Unsupervised Multi-modal Style Transfer for Cardiac MR Segmentation
Biomedical Image Analysis Group, Imperial College London（伦敦帝国理工学院生物医学图像分析小组）；Data Science Institute, Imperial College London（伦敦帝国理工学院数据科学研究所）；Department of Medicine, Imperial College London（伦敦帝国理工学院医学院）
Chen Chen, Cheng Ouyang, Giacomo Tarroni, Jo Schlemper, Huaqi Qiu, Wenjia Bai, Daniel Rueckert
In this work, we present a fully automatic method to segment cardiac structures from late-gadolinium enhanced (LGE) images without using labelled LGE data for training, but instead by transferring the anatomical knowledge and features learned on annotated balanced steady-state free precession (bSSFP) images, which are easier to acquire. Our framework mainly consists of two neural networks: a multi-modal image translation network for style transfer and a cascaded segmentation network for image segmentation. The multi-modal image translation network generates realistic and diverse synthetic LGE images conditioned on a single annotated bSSFP image, forming a synthetic LGE training set. This set is then utilized to fine-tune the segmentation network pre-trained on labelled bSSFP images, achieving the goal of unsupervised LGE image segmentation. In particular, the proposed cascaded segmentation network is able to produce accurate segmentation by taking both shape prior and image appearance into account, achieving an average Dice score of 0.92 for the left ventricle, 0.83 for the myocardium, and 0.88 for the right ventricle on the test set.
Fudan University（复旦大学）；University of Oxford（牛津大学）；Chung-Ang University（中央大学）
Cardiac segmentation is in great demand for clinical practice. Due to the enormous labor of manual delineation, unsupervised segmentation is desired. The ill-posed optimization problem of this task is inherently challenging, requiring well-designed constraints. In this work, we propose an unsupervised framework for multi-class segmentation with both intensity and shape constraints. Firstly, we extend a conventional non-convex energy function as an intensity constraint and implement it with U-Net. For shape constraint, synthetic images are generated from anatomical labels via image-to-image tra…
Eindhoven University of Technology（埃因霍温理工大学）；Philips Research Laboratories（飞利浦研究实验室）；Philips Healthcare（飞利浦医疗）
There has been considerable interest in the MR physics-based simulation of a database of virtual cardiac MR images for the development of deep-learning analysis networks. However, the employment of such a database is limited or shows suboptimal performance due to the realism gap, missing textures, and the simplified appearance of simulated images. In this work we 1) provide image simulation on virtual XCAT subjects with varying anatomies, and 2) propose sim2real translation network to improve image realism. Our usability experiments suggest that sim2real data exhibits a good potential to augme…
Eindhoven University of Technology（埃因霍温理工大学）；Philips Research Laboratories（飞利浦研究院）；Philips Healthcare（飞利浦医疗）
We propose a hybrid controllable image generation method to synthesize anatomically meaningful 3D+t labeled Cardiac Magnetic Resonance (CMR) images. Our hybrid method takes the mechanistic 4D eXtended CArdiac Torso (XCAT) heart model as the anatomical ground truth and synthesizes CMR images via a data-driven Generative Adversarial Network (GAN). We employ the state-of-the-art SPatially Adaptive De-normalization (SPADE) technique for conditional image synthesis to preserve the semantic spatial information of ground truth anatomy. Using the parameterized motion model of the XCAT heart, we genera…
DECADE: A Temporally-Consistent Unsupervised Diffusion Model for Enhanced Rb-82 Dynamic Cardiac PET Image Denoising
Yale University（耶鲁大学）；Yale School of Medicine（耶鲁医学院）；Siemens Medical Solutions USA, Inc.（西门子医疗解决方案美国公司）；Inselspital, Bern University Hospital（伯尔尼大学医院Inselspital）；University of Bern（伯尔尼大学）；Department of Biomedical Engineering（生物医学工程系）；Department of Radiology and Biomedical Imaging（放射科和生物医学成像系）；Department of Medicine (Cardiology)（医学系（心脏病学））
ETH Zurich（苏黎世联邦理工学院）；TU Munich（慕尼黑工业大学）；Google（谷歌）
Transferring the style from one image onto another is a popular and widely studied task in computer vision. Yet, style transfer in the 3D setting remains a largely unexplored problem. To our knowledge, we propose the first learning-based approach for style transfer between 3D objects based on disentangled content and style representations. The proposed method can synthesize new 3D shapes both in the form of point clouds and meshes, combining the content and style of a source and target 3D model to generate a novel shape that resembles in style the target while retaining the source content. Fur…
Lenovo Research AI Lab（联想研究院人工智能实验室）；Kwai Inc.（快手公司）；Tianjin University（天津大学）；Cornell University（康奈尔大学）
Unsupervised text style transfer is full of challenges due to the lack of parallel data and difficulties in content preservation. In this paper, we propose a novel neural approach to unsupervised text style transfer, which we refer to as Cycle-consistent Adversarial autoEncoders (CAE) trained from non-parallel data. CAE consists of three essential components: (1) LSTM autoencoders that encode a text in one style into its latent representation and decode an encoded representation into its original text or a transferred representation into a style-transferred text, (2) adversarial style transfer…
Unsupervised style transfer that supports diverse input styles using only one trained generator is a challenging and interesting task in computer vision. This paper proposes a Multi-IlluStrator Style Generative Adversarial Network (MISS GAN) that is a multi-style framework for unsupervised image-to-illustration translation, which can generate styled yet content preserving images. The illustrations dataset is a challenging one since it is comprised of illustrations of seven different illustrators, hence contains diverse styles. Existing methods require to train several generators (as the number…
The Cyprus Institute（塞浦路斯研究所）；National and Kapodistrian University of Athens（雅典国立卡波季斯特里安大学）
In recent years, considerable advancements have been made in the area of Generative Adversarial Networks (GANs), particularly with the advent of style-based architectures that address many key shortcomings - both in terms of modeling capabilities and network interpretability. Despite these improvements, the adoption of such approaches in the domain of satellite imagery is not straightforward. Typical vision datasets used in generative tasks are well-aligned and annotated, and exhibit limited variability. In contrast, satellite imagery exhibits great spatial and spectral variability, wide prese…
Unsupervised image-to-image translation aims to learn the mapping between two visual domains with unpaired samples. Existing works focus on disentangling domain-invariant content code and domain-specific style code individually for multimodal purposes. However, less attention has been paid to interpreting and manipulating the translated image. In this paper, we propose to separate the content code and style code simultaneously in a unified framework. Based on the correlation between the latent features and the high-level domain-invariant tasks, the proposed framework demonstrates superior perf…
Southern University of Science and Technology（南方科技大学）；The University of Hong Kong（香港大学）
Various deep learning models have been developed to segment anatomical structures from medical images, but they typically have poor performance when tested on another target domain with different data distribution. Recently, unsupervised domain adaptation methods have been proposed to alleviate this so-called domain shift issue, but most of them are designed for scenarios with relatively small domain shifts and are likely to fail when encountering a large domain gap. In this paper, we propose DCDA, a novel cross-modality unsupervised domain adaptation framework for tasks with large domain shif…
University of Trento（特伦托大学）；Tencent AI Lab（腾讯人工智能实验室）；Fondazione Bruno Kessler（布鲁诺·凯塞勒基金会）
Image-to-Image (I2I) multi-domain translation models are usually evaluated also using the quality of their semantic interpolation results. However, state-of-the-art models frequently show abrupt changes in the image appearance during interpolation, and usually perform poorly in interpolations across domains. In this paper, we propose a new training protocol based on three specific losses which help a translation network to learn a smooth and disentangled latent style space in which: 1) Both intra- and inter-domain interpolations correspond to gradual changes in the generated images and 2) The …
We propose the use of unsupervised learning to train projection networks that project onto the latent space of an already trained generator. We apply our method to a trained StyleGAN, and use our projection network to perform image super-resolution and clustering of images into semantically identifiable groups.
Unsupervised image-to-image translation is an important and challenging problem in computer vision. Given an image in the source domain, the goal is to learn the conditional distribution of corresponding images in the target domain, without seeing any pairs of corresponding images. While this conditional distribution is inherently multimodal, existing approaches make an overly simplified assumption, modeling it as a deterministic one-to-one mapping. As a result, they fail to generate diverse outputs from a given source domain image. To address this limitation, we propose a Multimodal Unsupervi…
Indian Institute of Information Technology, Sri City（印度信息技术学院，斯里城）
Image to Image Translation (I2I) is a challenging computer vision problem used in numerous domains for multiple tasks. Recently, ophthalmology became one of the major fields where the application of I2I is increasing rapidly. One such application is the generation of synthetic retinal optical coherence tomographic (OCT) scans. Existing I2I methods require training of multiple models to translate images from normal scans to a specific pathology: limiting the use of these models due to their complexity. To address this issue, we propose an unsupervised multi-domain I2I network with pre-trained s…
Peking University（北京大学）；Peking University First Hospital（北京大学第一医院）；MGH/BWH Center for Clinical Data Science（麻省总医院/布莱根妇女医院临床数据科学中心）
Segmenting coronary arteries is challenging, as classic unsupervised methods fail to produce satisfactory results and modern supervised learning (deep learning) requires manual annotation which is often time-consuming and can some time be infeasible. To solve this problem, we propose a knowledge transfer based shape-consistent generative adversarial network (SC-GAN), which is an annotation-free approach that uses the knowledge from publicly available annotated fundus dataset to segment coronary arteries. The proposed network is trained in an end-to-end fashion, generating and segmenting synthe…
Unsupervised image-to-image translation intends to learn a mapping of an image in a given domain to an analogous image in a different domain, without explicit supervision of the mapping. Few-shot unsupervised image-to-image translation further attempts to generalize the model to an unseen domain by leveraging example images of the unseen domain provided at inference time. While remarkably successful, existing few-shot image-to-image translation models find it difficult to preserve the structure of the input image while emulating the appearance of the unseen domain, which we refer to as the con…
Yonsei University（延世大学）；Agency for Defense Development (ADD)（国防科学研究所）
We present a novel unsupervised framework for instance-level image-to-image translation. Although recent advances have been made by incorporating additional object annotations, existing methods often fail to handle images with multiple disparate objects. The main cause is that, during inference, they apply a global style to the whole image and do not consider the large style discrepancy between instance and background, or within instances. To address this problem, we propose a class-aware memory network that explicitly reasons about local style variations. A key-values memory structure, with a…
We introduce a data-driven approach for unsupervised video retargeting that translates content from one domain to another while preserving the style native to a domain, i.e., if contents of John Oliver's speech were to be transferred to Stephen Colbert, then the generated content/speech should be in Stephen Colbert's style. Our approach combines both spatial and temporal information along with adversarial losses for content translation and style preservation. In this work, we first study the advantages of using spatiotemporal constraints over spatial constraints for effective retargeting. We t…
Synthetic Cardiac MRI Image Generation using Deep Generative Models
Department of Computer Engineering（计算机工程系）；University of Peradeniya（珀德尼亚大学）；University of Maryland（马里兰大学）；Department of Holistic Systems（整体系统系）；SimulaMet；Oslo, Norway（挪威奥斯陆）
Recent studies have shown remarkable success in the unsupervised image to image (I2I) translation. However, due to the imbalance in the data, learning joint distribution for various domains is still very challenging. Although existing models can generate realistic target images, it's difficult to maintain the structure of the source image. In addition, training a generative model on large data in multiple domains requires a lot of time and computer resources. To address these limitations, we propose a novel image-to-image translation method that generates images of the target domain by finetun…
Deep models often suffer from severe performance drop due to the appearance shift in the real clinical setting. Most of the existing learning-based methods rely on images from multiple sites/vendors or even corresponding labels. However, collecting enough unknown data to robustly model segmentation cannot always hold since the complex appearance shift caused by imaging factors in daily application. In this paper, we propose a novel style-invariant method for cardiac image segmentation. Based on the zero-shot style transfer to remove appearance shift and test-time augmentation to explore divers…
IST Austria（奥地利科学技术研究所）；Google Brain（谷歌大脑）；Deepmind（深度思维）；Google Research（谷歌研究院）
Style transfer usually refers to the task of applying color and texture information from a specific style image to a given content image while preserving the structure of the latter. Here we tackle the more generic problem of semantic style transfer: given two unpaired collections of images, we aim to learn a mapping between the corpus-level style of each collection, while preserving semantic content shared across the two domains. We introduce XGAN ("Cross-GAN"), a dual adversarial autoencoder, which captures a shared representation of the common domain semantic content in an unsupervised way,…
Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）
Automatic artistic text generation is an emerging topic which receives increasing attention due to its wide applications. The artistic text can be divided into three components, content, font, and texture, respectively. Existing artistic text generation models usually focus on manipulating one aspect of the above components, which is a sub-optimal solution for controllable general artistic text generation. To remedy this issue, we propose a novel approach, namely GenText, to achieve general artistic text style transfer by separably migrating the font and texture styles from the different sourc…
Congenital heart disease is considered as one the most common groups of congenital malformations which affects $6-11$ per $1000$ newborns. In this work, an automated framework for detection of cardiac anomalies during ultrasound screening is proposed and evaluated on the example of Hypoplastic Left Heart Syndrome (HLHS), a sub-category of congenital heart disease. We propose an unsupervised approach that learns healthy anatomy exclusively from clinically confirmed normal control patients. We evaluate a number of known anomaly detection frameworks together with a model architecture based on the…
Deep learning (DL)-based models have demonstrated good performance in medical image segmentation. However, the models trained on a known dataset often fail when performed on an unseen dataset collected from different centers, vendors and disease populations. In this work, we present a random style transfer network to tackle the domain generalization problem for multi-vendor and center cardiac image segmentation. Style transfer is used to generate training data with a wider distribution/ heterogeneity, namely domain augmentation. As the target domain could be unknown, we randomly generate a mod…
In this paper, we propose a novel framework to translate a portrait photo-face into an anime appearance. Our aim is to synthesize anime-faces which are style-consistent with a given reference anime-face. However, unlike typical translation tasks, such anime-face translation is challenging due to complex variations of appearances among anime-faces. Existing methods often fail to transfer the styles of reference anime-faces, or introduce noticeable artifacts/distortions in the local shapes of their generated faces. We propose AniGAN, a novel GAN-based translator that synthesizes high-quality ani…
Institute of Computing Technology（计算技术研究所）；University of Chinese Academy of Sciences（中国科学院大学）；Huawei Technologies（华为技术有限公司）；University of Science and Technology of China（中国科学技术大学）
In recent years, creative content generations like style transfer and neural photo editing have attracted more and more attention. Among these, cartoonization of real-world scenes has promising applications in entertainment and industry. Different from image translations focusing on improving the style effect of generated images, video cartoonization has additional requirements on the temporal consistency. In this paper, we propose a spatially-adaptive semantic alignment framework with perceptual motion consistency for coherent video cartoonization in an unsupervised manner. The semantic align…
This study proposes an end-to-end unsupervised diffeomorphic deformable registration framework based on moving mesh parameterization. Using this parameterization, a deformation field can be modeled with its transformation Jacobian determinant and curl of end velocity field. The new model of the deformation field has three important advantages; firstly, it relaxes the need for an explicit regularization term and the corresponding weight in the cost function. The smoothness is implicitly embedded in the solution which results in a physically plausible deformation field. Secondly, it guarantees d…
Texas A&M University（德克萨斯农工大学）；Sidra Medicine（锡德拉医学中心）；Weill Cornell Medical College（威尔康奈尔医学院）
This paper presents a novel machine learning framework to consistently detect, localize and rate congenital cleft lip anomalies in human faces. The goal is to provide a universal, objective measure of facial differences and reconstructive surgical outcomes that matches human judgments. The proposed method employs the StyleGAN2 generative adversarial network with model adaptation to produce normalized transformations of cleft-affected faces in order to allow for subsequent measurement of deformity using a pixel-wise subtraction approach. The complete pipeline of the proposed framework consists …
Pengcheng Laboratory（鹏城实验室）；Shenzhen University（深圳大学）；University of Nottingham（诺丁汉大学）
Facial attributes in StyleGAN generated images are entangled in the latent space which makes it very difficult to independently control a specific attribute without affecting the others. Supervised attribute editing requires annotated training data which is difficult to obtain and limits the editable attributes to those with labels. Therefore, unsupervised attribute editing in an disentangled latent space is key to performing neat and versatile semantic face editing. In this paper, we present a new technique termed Structure-Texture Independent Architecture with Weight Decomposition and Orthog…
Institute of Computing Technology, Chinese Academy of Sciences（中国科学院计算技术研究所）；University of Chinese Academy of Sciences（中国科学院大学）；University of California, Los Angeles（加州大学洛杉矶分校）；Lenovo Research（联想研究院）；Lenovo Ltd.（联想有限公司）
Accurate segmentation of cardiac structures can assist doctors to diagnose diseases, and to improve treatment planning, which is highly demanded in the clinical practice. However, the shortage of annotation and the variance of the data among different vendors and medical centers restrict the performance of advanced deep learning methods. In this work, we present a fully automatic method to segment cardiac structures including the left (LV) and right ventricle (RV) blood pools, as well as for the left ventricular myocardium (MYO) in MRI volumes. Specifically, we design a semi-supervised learnin…
Disentangling factors of variation within data has become a very challenging problem for image generation tasks. Current frameworks for training a Generative Adversarial Network (GAN), learn to disentangle the representations of the data in an unsupervised fashion and capture the most significant factors of the data variations. However, these approaches ignore the principle of content and style disentanglement in image generation, which means their learned latent code may alter the content and style of the generated images at the same time. This paper describes the Style and Content Disentangl…
Shanghai Artificial Intelligence Laboratory（上海人工智能实验室）；East China Normal University（华东师范大学）
Automatic font generation without human experts is a practical and significant problem, especially for some languages that consist of a large number of characters. Existing methods for font generation are often in supervised learning. They require a large number of paired data, which are labor-intensive and expensive to collect. In contrast, common unsupervised image-to-image translation methods are not applicable to font generation, as they often define style as the set of textures and colors. In this work, we propose a robust deformable generative network for unsupervised font generation (ab…
King Abdullah University of Science and Technology（阿卜杜拉国王科技大学）
This work introduced a novel GAN architecture for unsupervised image translation on the task of face style transform. A spectral attention-based mechanism is embedded into the design along with spatial attention on the image contents. We proved that neural network has the potential of learning complex transformations such as Fourier transform, within considerable computational cost. The model is trained and tested in comparison to the baseline model, which only uses spatial attention. The performance improvement of our approach is significant especially when the source and target domain includ…
Image-to-Image (I2I) translation is a heated topic in academia, and it also has been applied in real-world industry for tasks like image synthesis, super-resolution, and colorization. However, traditional I2I translation methods train data in two or more domains together. This requires lots of computation resources. Moreover, the results are of lower quality, and they contain many more artifacts. The training process could be unstable when the data in different domains are not balanced, and modal collapse is more likely to happen. We proposed a new I2I translation method that generates a new m…
University of Science and Technology of China（中国科学技术大学）；HKUST（香港科技大学）；Microsoft Research Asia（微软亚洲研究院）；EIT（欧洲创新与技术学院）
This paper addresses the unsupervised learning of content-style decomposed representation. We first give a definition of style and then model the content-style representation as a token-level bipartite graph. An unsupervised framework, named Retriever, is proposed to learn such representations. First, a cross-attention module is employed to retrieve permutation invariant (P.I.) information, defined as style, from the input data. Second, a vector quantization (VQ) module is used, together with man-induced constraints, to produce interpretable content tokens. Last, an innovative link attention m…
Unsupervised domain adaptation is useful in medical image segmentation. Particularly, when ground truths of the target images are not available, domain adaptation can train a target-specific model by utilizing the existing labeled images from other modalities. Most of the reported works mapped images of both the source and target domains into a common latent feature space, and then reduced their discrepancy either implicitly with adversarial training or explicitly by directly minimizing a discrepancy metric. In this work, we propose a new framework, where the latent features of both domains ar…
Image-to-image translation aims to learn a mapping between different groups of visually distinguishable images. While recent methods have shown impressive ability to change even intricate appearance of images, they still rely on domain labels in training a model to distinguish between distinct visual features. Such dependency on labels often significantly limits the scope of applications since consistent and high-quality labels are expensive. Instead, we wish to capture visual features from images themselves and apply them to enable realistic translation without human-generated labels. To this…
We propose a method to disentangle linear-encoded facial semantics from StyleGAN without external supervision. The method derives from linear regression and sparse representation learning concepts to make the disentangled latent representations easily interpreted as well. We start by coupling StyleGAN with a stabilized 3D deformable facial reconstruction method to decompose single-view GAN generations into multiple semantics. Latent representations are then extracted to capture interpretable facial semantics. In this work, we make it possible to get rid of labels for disentangling meaningful f…
University of Edinburgh（爱丁堡大学）；Imperial College London（帝国理工学院）；University of Essex（埃塞克斯大学）
Magnetic Resonance Imaging (MRI) typically recruits multiple sequences (defined here as "modalities"). As each modality is designed to offer different anatomical and functional clinical information, there are evident disparities in the imaging content across modalities. Inter- and intra-modality affine and non-rigid image registration is an essential medical image analysis process in clinical imaging, as for example before imaging biomarkers need to be derived and clinically evaluated across different MRI modalities, time phases and slices. Although commonly needed in real clinical scenarios, …
Unsupervised domain adaptation (UDA) methods intend to reduce the gap between source and target domains by using unlabeled target domain and labeled source domain data, however, in the medical domain, target domain data may not always be easily available, and acquiring new samples is generally time-consuming. This restricts the development of UDA methods for new domains. In this paper, we explore the potential of UDA in a more challenging while realistic scenario where only one unlabeled target patient sample is available. We call it Few-shot Unsupervised Domain adaptation (FUDA). We first gen…
Heidelberg University Hospital（海德堡大学医院）；DZHK (German Centre for Cardiovascular Research)（德国心血管研究中心）；UT Southwestern Medical Center（德克萨斯大学西南医学中心）；German Competence Network for Congenital Heart Defects（德国先天性心脏病能力网络）
Anisotropic multi-slice Cardiac Magnetic Resonance (CMR) Images are conventionally acquired in patient-specific short-axis (SAX) orientation. In specific cardiovascular diseases that affect right ventricular (RV) morphology, acquisitions in standard axial (AX) orientation are preferred by some investigators, due to potential superiority in RV volume measurement for treatment planning. Unfortunately, due to the rare occurrence of these diseases, data in this domain is scarce. Recent research in deep learning-based methods mainly focused on SAX CMR images and they had proven to be very successfu…
Huazhong University of Science & Technology（华中科技大学）；University of Technology Sydney（悉尼科技大学）；Farsee2 Tech. Co.（Farsee2科技公司）；Baidu Research（百度研究院）
We aim at the problem named One-Shot Unsupervised Domain Adaptation. Unlike traditional Unsupervised Domain Adaptation, it assumes that only one unlabeled target sample can be available when learning to adapt. This setting is realistic but more challenging, in which conventional adaptation approaches are prone to failure due to the scarce of unlabeled target data. To this end, we propose a novel Adversarial Style Mining approach, which combines the style transfer module and task-specific module into an adversarial manner. Specifically, the style transfer module iteratively searches for harder …
Amsterdam University Medical Centers（阿姆斯特丹大学医学中心）；University of Amsterdam（阿姆斯特丹大学）；Amsterdam Cardiovascular Sciences（阿姆斯特丹心血管科学研究所）
Although high resolution isotropic 3D medical images are desired in clinical practice, their acquisition is not always feasible. Instead, lower resolution images are upsampled to higher resolution using conventional interpolation methods. Sophisticated learning-based super-resolution approaches are frequently unavailable in clinical setting, because such methods require training with high-resolution isotropic examples. To address this issue, we propose a learning-based super-resolution approach that can be trained using solely anisotropic images, i.e. without high-resolution ground truth data.…
Existing unsupervised video-to-video translation methods fail to produce translated videos which are frame-wise realistic, semantic information preserving and video-level consistent. In this work, we propose UVIT, a novel unsupervised video-to-video translation model. Our model decomposes the style and the content, uses the specialized encoder-decoder structure and propagates the inter-frame information through bidirectional recurrent neural network (RNN) units. The style-content decomposition mechanism enables us to achieve style consistent video translation results as well as provides us wit…
University of Kansas（堪萨斯大学）；Rochester Institute of Technology（罗切斯特理工学院）
Patient-specific left ventricle (LV) myocardial models have the potential to be used in a variety of clinical scenarios for improved diagnosis and treatment plans. Cine cardiac magnetic resonance (MR) imaging provides high resolution images to reconstruct patient-specific geometric models of the LV myocardium. With the advent of deep learning, accurate segmentation of cardiac chambers from cine cardiac MR images and unsupervised learning for image registration for cardiac motion estimation on a large number of image datasets is attainable. Here, we propose a deep leaning-based framework for th…
Accurate cardiac computing, analysis and modeling from multi-modality images are important for the diagnosis and treatment of cardiac disease. Late gadolinium enhancement magnetic resonance imaging (LGE MRI) is a promising technique to visualize and quantify myocardial infarction (MI) and atrial scars. Automating quantification of MI and atrial scars can be challenging due to the low image quality and complex enhancement patterns of LGE MRI. Moreover, compared with the other sequences LGE MRIs with gold standard labels are particularly limited, which represents another obstacle for developing …
Automatic and accurate segmentation of the ventricles and myocardium from multi-sequence cardiac MRI (CMR) is crucial for the diagnosis and treatment management for patients suffering from myocardial infarction (MI). However, due to the existence of domain shift among different modalities of datasets, the performance of deep neural networks drops significantly when the training and testing datasets are distinct. In this paper, we propose an unsupervised domain alignment method to explicitly alleviate the domain shifts among different modalities of CMR sequences, \emph{e.g.,} bSSFP, LGE, and T2…
