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arXiv 2501.04734eess.IVcs.AIcs.LGphysics.med-ph
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用于 MRI 图像分割的生成式风格迁移:撒哈拉以南非洲胶质瘤分割案例

Generative Style Transfer for MRI Image Segmentation: A Case of Glioma Segmentation in Sub-Saharan Africa

Institute of Mathematical Science, Strathmore University(斯特拉斯莫尔大学数学科学学院);Faculty of Science and Engineering, University of Hull(赫尔大学科学与工程学院);Technical University of Mombasa(蒙巴萨理工大学);Lawson Health Research Institute(劳森健康研究所);University of British Columbia(不列颠哥伦比亚大学);University of Nairobi(内罗毕大学);University of Cape Town(开普敦大学);Montreal Neurological Institute, McGill University(麦吉尔大学蒙特利尔神经学研究所);Brain Mind Institute, The Aga Khan University(阿迦汗大学脑与心智研究所);Medical Physics Unit, McGill University(麦吉尔大学医学物理部门)

Rancy Chepchirchir, Jill Sunday, Raymond Confidence, Dong Zhang, Talha Chaudhry, Udunna C. Anazodo, Kendi Muchungi, Yujing Zou

AI总结:

针对撒哈拉以南非洲低质量 MRI 场景,研究评估领域偏移并比较 nnU-Net 的 3D/2D 模型,提出微调与神经风格迁移数据增强以提升胶质瘤分割性能。

摘要:

在撒哈拉以南非洲(SSA),较低质量磁共振成像(MRI)技术的使用引发了人们对机器学习方法在临床任务中适用性的疑问。本研究旨在采用一种三管齐下的方法,为 SSA 人群提供一种稳健的、基于深度学习的脑肿瘤分割(BraTS)方法。首先,研究考察了来自 SSA 训练数据的领域偏移对模型效能的影响,结果显示不存在显著影响。其次,使用 nnU-Net 框架对 3D 与 2D 全分辨率模型进行的比较分析表明,两种模型表现相近;二者均训练 300 个 epoch,并取得 0.93 的五折交叉验证分数。最后,针对在 SSA 验证中观察到的、与相对更大的 BraTS 胶质瘤(GLI)验证集相比存在的性能差距,研究提出两种策略:在训练 300 个 epoch 的 GLI+SSA 最佳预训练 2D fullres 模型上对 SSA 病例进行微调,以及为 SSA 病例引入一种新颖的、基于神经风格迁移的数据增强技术。本调查凸显了在 SSA 独特医疗环境中改进脑肿瘤预测的潜力。

英文摘要:

In Sub-Saharan Africa (SSA), the utilization of lower-quality Magnetic Resonance Imaging (MRI) technology raises questions about the applicability of machine learning methods for clinical tasks. This study aims to provide a robust deep learning-based brain tumor segmentation (BraTS) method tailored for the SSA population using a threefold approach. Firstly, the impact of domain shift from the SSA training data on model efficacy was examined, revealing no significant effect. Secondly, a comparative analysis of 3D and 2D full-resolution models using the nnU-Net framework indicates similar performance of both the models trained for 300 epochs achieving a five-fold cross-validation score of 0.93. Lastly, addressing the performance gap observed in SSA validation as opposed to the relatively larger BraTS glioma (GLI) validation set, two strategies are proposed: fine-tuning SSA cases using the GLI+SSA best-pretrained 2D fullres model at 300 epochs, and introducing a novel neural style transfer-based data augmentation technique for the SSA cases. This investigation underscores the potential of enhancing brain tumor prediction within SSA's unique healthcare landscape.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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