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arXiv 2510.14831cs.CV

扩展肿瘤分割规模:来自真实数据与合成数据的最佳经验

Scaling Tumor Segmentation: Best Lessons from Real and Synthetic Data

Johns Hopkins University(约翰霍普金斯大学);UCAS-Terminus AI Lab, University of Chinese Academy of Sciences(中国科学院大学Terminus AI实验室);Hong Kong Polytechnic University(香港理工大学);University of Cambridge(剑桥大学);Sichuan University(四川大学);Shanghai Jiao Tong University(上海交通大学);Shanghai AI Laboratory(上海人工智能实验室);Qilu Hospital of Shandong University(山东大学齐鲁医院);Westlake University(西湖大学)

Qi Chen, Xinze Zhou, Chen Liu, Hao Chen, Wenxuan Li, Zekun Jiang, Ziyan Huang, Yuxuan Zhao, Dexin Yu, Junjun He, Yefeng Zheng, Ling Shao, Alan Yuille, Zongwei Zhou

AI总结:

针对肿瘤分割AI受限于标注数据规模的问题,研究发现在1500例后性能停止提升,但结合合成数据仅需500例真实数据即可达到同等效果,据此构建了大规模数据集AbdomenAtlas 2.0,显著提升了模型在分布内外测试中的分割性能。

摘要:

用于肿瘤分割的 AI 受限于缺乏大规模的逐体素标注数据集,这些数据集难以创建且需要医学专家参与。在我们专有的包含 3,000 例标注胰腺肿瘤扫描的 JHH 数据集中,我们发现 AI 性能在 1,500 例扫描后停止提升。借助合成数据,我们仅使用 500 例真实扫描便达到了相同的性能。这一发现表明,合成数据能够使数据缩放定律变得更陡峭,从而实现比仅使用真实数据更高效的模型训练。受这些经验启发,我们创建了 AbdomenAtlas 2.0——这是一个包含 10,135 例 CT 扫描的数据集,在六个器官(胰腺、肝脏、肾脏、结肠、食管和子宫)中逐体素手动标注了总计 15,130 个肿瘤实例,并包含 5,893 例对照扫描。该数据集由 23 位专家放射科医生标注,比现有的公开肿瘤数据集大几个数量级。虽然我们仍在继续扩展该数据集,但当前版本的 AbdomenAtlas 2.0 已经提供了一个坚实的基础——基于 JHH 数据集的经验——用于训练 AI 对六个器官中的肿瘤进行分割。相较于公开数据集,它取得了显著改进,在分布内测试中获得了 +7% 的 DSC 提升,在分布外测试中获得了 +16% 的提升。

英文摘要:

AI for tumor segmentation is limited by the lack of large, voxel-wise annotated datasets, which are hard to create and require medical experts. In our proprietary JHH dataset of 3,000 annotated pancreatic tumor scans, we found that AI performance stopped improving after 1,500 scans. With synthetic data, we reached the same performance using only 500 real scans. This finding suggests that synthetic data can steepen data scaling laws, enabling more efficient model training than real data alone. Motivated by these lessons, we created AbdomenAtlas 2.0--a dataset of 10,135 CT scans with a total of 15,130 tumor instances per-voxel manually annotated in six organs (pancreas, liver, kidney, colon, esophagus, and uterus) and 5,893 control scans. Annotated by 23 expert radiologists, it is several orders of magnitude larger than existing public tumor datasets. While we continue expanding the dataset, the current version of AbdomenAtlas 2.0 already provides a strong foundation--based on lessons from the JHH dataset--for training AI to segment tumors in six organs. It achieves notable improvements over public datasets, with a +7% DSC gain on in-distribution tests and +16% on out-of-distribution tests.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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