Direct Cardiac Segmentation from Undersampled K-space Using Transformers
School of Computation, Information and Technology, Technical University Munich（计算、信息与技术学院，技术大学慕尼黑）；Klinikum Rechts der Isar, Technical University Munich（技术大学慕尼黑医院）；Munich Center for Machine Learning, Technical University Munich（慕尼黑机器学习中心，技术大学慕尼黑）；Department of Computing, Imperial College London（计算系，帝国理工学院伦敦）
The prevailing deep learning-based methods of predicting cardiac segmentation involve reconstructed magnetic resonance (MR) images. The heavy dependency of segmentation approaches on image quality significantly limits the acceleration rate in fast MR reconstruction. Moreover, the practice of treating reconstruction and segmentation as separate sequential processes leads to artifact generation and information loss in the intermediate stage. These issues pose a great risk to achieving high-quality outcomes. To leverage the redundant k-space information overlooked in this dual-step pipeline, we introduce a novel approach to directly deriving segmentations from sparse k-space samples using a transformer (DiSK). DiSK operates by globally extracting latent features from 2D+time k-space data with attention blocks and subsequently predicting the segmentation label of query points. We evaluate our model under various acceleration factors (ranging from 4 to 64) and compare against two image-based segmentation baselines. Our model consistently outperforms the baselines in Dice and Hausdorff distances across foreground classes for all presented sampling rates.
Cine cardiac magnetic resonance (CMR) imaging is considered the gold standard for cardiac function evaluation. However, cine CMR acquisition is inherently slow and in recent decades considerable effort has been put into accelerating scan times without compromising image quality or the accuracy of derived results. In this paper, we present a fully-automated, quality-controlled integrated framework for reconstruction, segmentation and downstream analysis of undersampled cine CMR data. The framework enables active acquisition of radial k-space data, in which acquisition can be stopped as soon as …
Department of Computing, Imperial College London, London, UK（英国伦敦帝国理工学院计算机系）；Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK（英国牛津大学拉德克利夫医学院心血管医学系）；NIHR Biomedical Research Centre at Barts, Queen Mary University of London, London, UK（英国伦敦玛丽女王大学巴茨国家健康研究所）
Accelerating the acquisition of magnetic resonance imaging (MRI) is a challenging problem, and many works have been proposed to reconstruct images from undersampled k-space data. However, if the main purpose is to extract certain quantitative measures from the images, perfect reconstructions may not always be necessary as long as the images enable the means of extracting the clinically relevant measures. In this paper, we work on jointly predicting cardiac motion estimation and segmentation directly from undersampled data, which are two important steps in quantitatively assessing cardiac funct…
School of Biomedical Engineering & Imaging Sciences, King’s College London, UK（伦敦国王学院生物医学工程与成像科学学院）；Technical University of Munich, Germany（慕尼黑工业大学）；Biomedical Image Analysis Group, Imperial College London, UK（帝国理工学院生物医学图像分析组）；Department of Adult and Paediatric Cardiology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK（盖伊和圣托马斯国民健康服务信托基金会成人及儿科心脏病科）；Coimbra Institute for Biomedical Imaging and Translational Research, University of Coimbra, Portugal（科英布拉大学科英布拉生物医学成像与转化研究学院）；Helmholtz Center Munich, Germany（慕尼黑亥姆霍兹中心）
Cine cardiac MRI is routinely acquired for the assessment of cardiac health, but the imaging process is slow and typically requires several breath-holds to acquire sufficient k-space profiles to ensure good image quality. Several undersampling-based reconstruction techniques have been proposed during the last decades to speed up cine cardiac MRI acquisition. However, the undersampling factor is commonly fixed to conservative values before acquisition to ensure diagnostic image quality, potentially leading to unnecessarily long scan times. In this paper, we propose an end-to-end quality-aware c…
The Challenge of Fetal Cardiac MRI Reconstruction Using Deep Learning
King’s College London（伦敦国王学院）；Technical University of Munich（慕尼黑工业大学）；Imperial College London（帝国理工学院）；Guy’s & St. Thomas’ NHS Foundation Trust（盖伊和圣托马斯国民保健服务基金会信托）；Evelina London Children’s Hospital（伊夫琳娜伦敦儿童医院）
Real-time cardiac cine MRI -- A comparison of a diffusion probabilistic model with alternative state-of-the-art image reconstruction techniques for undersampled spiral acquisitions
United Imaging Intelligence（联影智能）；UIH America, Inc.（联影美国公司）；United Imaging Healthcare（联影医疗）
Retrospectively gated cine (retro-cine) MRI is the clinical standard for cardiac functional analysis. Deep learning (DL) based methods have been proposed for the reconstruction of highly undersampled MRI data and show superior image quality and magnitude faster reconstruction time than CS-based methods. Nevertheless, it remains unclear whether DL reconstruction is suitable for cardiac function analysis. To address this question, in this study we evaluate and compare the cardiac functional values (EDV, ESV and EF for LV and RV, respectively) obtained from highly accelerated MRI acquisition usin…
Rutgers University（罗格斯大学）；SenseBrain Research（SenseBrain研究院）；University of Arkansas for Medical Sciences（阿肯色大学医学院）；Lund University（隆德大学）；New York University（纽约大学）
Joint 2D cardiac segmentation and 3D volume reconstruction are fundamental to building statistical cardiac anatomy models and understanding functional mechanisms from motion patterns. However, due to the low through-plane resolution of cine MR and high inter-subject variance, accurately segmenting cardiac images and reconstructing the 3D volume are challenging. In this study, we propose an end-to-end latent-space-based framework, DeepRecon, that generates multiple clinically essential outcomes, including accurate image segmentation, synthetic high-resolution 3D image, and 3D reconstructed volu…
Automated segmentation of human cardiac magnetic resonance datasets has been steadily improving during recent years. However, these methods are not directly applicable in preclinical context due to limited datasets and lower image resolution. Successful application of deep architectures for rat cardiac segmentation, although of critical importance for preclinical evaluation of cardiac function, has to our knowledge not yet been reported. We developed segmentation models that expand on the standard U-Net architecture and evaluated separate models for systole and diastole phases, 2MSA, and one m…
University of Notre Dame（圣母大学）；Guangdong Cardiovascular Institute（广东省心血管病研究所）；Guangdong Provincial People’s Hospital（广东省人民医院）；Boston Children’s Hospital（波士顿儿童医院）；Harvard Medical School（哈佛医学院）；University of Pittsburgh（匹兹堡大学）
Real-time cardiac magnetic resonance imaging (MRI) plays an increasingly important role in guiding various cardiac interventions. In order to provide better visual assistance, the cine MRI frames need to be segmented on-the-fly to avoid noticeable visual lag. In addition, considering reliability and patient data privacy, the computation is preferably done on local hardware. State-of-the-art MRI segmentation methods mostly focus on accuracy only, and can hardly be adopted for real-time application or on local hardware. In this work, we present the first hardware-aware multi-scale neural archite…
In recent years, convolutional neural networks have demonstrated promising performance in a variety of medical image segmentation tasks. However, when a trained segmentation model is deployed into the real clinical world, the model may not perform optimally. A major challenge is the potential poor-quality segmentations generated due to degraded image quality or domain shift issues. There is a timely need to develop an automated quality control method that can detect poor segmentations and feedback to clinicians. Here we propose a novel deep generative model-based framework for quality control …
United Imaging Intelligence（联影智能）；UIH America, Inc.（联影美国公司）
Real-time cardiac cine MRI does not require ECG gating in the data acquisition and is more useful for patients who can not hold their breaths or have abnormal heart rhythms. However, to achieve fast image acquisition, real-time cine commonly acquires highly undersampled data, which imposes a significant challenge for MRI image reconstruction. We propose a residual convolutional RNN for real-time cardiac cine reconstruction. To the best of our knowledge, this is the first work applying deep learning approach to Cartesian real-time cardiac cine reconstruction. Based on the evaluation from radiol…
University of Sherbrooke（舍布鲁克大学）；University of Bourgogne Franche-Comte（勃艮第-弗朗什孔泰大学）；CASIS inc.（CASIS公司）；University of Lyon（里昂大学）
Convolutional neural networks (CNN) have had unprecedented success in medical imaging and, in particular, in medical image segmentation. However, despite the fact that segmentation results are closer than ever to the inter-expert variability, CNNs are not immune to producing anatomically inaccurate segmentations, even when built upon a shape prior. In this paper, we present a framework for producing cardiac image segmentation maps that are guaranteed to respect pre-defined anatomical criteria, while remaining within the inter-expert variability. The idea behind our method is to use a well-trai…
Institute of Computing, Universidade Federal Fluminense (UFF)（弗鲁米嫩塞联邦大学计算研究所）；School of Medicine, Universidade Federal do Rio de Janeiro (UFRJ)（里约热内卢联邦大学医学院）
The quantification of fat depots on the surroundings of the heart is an accurate procedure for evaluating health risk factors correlated with several diseases. However, this type of evaluation is not widely employed in clinical practice due to the required human workload. This work proposes a novel technique for the automatic segmentation of cardiac fat pads. The technique is based on applying classification algorithms to the segmentation of cardiac CT images. Furthermore, we extensively evaluate the performance of several algorithms on this task and discuss which provided better predictive mo…
University of Bourgogne Franche-Comte（勃艮第-弗朗什-孔泰大学）；CASIS inc.（CASIS公司）；University of Sherbrooke（舍布鲁克大学）；University Hospital of Dijon（第戎大学医院）
Deep learning methods are the de-facto solutions to a multitude of medical image analysis tasks. Cardiac MRI segmentation is one such application which, like many others, requires a large number of annotated data so a trained network can generalize well. Unfortunately, the process of having a large number of manually curated images by medical experts is both slow and utterly expensive. In this paper, we set out to explore whether expert knowledge is a strict requirement for the creation of annotated datasets that machine learning can successfully train on. To do so, we gauged the performance o…
Medical image segmentation has significantly benefitted thanks to deep learning architectures. Furthermore, semi-supervised learning (SSL) has recently been a growing trend for improving a model's overall performance by leveraging abundant unlabeled data. Moreover, learning multiple tasks within the same model further improves model generalizability. To generate smoother and accurate segmentation masks from 3D cardiac MR images, we present a Multi-task Cross-task learning consistency approach to enforce the correlation between the pixel-level (segmentation) and the geometric-level (distance ma…
Klinikum Rechts der Isar, Technical University of Munich（慕尼黑工业大学伊萨尔河右岸医院）；Imperial College London（伦敦帝国理工学院）；University Hospital of Tübingen（图宾根大学医院）
Motion-compensated MR reconstruction (MCMR) is a powerful concept with considerable potential, consisting of two coupled sub-problems: Motion estimation, assuming a known image, and image reconstruction, assuming known motion. In this work, we propose a learning-based self-supervised framework for MCMR, to efficiently deal with non-rigid motion corruption in cardiac MR imaging. Contrary to conventional MCMR methods in which the motion is estimated prior to reconstruction and remains unchanged during the iterative optimization process, we introduce a dynamic motion estimation process and embed …
Deep Separable Spatiotemporal Learning for Fast Dynamic Cardiac MRI
Xiamen University（厦门大学）；Fudan University（复旦大学）；Xiamen Cardiovascular Hospital of Xiamen University（厦门大学附属厦门心血管病医院）；School of Medicine, Xiamen University（厦门大学医学院）；Ruijin Hospital Lu Wan Branch, Shanghai Jiaotong University School of Medicine（上海交通大学医学院附属瑞金医院卢湾分院）；Shanghai Institute of Cardiovascular Diseases（上海市心血管病研究所）；Zhongshan Hospital, Fudan University（复旦大学附属中山医院）；Shanghai Medical School, Fudan University（复旦大学上海医学院）；Shanghai Institute of Medical Imaging（上海市医学影像研究所）；Xiamen University of Technology（厦门理工学院）；Imperial College London（帝国理工学院）
Automatic and accurate segmentation of the ventricles and myocardium from multi-sequence cardiac MRI (CMR) is crucial for the diagnosis and treatment management for patients suffering from myocardial infarction (MI). However, due to the existence of domain shift among different modalities of datasets, the performance of deep neural networks drops significantly when the training and testing datasets are distinct. In this paper, we propose an unsupervised domain alignment method to explicitly alleviate the domain shifts among different modalities of CMR sequences, \emph{e.g.,} bSSFP, LGE, and T2…
Imperial College London（伦敦帝国学院）；City, University of London（伦敦城市大学）；University of Birmingham（伯明翰大学）
Deep learning has become the most widely used approach for cardiac image segmentation in recent years. In this paper, we provide a review of over 100 cardiac image segmentation papers using deep learning, which covers common imaging modalities including magnetic resonance imaging (MRI), computed tomography (CT), and ultrasound (US) and major anatomical structures of interest (ventricles, atria and vessels). In addition, a summary of publicly available cardiac image datasets and code repositories are included to provide a base for encouraging reproducible research. Finally, we discuss the chall…
University College London（伦敦大学学院）；Centre for Medical Image Computing（医学图像计算中心）
Accurate segmentation of the right ventricle (RV) is a crucial step in the assessment of the ventricular structure and function. Yet, due to its complex anatomy and motion segmentation of the RV has not been as largely studied as the left ventricle. This paper presents a fully automatic method for the segmentation of the RV in cardiac magnetic resonance images (MRI). The method uses a coarse-to-fine segmentation strategy in combination with a multi-atlas propagation segmentation framework. Based on a cross correlation metric, our method selects the best atlases for propagation allowing the ref…
Deep models often suffer from severe performance drop due to the appearance shift in the real clinical setting. Most of the existing learning-based methods rely on images from multiple sites/vendors or even corresponding labels. However, collecting enough unknown data to robustly model segmentation cannot always hold since the complex appearance shift caused by imaging factors in daily application. In this paper, we propose a novel style-invariant method for cardiac image segmentation. Based on the zero-shot style transfer to remove appearance shift and test-time augmentation to explore divers…
Amsterdam UMC, University of Amsterdam（阿姆斯特丹大学阿姆斯特丹大学医学中心）；Amsterdam University Medical Center, University of Amsterdam（阿姆斯特丹大学阿姆斯特丹大学医学中心）；University Medical Center Utrecht（乌得勒支大学医学中心）
Segmentation of cardiac anatomical structures in cardiac magnetic resonance images (CMRI) is a prerequisite for automatic diagnosis and prognosis of cardiovascular diseases. To increase robustness and performance of segmentation methods this study combines automatic segmentation and assessment of segmentation uncertainty in CMRI to detect image regions containing local segmentation failures. Three state-of-the-art convolutional neural networks (CNN) were trained to automatically segment cardiac anatomical structures and obtain two measures of predictive uncertainty: entropy and a measure deriv…
Imperial College London（帝国理工学院）；Queen Mary University of London（伦敦玛丽女王大学）
Cardiac MR image segmentation is essential for the morphological and functional analysis of the heart. Inspired by how experienced clinicians assess the cardiac morphology and function across multiple standard views (i.e. long- and short-axis views), we propose a novel approach which learns anatomical shape priors across different 2D standard views and leverages these priors to segment the left ventricular (LV) myocardium from short-axis MR image stacks. The proposed segmentation method has the advantage of being a 2D network but at the same time incorporates spatial context from multiple, com…
Biomedical Image Analysis Group, Imperial College London（伦敦帝国理工学院生物医学图像分析小组）；Data Science Institute, Imperial College London（伦敦帝国理工学院数据科学研究所）；Department of Medicine, Imperial College London（伦敦帝国理工学院医学院）
In this work, we present a fully automatic method to segment cardiac structures from late-gadolinium enhanced (LGE) images without using labelled LGE data for training, but instead by transferring the anatomical knowledge and features learned on annotated balanced steady-state free precession (bSSFP) images, which are easier to acquire. Our framework mainly consists of two neural networks: a multi-modal image translation network for style transfer and a cascaded segmentation network for image segmentation. The multi-modal image translation network generates realistic and diverse synthetic LGE …
Automatic diagnosis of cardiac magnetic resonance images based on semi-supervised learning
School of Information and Electrical Engineering, Hunan University of Science and Technology（湖南科技大学信息与电气工程学院）；Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）；Guilin Medical University（桂林医学院）；Rucheng County Hospital of Traditional Chinese Medicine（汝城县中医医院）
NVIDIA（英伟达）；MGH and BWH Center for Clinical Data Science（麻省总医院与布列根和妇女医院临床数据科学中心）
We propose a 4D convolutional neural network (CNN) for the segmentation of retrospective ECG-gated cardiac CT, a series of single-channel volumetric data over time. While only a small subset of volumes in the temporal sequence is annotated, we define a sparse loss function on available labels to allow the network to leverage unlabeled images during training and generate a fully segmented sequence. We investigate the accuracy of the proposed 4D network to predict temporally consistent segmentations and compare with traditional 3D segmentation approaches. We demonstrate the feasibility of the 4D…
With the advent of Cardiac Cine Magnetic Resonance (CMR) Imaging, there has been a paradigm shift in medical technology, thanks to its capability of imaging different structures within the heart without ionizing radiation. However, it is very challenging to conduct pre-operative planning of minimally invasive cardiac procedures without accurate segmentation and identification of the left ventricle (LV), right ventricle (RV) blood-pool, and LV-myocardium. Manual segmentation of those structures, nevertheless, is time-consuming and often prone to error and biased outcomes. Hence, automatic and c…
Towards Robust Cardiac Segmentation using Graph Convolutional Networks
Norwegian University of Science and Technology（挪威科技大学）；University of Oslo（奥斯陆大学）；GE Research（GE研究中心）；St. Olavs hospital（圣奥拉夫斯医院）；Levanger hospital（莱旺厄尔医院）；SINTEF Health（辛特福健康研究院）
Fudan University（复旦大学）；Imperial College London（帝国理工学院）；University of Edinburgh（爱丁堡大学）；MRC London Institute of Medical Sciences（英国医学研究委员会伦敦医学科学研究所）；National Heart Research Institute, Singapore（新加坡国家心脏研究所）
In cardiac magnetic resonance (CMR) imaging, a 3D high-resolution segmentation of the heart is essential for detailed description of its anatomical structures. However, due to the limit of acquisition duration and respiratory/cardiac motion, stacks of multi-slice 2D images are acquired in clinical routine. The segmentation of these images provides a low-resolution representation of cardiac anatomy, which may contain artefacts caused by motion. Here we propose a novel latent optimisation framework that jointly performs motion correction and super resolution for cardiac image segmentations. Give…
Columbia University（哥伦比亚大学）；Stevens Institute of Technology（史蒂文斯理工学院）；Imperial College London（帝国理工学院）；Institut Polytechnique de Paris（巴黎理工学院）
Automatically identifying the structural substrates underlying cardiac abnormalities can potentially provide real-time guidance for interventional procedures. With the knowledge of cardiac tissue substrates, the treatment of complex arrhythmias such as atrial fibrillation and ventricular tachycardia can be further optimized by detecting arrhythmia substrates to target for treatment (i.e., adipose) and identifying critical structures to avoid. Optical coherence tomography (OCT) is a real-time imaging modality that aids in addressing this need. Existing approaches for cardiac image analysis main…
Istanbul Technical University（伊斯坦布尔理工大学）；King’s College London（伦敦国王学院）
Segmenting anatomical structures in medical images has been successfully addressed with deep learning methods for a range of applications. However, this success is heavily dependent on the quality of the image that is being segmented. A commonly neglected point in the medical image analysis community is the vast amount of clinical images that have severe image artefacts due to organ motion, movement of the patient and/or image acquisition related issues. In this paper, we discuss the implications of image motion artefacts on cardiac MR segmentation and compare a variety of approaches for joint…
Automatic segmentation of myocardial contours and relevant areas like infraction and no-reflow is an important step for the quantitative evaluation of myocardial infarction. In this work, we propose a cascaded convolutional neural network for automatic myocardial infarction segmentation from delayed-enhancement cardiac MRI. We first use a 2D U-Net to focus on the intra-slice information to perform a preliminary segmentation. After that, we use a 3D U-Net to utilize the volumetric spatial information for a subtle segmentation. Our method is evaluated on the MICCAI 2020 EMIDEC challenge dataset …
Technical University of Munich（慕尼黑工业大学）；Southern University of Science and Technology（南方科技大学）
Tackling domain shifts in multi-centre and multi-vendor data sets remains challenging for cardiac image segmentation. In this paper, we propose a generalisable segmentation framework for cardiac image segmentation in which multi-centre, multi-vendor, multi-disease datasets are involved. A generative adversarial networks with an attention loss was proposed to translate the images from existing source domains to a target domain, thus to generate good-quality synthetic cardiac structure and enlarge the training set. A stack of data augmentation techniques was further used to simulate real-world t…
University of Sherbrooke（舍布鲁克大学）；Université de Bourgogne Franche-Comté（勃艮第-弗朗什孔泰大学）；CArdiac Simulation & Imaging Software（心脏模拟与成像软件公司）；Université de Lyon（里昂大学）
Recent publications have shown that the segmentation accuracy of modern-day convolutional neural networks (CNN) applied on cardiac MRI can reach the inter-expert variability, a great achievement in this area of research. However, despite these successes, CNNs still produce anatomically inaccurate segmentations as they provide no guarantee on the anatomical plausibility of their outcome, even when using a shape prior. In this paper, we propose a cardiac MRI segmentation method which always produces anatomically plausible results. At the core of the method is an adversarial variational autoencod…
National Heart and Lung Institute, Imperial College London（帝国理工学院国家心肺研究所）；Imperial College London（帝国理工学院）；Royal Brompton Hospital（皇家布朗普顿医院）
Temporal patterns of cardiac motion provide important information for cardiac disease diagnosis. This pattern could be obtained by three-directional CINE multi-slice left ventricular myocardial velocity mapping (3Dir MVM), which is a cardiac MR technique providing magnitude and phase information of the myocardial motion simultaneously. However, long acquisition time limits the usage of this technique by causing breathing artifacts, while shortening the time causes low temporal resolution and may provide an inaccurate assessment of cardiac motion. In this study, we proposed a frame synthesis al…
Compositional Segmentation of Cardiac Images Leveraging Metadata
School of Electronic Engineering and Computer Science, Queen Mary University of London（伦敦玛丽女王大学电子工程与计算机科学学院）；Queen Mary’s Digital Environment Research Institute (DERI)（玛丽女王数字环境研究所）；Department of Computer Science, University College London（伦敦大学学院计算机科学系）；School of Engineering and Materials Science, Queen Mary University of London（伦敦玛丽女王大学工程与材料科学学院）
Massachusetts General Hospital（麻省总医院）；Harvard Medical School（哈佛医学院）；National Taiwan University（台湾大学）；University of Southern California（南加州大学）
Assessment of cardiovascular disease (CVD) with cine magnetic resonance imaging (MRI) has been used to non-invasively evaluate detailed cardiac structure and function. Accurate segmentation of cardiac structures from cine MRI is a crucial step for early diagnosis and prognosis of CVD, and has been greatly improved with convolutional neural networks (CNN). There, however, are a number of limitations identified in CNN models, such as limited interpretability and high complexity, thus limiting their use in clinical practice. In this work, to address the limitations, we propose a lightweight and i…
Fudan University（复旦大学）；University of Oxford（牛津大学）；Chung-Ang University（中央大学）
Cardiac segmentation is in great demand for clinical practice. Due to the enormous labor of manual delineation, unsupervised segmentation is desired. The ill-posed optimization problem of this task is inherently challenging, requiring well-designed constraints. In this work, we propose an unsupervised framework for multi-class segmentation with both intensity and shape constraints. Firstly, we extend a conventional non-convex energy function as an intensity constraint and implement it with U-Net. For shape constraint, synthetic images are generated from anatomical labels via image-to-image tra…
Zhejiang University（浙江大学）；University of Notre Dame（圣母大学）
Automatic segmentation of cardiac magnetic resonance imaging (MRI) facilitates efficient and accurate volume measurement in clinical applications. However, due to anisotropic resolution and ambiguous border (e.g., right ventricular endocardium), existing methods suffer from the degradation of accuracy and robustness in 3D cardiac MRI video segmentation. In this paper, we propose a novel Deformable U-Net (DeU-Net) to fully exploit spatio-temporal information from 3D cardiac MRI video, including a Temporal Deformable Aggregation Module (TDAM) and a Deformable Global Position Attention (DGPA) net…
In nuclear imaging, limited resolution causes partial volume effects (PVEs) that affect image sharpness and quantitative accuracy. Partial volume correction (PVC) methods incorporating high-resolution anatomical information from CT or MRI have been demonstrated to be effective. However, such anatomical-guided methods typically require tedious image registration and segmentation steps. Accurately segmented organ templates are also hard to obtain, particularly in cardiac SPECT imaging, due to the lack of hybrid SPECT/CT scanners with high-end CT and associated motion artifacts. Slight mis-regist…
Université de Bourgogne Franche-Comté（勃艮第-弗朗什-孔泰大学）；Cardiac Simulation & Imaging Software（心脏模拟与成像软件公司）；University of Sherbrooke（舍布鲁克大学）；University Hospital of Dijon（第戎大学医院）
In this work, we propose a Variational Autoencoder (VAE) - Generative Adversarial Networks (GAN) model that can produce highly realistic MRI together with its pixel accurate groundtruth for the application of cine-MR image cardiac segmentation. On one side of our model is a Variational Autoencoder (VAE) trained to learn the latent representations of cardiac shapes. On the other side is a GAN that uses "SPatially-Adaptive (DE)Normalization" (SPADE) modules to generate realistic MR images tailored to a given anatomical map. At test time, the sampling of the VAE latent space allows to generate an…
School of Engineering, University of Edinburgh（爱丁堡大学工程学院）；Canon Medical Research Europe Ltd.（佳能医疗欧洲研究有限公司）；The Alan Turing Institute（艾伦·图灵研究所）
Robust cardiac image segmentation is still an open challenge due to the inability of the existing methods to achieve satisfactory performance on unseen data of different domains. Since the acquisition and annotation of medical data are costly and time-consuming, recent work focuses on domain adaptation and generalization to bridge the gap between data from different populations and scanners. In this paper, we propose two data augmentation methods that focus on improving the domain adaptation and generalization abilities of state-to-the-art cardiac segmentation models. In particular, our "Resol…
Universitat de Barcelona（巴塞罗那大学）；Barts Health NHS Trust（巴特兹健康国民保健服务信托基金）；Queen Mary University of London（伦敦玛丽女王大学）；Universitat Pompeu Fabra（庞培法布拉大学）；ICREA（加泰罗尼亚研究与高级研究院）
Accurate segmentation of the cardiac boundaries in late gadolinium enhancement magnetic resonance images (LGE-MRI) is a fundamental step for accurate quantification of scar tissue. However, while there are many solutions for automatic cardiac segmentation of cine images, the presence of scar tissue can make the correct delineation of the myocardium in LGE-MRI challenging even for human experts. As part of the Multi-Sequence Cardiac MR Segmentation Challenge, we propose a solution for LGE-MRI segmentation based on two components. First, a generative adversarial network is trained for the task o…
Dublin City University（都柏林城市大学）；University College Dublin（都柏林大学学院）
Methods that are resilient to artifacts in the cardiac magnetic resonance imaging (MRI) while performing ventricle segmentation, are crucial for ensuring quality in structural and functional analysis of those tissues. While there has been significant efforts on improving the quality of the algorithms, few works have tackled the harm that the artifacts generate in the predictions. In this work, we study fine tuning of pretrained networks to improve the resilience of previous methods to these artifacts. In our proposed method, we adopted the extensive usage of data augmentations that mimic those…
The University of Queensland（昆士兰大学）；CSIRO（联邦科学与工业研究组织）；Institute of Computing Technology, Chinese Academy of Sciences（中国科学院计算技术研究所）
Deep neural networks have been extensively studied for undersampled MRI reconstruction. While achieving state-of-the-art performance, they are trained and deployed specifically for one anatomy with limited generalization ability to another anatomy. Rather than building multiple models, a universal model that reconstructs images across different anatomies is highly desirable for efficient deployment and better generalization. Simply mixing images from multiple anatomies for training a single network does not lead to an ideal universal model due to the statistical shift among datasets of various…
Crop and Couple: cardiac image segmentation using interlinked specialist networks
Queen Mary University of London（伦敦玛丽女王大学）；Queen Mary's Digital Environment Research Institute (DERI)（伦敦玛丽女王大学数字环境研究所）；University College London（伦敦大学学院）
Imperial College London（帝国理工学院）；Royal Brompton Hospital（皇家布朗普顿医院）
Segmentation of cardiac fibrosis and scar are essential for clinical diagnosis and can provide invaluable guidance for the treatment of cardiac diseases. Late Gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) has been successful for its efficacy in guiding the clinical diagnosis and treatment reliably. For LGE CMR, many methods have demonstrated success in accurately segmenting scarring regions. Co-registration with other non-contrast-agent (non-CA) modalities, balanced steady-state free precession (bSSFP) and cine magnetic resonance imaging (MRI) for example, can further en…
