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arXiv 2511.16498cs.CV

基于动态对比增强MRI的肿瘤分割:考虑成像时间

Acquisition Time-Informed Breast Tumor Segmentation from Dynamic Contrast-Enhanced MRI

Yale University(耶鲁大学)

Rui Wang, Yuexi Du, John Lewin, R. Todd Constable, Nicha C. Dvornek

AI总结:

本文提出了一种利用成像时间信息提升乳腺DCE-MRI肿瘤分割性能的方法,通过FiLM层调节模型特征,提高分割精度和泛化能力。

摘要:

动态对比增强磁共振成像(DCE-MRI)在乳腺癌筛查、肿瘤评估和治疗计划及监测中起着重要作用。不同组织中的对比度动态变化有助于在对比后图像中突出肿瘤。然而,变化的采集协议和个体因素导致组织外观的大幅变化,即使是在同一相(例如第一对比后相)中采集的图像,也使得自动肿瘤分割具有挑战性。在此,我们提出了一种肿瘤分割方法,该方法利用对图像采集时间的知识来调节模型特征,以适应特定的采集序列。我们通过特征级线性调节(FiLM)层整合采集时间,这是一种轻量级的方法,可用于整合时间信息,并能够利用每个成像研究中获取的完整、可变数量的图像。我们在大型公共多中心乳腺DCE-MRI数据集上,针对不同的基线和配置,使用不同骨干架构训练时间调节模型。在域内图像和公共域外数据集上的评估显示,整合相采集时间的知识提高了肿瘤分割性能和模型泛化能力。

英文摘要:

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) plays an important role in breast cancer screening, tumor assessment, and treatment planning and monitoring. The dynamic changes in contrast in different tissues help to highlight the tumor in post-contrast images. However, varying acquisition protocols and individual factors result in large variation in the appearance of tissues, even for images acquired in the same phase (e.g., first post-contrast phase), making automated tumor segmentation challenging. Here, we propose a tumor segmentation method that leverages knowledge of the image acquisition time to modulate model features according to the specific acquisition sequence. We incorporate the acquisition times using feature-wise linear modulation (FiLM) layers, a lightweight method for incorporating temporal information that also allows for capitalizing on the full, variables number of images acquired per imaging study. We trained baseline and different configurations for the time-modulated models with varying backbone architectures on a large public multisite breast DCE-MRI dataset. Evaluation on in-domain images and a public out-of-domain dataset showed that incorporating knowledge of phase acquisition time improved tumor segmentation performance and model generalization.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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