Unsupervised domain adaptation approaches have recently succeeded in various medical image segmentation tasks. The reported works often tackle the domain shift problem by aligning the domain-invariant features and minimizing the domain-specific discrepancies. That strategy works well when the difference between a specific domain and between different domains is slight. However, the generalization ability of these models on diverse imaging modalities remains a significant challenge. This paper introduces UDA-VAE++, an unsupervised domain adaptation framework for cardiac segmentation. We show that the evidence lower bound of VAE-based domain adaptation penalizes the mutual information between the image and the latent space, including the structure information that segmentation relies on. Maximizing the structure mutual information removes this penalty on the structure information, while the remaining information is still compressed. To estimate this term, we develop a novel Structure Mutual Information Estimation (SMIE) block with a global estimator, a local estimator, and a prior information matching estimator to maximize the mutual information between the reconstruction and segmentation tasks. Specifically, we design a novel sequential reparameterization scheme that enables information flow and variance correction from the low-resolution latent space to the high-resolution latent space. Comprehensive experiments on benchmark cardiac segmentation datasets demonstrate that our model outperforms previous state-of-the-art qualitatively and quantitatively. The code is available at https://github.com/LOUEY233/Toward-Mutual-Information
We propose a hypothesis disparity regularized mutual information maximization~(HDMI) approach to tackle unsupervised hypothesis transfer -- as an effort towards unifying hypothesis transfer learning (HTL) and unsupervised domain adaptation (UDA) -- where the knowledge from a source domain is transferred solely through hypotheses and adapted to the target domain in an unsupervised manner. In contrast to the prevalent HTL and UDA approaches that typically use a single hypothesis, HDMI employs multiple hypotheses to leverage the underlying distributions of the source and target hypotheses. To bet…
Huazhong University of Science and Technology（华中科技大学）
Multimodal sentiment analysis (MSA) is a fundamental complex research problem due to the heterogeneity gap between different modalities and the ambiguity of human emotional expression. Although there have been many successful attempts to construct multimodal representations for MSA, there are still two challenges to be addressed: 1) A more robust multimodal representation needs to be constructed to bridge the heterogeneity gap and cope with the complex multimodal interactions, and 2) the contextual dynamics must be modeled effectively throughout the information flow. In this work, we propose a…
A variety of graph neural networks (GNNs) frameworks for representation learning on graphs have been recently developed. These frameworks rely on aggregation and iteration scheme to learn the representation of nodes. However, information between nodes is inevitably lost in the scheme during learning. In order to reduce the loss, we extend the GNNs frameworks by exploring the aggregation and iteration scheme in the methodology of mutual information. We propose a new approach of enlarging the normal neighborhood in the aggregation of GNNs, which aims at maximizing mutual information. Based on a …
The University of British Columbia（不列颠哥伦比亚大学）；Shenzhen Polytechnic（深圳职业技术大学）
Recent advances in unsupervised domain adaptation have shown that mitigating the domain divergence by extracting the domain-invariant representation could significantly improve the generalization of a model to an unlabeled data domain. Nevertheless, the existing methods fail to effectively preserve the representation that is private to the label-missing domain, which could adversely affect the generalization. In this paper, we propose an approach to preserve such representation so that the latent distribution of the unlabeled domain could represent both the domain-invariant features and the in…
Klinikum Rechts der Isar, Technical University of Munich（慕尼黑工业大学伊萨尔河右岸医院）；Imperial College London（伦敦帝国理工学院）；University Hospital of Tübingen（图宾根大学医院）
Motion-compensated MR reconstruction (MCMR) is a powerful concept with considerable potential, consisting of two coupled sub-problems: Motion estimation, assuming a known image, and image reconstruction, assuming known motion. In this work, we propose a learning-based self-supervised framework for MCMR, to efficiently deal with non-rigid motion corruption in cardiac MR imaging. Contrary to conventional MCMR methods in which the motion is estimated prior to reconstruction and remains unchanged during the iterative optimization process, we introduce a dynamic motion estimation process and embed …
Singapore University of Technology and Design（新加坡科技设计大学）；Monash University（蒙纳士大学）；University of Dayton（代顿大学）
In this paper, we adopt the maximizing mutual information (MI) approach to tackle the problem of unsupervised learning of binary hash codes for efficient cross-modal retrieval. We proposed a novel method, dubbed Cross-Modal Info-Max Hashing (CMIMH). First, to learn informative representations that can preserve both intra- and inter-modal similarities, we leverage the recent advances in estimating variational lower-bound of MI to maximize the MI between the binary representations and input features and between binary representations of different modalities. By jointly maximizing these MIs under…
ÉTS Montreal（蒙特利尔高等技术学院）；CentraleSupélec（巴黎中央理工-高等电力学院）；CNRS（法国国家科学研究中心）；Université Paris Saclay（巴黎萨克雷大学）；Laboratoire des Signaux et Systèmes（信号与系统实验室）
We introduce Transductive Infomation Maximization (TIM) for few-shot learning. Our method maximizes the mutual information between the query features and their label predictions for a given few-shot task, in conjunction with a supervision loss based on the support set. We motivate our transductive loss by deriving a formal relation between the classification accuracy and mutual-information maximization. Furthermore, we propose a new alternating-direction solver, which substantially speeds up transductive inference over gradient-based optimization, while yielding competitive accuracy. We also p…
Beijing University of Posts and Telecommunications（北京邮电大学）；Canon Information Technology (Beijing) Co., Ltd（佳能信息技术（北京）有限公司）
Racial bias is an important issue in biometric, but has not been thoroughly studied in deep face recognition. In this paper, we first contribute a dedicated dataset called Racial Faces in-the-Wild (RFW) database, on which we firmly validated the racial bias of four commercial APIs and four state-of-the-art (SOTA) algorithms. Then, we further present the solution using deep unsupervised domain adaptation and propose a deep information maximization adaptation network (IMAN) to alleviate this bias by using Caucasian as source domain and other races as target domains. This unsupervised method simu…
CSAIL, Massachusetts Institute of Technology（麻省理工学院计算机科学与人工智能实验室）；MIT Lincoln Laboratory（麻省理工学院林肯实验室）；Beth Israel Deaconess Medical Center, Harvard Medical School（哈佛医学院贝斯以色列女执事医疗中心）
We propose and demonstrate a representation learning approach by maximizing the mutual information between local features of images and text. The goal of this approach is to learn useful image representations by taking advantage of the rich information contained in the free text that describes the findings in the image. Our method trains image and text encoders by encouraging the resulting representations to exhibit high local mutual information. We make use of recent advances in mutual information estimation with neural network discriminators. We argue that the sum of local mutual information…
A major endeavor of computer vision is to represent, understand and extract structure from 3D data. Towards this goal, unsupervised learning is a powerful and necessary tool. Most current unsupervised methods for 3D shape analysis use datasets that are aligned, require objects to be reconstructed and suffer from deteriorated performance on downstream tasks. To solve these issues, we propose to extend the InfoMax and contrastive learning principles on 3D shapes. We show that we can maximize the mutual information between 3D objects and their "chunks" to improve the representations in aligned da…
In this work, we propose a mutual information (MI) based unsupervised domain adaptation (UDA) method for the cross-domain nuclei segmentation. Nuclei vary substantially in structure and appearances across different cancer types, leading to a drop in performance of deep learning models when trained on one cancer type and tested on another. This domain shift becomes even more critical as accurate segmentation and quantification of nuclei is an essential histopathology task for the diagnosis/ prognosis of patients and annotating nuclei at the pixel level for new cancer types demands extensive eff…
The novel 2019 Coronavirus (COVID-19) infection has spread world widely and is currently a major healthcare challenge around the world. Chest Computed Tomography (CT) and X-ray images have been well recognized to be two effective techniques for clinical COVID-19 disease diagnoses. Due to faster imaging time and considerably lower cost than CT, detecting COVID-19 in chest X-ray (CXR) images is preferred for efficient diagnosis, assessment and treatment. However, considering the similarity between COVID-19 and pneumonia, CXR samples with deep features distributed near category boundaries are eas…
Multimodal image-to-image translation (I2IT) aims to learn a conditional distribution that explores multiple possible images in the target domain given an input image in the source domain. Conditional generative adversarial networks (cGANs) are often adopted for modeling such a conditional distribution. However, cGANs are prone to ignore the latent code and learn a unimodal distribution in conditional image synthesis, which is also known as the mode collapse issue of GANs. To solve the problem, we propose a simple yet effective method that explicitly estimates and maximizes the mutual informat…
Accurate and robust whole heart substructure segmentation is crucial in developing clinical applications, such as computer-aided diagnosis and computer-aided surgery. However, segmentation of different heart substructures is challenging because of inadequate edge or boundary information, the complexity of the background and texture, and the diversity in different substructures' sizes and shapes. This article proposes a framework for multi-class whole heart segmentation employing non-rigid registration-based probabilistic atlas incorporating the Bayesian framework. We also propose a non-rigid r…
Unsupervised pre-training has been proven as an effective approach to boost various downstream tasks given limited labeled data. Among various methods, contrastive learning learns a discriminative representation by constructing positive and negative pairs. However, it is not trivial to build reasonable pairs for a segmentation task in an unsupervised way. In this work, we propose a novel unsupervised pre-training framework that avoids the drawback of contrastive learning. Our framework consists of two principles: unsupervised over-segmentation as a pre-train task using mutual information maxim…
Multimodal image alignment is the process of finding spatial correspondences between images formed by different imaging techniques or under different conditions, to facilitate heterogeneous data fusion and correlative analysis. The information-theoretic concept of mutual information (MI) is widely used as a similarity measure to guide multimodal alignment processes, where most works have focused on local maximization of MI that typically works well only for small displacements; this points to a need for global maximization of MI, which has previously been computationally infeasible due to the …
The Chinese University of Hong Kong（香港中文大学）；Department of Computer Science and Engineering, The Chinese University of Hong Kong（香港中文大学计算机科学与工程学系）；Guangdong Provincial Key Laboratory of Computer Vision and Virtual Reality Technology（广东省计算机视觉与虚拟现实技术重点实验室）；Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）
The success of deep convolutional neural networks is partially attributed to the massive amount of annotated training data. However, in practice, medical data annotations are usually expensive and time-consuming to be obtained. Considering multi-modality data with the same anatomic structures are widely available in clinic routine, in this paper, we aim to exploit the prior knowledge (e.g., shape priors) learned from one modality (aka., assistant modality) to improve the segmentation performance on another modality (aka., target modality) to make up annotation scarcity. To alleviate the learni…
Koc University（科奇大学）；Google Cloud AI Research（谷歌云人工智能研究部）
Self-supervised learning allows AI systems to learn effective representations from large amounts of data using tasks that do not require costly labeling. Mode collapse, i.e., the model producing identical representations for all inputs, is a central problem to many self-supervised learning approaches, making self-supervised tasks, such as matching distorted variants of the inputs, ineffective. In this article, we argue that a straightforward application of information maximization among alternative latent representations of the same input naturally solves the collapse problem and achieves comp…
