Self-supervised Tumor Segmentation through Layer Decomposition
Cooperative Medianet Innovation Center, Shanghai Jiao Tong University（上海交通大学协同媒体创新中心）；Shanghai AI Laboratory（上海人工智能实验室）；VGG, University of Oxford（牛津大学VGG）；Huawei Cloud & AI（华为云与人工智能）
In this paper, we target self-supervised representation learning for zero-shot tumor segmentation. We make the following contributions: First, we advocate a zero-shot setting, where models from pre-training should be directly applicable for the downstream task, without using any manual annotations. Second, we take inspiration from "layer-decomposition", and innovate on the training regime with simulated tumor data. Third, we conduct extensive ablation studies to analyse the critical components in data simulation, and validate the necessity of different proxy tasks. We demonstrate that, with sufficient texture randomization in simulation, model trained on synthetic data can effortlessly generalise to segment real tumor data. Forth, our approach achieves superior results for zero-shot tumor segmentation on different downstream datasets, BraTS2018 for brain tumor segmentation and LiTS2017 for liver tumor segmentation. While evaluating the model transferability for tumor segmentation under a low-annotation regime, the proposed approach also outperforms all existing self-supervised approaches, opening up the usage of self-supervised learning in practical scenarios.
Data Science Institute, Imperial College London（伦敦帝国理工学院数据科学研究所）；National Heart and Lung Institute, Imperial College London（伦敦帝国理工学院国家心肺研究所）
A major challenge in brain tumor treatment planning and quantitative evaluation is determination of the tumor extent. The noninvasive magnetic resonance imaging (MRI) technique has emerged as a front-line diagnostic tool for brain tumors without ionizing radiation. Manual segmentation of brain tumor extent from 3D MRI volumes is a very time-consuming task and the performance is highly relied on operator's experience. In this context, a reliable fully automatic segmentation method for the brain tumor segmentation is necessary for an efficient measurement of the tumor extent. In this study, we p…
Indian Institute of Technology, Madras（马德拉斯印度理工学院）
In this paper we propose a fully automatic 2-stage cascaded approach for segmentation of liver and its tumors in CT (Computed Tomography) images using densely connected fully convolutional neural network (DenseNet). We independently train liver and tumor segmentation models and cascade them for a combined segmentation of the liver and its tumor. The first stage involves segmentation of liver and the second stage uses the first stage's segmentation results for localization of liver and henceforth tumor segmentations inside liver region. The liver model was trained on the down-sampled axial slic…
A cascade of fully convolutional neural networks is proposed to segment multi-modal Magnetic Resonance (MR) images with brain tumor into background and three hierarchical regions: whole tumor, tumor core and enhancing tumor core. The cascade is designed to decompose the multi-class segmentation problem into a sequence of three binary segmentation problems according to the subregion hierarchy. The whole tumor is segmented in the first step and the bounding box of the result is used for the tumor core segmentation in the second step. The enhancing tumor core is then segmented based on the boundi…
Automatic segmentation of liver and its tumors is an essential step for extracting quantitative imaging biomarkers for accurate tumor detection, diagnosis, prognosis and assessment of tumor response to treatment. MICCAI 2017 Liver Tumor Segmentation Challenge (LiTS) provides a common platform for comparing different automatic algorithms on contrast-enhanced abdominal CT images in tasks including 1) liver segmentation, 2) liver tumor segmentation, and 3) tumor burden estimation. We participate this challenge by developing a hierarchical framework based on deep fully convolutional-deconvolutiona…
In this work, we propose a multi-modal Convolutional Neural Network (CNN) approach for brain tumor segmentation. We investigate how to combine different modalities efficiently in the CNN framework.We adapt various fusion methods, which are previously employed on video recognition problem, to the brain tumor segmentation problem,and we investigate their efficiency in terms of memory and performance.Our experiments, which are performed on BRATS dataset, lead us to the conclusion that learning separate representations for each modality and combining them for brain tumor segmentation could increas…
University of Calcutta（加尔各答大学）；West Bengal University of Technology（西孟加拉技术大学）
Tumor segmentation from magnetic resonance imaging (MRI) data is an important but time consuming manual task performed by medical experts. Automating this process is a challenging task because of the high diversity in the appearance of tumor tissues among different patients and in many cases similarity with the normal tissues. MRI is an advanced medical imaging technique providing rich information about the human soft-tissue anatomy. There are different brain tumor detection and segmentation methods to detect and segment a brain tumor from MRI images. These detection and segmentation approache…
Department of Neuro-Oncology, Massachusetts General Hospital（麻省总医院神经肿瘤科）；MGH & BWH Center for Clinical Data Science（麻省总医院与布莱根妇女医院临床数据科学中心）；Department of Radiology, Massachusetts General Hospital（麻省总医院放射科）；Massachusetts General Hospital（麻省总医院）；NVIDIA（英伟达）
Deep learning has quickly become the weapon of choice for brain lesion segmentation. However, few existing algorithms pre-configure any biological context of their chosen segmentation tissues, and instead rely on the neural network's optimizer to develop such associations de novo. We present a novel method for applying deep neural networks to the problem of glioma tissue segmentation that takes into account the structured nature of gliomas - edematous tissue surrounding mutually-exclusive regions of enhancing and non-enhancing tumor. We trained multiple deep neural networks with a 3D U-Net arc…
University of California, Los Angeles（加利福尼亚大学洛杉矶分校）；Institute of Computing Technology, Chinese Academy of Sciences（中国科学院计算技术研究所）；University of Chinese Academy of Sciences（中国科学院大学）；Lenovo Corporate Research & Development, Lenovo Ltd.（联想有限公司联想企业研究院）
Deep learning models are notoriously data-hungry. Thus, there is an urging need for data-efficient techniques in medical image analysis, where well-annotated data are costly and time consuming to collect. Motivated by the recently revived "Copy-Paste" augmentation, we propose TumorCP, a simple but effective object-level data augmentation method tailored for tumor segmentation. TumorCP is online and stochastic, providing unlimited augmentation possibilities for tumors' subjects, locations, appearances, as well as morphologies. Experiments on kidney tumor segmentation task demonstrate that Tumor…
Yokohama City University Medical Center（横滨市立大学医学中心）
We present a fully automatic method employing convolutional neural networks based on the 2D U-net architecture and random forest classifier to solve the automatic liver lesion segmentation problem of the ISBI 2017 Liver Tumor Segmentation Challenge (LiTS). In order to constrain the ROI in which the tumors could be located, a liver segmentation is performed first. For the organ segmentation, an ensemble of convolutional networks is trained to segment a liver using a set of 179 liver CT datasets from liver surgery planning. Inside of the liver ROI a neural network, trained using 127 challenge tr…
School of Computer Science, University of Lincoln（林肯大学计算机科学学院）；National Heart & Lung Institute, Imperial College London（帝国理工学院国家心肺研究所）
In this paper, we propose a novel learning based method for automated segmentation of brain tumor in multimodal MRI images, which incorporates two sets of machine -learned and hand crafted features. Fully convolutional networks (FCN) forms the machine learned features and texton based features are considered as hand-crafted features. Random forest (RF) is used to classify the MRI image voxels into normal brain tissues and different parts of tumors, i.e. edema, necrosis and enhancing tumor. The method was evaluated on BRATS 2017 challenge dataset. The results show that the proposed method provi…
National Institutes of Health Clinical Center（美国国立卫生研究院临床中心）
This paper reports Deep LOGISMOS approach to 3D tumor segmentation by incorporating boundary information derived from deep contextual learning to LOGISMOS - layered optimal graph image segmentation of multiple objects and surfaces. Accurate and reliable tumor segmentation is essential to tumor growth analysis and treatment selection. A fully convolutional network (FCN), UNet, is first trained using three adjacent 2D patches centered at the tumor, providing contextual UNet segmentation and probability map for each 2D patch. The UNet segmentation is then refined by Gaussian Mixture Model (GMM) a…
King’s College London（伦敦国王学院）；University College London（伦敦大学学院）
Automatic brain tumor segmentation plays an important role for diagnosis, surgical planning and treatment assessment of brain tumors. Deep convolutional neural networks (CNNs) have been widely used for this task. Due to the relatively small data set for training, data augmentation at training time has been commonly used for better performance of CNNs. Recent works also demonstrated the usefulness of using augmentation at test time, in addition to training time, for achieving more robust predictions. We investigate how test-time augmentation can improve CNNs' performance for brain tumor segment…
Automatic image segmentation becomes very crucial for tumor detection in medical image processing.In general, manual and semi automatic segmentation techniques require more time and knowledge. However these drawbacks had overcome by automatic segmentation still there needs to develop more appropriate techniques for medical image segmentation. Therefore, we proposed hybrid approach based image segmentation using the combined features of region growing and threshold based segmentation techniques. It is followed by pre-processing stage to provide an accurate brain tumor extraction by the help of …
Magnetic Resonance Imaging (MRI) is an important diagnostic tool for precise detection of various pathologies. Magnetic Resonance (MR) is more preferred than Computed Tomography (CT) due to the high resolution in MR images which help in better detection of neurological conditions. Graphical user interface (GUI) aided disease detection has become increasingly useful due to the increasing workload of doctors. In this proposed work, a novel two steps GUI technique for brain tumor segmentation as well as Brodmann area detec-tion of the segmented tumor is proposed. A data set of T2 weighted images …
Five different threshold segmentation based approaches have been reviewed and compared over here to extract the tumor from set of brain images. This research focuses on the analysis of image segmentation methods, a comparison of five semi-automated methods have been undertaken for evaluating their relative performance in the segmentation of tumor. Consequently, results are compared on the basis of quantitative and qualitative analysis of respective methods. The purpose of this study was to analytically identify the methods, most suitable for application for a particular genre of problems. The …
UPMAD-Net: A Brain Tumor Segmentation Network with Uncertainty Guidance and Adaptive Multimodal Feature Fusion
School of Computer Science and Technology, Zhengzhou University of Light Industry（郑州轻工业大学计算机与通信工程学院）；Kennesaw State University（肯尼索州立大学）；Michigan Technological University（密歇根理工大学）
German Cancer Research Center (DKFZ)（德国癌症研究中心（DKFZ））；Heidelberg University Hospital（海德堡大学医院）
Quantitative analysis of brain tumors is critical for clinical decision making. While manual segmentation is tedious, time consuming and subjective, this task is at the same time very challenging to solve for automatic segmentation methods. In this paper we present our most recent effort on developing a robust segmentation algorithm in the form of a convolutional neural network. Our network architecture was inspired by the popular U-Net and has been carefully modified to maximize brain tumor segmentation performance. We use a dice loss function to cope with class imbalances and use extensive d…
University at Buffalo, The State University of New York（纽约州立大学布法罗分校）
Brain Tumor Segmentation from magnetic resonance imaging (MRI) is a critical technique for early diagnosis. However, rather than having complete four modalities as in BraTS dataset, it is common to have missing modalities in clinical scenarios. We design a brain tumor segmentation algorithm that is robust to the absence of any modality. Our network includes a channel-independent encoding path and a feature-fusion decoding path. We use self-supervised training through channel dropout and also propose a novel domain adaptation method on feature maps to recover the information from the missing ch…
Beijing-Dublin International College（北京-都柏林国际学院）；University College Dublin（都柏林大学）
This technical report presents a comparative analysis of existing deep learning (DL) based approaches for brain tumor segmentation with missing MRI modalities. Approaches evaluated include the Adversarial Co-training Network (ACN) and a combination of mmGAN and DeepMedic. A more stable and easy-to-use version of mmGAN is also open-sourced at a GitHub repository. Using the BraTS2018 dataset, this work demonstrates that the state-of-the-art ACN performs better especially when T1c is missing. While a simple combination of mmGAN and DeepMedic also shows strong potentials when only one MRI modality…
Shanghai Jiao Tong University（上海交通大学）；Shanghai AI Laboratory（上海人工智能实验室）
Automatic and accurate tumor segmentation on medical images is in high demand to assist physicians with diagnosis and treatment. However, it is difficult to obtain massive amounts of annotated training data required by the deep-learning models as the manual delineation process is often tedious and expertise required. Although self-supervised learning (SSL) scheme has been widely adopted to address this problem, most SSL methods focus only on global structure information, ignoring the key distinguishing features of tumor regions: local intensity variation and large size distribution. In this pa…
The brain tumor segmentation on MRI images is a very difficult and important task which is used in surgical and medical planning and assessments. If experts do the segmentation manually with their own medical knowledge, it will be time-consuming. Therefore, researchers propose methods and systems which can do the segmentation automatically and without any interference. In this article, an unsupervised automatic method for brain tumor segmentation on MRI images is presented. In this method, at first in the pre-processing level, the extra parts which are outside the skull and don't have any help…
We explore encoding brain symmetry into a neural network for a brain tumor segmentation task. A healthy human brain is symmetric at a high level of abstraction, and the high-level asymmetric parts are more likely to be tumor regions. Paying more attention to asymmetries has the potential to boost the performance in brain tumor segmentation. We propose a method to encode brain symmetry into existing neural networks and apply the method to a state-of-the-art neural network for medical imaging segmentation. We evaluate our symmetry-encoded network on the dataset from a brain tumor segmentation ch…
Hasso Plattner Institute for Digital Engineering（哈索·普拉特纳数字工程研究院）
Automated medical image analysis has a significant value in diagnosis and treatment of lesions. Brain tumors segmentation has a special importance and difficulty due to the difference in appearances and shapes of the different tumor regions in magnetic resonance images. Additionally, the data sets are heterogeneous and usually limited in size in comparison with the computer vision problems. The recently proposed adversarial training has shown promising results in generative image modeling. In this paper, we propose a novel end-to-end trainable architecture for brain tumor semantic segmentation…
University of Minho（米尼奥大学）；CMEMS-UMinho Research Unit, University of Minho（米尼奥大学CMEMS-UMinho研究中心）；Centro Algoritmi, University of Minho（米尼奥大学阿尔戈里蒂米中心）
Convolutional neural networks (CNNs) have been successfully used for brain tumor segmentation, specifically, fully convolutional networks (FCNs). FCNs can segment a set of voxels at once, having a direct spatial correspondence between units in feature maps (FMs) at a given location and the corresponding classified voxels. In convolutional layers, FMs are merged to create new FMs, so, channel combination is crucial. However, not all FMs have the same relevance for a given class. Recently, in classification problems, Squeeze-and-Excitation (SE) blocks have been proposed to re-calibrate FMs as a …
RT-Super: Learning Tumor Segmentation from Longitudinal Images and Reports
Johns Hopkins University（约翰霍普金斯大学）；Harvard Medical School（哈佛医学院）；Massachusetts General Hospital（马萨诸塞总医院）；University of California, San Francisco（加利福尼亚大学旧金山分校）；University of Zurich（苏黎世大学）；Istanbul Medipol University（伊斯坦布尔梅迪波尔大学）；Johns Hopkins Medicine（约翰霍普金斯医学）
In this paper, we propose sparse coding-based approaches for segmentation of tumor regions from MR images. Sparse coding with data-adapted dictionaries has been successfully employed in several image recovery and vision problems. The proposed approaches obtain sparse codes for each pixel in brain magnetic resonance images considering their intensity values and location information. Since it is trivial to obtain pixel-wise sparse codes, and combining multiple features in the sparse coding setup is not straightforward, we propose to perform sparse coding in a high-dimensional feature space where…
Segmentation of images holds an important position in the area of image processing. It becomes more important whi le typically dealing with medical images where presurgery and post surgery decisions are required for the purpose of initiating and speeding up the recovery process. Segmentation of 3-D tumor structures from magnetic resonance images (MRI) is a very challenging problem due to the variability of tumor geometry and intensity patterns. Level set evolution combining global smoothness with the flexibility of topology changes offers significant advantages over the conventional statistica…
The Chinese University of Hong Kong（香港中文大学）；Imsight Medical Technology, Inc.（伊赛智能医疗科技有限公司）
Liver cancer is one of the leading causes of cancer death. To assist doctors in hepatocellular carcinoma diagnosis and treatment planning, an accurate and automatic liver and tumor segmentation method is highly demanded in the clinical practice. Recently, fully convolutional neural networks (FCNs), including 2D and 3D FCNs, serve as the back-bone in many volumetric image segmentation. However, 2D convolutions can not fully leverage the spatial information along the third dimension while 3D convolutions suffer from high computational cost and GPU memory consumption. To address these issues, we …
MAST-Pro: Dynamic Mixture-of-Experts for Adaptive Segmentation of Pan-Tumors with Knowledge-Driven Prompts
State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University（上海科技大学先进医用材料与器件国家重点实验室）；Center of Advanced Medical Computing and Analysis, Massachusetts General Hospital（麻省总医院高级医学计算与分析中心）；Harvard Medical School, Harvard University（哈佛大学医学院）；Shanghai United Imaging Intelligence Co., Ltd.（上海联影智能医疗科技有限公司）；Shanghai Clinical Research and Trial Center（上海临床研究与试验中心）
South China University of Technology（华南理工大学）；Rochester Institute of Technology（罗切斯特理工学院）
Due to the difficulties of obtaining multimodal paired images in clinical practice, recent studies propose to train brain tumor segmentation models with unpaired images and capture complementary information through modality translation. However, these models cannot fully exploit the complementary information from different modalities. In this work, we thus present a novel two-step (intra-modality and inter-modality) curriculum disentanglement learning framework to effectively utilize privileged semi-paired images, i.e. limited paired images that are only available in training, for brain tumor …
Image segmentation some of the challenging issues on brain magnetic resonance image tumor segmentation caused by the weak correlation between magnetic resonance imaging intensity and anatomical meaning.With the objective of utilizing more meaningful information to improve brain tumor segmentation,an approach which employs bilateral symmetry information as an additional feature for segmentation is proposed.This is motivated by potential performance improvement in the general automatic brain tumor segmentation systems which are important for many medical and scientific applications.Brain Magneti…
Non-invasive techniques such as magnetic resonance imaging (MRI) are widely employed in brain tumor diagnostics. However, manual segmentation of brain tumors from 3D MRI volumes is a time-consuming task that requires trained expert radiologists. Due to the subjectivity of manual segmentation, there is low inter-rater reliability which can result in diagnostic discrepancies. As the success of many brain tumor treatments depends on early intervention, early detection is paramount. In this context, a fully automated segmentation method for brain tumor segmentation is necessary as an efficient and…
This article presents a multiscale patch based convolutional neural network for the automatic segmentation of brain tumors in multi-modality 3D MR images. We use multiscale deep supervision and inputs to train a convolutional network. We evaluate the effectiveness of the proposed approach on the BRATS 2017 segmentation challenge where we obtained dice scores of 0.755, 0.900, 0.782 and 95% Hausdorff distance of 3.63mm, 4.10mm, and 6.81mm for enhanced tumor core, whole tumor and tumor core respectively.
Vingroup Big Data Institute (VinBigdata)（越南 VinBigdata 大数据研究院）；Hanoi University of Science and Technology (HUST)（河内科技大学）；University of Engineering and Technology (UET), VNU（越南国立大学工程技术大学）
Brain tumor segmentation plays an essential role in medical image analysis. In recent studies, deep convolution neural networks (DCNNs) are extremely powerful to tackle tumor segmentation tasks. We propose in this paper a novel training method that enhances the segmentation results by adding an additional classification branch to the network. The whole network was trained end-to-end on the Multimodal Brain Tumor Segmentation Challenge (BraTS) 2020 training dataset. On the BraTS's validation set, it achieved an average Dice score of 78.43%, 89.99%, and 84.22% respectively for the enhancing tumo…
Research & Development Institute of Northwestern Polytechnical University in Shenzhen（西北工业大学深圳研究院）；Northwestern Polytechnical University（西北工业大学）；University of Pittsburgh（匹兹堡大学）；University of Sydney（悉尼大学）；JD Finance America Corporation（京东金融美国公司）
In this paper, we propose a Hybrid High-resolution and Non-local Feature Network (H2NF-Net) to segment brain tumor in multimodal MR images. Our H2NF-Net uses the single and cascaded HNF-Nets to segment different brain tumor sub-regions and combines the predictions together as the final segmentation. We trained and evaluated our model on the Multimodal Brain Tumor Segmentation Challenge (BraTS) 2020 dataset. The results on the test set show that the combination of the single and cascaded models achieved average Dice scores of 0.78751, 0.91290, and 0.85461, as well as Hausdorff distances ($95\%$…
In the past few years, deep learning (DL) models have drawn great attention and shown superior performance on brain tumor and subregion segmentation tasks. However, the success is limited to segmentation of adult gliomas, where sufficient data have been collected, manually labeled, and published for training DL models. It is still challenging to segment pediatric tumors, because the appearances are different from adult gliomas. Hence, directly applying a pretained DL model on pediatric data usually generates unacceptable results. Because pediatric data is very limited, both labeled and unlabel…
School of Biomedical Engineering（生物医学工程学院）；Universidad Autónoma de Ciudad Juárez（华雷斯自治大学）
The brain is a complex organ controlling cognitive process and physical functions. Tumors in the brain are accelerated cell growths affecting the normal function and processes in the brain. MRI scans provides detailed images of the body being one of the most common tests to diagnose brain tumors. The process of segmentation of brain tumors from magnetic resonance imaging can provide a valuable guide for diagnosis, treatment planning and prediction of results. Here we consider the problem brain tumor segmentation using a Deep learning architecture for use in tumor segmentation. Although the pro…
Shenzhen University（深圳大学）；Huazhong University of Science and Technology（华中科技大学）
The brain tumor segmentation task aims to classify tissue into the whole tumor (WT), tumor core (TC), and enhancing tumor (ET) classes using multimodel MRI images. Quantitative analysis of brain tumors is critical for clinical decision making. While manual segmentation is tedious, time-consuming, and subjective, this task is at the same time very challenging to automatic segmentation methods. Thanks to the powerful learning ability, convolutional neural networks (CNNs), mainly fully convolutional networks, have shown promising brain tumor segmentation. This paper further boosts the performance…
Rowan University（罗文大学）；University of Alabama at Birmingham（阿拉巴马大学伯明翰分校）
Magnetic resonance imaging (MRI) is routinely used for brain tumor diagnosis, treatment planning, and post-treatment surveillance. Recently, various models based on deep neural networks have been proposed for the pixel-level segmentation of tumors in brain MRIs. However, the structural variations, spatial dissimilarities, and intensity inhomogeneity in MRIs make segmentation a challenging task. We propose a new end-to-end brain tumor segmentation architecture based on U-Net that integrates Inception modules and dilated convolutions into its contracting and expanding paths. This allows us to ex…
University of Leicester（莱斯特大学）；University of Lancaster（兰卡斯特大学）；Queen Mary, University of London（伦敦大学玛丽女王学院）；Xidian University（西安电子科技大学）；Bielefeld University（比勒费尔德大学）
Brain tumor segmentation is one of the most challenging problems in medical image analysis. The goal of brain tumor segmentation is to generate accurate delineation of brain tumor regions. In recent years, deep learning methods have shown promising performance in solving various computer vision problems, such as image classification, object detection and semantic segmentation. A number of deep learning based methods have been applied to brain tumor segmentation and achieved promising results. Considering the remarkable breakthroughs made by state-of-the-art technologies, we use this survey to …
Georgia Institute of Technology（佐治亚理工学院）；Telecom Paris（巴黎电信学院）；Medicine School of Tunis（突尼斯医学院）
Breast cancer is one of the factors that cause the increase of mortality of women. The most widely used method for diagnosing this geological disease i.e. breast cancer is the ultrasound scan. Several key features such as the smoothness and the texture of the tumor captured through ultrasound scans encode the abnormality of the breast tumors (malignant from benign). However, ultrasound scans are often noisy and include irrelevant parts of the breast that may bias the segmentation of eventual tumors. In this paper, we are going to extract the region of interest ( i.e, bounding boxes of the tumo…
Northwestern University（西北大学）；University of Chicago（芝加哥大学）
Head and Neck (H\&N) organ-at-risk (OAR) and tumor segmentations are essential components of radiation therapy planning. The varying anatomic locations and dimensions of H\&N nodal Gross Tumor Volumes (GTVn) and H\&N primary gross tumor volume (GTVp) are difficult to obtain due to lack of accurate and reliable delineation methods. The downstream effect of incorrect segmentation can result in unnecessary irradiation of normal organs. Towards a fully automated radiation therapy planning algorithm, we explore the efficacy of multi-scale fusion based deep learning architectures for accurately segm…
Brain Tumor Segmentation with Special Emphasis on the Non-Enhancing Brain Tumor Compartment
CIML Group, Biophysics, University of Regensburg（里堡大学生物物理组）；Department of Neurosurgery , University Hospital Regensburg（里堡大学神经外科部门）；Department of Biomedical Imaging, University Hospital Regensburg（里堡大学生物医学成像部门）；DETI, IEETA, Universidade de Aveiro（阿维罗大学DETI和IEETA）
Kavli Institute for Systems Neuroscience, NTNU（挪威科技大学卡弗里系统神经科学研究所）
Early diagnosis and accurate segmentation of brain tumors are imperative for successful treatment. Unfortunately, manual segmentation is time consuming, costly and despite extensive human expertise often inaccurate. Here, we present an MRI-based tumor segmentation framework using an autoencoder-regularized 3D-convolutional neural network. We trained the model on manually segmented structural T1, T1ce, T2, and Flair MRI images of 335 patients with tumors of variable severity, size and location. We then tested the model using independent data of 125 patients and successfully segmented brain tumo…
