Accurate segmentation of the left atrium (LA) from cardiac MRI is critical for guiding atrial fibrillation (AF) ablation and constructing biophysical cardiac models. Manual delineation is time-consuming, observer-dependent, and impractical for large-scale or time-sensitive clinical workflows. Deep learning methods, particularly convolutional architectures, have recently demonstrated superior performance in medical image segmentation tasks. In this study, we applied the nnU-Net framework, an automated, self-configuring deep learning segmentation architecture, to the Left Atrial Segmentation Challenge 2013 dataset. The dataset consists of thirty MRI scans with corresponding expert-annotated masks. The nnU-Net model automatically adapted its preprocessing, network configuration, and training pipeline to the characteristics of the MRI data. Model performance was quantitatively evaluated using the Dice similarity coefficient (DSC), and qualitative results were compared against expert segmentations. The proposed nnUNet model achieved a mean Dice score of 93.5, demonstrating high overlap with expert annotations and outperforming several traditional segmentation approaches reported in previous studies. The network exhibited robust generalization across variations in left atrial shape, contrast, and image quality, accurately delineating both the atrial body and proximal pulmonary veins.
Two-Stage Deep Learning Framework for Quality Assessment of Left Atrial Late Gadolinium Enhanced MRI Images
Kahlert School of Computing, University of Utah(犹他大学卡勒特计算学院);Department of Biomedical Engineering, University of Utah(犹他大学生物医学工程系);Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah(犹他大学诺拉·埃克尔斯·哈里森心血管研究与培训研究所);Department of Biomedical Engineering, Johns Hopkins(约翰斯·霍普金斯大学生物医学工程系);Division of Cardiology, University of Utah(犹他大学心脏病学系);Department of Radiology and Imaging Sciences, University of Utah(犹他大学放射学与影像科学系);Scientific Computing and Imaging Institute, University of Utah(犹他大学科学计算与成像研究所)
Integrating Deep Learning in Cardiology: A Comprehensive Review of Atrial Fibrillation, Left Atrial Scar Segmentation, and the Frontiers of State-of-the-Art Techniques
University of Auckland(奥克兰大学);Auckland Bioengineering Institute(奥克兰生物工程研究所)
Comparative Analysis of nnUNet and MedNeXt for Head and Neck Tumor Segmentation in MRI-guided Radiotherapy
Sharif University of Technology(谢里夫理工大学);Institute for AI in Medicine (IKIM), University Medicine Essen(埃森大学医学中心人工智能医学研究所);Center Algoritmi / LASI, University of Minho(米尼奥大学Algoritmi中心/LASI);University Hospital RWTH Aachen(亚琛工业大学附属医院);Cancer Research Center Cologne Essen (CCCE), University Medicine Essen (AöR)(埃森大学医学中心(公法团体)科隆埃森癌症研究中心);German Cancer Consortium (DKTK), Partner Site Essen(德国癌症联盟埃森合作站点);TU Dortmund University(多特蒙德工业大学)
HAMIL-QA: Hierarchical Approach to Multiple Instance Learning for Atrial LGE MRI Quality Assessment
Kahlert School of Computing, University of Utah(犹他大学卡尔特计算机学院);Department of Biomedical Engineering, University of Utah(犹他大学生物医学工程系);Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah(犹他大学诺拉·埃克尔斯·哈里森心血管研究与培训研究所);Johns Hopkins(约翰斯·霍普金斯大学);Division of Cardiology, University of Utah(犹他大学心脏病学系);Department of Radiology and Imaging Sciences, University of Utah(犹他大学放射学与影像科学系);Scientific Computing and Imaging Institute, University of Utah(犹他大学科学计算与影像研究所)
Training Beyond Convergence: Grokking nnU-Net for Glioma Segmentation in Sub-Saharan MRI
Multimedia University(多媒体大学);University of British Columbia(不列颠哥伦比亚大学);McGill University(麦吉尔大学);Montreal Neurological Institute(蒙特利尔神经学研究所);Federal University of Technology Minna(明纳联邦理工大学);Medical Artificial Intelligence Laboratory(医学人工智能实验室);Friedrich-Alexander-Universität(弗里德里希-亚历山大大学)
Comparative Study of Probabilistic Atlas and Deep Learning Approaches for Automatic Brain Tissue Segmentation from MRI Using N4 Bias Field Correction and Anisotropic Diffusion Pre-processing Techniques
University of Girona(赫罗纳大学);University of Burgundy(勃艮第大学);University of Cassino and Southern Lazio(卡西诺和南拉齐奥大学)
Automated surgical planning with nnU-Net: delineation of the anatomy in hepatobiliary phase MRI
The Netherlands Cancer Institute – Antoni van Leeuwenhoek(荷兰癌症研究所 – 安东尼·范·列文虎克);National Center for Tumor Diseases (NCT), NCT/UCC Dresden(国家肿瘤疾病中心(NCT),NCT/UCC 德累斯顿);DKFZ(德国癌症研究中心);Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology(德累斯顿工业大学医学院及卡尔·古斯塔夫·卡鲁斯大学医院);The Centre for Tactile Internet with Human-in-the-Loop (CeTI), TUD Dresden University of Technology(德累斯顿工业大学触觉互联网与人机协同中心);University of Twente(特文特大学)
Multiview Two-Task Recursive Attention Model for Left Atrium and Atrial Scars Segmentation
Anhui University(安徽大学);Royal Brompton Hospital(皇家布朗普顿医院);National Heart & Lung Institute, Imperial College London(帝国理工学院国家心肺研究所);Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences(中国科学院深圳先进技术研究院);University College London(伦敦大学学院);Alan Turing Institute(艾伦·图灵研究所);Imperial College London(帝国理工学院)
AtrialJSQnet: A New Framework for Joint Segmentation and Quantification of Left Atrium and Scars Incorporating Spatial and Shape Information
Fudan University(复旦大学);Shanghai Jiao Tong University(上海交通大学);King’s College London(伦敦国王学院);Technical University Munich(慕尼黑工业大学);Helmholtz Center Munich(慕尼黑亥姆霍兹中心)
A Simple yet Effective Framework for Pre-treatment and Post-treatment Glioma Segmentation Using Multimodal MRI
School of Statistics, East China Normal University(华东师范大学统计学院);Department of Biostatistics, School of Global Public Health, New York University(纽约大学全球公共卫生学院生物统计学系)
Distributionally Robust Segmentation of Abnormal Fetal Brain 3D MRI
School of Biomedical Engineering & Imaging Sciences, King’s College London, UK(伦敦国王学院生物医学工程与成像科学学院);Department of Radiology, University Hospitals Leuven, Belgium(鲁汶大学医院放射科);Institute for Women’s Health, University College London, UK(伦敦大学学院妇女健康研究所);Department of Obstetrics and Gynaecology, University Hospitals Leuven, Belgium(鲁汶大学医院妇产科);Department of Gynecology and Obstetrics, University Hospitals Tanta, Egypt(坦塔大学医院妇产科);Department of Biomedical Imaging and Image-guided Therapy Medical University of Vienna, Austria(维也纳医科大学生物医学成像与图像引导治疗系)
深度神经网络的性能通常随着训练图像的数量而增加。然而,并非所有图像都对提高性能和鲁棒性具有相同的重要性。与非病理性病例相比,在胎儿脑部MRI中,异常会加剧发育中的脑部解剖结构的变异性。少量的异常情况,通常在用于训练的临床数据集中可用,不太可能公平地代表异常发育大脑的丰富变异性。这导致通过最大化平均性能来训练的机器学习系统偏向于非病理情况。这个问题最近被称为隐藏分层。为了适合临床使用,自动分割方法需要可靠地实现高质量的分割结果,也适用于病理病例。在本文中,我们证明了最先进的深度学习管道nnU-Net很难推广到看不见的异常情况。为了缓解这个问题,我们建议训练一个深度神经网络,以最小化数据集上每体积损失分布的百分位数。我们表明,这可以通过使用分布鲁棒优化(DRO)。DRO会自动对性能较低的训练样本进行重新加权,鼓励nnU-Net在所有情况下都能更一致地执行。我们使用368例胎儿脑T2 w MRI数据集验证了我们的方法,其中包括124例开放性脊柱裂病例的MRI和51例其他严重脑发育异常病例的MRI。
BreastSegNet: Multi-label Segmentation of Breast MRI
Department of Biostatistics \& Bioinformatics, Duke University Department of Electrical;Computer Engineering, Duke University Department of Radiology, Duke University Medical Center Department of Computer Science, Duke University
nnSAM2: nnUNet-Enhanced One-Prompt SAM2 for Few-shot Multi-Modality Segmentation and Composition Analysis of Lumbar Paraspinal Muscles
School of Information and Communication Technology, Griffith University(格里菲斯大学信息与通信技术学院);School of Allied Health, Sport and Social Work, Griffith University(格里菲斯大学联合健康、体育与社会工作学院);Center for Neuroplasticity and Pain (CNAP), Department of Health Science and Technology, Aalborg University(奥尔堡大学健康科学与技术系神经可塑性与疼痛中心)
ScarNet: A Novel Foundation Model for Automated Myocardial Scar Quantification from LGE in Cardiac MRI
Northwestern University(西北大学);Feinberg School of Medicine(费林伯格医学院);University of Miami Miller School of Medicine(迈阿密大学米勒医学院);Cedars-Sinai Medical Center(西达赛奈医疗中心)
Topology-Driven Fusion of nnU-Net and MedNeXt for Accurate Brain Tumor Segmentation on Sub-Saharan Africa Dataset
Institute of Engineering, Thapathali Campus, Nepal(尼泊尔工程学院,塔帕塔利校区);Gandaki College of Engineering and Science, Pokhara University, Pokhara, Nepal(加德基工程与科学学院,博克拉大学,博克拉,尼泊尔);Nepal Engineering College, Changunarayan-4, Bhaktapur, Nepal(尼泊尔工程学院,恰纳拉亚纳-4,巴赫塔普尔,尼泊尔);Madan Bhandari University of Science and Technology, Chitlang, Nepal(马丹·班达里科学与技术大学,奇塔朗,尼泊尔);Montreal Neurological Institute, McGill University, Montreal, QC, Canada(蒙特利尔神经研究所,麦吉尔大学,蒙特利尔,魁北克,加拿大);Department of Biomedical Engineering, McGill University(麦吉尔大学生物医学工程系);Medical Artificial Intelligence Laboratory (MAI Lab), Lagos, Nigeria(医学人工智能实验室(MAI实验室),拉各斯,尼日利亚);Department of Physics, Federal University of Technology, Minna, Nigeria(物理系,联邦技术大学,米纳,尼日利亚);Department of Computer Science, Johns Hopkins University(计算机科学系,约翰霍普金斯大学);Department of Radiology and Radiological Science, Johns Hopkins School of Medicine(放射学与放射科学系,约翰霍普金斯医学院);Nepal Applied Mathematics and Informatics Institute for Research (NAAMII), Nepal(尼泊尔应用数学与信息学研究所(NAAMII),尼泊尔);Institute of Engineering, Purbanchal Campus, Nepal(尼泊尔工程学院,普尔班恰尔校区)
MRAnnotator: multi-Anatomy and many-Sequence MRI segmentation of 44 structures
BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai(西奈山伊坎医学院生物医学工程与影像研究所);Department of Diagnostic, Molecular, and Interventional Radiology, Icahn School of Medicine at Mount Sinai(西奈山伊坎医学院诊断、分子与介入放射学系);Rotterdam School of Management, Erasmus University Rotterdam(伊拉斯姆斯大学鹿特丹管理学院);East River Medical Imaging(东河医学影像中心);Department of Radiology, Cornell Medicine(康奈尔医学院放射学系);Windreich Department of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai(西奈山伊坎医学院温赖克人工智能与人类健康系)
Generative Style Transfer for MRI Image Segmentation: A Case of Glioma Segmentation in Sub-Saharan Africa
Institute of Mathematical Science, Strathmore University(斯特拉斯莫尔大学数学科学学院);Faculty of Science and Engineering, University of Hull(赫尔大学科学与工程学院);Technical University of Mombasa(蒙巴萨理工大学);Lawson Health Research Institute(劳森健康研究所);University of British Columbia(不列颠哥伦比亚大学);University of Nairobi(内罗毕大学);University of Cape Town(开普敦大学);Montreal Neurological Institute, McGill University(麦吉尔大学蒙特利尔神经学研究所);Brain Mind Institute, The Aga Khan University(阿迦汗大学脑与心智研究所);Medical Physics Unit, McGill University(麦吉尔大学医学物理部门)
MOIS-SAM2: Exemplar-based Segment Anything Model 2 for multilesion interactive segmentation of neurofibromas in whole-body MRI
Institute for Applied Medical Informatics, Institute of Computational Neuroscience, and Center for Biomedical Artificial Intelligence (bAIome), University Medical Center Hamburg-Eppendorf(应用医学信息学研究所、计算神经科学研究所和生物医学人工智能中心(bAIome)、汉堡医学院中心);Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf(诊断与介入放射学及核医学系、汉堡医学院中心);Department of Neurology, University Medical Center Hamburg-Eppendorf(神经病学系、汉堡医学院中心)
MOIS-SAM2是一种基于示例的Segment Anything Model 2,用于全身体部MRI中神经纤维瘤多病灶交互分割,实现了高精度和可扩展性,支持临床应用。