Multimodal CNN Networks for Brain Tumor Segmentation in MRI: A BraTS 2022 Challenge Solution
Reutlingen University（罗伊特林根大学）；Menoufia University（梅努菲亚大学）；Karlsruhe Institute of Technology（卡尔斯鲁厄理工学院）
Ramy A. Zeineldin, Mohamed E. Karar, Oliver Burgert, Franziska Mathis-Ullrich
备注：
Accepted in BraTS 2022 (as part of the BrainLes workshop proceedings distributed by Springer LNCS). arXiv admin note: text overlap with arXiv:2112.06554
Automatic segmentation is essential for the brain tumor diagnosis, disease prognosis, and follow-up therapy of patients with gliomas. Still, accurate detection of gliomas and their sub-regions in multimodal MRI is very challenging due to the variety of scanners and imaging protocols. Over the last years, the BraTS Challenge has provided a large number of multi-institutional MRI scans as a benchmark for glioma segmentation algorithms. This paper describes our contribution to the BraTS 2022 Continuous Evaluation challenge. We propose a new ensemble of multiple deep learning frameworks namely, DeepSeg, nnU-Net, and DeepSCAN for automatic glioma boundaries detection in pre-operative MRI. It is worth noting that our ensemble models took first place in the final evaluation on the BraTS testing dataset with Dice scores of 0.9294, 0.8788, and 0.8803, and Hausdorf distance of 5.23, 13.54, and 12.05, for the whole tumor, tumor core, and enhancing tumor, respectively. Furthermore, the proposed ensemble method ranked first in the final ranking on another unseen test dataset, namely Sub-Saharan Africa dataset, achieving mean Dice scores of 0.9737, 0.9593, and 0.9022, and HD95 of 2.66, 1.72, 3.32 for the whole tumor, tumor core, and enhancing tumor, respectively. The docker image for the winning submission is publicly available at (https://hub.docker.com/r/razeineldin/camed22).
Training a deep neural network is an optimization problem with four main ingredients: the design of the deep neural network, the per-sample loss function, the population loss function, and the optimizer. However, methods developed to compete in recent BraTS challenges tend to focus only on the design of deep neural network architectures, while paying less attention to the three other aspects. In this paper, we experimented with adopting the opposite approach. We stuck to a generic and state-of-the-art 3D U-Net architecture and experimented with a non-standard per-sample loss function, the gene…
Cancer of the brain is deadly and requires careful surgical segmentation. The brain tumors were segmented using U-Net using a Convolutional Neural Network (CNN). When looking for overlaps of necrotic, edematous, growing, and healthy tissue, it might be hard to get relevant information from the images. The 2D U-Net network was improved and trained with the BraTS datasets to find these four areas. U-Net can set up many encoder and decoder routes that can be used to get information from images that can be used in different ways. To reduce computational time, we use image segmentation to exclude i…
A New Logic For Pediatric Brain Tumor Segmentation
1 Northwestern University, Feinberg School of Medicine, Chicago IL, USA 2 Children’s National Hospital, Sheikh Zayed Institute for Pediatric Surgical Innovation, Washington, DC, USA 3 Ann \& Robert H Lurie Children's Hospital of Chicago, Chicago, IL, USA
Frequency-Aware Ensemble Learning for BraTS 2025 Pediatric Brain Tumor Segmentation
Institute of Natural Sciences, School of Mathematical Sciences, MOE-LSC, Shanghai Jiao Tong University（自然科学院、数学科学学院、MOE-LSC、上海交通大学）；Department of Radiology, Huashan Hospital, Fudan University（放射科、华山医院、复旦大学）；Department of Neurosurgery, Huashan Hospital, Fudan University（神经外科、华山医院、复旦大学）
Reutlingen University（罗伊特林根大学）；Menoufia University（梅努菲亚大学）；Karlsruhe Institute of Technology（卡尔斯鲁厄理工学院）
Glioblastomas are the most aggressive fast-growing primary brain cancer which originate in the glial cells of the brain. Accurate identification of the malignant brain tumor and its sub-regions is still one of the most challenging problems in medical image segmentation. The Brain Tumor Segmentation Challenge (BraTS) has been a popular benchmark for automatic brain glioblastomas segmentation algorithms since its initiation. In this year, BraTS 2021 challenge provides the largest multi-parametric (mpMRI) dataset of 2,000 pre-operative patients. In this paper, we propose a new aggregation of two …
Topology-Driven Fusion of nnU-Net and MedNeXt for Accurate Brain Tumor Segmentation on Sub-Saharan Africa Dataset
Institute of Engineering, Thapathali Campus, Nepal（尼泊尔工程学院，塔帕塔利校区）；Gandaki College of Engineering and Science, Pokhara University, Pokhara, Nepal（加德基工程与科学学院，博克拉大学，博克拉，尼泊尔）；Nepal Engineering College, Changunarayan-4, Bhaktapur, Nepal（尼泊尔工程学院，恰纳拉亚纳-4，巴赫塔普尔，尼泊尔）；Madan Bhandari University of Science and Technology, Chitlang, Nepal（马丹·班达里科学与技术大学，奇塔朗，尼泊尔）；Montreal Neurological Institute, McGill University, Montreal, QC, Canada（蒙特利尔神经研究所，麦吉尔大学，蒙特利尔，魁北克，加拿大）；Department of Biomedical Engineering, McGill University（麦吉尔大学生物医学工程系）；Medical Artificial Intelligence Laboratory (MAI Lab), Lagos, Nigeria（医学人工智能实验室（MAI实验室），拉各斯，尼日利亚）；Department of Physics, Federal University of Technology, Minna, Nigeria（物理系，联邦技术大学，米纳，尼日利亚）；Department of Computer Science, Johns Hopkins University（计算机科学系，约翰霍普金斯大学）；Department of Radiology and Radiological Science, Johns Hopkins School of Medicine（放射学与放射科学系，约翰霍普金斯医学院）；Nepal Applied Mathematics and Informatics Institute for Research (NAAMII), Nepal（尼泊尔应用数学与信息学研究所（NAAMII），尼泊尔）；Institute of Engineering, Purbanchal Campus, Nepal（尼泊尔工程学院，普尔班恰尔校区）
Indiana University School of Medicine（印第安纳大学医学院）；Indiana University（印第安纳大学）；MLCommons；Mayo Clinic（梅奥诊所）；Sage Bionetworks；Perelman School of Medicine, University of Pennsylvania（宾夕法尼亚大学佩雷尔曼医学院）；Feinberg School of Medicine, Northwestern University（西北大学范伯格医学院）；University of Verona（维罗纳大学）；University of Texas MD Anderson Cancer Center（德克萨斯大学 MD 安德森癌症中心）；Duke University School of Medicine（杜克大学医学院）；Duke University Medical School（杜克大学医学院）；Johns Hopkins University School Of Medicine（约翰霍普金斯大学医学院）
The Brain Tumor Segmentation (BraTS) Challenge: Local Synthesis of Healthy Brain Tissue via Inpainting
Helmholtz AI, Germany（亥姆霍兹人工智能研究所）；Technical University of Munich, Germany（慕尼黑工业大学）；Helmholtz Munich, Germany（亥姆霍兹慕尼黑中心）；University of Zurich, Switzerland（苏黎世大学）；Klinikum Rechts der Isar, Munich, Germany（慕尼黑右岸医院）；SETLabs Research GmbH, Healthcare Technologies, Munich, Germany（SETLabs研究有限公司）；Ludwig Maximilian University, Munich, Germany（路德维希马克西米利安慕尼黑大学）
Pakistan Institute of Engineering and Applied Sciences (PIEAS)（巴基斯坦工程与应用科学学院）；Ibadat International University（伊巴达特国际大学）；University of Engineering and Applied Science (UEAS)（工程与应用科学大学）
Brain tumor classification is crucial for clinical analysis and an effective treatment plan to cure patients. Deep learning models help radiologists to accurately and efficiently analyze tumors without manual intervention. However, brain tumor analysis is challenging because of its complex structure, texture, size, location, and appearance. Therefore, a novel deep residual and regional-based Res-BRNet Convolutional Neural Network (CNN) is developed for effective brain tumor (Magnetic Resonance Imaging) MRI classification. The developed Res-BRNet employed Regional and boundary-based operations …
We apply an ensemble of modified TransBTS, nnU-Net, and a combination of both for the segmentation task of the BraTS 2021 challenge. In fact, we change the original architecture of the TransBTS model by adding Squeeze-and-Excitation blocks, an increasing number of CNN layers, replacing positional encoding in Transformer block with a learnable Multilayer Perceptron (MLP) embeddings, which makes Transformer adjustable to any input size during inference. With these modifications, we are able to largely improve TransBTS performance. Inspired by a nnU-Net framework we decided to combine it with our…
Future Processing（Future Processing公司）；Silesian University of Technology（西里西亚工业大学）；Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology（玛丽亚·斯克沃多夫斯卡-居里纪念癌症中心与肿瘤研究所）；Feedback Medical Ltd.（Feedback Medical有限公司）
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) plays an important role in diagnosis and grading of brain tumor. Although manual DCE biomarker extraction algorithms boost the diagnostic yield of DCE-MRI by providing quantitative information on tumor prognosis and prediction, they are time-consuming and prone to human error. In this paper, we propose a fully-automated, end-to-end system for DCE-MRI analysis of brain tumors. Our deep learning-powered technique does not require any user interaction, it yields reproducible results, and it is rigorously validated against benchmark (B…
The ASNR-MICCAI Brain Tumor Segmentation (BraTS) Challenge 2023: Intracranial Meningioma
Duke University Medical Center（杜克大学医学中心）；Crestview Radiology（远景放射科）；Perelman School of Medicine, University of Pennsylvania（宾夕法尼亚大学佩雷尔曼医学院）；University of Pennsylvania（宾夕法尼亚大学）；Missouri University（密苏里大学）；Children's National Hospital（国家儿童医院）；George Washington University（乔治华盛顿大学）；Sage Bionetworks（赛智生物网络公司）；University of California San Francisco（加州大学旧金山分校）；Mayo Clinic（梅奥诊所）；Technical University Munich（慕尼黑工业大学）；Technical University of Munich（慕尼黑工业大学）；Children’s Hospital of Philadelphia（费城儿童医院）；National Cancer Institute, National Institutes of Health（美国国立卫生研究院国家癌症研究所）；Massachusetts General Hospital（马萨诸塞州总医院）；U.S. Food and Drug Administration（美国食品药品监督管理局）；Helmholtz Munich（亥姆霍兹慕尼黑中心）；Technical University of Denmark（丹麦技术大学）；University of Zurich（苏黎世大学）；Thomas Jefferson University（托马斯杰斐逊大学）；Yale University（耶鲁大学）；Booz Allen Hamilton（博思艾伦咨询公司）；Mercy Catholic Medical Center（仁慈天主教医疗中心）；Northwestern University（西北大学）；McGill University（麦吉尔大学）；University of San Diego（圣地亚哥大学）
A Unified Attention U-Net Framework for Cross-Modality Tumor Segmentation in MRI and CT
Department of Computer Science, New Mexico State University（计算机科学系，新墨西哥州立大学）；Department of Plant and Environmental Sciences, New Mexico State University（植物与环境科学系，新墨西哥州立大学）
University at Buffalo, The State University of New York（纽约州立大学布法罗分校）
Brain Tumor Segmentation from magnetic resonance imaging (MRI) is a critical technique for early diagnosis. However, rather than having complete four modalities as in BraTS dataset, it is common to have missing modalities in clinical scenarios. We design a brain tumor segmentation algorithm that is robust to the absence of any modality. Our network includes a channel-independent encoding path and a feature-fusion decoding path. We use self-supervised training through channel dropout and also propose a novel domain adaptation method on feature maps to recover the information from the missing ch…
University of Engineering & Technology, Taxila（塔克西拉工程技术大学）
Detection of brain tumor using a segmentation based approach is critical in cases, where survival of a subject depends on an accurate and timely clinical diagnosis. Gliomas are the most commonly found tumors having irregular shape and ambiguous boundaries, making them one of the hardest tumors to detect. The automation of brain tumor segmentation remains a challenging problem mainly due to significant variations in its structure. An automated brain tumor segmentation algorithm using deep convolutional neural network (DCNN) is presented in this paper. A patch based approach along with an incept…
Training the next generation of physicians for artificial intelligence-assisted clinical neuroradiology: ASNR MICCAI Brain Tumor Segmentation (BraTS) 2025 Lighthouse Challenge education platform
Children's Hospital of Philadelphia（费城儿童医院）；Multiprofile Hospital for Active Treatment in Neurology and Psychiatry 'St. Naum'（圣瑙姆神经病学与精神病学多学科积极治疗医院）；Jena University Hospital, Friedrich Schiller University Jena（耶拿大学医院，弗里德里希·席勒耶拿大学）；University of Tubingen（蒂宾根大学）；Charité – Universitätsmedizin Berlin（柏林夏里特医学院）；Hospital of the University of Pennsylvania（宾夕法尼亚大学医院）；Teesside University（提赛德大学）
Research & Development Institute of Northwestern Polytechnical University in Shenzhen（西北工业大学深圳研究院）；Northwestern Polytechnical University（西北工业大学）；University of Pittsburgh（匹兹堡大学）；University of Sydney（悉尼大学）；JD Finance America Corporation（京东金融美国公司）
In this paper, we propose a Hybrid High-resolution and Non-local Feature Network (H2NF-Net) to segment brain tumor in multimodal MR images. Our H2NF-Net uses the single and cascaded HNF-Nets to segment different brain tumor sub-regions and combines the predictions together as the final segmentation. We trained and evaluated our model on the Multimodal Brain Tumor Segmentation Challenge (BraTS) 2020 dataset. The results on the test set show that the combination of the single and cascaded models achieved average Dice scores of 0.78751, 0.91290, and 0.85461, as well as Hausdorff distances ($95\%$…
Brain tumor segmentation is a critical task for patient's disease management. In order to automate and standardize this task, we trained multiple U-net like neural networks, mainly with deep supervision and stochastic weight averaging, on the Multimodal Brain Tumor Segmentation Challenge (BraTS) 2020 training dataset. Two independent ensembles of models from two different training pipelines were trained, and each produced a brain tumor segmentation map. These two labelmaps per patient were then merged, taking into account the performance of each ensemble for specific tumor subregions. Our perf…
This paper proposes an adversarial learning based training approach for brain tumor segmentation task. In this concept, the 3D segmentation network learns from dual reciprocal adversarial learning approaches. To enhance the generalization across the segmentation predictions and to make the segmentation network robust, we adhere to the Virtual Adversarial Training approach by generating more adversarial examples via adding some noise on original patient data. By incorporating a critic that acts as a quantitative subjective referee, the segmentation network learns from the uncertainty informatio…
German Cancer Research Center (DKFZ)（德国癌症研究中心）；Heidelberg University Hospital（海德堡大学医院）
We apply nnU-Net to the segmentation task of the BraTS 2020 challenge. The unmodified nnU-Net baseline configuration already achieves a respectable result. By incorporating BraTS-specific modifications regarding postprocessing, region-based training, a more aggressive data augmentation as well as several minor modifications to the nnUNet pipeline we are able to improve its segmentation performance substantially. We furthermore re-implement the BraTS ranking scheme to determine which of our nnU-Net variants best fits the requirements imposed by it. Our final ensemble took the first place in the…
Automatic MRI brain tumor segmentation is of vital importance for the disease diagnosis, monitoring, and treatment planning. In this paper, we propose a two-stage encoder-decoder based model for brain tumor subregional segmentation. Variational autoencoder regularization is utilized in both stages to prevent the overfitting issue. The second-stage network adopts attention gates and is trained additionally using an expanded dataset formed by the first-stage outputs. On the BraTS 2020 validation dataset, the proposed method achieves the mean Dice score of 0.9041, 0.8350, and 0.7958, and Hausdorf…
Convolutional Neural Networks (CNNs) have demonstrated state-of-the-art performance in medical image segmentation tasks. A common feature in most top-performing CNNs is an encoder-decoder architecture inspired by the U-Net. For multi-region brain tumor segmentation, 3D U-Net architecture and its variants provide the most competitive segmentation performances. In this work, we propose an interesting extension of the standard 3D U-Net architecture, specialized for brain tumor segmentation. The proposed network, called E1D3 U-Net, is a one-encoder, three-decoder fully-convolutional neural network…
Multimodal brain tumor segmentation challenge (BraTS) brings together researchers to improve automated methods for 3D MRI brain tumor segmentation. Tumor segmentation is one of the fundamental vision tasks necessary for diagnosis and treatment planning of the disease. Previous years winning methods were all deep-learning based, thanks to the advent of modern GPUs, which allow fast optimization of deep convolutional neural network architectures. In this work, we explore best practices of 3D semantic segmentation, including conventional encoder-decoder architecture, as well combined loss functio…
We propose an optimized U-Net architecture for a brain tumor segmentation task in the BraTS21 challenge. To find the optimal model architecture and the learning schedule, we have run an extensive ablation study to test: deep supervision loss, Focal loss, decoder attention, drop block, and residual connections. Additionally, we have searched for the optimal depth of the U-Net encoder, number of convolutional channels and post-processing strategy. Our method won the validation phase and took third place in the test phase. We have open-sourced the code to reproduce our BraTS21 submission at the N…
Another year of the multimodal brain tumor segmentation challenge (BraTS) 2021 provides an even larger dataset to facilitate collaboration and research of brain tumor segmentation methods, which are necessary for disease analysis and treatment planning. A large dataset size of BraTS 2021 and the advent of modern GPUs provide a better opportunity for deep-learning based approaches to learn tumor representation from the data. In this work, we maintained an encoder-decoder based segmentation network, but focused on a modification of network training process that minimizes redundancy under perturb…
The Brain Tumor Segmentation (BraTS) Challenge 2023: Focus on Pediatrics (CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs)
Center for Data-Driven Discovery in Biomedicine (D3b), Children’s Hospital of Philadelphia（费城儿童医院生物医学数据驱动发现中心）；University of Pennsylvania（宾夕法尼亚大学）；Center for AI & Data Science for Integrated Diagnostics (AI2D)（综合诊断人工智能与数据科学中心）；Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania（宾夕法尼亚大学生物医学图像计算与分析中心）；Sheikh Zayed Institute for Pediatric Surgical Innovation, Children’s National Hospital（儿童医院谢赫·扎耶德儿科外科创新研究所）；Thomas Jefferson University Hospital（托马斯杰斐逊大学医院）；Sage Bionetworks；Montreal Neurological Institute (MNI), McGill University（麦吉尔大学蒙特利尔神经学研究所）；Perelman School of Medicine, University of Pennsylvania（宾夕法尼亚大学佩雷尔曼医学院）；University of Southern California（南加州大学）；Duke University Medical Center（杜克大学医学中心）；Mayo Clinic（梅奥诊所）；Center for Global Health, Perelman School of Medicine, University of Pennsylvania（宾夕法尼亚大学佩雷尔曼医学院全球健康中心）；Technical University of Munich（慕尼黑工业大学）；TranslaTUM - Central Institute for Translational Cancer Research, Technical University of Munich（慕尼黑工业大学转化肿瘤学研究中心（TranslaTUM））；National Cancer Institute（美国国家癌症 Institute）
QU-BraTS: MICCAI BraTS 2020 Challenge on Quantifying Uncertainty in Brain Tumor Segmentation - Analysis of Ranking Scores and Benchmarking Results
McGill University（麦吉尔大学）；University of Oxford（牛津大学）；University of Pennsylvania（宾夕法尼亚大学）；Perelman School of Medicine at the University of Pennsylvania（宾夕法尼亚大学佩雷尔曼医学院）；University of Bern（伯尔尼大学）；Bern University Hospital（伯尔尼大学医院）；University of Texas Southwestern Medical Center（德克萨斯大学西南医学中心）；Universidad de los Andes（洛斯安第斯大学）；Imperial College London（帝国理工学院）；Indian Statistical Institute（印度统计研究所）；University of Calcutta（加尔各答大学）；Uppsala University（乌普萨拉大学）；The University of Pittsburgh Medical Center（匹兹堡大学医学中心）；Inserm（法国国家健康与医学研究院）；University of Auckland（奥克兰大学）；Auckland City Hospital（奥克兰市医院）；Massachusetts General Hospital（麻省总医院）；Massachusetts Institute of Technology（麻省理工学院）；EPITA Research and Development Laboratory (LRDE)（EPITA研发实验室）；Old Dominion University（老道明大学）；University of Girona（赫罗纳大学）；University of Tehran（德黑兰大学）；University of Nottingham（诺丁汉大学）；NVIDIA（英伟达）；University of Virginia（弗吉尼亚大学）；Indian Institute of Technology - Jodhpur（印度理工学院焦特布尔分校）
Automated Ensemble-Based Segmentation of Adult Brain Tumors: A Novel Approach Using the BraTS AFRICA Challenge Data
Manning College of Information and Computer Sciences, University of Massachusetts Amherst（马萨诸塞大学阿默斯特分校曼宁信息与计算机科学学院）；Baystate Medical Center（贝斯州医疗中心）；UMass Chan Medical School - Baystate Campus（马萨诸塞大学陈医学院贝斯州校区）
本文面向撒哈拉以南非洲成人患者，提出融合 UNet3D、ONet3D、SphereNet3D 及改进损失函数的十一模型集成脑肿瘤分割方法，在 BraTS AFRICA 数据上取得优于单模型的分割性能。
multiPI-TransBTS: A Multi-Path Learning Framework for Brain Tumor Image Segmentation Based on Multi-Physical Information
Chongqing University of Posts and Telecommunications（重庆邮电大学）；Chongqing Engineering Research Center of Software Quality Assurance, Testing and Assessment（重庆市软件质量保证与测评工程技术研究中心）
Macquarie University（麦考瑞大学）；Australian Institute of Health Innovation（澳大利亚健康创新研究院）
Pre-processing and Data Augmentation play an important role in Deep Convolutional Neural Networks (DCNN). Whereby several methods aim for standardization and augmentation of the dataset, we here propose a novel method aimed to feed DCNN with spherical space transformed input data that could better facilitate feature learning compared to standard Cartesian space images and volumes. In this work, the spherical coordinates transformation has been applied as a preprocessing method that, used in conjunction with normal MRI volumes, improves the accuracy of brain tumor segmentation and patient overa…
Vingroup Big Data Institute (VinBigdata)（越南 VinBigdata 大数据研究院）；Hanoi University of Science and Technology (HUST)（河内科技大学）；University of Engineering and Technology (UET), VNU（越南国立大学工程技术大学）
Brain tumor segmentation plays an essential role in medical image analysis. In recent studies, deep convolution neural networks (DCNNs) are extremely powerful to tackle tumor segmentation tasks. We propose in this paper a novel training method that enhances the segmentation results by adding an additional classification branch to the network. The whole network was trained end-to-end on the Multimodal Brain Tumor Segmentation Challenge (BraTS) 2020 training dataset. On the BraTS's validation set, it achieved an average Dice score of 78.43%, 89.99%, and 84.22% respectively for the enhancing tumo…
Indian Institute of Technology Madras（印度理工学院马德拉斯分校）；Intel Technology India Pvt. Ltd（英特尔技术印度私人有限公司）
We utilize 3-D fully convolutional neural networks (CNN) to segment gliomas and its constituents from multimodal Magnetic Resonance Images (MRI). The architecture uses dense connectivity patterns to reduce the number of weights and residual connections and is initialized with weights obtained from training this model with BraTS 2018 dataset. Hard mining is done during training to train for the difficult cases of segmentation tasks by increasing the dice similarity coefficient (DSC) threshold to choose the hard cases as epoch increases. On the BraTS2020 validation data (n = 125), this architect…
Automatic segmentation of brain tumors is an essential but challenging step for extracting quantitative imaging biomarkers for accurate tumor detection, diagnosis, prognosis, treatment planning and assessment. Multimodal Brain Tumor Segmentation Challenge 2020 (BraTS 2020) provides a common platform for comparing different automatic algorithms on multi-parametric Magnetic Resonance Imaging (mpMRI) in tasks of 1) Brain tumor segmentation MRI scans; 2) Prediction of patient overall survival (OS) from pre-operative MRI scans; 3) Distinction of true tumor recurrence from treatment related effects …
Parameter-efficient Fine-tuning for improved Convolutional Baseline for Brain Tumor Segmentation in Sub-Saharan Africa Adult Glioma Dataset
Nepal Research and Collaboration Center (NRCC)（尼泊尔研究与合作中心）；Birendra Multiple Campus, Tribhuvan University（特里布万大学比伦德拉多校区）；Institute of Engineering, Purbanchal Campus, Tribhuvan University（特里布万大学普尔班查尔校区工程学院）；Bhaktapur Multiple Campus, Tribhuvan University（特里布万大学巴克塔普尔多校区）；Gandaki College of Engineering and Science, Pokhara University（博卡拉大学甘达基工程与科学学院）；McGill University（麦吉尔大学）；Lawson Health Research Institute（劳森健康研究所）；Medical Artificial Intelligence Laboratory (MAI Lab), Lagos（拉各斯医学人工智能实验室）；University of British Columbia（不列颠哥伦比亚大学）；Montreal Neurological Institute, McGill University（麦吉尔大学蒙特利尔神经学研究所）
Tumor Location-weighted MRI-Report Contrastive Learning: A Framework for Improving the Explainability of Pediatric Brain Tumor Diagnosis
The Hospital for Sick Children（病童医院）；University of Toronto（多伦多大学）；Vector Institute for Artificial Intelligence（矢量人工智能研究所）；University Hospital Augsburg（奥格斯堡大学医院）
Gliomas are among the most aggressive and deadly brain tumors. This paper details the proposed Deep Neural Network architecture for brain tumor segmentation from Magnetic Resonance Images. The architecture consists of a cascade of three Deep Layer Aggregation neural networks, where each stage elaborates the response using the feature maps and the probabilities of the previous stage, and the MRI channels as inputs. The neuroimaging data are part of the publicly available Brain Tumor Segmentation (BraTS) 2020 challenge dataset, where we evaluated our proposal in the BraTS 2020 Validation and Tes…
The Brain Tumor Segmentation in Pediatrics (BraTS-PEDs) Challenge: Focus on Pediatrics (CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs)
Center for Data-Driven Discovery in Biomedicine (D3b)（生物医学数据驱动发现中心）；Children’s Hospital of Philadelphia（费城儿童医院）；Department of Neurosurgery, University of Pennsylvania（宾夕法尼亚大学神经外科）；Center for AI & Data Science for Integrated Diagnostics (AI2D)（综合诊断人工智能与数据科学中心）；Center for Biomedical Image Computing and Analytics (CBICA)（生物医学图像计算与分析中心）；Sheikh Zayed Institute for Pediatric Surgical Innovation, Children’s National Hospital（儿童医院谢赫·扎耶德儿科外科创新研究所）；Sage Bionetworks（赛基生物网络公司）；Medical Artificial Intelligence (MAI) Lab, Crestview Radiology（Crestview放射科医学人工智能实验室）；Montreal Neurological Institute (MNI), McGill University（麦吉尔大学蒙特利尔神经学研究所）；Department of Radiology, Perelman School of Medicine, University of Pennsylvania（宾夕法尼亚大学佩雷尔曼医学院放射科）；Division of Computational Pathology, Department of Pathology and Laboratory Medicine, Indiana University School of Medicine（印第安纳大学医学院病理学与实验医学系计算病理学分部）；Department of Neurosurgery at the University of Southern California（南加州大学神经外科）；Department of Radiology, Duke University Medical Center（杜克大学医学中心放射科）；Mayo Clinic（梅奥诊所）；Center for Global Health, Perelman School of Medicine, University of Pennsylvania（宾夕法尼亚大学佩雷尔曼医学院全球健康中心）；Department of Informatics, Technical University Munich（慕尼黑工业大学信息学系）；TranslaTUM - Central Institute for Translational Cancer Research, Technical University of Munich（慕尼黑工业大学TranslaTUM转化癌症研究中心）
How We Won BraTS-SSA 2025: Brain Tumor Segmentation in the Sub-Saharan African Population Using Segmentation-Aware Data Augmentation and Model Ensembling
Kwame Nkrumah University of Science and Technology（卡布雷·克鲁马大学科学与技术大学）；University of Cape Coast（科克斯特大学）；University of Toronto（多伦多大学）；Department of Biomedical Engineering, McGill University（麦吉尔大学生物医学工程系）；Department of Physics, Federal University of Technology（联邦技术大学物理系）
Reutlingen University（罗伊特林根大学）；Menoufia University（梅努菲亚大学）；Karlsruhe Institute of Technology（卡尔斯鲁厄理工学院）
Reliable and accurate registration of patient-specific brain magnetic resonance imaging (MRI) scans containing pathologies is challenging due to tissue appearance changes. This paper describes our contribution to the Registration of the longitudinal brain MRI task of the Brain Tumor Sequence Registration Challenge 2022 (BraTS-Reg 2022). We developed an enhanced unsupervised learning-based method that extends the iRegNet. In particular, incorporating an unsupervised learning-based paradigm as well as several minor modifications to the network pipeline, allows the enhanced iRegNet method to achi…
The research on developing CNN-based fully-automated Brain-Tumor-Segmentation systems has been progressed rapidly. For the systems to be applicable in practice, a good The research on developing CNN-based fully-automated Brain-Tumor-Segmentation systems has been progressed rapidly. For the systems to be applicable in practice, a good processing quality and reliability are the must. Moreover, for wide applications of such systems, a minimization of computation complexity is desirable, which can also result in a minimization of randomness in computation and, consequently, a better performance co…
