adaptation. Despite the advancement of machine learning in automatic segmentation, performance often degrades when algorithms are applied on new data acquired from different scanners or sequences than the training data. Manual annotation is costly and time consuming if it has to be carried out for every new target domain. In this work, we investigate automatic selection of suitable subjects to be annotated for supervised domain adaptation using the concept of reverse classification accuracy (RCA…
University of Basel（巴塞尔大学）；Massachusetts General Hospital（麻省总医院）；Harvard Medical School（哈佛医学院）；Gillberg Neuropsychiatry Center（吉尔伯格神经精神病学中心）；Sahlgrenska Academy（萨尔格伦斯卡学院）；University of Gothenburg（哥德堡大学）；University Hospital Basel（巴塞尔大学医院）
The limited availability of large image datasets, mainly due to data privacy and differences in acquisition protocols or hardware, is a significant issue in the development of accurate and generalizable machine learning methods in medicine. This is especially the case for Magnetic Resonance (MR) images, where different MR scanners introduce a bias that limits the performance of a machine learning model. We present a novel method that learns to ignore the scanner-related features present in MR images, by introducing specific additional constraints on the latent space. We focus on a real-world c…
Radboud University Medical Center（拉德堡德大学医学中心）；Radboud University（拉德堡德大学）；University of British Columbia（不列颠哥伦比亚大学）
Magnetic Resonance Imaging (MRI) is widely used in routine clinical diagnosis and treatment. However, variations in MRI acquisition protocols result in different appearances of normal and diseased tissue in the images. Convolutional neural networks (CNNs), which have shown to be successful in many medical image analysis tasks, are typically sensitive to the variations in imaging protocols. Therefore, in many cases, networks trained on data acquired with one MRI protocol, do not perform satisfactorily on data acquired with different protocols. This limits the use of models trained with large an…
The primary goal of this work is to study the effectiveness of an unsupervised domain adaptation approach for various applications such as binary classification and anomaly detection in the context of Alzheimer's disease (AD) detection for the OASIS datasets. We also explore image reconstruction and image synthesis for analyzing and generating 3D structural MRI data to establish performance benchmarks for anomaly detection. We successfully demonstrate that domain adaptation improves the performance of AD detection when implemented in both supervised and unsupervised settings. Additionally, the…
Istituto Italiano di Tecnologia（意大利理工学院）；Stanford University（斯坦福大学）；Università di Verona（维罗纳大学）
Recent works showed that Generative Adversarial Networks (GANs) can be successfully applied in unsupervised domain adaptation, where, given a labeled source dataset and an unlabeled target dataset, the goal is to train powerful classifiers for the target samples. In particular, it was shown that a GAN objective function can be used to learn target features indistinguishable from the source ones. In this work, we extend this framework by (i) forcing the learned feature extractor to be domain-invariant, and (ii) training it through data augmentation in the feature space, namely performing featur…
Learning from Heterogeneous Structural MRI via Collaborative Domain Adaptation for Late-Life Depression Assessment
Department of Radiology and Biomedical Research Imaging Center (BRIC), University of North Carolina at Chapel Hill（放射科与生物医学研究成像中心（BRIC），北卡罗来纳大学教堂山分校）；School of Computer Science and Engineering, Shandong University of Science and Technology（计算机科学与工程学院，山东科技大学）
National Chiao Tung University（国立交通大学）；National Yang-Ming University（国立阳明大学）；National Yang Ming Chiao Tung University（国立阳明交通大学）
We propose a Paired Few-shot GAN (PFS-GAN) model for learning generators with sufficient source data and a few target data. While generative model learning typically needs large-scale training data, our PFS-GAN not only uses the concept of few-shot learning but also domain shift to transfer the knowledge across domains, which alleviates the issue of obtaining low-quality generator when only trained with target domain data. The cross-domain datasets are assumed to have two properties: (1) each target-domain sample has its source-domain correspondence and (2) two domains share similar content in…
University of Central Florida（中佛罗里达大学）；National Cancer Institute, National Institutes of Health（美国国立卫生研究院国家癌症研究所）；Frederick National Laboratory for Cancer Research（弗雷德里克国家癌症研究实验室）
Abdominal fat quantification is critical since multiple vital organs are located within this region. Although computed tomography (CT) is a highly sensitive modality to segment body fat, it involves ionizing radiations which makes magnetic resonance imaging (MRI) a preferable alternative for this purpose. Additionally, the superior soft tissue contrast in MRI could lead to more accurate results. Yet, it is highly labor intensive to segment fat in MRI scans. In this study, we propose an algorithm based on deep learning technique(s) to automatically quantify fat tissue from MR images through a c…
School of Information Science and Technology, ShanghaiTech University（上海科技大学信息科学与技术学院）；College of Computer Science, Sichuan University（四川大学计算机学院）；Shanghai Engineering Research Center of Intelligent Vision and Imaging（上海智能视觉与成像工程技术研究中心）；Institute of High Performance Computing (IHPC), Agency for Science, Technology and Research (A*STAR)（新加坡科技研究局高性能计算研究所）
Robert Bosch Corporate Research（博世企业研究院）；KLA（科磊）；Birla Institute of Technology and Science, Pilani（皮拉尼比特拉技术与科学学院）
While developing perception based deep learning models, the benefit of synthetic data is enormous. However, performance of networks trained with synthetic data for certain computer vision tasks degrade significantly when tested on real world data due to the domain gap between them. One of the popular solutions in bridging this gap between synthetic and actual world data is to frame it as a domain adaptation task. In this paper, we propose and evaluate novel ways for the betterment of such approaches. In particular we build upon the method of UNIT-GAN. In normal GAN training for the task of dom…
University of Otago（奥塔哥大学）；Institute of Information Engineering Chinese Academy of Sciences（中国科学院信息工程研究所）
Current deep domain adaptation methods used in computer vision have mainly focused on learning discriminative and domain-invariant features across different domains. In this paper, we present a novel approach that bridges the domain gap by projecting the source and target domains into a common association space through an unsupervised ``cross-grafted representation stacking'' (CGRS) mechanism. Specifically, we construct variational auto-encoders (VAE) for the two domains, and form bidirectional associations by cross-grafting the VAEs' decoder stacks. Furthermore, generative adversarial network…
UCL（伦敦大学学院）；UCLH NHS Foundation Trust（伦敦大学学院医院国民保健服务基金会信托）
Any novel medical imaging modality that differs from previous protocols e.g. in the number of imaging channels, introduces a new domain that is heterogeneous from previous ones. This common medical imaging scenario is rarely considered in the domain adaptation literature, which handles shifts across domains of the same dimensionality. In our work we rely on stochastic generative modeling to translate across two heterogeneous domains at pixel space and introduce two new loss functions that promote semantic consistency. Firstly, we introduce a semantic cycle-consistency loss in the source domain…
UCL（伦敦大学学院）；UCLH NHS Foundation Trust（伦敦大学学院医院NHS基金会信托）
The need for training data can impede the adoption of novel imaging modalities for learning-based medical image analysis. Domain adaptation methods partially mitigate this problem by translating training data from a related source domain to a novel target domain, but typically assume that a one-to-one translation is possible. Our work addresses the challenge of adapting to a more informative target domain where multiple target samples can emerge from a single source sample. In particular we consider translating from mp-MRI to VERDICT, a richer MRI modality involving an optimized acquisition pr…
King’s College London（伦敦国王学院）；Biomediq A/S（Biomediq公司）；University College London（伦敦大学学院）；Chelsea and Westminster Hospital NHS Foundation Trust（切尔西和威斯敏斯特医院NHS基金会信托）；Cereriu A/S（Cereriu公司）
Supervised learning algorithms trained on medical images will often fail to generalize across changes in acquisition parameters. Recent work in domain adaptation addresses this challenge and successfully leverages labeled data in a source domain to perform well on an unlabeled target domain. Inspired by recent work in semi-supervised learning we introduce a novel method to adapt from one source domain to $n$ target domains (as long as there is paired data covering all domains). Our multi-domain adaptation method utilises a consistency loss combined with adversarial learning. We provide results…
University of Maryland（马里兰大学）；Johns Hopkins University（约翰斯·霍普金斯大学）
Optimal Transport (OT) distances such as Wasserstein have been used in several areas such as GANs and domain adaptation. OT, however, is very sensitive to outliers (samples with large noise) in the data since in its objective function, every sample, including outliers, is weighed similarly due to the marginal constraints. To remedy this issue, robust formulations of OT with unbalanced marginal constraints have previously been proposed. However, employing these methods in deep learning problems such as GANs and domain adaptation is challenging due to the instability of their dual optimization s…
Magnetic resonance images (MRIs) are widely used to quantify vestibular schwannoma and the cochlea. Recently, deep learning methods have shown state-of-the-art performance for segmenting these structures. However, training segmentation models may require manual labels in target domain, which is expensive and time-consuming. To overcome this problem, domain adaptation is an effective way to leverage information from source domain to obtain accurate segmentations without requiring manual labels in target domain. In this paper, we propose an unsupervised learning framework to segment the VS and c…
Unsupervised Adversarial Domain Adaptation for Uterine layer Segmentation: From Labeled Cine to Unlabeled Dynamic EPI MRI
Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg（埃尔朗根-纽伦堡大学弗里德里希-亚历山大分校埃尔朗根大学医院放射学研究所）；CAIMED（CAIMED机构）；L3S（L3S机构）；Institut für Informationsverarbeitung, Leibniz University Hannover（汉诺威莱布尼茨大学信息处理研究所）
Université de Bretagne Sud（南布列塔尼大学）；IRISA（法国信息与随机系统研究所）；CNES（法国国家空间研究中心）；Thales Alenia Space（泰雷兹阿莱尼亚宇航公司）
In the field of remote sensing and more specifically in Earth Observation, new data are available every day, coming from different sensors. Leveraging on those data in classification tasks comes at the price of intense labelling tasks that are not realistic in operational settings. While domain adaptation could be useful to counterbalance this problem, most of the usual methods assume that the data to adapt are comparable (they belong to the same metric space), which is not the case when multiple sensors are at stake. Heterogeneous domain adaptation methods are a particular solution to this pr…
Friedrich-Alexander-Universität Erlangen-Nürnberg（埃尔朗根-纽伦堡弗里德里希-亚历山大大学）；University of Leeds（利兹大学）
Left ventricle segmentation and morphological assessment are essential for improving diagnosis and our understanding of cardiomyopathy, which in turn is imperative for reducing risk of myocardial infarctions in patients. Convolutional neural network (CNN) based methods for cardiac magnetic resonance (CMR) image segmentation rely on supervision with pixel-level annotations, and may not generalize well to images from a different domain. These methods are typically sensitive to variations in imaging protocols and data acquisition. Since annotating multi-sequence CMR images is tedious and subject …
Liver segmentation on images acquired using computed tomography (CT) and magnetic resonance imaging (MRI) plays an important role in clinical management of liver diseases. Compared to MRI, CT images of liver are more abundant and readily available. However, MRI can provide richer quantitative information of the liver compared to CT. Thus, it is desirable to achieve unsupervised domain adaptation for transferring the learned knowledge from the source domain containing labeled CT images to the target domain containing unlabeled MR images. In this work, we report a novel unsupervised domain adapt…
SHAPE: Structure-aware Hierarchical Unsupervised Domain Adaptation with Plausibility Evaluation for Medical Image Segmentation
School of Software, Northwestern Polytechnical University（西北工业大学软件学院）；School of Computer Science and Technology, Harbin Institute of Technology（哈尔滨工业大学计算机科学与技术学院）；School of Software Engineering, USTC（USTC软件工程学院）；Australian Institute of Health Innovation, Macquarie University（麦考瑞大学健康创新研究所）；Faculty of Applied Science, Macao Polytechnic University（澳门理工学院应用科学学院）；School of Computer Software, Tianjin University（天津大学计算机软件学院）
Indian Institute of Technology Bombay（印度理工学院孟买分校）；Goethe University Frankfurt（法兰克福歌德大学）
We tackle the novel problem of incremental unsupervised domain adaptation (IDA) in this paper. We assume that a labeled source domain and different unlabeled target domains are incrementally observed with the constraint that data corresponding to the current domain is only available at a time. The goal is to preserve the accuracies for all the past domains while generalizing well for the current domain. The IDA setup suffers due to the abrupt differences among the domains and the unavailability of past data including the source domain. Inspired by the notion of generative feature replay, we pr…
Domain Adaptation using Silver Standard Masks for Lateral Ventricle Segmentation in FLAIR MRI
Toronto Metropolitan University（多伦多都会大学）；University of Toronto（多伦多大学）；St. Michael’s Hospital（圣迈克尔医院）；Institute of Biomedical Engineering, Science and Technology (iBEST)（生物医学工程科学与技术研究所（iBEST））
Source-Free Collaborative Domain Adaptation via Multi-Perspective Feature Enrichment for Functional MRI Analysis
University of North Carolina at Chapel Hill（北卡罗来纳大学教堂山分校）；The Affiliated Hospital of TCM of Guangzhou Medical University（广州医科大学附属中医医院）；The First Affiliated Hospital of Guangzhou University of Chinese Medicine（广州中医药大学第一附属医院）；East China University of Science and Technology（华东理工大学）
Building robust deep learning-based models requires diverse training data, ideally from several sources. However, these datasets cannot be combined easily because of patient privacy concerns or regulatory hurdles, especially if medical data is involved. Federated learning (FL) is a way to train machine learning models without the need for centralized datasets. Each FL client trains on their local data while only sharing model parameters with a global server that aggregates the parameters from all clients. At the same time, each client's data can exhibit differences and inconsistencies due to t…
Mitigating 3D Prostate Biparametric MRI Data Scarcity through Domain Adaptation using Locally-Trained Latent Diffusion Models for Prostate Cancer Detection
Institute of Biomedical Engineering, University of Toronto（多伦多大学生物医学工程研究所）；Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital（圣心医院卢内尔-塔内本研究所）；KITE Research Institute, Toronto Rehabilitation Institute, University Health Network（多伦多康复研究所、KITE研究所在大学健康网络）；Joint Department of Medical Imaging, University of Toronto, Princess Margaret Hospital, and Sinai Health systems（多伦多大学联合医学影像部门、玛格丽特医院及辛纳医疗系统）；Department of Computer Science, University of Toronto（多伦多大学计算机科学系）；Faculty Affiliate of the Vector Institute, Toronto（向量研究所教职员工）
Generative Adversarial Neural Networks (GANs) are applied to the synthetic generation of prostate lesion MRI images. GANs have been applied to a variety of natural images, is shown show that the same techniques can be used in the medical domain to create realistic looking synthetic lesion images. 16mm x 16mm patches are extracted from 330 MRI scans from the SPIE ProstateX Challenge 2016 and used to train a Deep Convolutional Generative Adversarial Neural Network (DCGAN) utilizing cutting edge techniques. Synthetic outputs are compared to real images and the implicit latent representations indu…
DeepFakes are synthetic videos generated by swapping a face of an original image with the face of somebody else. In this paper, we describe our work to develop general, deep learning-based models to classify DeepFake content. We propose a novel framework for using Generative Adversarial Network (GAN)-based models, we call MRI-GAN, that utilizes perceptual differences in images to detect synthesized videos. We test our MRI-GAN approach and a plain-frames-based model using the DeepFake Detection Challenge Dataset. Our plain frames-based-model achieves 91% test accuracy and a model which uses our…
Imperial College London（帝国理工学院）；Royal Brompton Hospital（皇家布朗普顿医院）
Magnetic resonance imaging (MRI) is a widely used non-radiative and non-invasive method for clinical interrogation of organ structures and metabolism, with an inherently long scanning time. Methods by k-space undersampling and deep learning based reconstruction have been popularised to accelerate the scanning process. This work focuses on investigating how powerful transformers are for fast MRI by exploiting and comparing different novel network architectures. In particular, a generative adversarial network (GAN) based Swin transformer (ST-GAN) was introduced for the fast MRI reconstruction. T…
Cross-modality image estimation involves the generation of images of one medical imaging modality from that of another modality. Convolutional neural networks (CNNs) have been shown to be useful in identifying, characterising and extracting image patterns. Generative adversarial networks (GANs) use CNNs as generators and estimated images are discriminated as true or false based on an additional network. CNNs and GANs within the image estimation framework may be considered more generally as deep learning approaches, since imaging data tends to be large, leading to a larger number of network wei…
Imperial College London（伦敦帝国理工学院）；Royal Brompton Hospital（皇家布朗普顿医院）；Yantai University（烟台大学）；University of Cambridge（剑桥大学）；Beijing Institute of Technology（北京理工大学）
Magnetic Resonance Imaging (MRI) is a vital component of medical imaging. When compared to other image modalities, it has advantages such as the absence of radiation, superior soft tissue contrast, and complementary multiple sequence information. However, one drawback of MRI is its comparatively slow scanning and reconstruction compared to other image modalities, limiting its usage in some clinical applications when imaging time is critical. Traditional compressive sensing based MRI (CS-MRI) reconstruction can speed up MRI acquisition, but suffers from a long iterative process and noise-induce…
University of California, Los Angeles（加利福尼亚大学洛杉矶分校）；Cedars-Sinai Medical Center（西达赛奈医疗中心）
High-resolution (HR) magnetic resonance imaging (MRI) provides detailed anatomical information that is critical for diagnosis in the clinical application. However, HR MRI typically comes at the cost of long scan time, small spatial coverage, and low signal-to-noise ratio (SNR). Recent studies showed that with a deep convolutional neural network (CNN), HR generic images could be recovered from low-resolution (LR) inputs via single image super-resolution (SISR) approaches. Additionally, previous works have shown that a deep 3D CNN can generate high-quality SR MRIs by using learned image priors. …
Center for Magnetic Resonance Research (CMRR)（磁共振研究中心）；University of Minnesota Twin Cities（明尼苏达大学双城分校）
k-space undersampling is a standard technique to accelerate MR image acquisitions. Reconstruction techniques including GeneRalized Autocalibrating Partial Parallel Acquisition(GRAPPA) and its variants are utilized extensively in clinical and research settings. A reconstruction model combining GRAPPA with a conditional generative adversarial network (GAN) was developed and tested on multi-coil human brain images from the fastMRI dataset. For various acceleration rates, GAN and GRAPPA reconstructions were compared in terms of peak signal-to-noise ratio (PSNR) and structural similarity (SSIM). Fo…
NVIDIA Corporation（英伟达公司）；Seoul National University（首尔大学）
Positron Emission Tomography (PET) is now regarded as the gold standard for the diagnosis of Alzheimer's Disease (AD). However, PET imaging can be prohibitive in terms of cost and planning, and is also among the imaging techniques with the highest dosage of radiation. Magnetic Resonance Imaging (MRI), in contrast, is more widely available and provides more flexibility when setting the desired image resolution. Unfortunately, the diagnosis of AD using MRI is difficult due to the very subtle physiological differences between healthy and AD subjects visible on MRI. As a result, many attempts have…
Few-shot domain adaptation to multiple domains aims to learn a complex image distribution across multiple domains from a few training images. A naïve solution here is to train a separate model for each domain using few-shot domain adaptation methods. Unfortunately, this approach mandates linearly-scaled computational resources both in memory and computation time and, more importantly, such separate models cannot exploit the shared knowledge between target domains. In this paper, we propose DynaGAN, a novel few-shot domain-adaptation method for multiple target domains. DynaGAN has an adaptation…
Smoothness Similarity Regularization for Few-Shot GAN Adaptation
Bosch Center for Artificial Intelligence（博世人工智能中心）；University of Bonn（波恩大学）；Lamarr Institute for Machine Learning and Artificial Intelligence（拉马尔机器学习与人工智能研究所）
Université de Bourgogne Franche-Comté（勃艮第-弗朗什-孔泰大学）；Cardiac Simulation & Imaging Software（心脏模拟与成像软件公司）；University of Sherbrooke（舍布鲁克大学）；University Hospital of Dijon（第戎大学医院）
In this work, we propose a Variational Autoencoder (VAE) - Generative Adversarial Networks (GAN) model that can produce highly realistic MRI together with its pixel accurate groundtruth for the application of cine-MR image cardiac segmentation. On one side of our model is a Variational Autoencoder (VAE) trained to learn the latent representations of cardiac shapes. On the other side is a GAN that uses "SPatially-Adaptive (DE)Normalization" (SPADE) modules to generate realistic MR images tailored to a given anatomical map. At test time, the sampling of the VAE latent space allows to generate an…
Indian Institute of Technology Madras (IITM)（印度理工学院马德拉斯分校）；Healthcare Technology Innovation Centre (HTIC)（医疗技术创新中心）
Magnetic resonance imaging (MRI) is one of the best medical imaging modalities as it offers excellent spatial resolution and soft-tissue contrast. But, the usage of MRI is limited by its slow acquisition time, which makes it expensive and causes patient discomfort. In order to accelerate the acquisition, multiple deep learning networks have been proposed. Recently, Generative Adversarial Networks (GANs) have shown promising results in MRI reconstruction. The drawback with the proposed GAN based methods is it does not incorporate the prior information about the end goal which could help in bett…
Centro Algoritmi, University of Minho（米尼奥大学算法中心）；Université Paris-Saclay, CEA, CNRS, BAOBAB, NeuroSpin（巴黎萨克雷大学、法国原子能与可替代能源委员会、法国国家科学研究中心、BAOBAB、NeuroSpin）
Translational brain research using Magnetic Resonance Imaging (MRI) is becoming increasingly popular as animal models are an essential part of scientific studies and more ultra-high-field scanners are becoming available. Some disadvantages of MRI are the availability of MRI scanners and the time required for a full scanning session (it usually takes over 30 minutes). Privacy laws and the 3Rs ethics rule also make it difficult to create large datasets for training deep learning models. Generative Adversarial Networks (GANs) can perform data augmentation with higher quality than other techniques…
Wayne State University（韦恩州立大学）；University of Michigan（密歇根大学）；University of Wisconsin Madison（威斯康星大学麦迪逊分校）
In medical image synthesis, model training could be challenging due to the inconsistencies between images of different modalities even with the same patient, typically caused by internal status/tissue changes as different modalities are usually obtained at a different time. This paper proposes a novel deep learning method, Structure-aware Generative Adversarial Network (SA-GAN), that preserves the shapes and locations of in-consistent structures when generating medical images. SA-GAN is employed to generate synthetic computed tomography (synCT) images from magnetic resonance imaging (MRI) with…
ITU Vision Lab（伊斯坦布尔理工大学视觉实验室）；Istanbul Technical University（伊斯坦布尔理工大学）
Magnetic Resonance Angiography (MRA) has become an essential MR contrast for imaging and evaluation of vascular anatomy and related diseases. MRA acquisitions are typically ordered for vascular interventions, whereas in typical scenarios, MRA sequences can be absent in the patient scans. This motivates the need for a technique that generates inexistent MRA from existing MR multi-contrast, which could be a valuable tool in retrospective subject evaluations and imaging studies. In this paper, we present a generative adversarial network (GAN) based technique to generate MRA from T1-weighted and T…
Korea Advanced Institute of Science and Technology（韩国科学技术院）
As deep learning is showing unprecedented success in medical image analysis tasks, the lack of sufficient medical data is emerging as a critical problem. While recent attempts to solve the limited data problem using Generative Adversarial Networks (GAN) have been successful in generating realistic images with diversity, most of them are based on image-to-image translation and thus require extensive datasets from different domains. Here, we propose a novel model that can successfully generate 3D brain MRI data from random vectors by learning the data distribution. Our 3D GAN model solves both i…
Brain age estimation based on magnetic resonance imaging (MRI) is an active research area in early diagnosis of some neurodegenerative diseases (e.g. Alzheimer, Parkinson, Huntington, etc.) for elderly people or brain underdevelopment for the young group. Deep learning methods have achieved the state-of-the-art performance in many medical image analysis tasks, including brain age estimation. However, the performance and generalisability of the deep learning model are highly dependent on the quantity and quality of the training data set. Both collecting and annotating brain MRI data are extreme…
