Digital image devices have been widely applied in many fields, including scientific imaging, recognition of individuals, and remote sensing. As the application of these imaging technologies to autonomous driving and measurement, image noise generated when observation cannot be performed with a sufficient dose has become a major problem. Machine learning denoise technology is expected to be the solver of this problem, but there are the following problems. Here we report, artifacts generated by machine learning denoise in ultra-low dose observation using an in-situ observation video of an electron microscope as an example. And as a method to solve this problem, we propose a method to decompose a time series image into a 2D image of the spatial axis and time to perform machine learning denoise. Our method opens new avenues accurate and stable reconstruction of continuous high-resolution images from low-dose imaging in science, industry, and life.
MDAA-Diff: CT-Guided Multi-Dose Adaptive Attention Diffusion Model for PET Denoising
School of Biomedical Engineering, Southern Medical University(南方医科大学生物医学工程学院);School of Biomedical Engineering, Shanghai Jiao Tong University(上海交通大学生物医学工程学院);Nanfang PET Center, Nanfang Hospital Southern Medical University(南方医科大学南芳医院PET中心)
ASCON: Anatomy-aware Supervised Contrastive Learning Framework for Low-dose CT Denoising
Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University(复旦大学类脑智能科学与技术研究院);School of Cyber Science and Engineering, Sichuan University(四川大学网络空间安全学院)
Low-dose CT Denoising with Language-engaged Dual-space Alignment
Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University(复旦大学脑智能科学与技术研究院);Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute(伦斯勒理工学院生物技术与跨学科研究中心)
WIA-LD2ND: Wavelet-based Image Alignment for Self-supervised Low-Dose CT Denoising
School of Computer Science, Wuhan University(武汉大学计算机学院);School of Computer Science, Central China Normal University(华中师范大学计算机学院);University of Louisville(路易斯维尔大学)
Rethinking Cross-Dose PET Denoising: Mitigating Averaging Effects via Residual Noise Learning
IWR, Heidelberg University(海德堡大学IWR);Silicon Austria Labs(Silicon Austria实验室);College of Medicine and Biological Information Engineering, Key Laboratory of Intelligent Computing in Medical Image, Ministry of Education, Northeastern University(医学与生物信息工程学院,医学图像智能计算教育部重点实验室,东北大学);Department of Epidemiology & Global Health, Umeå University(流行病学与全球健康系,乌梅大学)
School of Statistics and Data Science, Nankai University(南开大学统计与数据科学学院);The First Affiliated Hospital of Xi’an Jiaotong University(西安交通大学第一附属医院);Shanxi Engineering Research Center of Computational Imaging and Medical Intelligence(山西省计算成像与医学智能工程研究中心)
Patch-wise Deep Metric Learning for Unsupervised Low-Dose CT Denoising
Korea Advanced Institute of Science and Technology (KAIST)(韩国科学技术院(KAIST));VUNO Corp.(VUNO公司);Chungnam National University College of Medicine(忠南大学医学院);Chungnam National University Hospital(忠南大学医院)
Noise Conscious Training of Non Local Neural Network powered by Self Attentive Spectral Normalized Markovian Patch GAN for Low Dose CT Denoising
在医疗实践中使用计算机断层扫描(CT)成像的爆炸性增长,提高了公众对患者相关辐射剂量的关注。然而,减少辐射剂量导致噪声和伪影增加,这不利地降低了扫描的可解释性。因此,一种先进的图像重建算法来提高低剂量ct的诊断性能成为研究人员的主要关注点,但由于该问题的不适定性,这具有挑战性。近年来,基于深度学习的技术已经成为低剂量CT(LDCT)去噪的主要方法。然而,仍然存在一些常见的瓶颈,这阻碍了基于深度学习的技术提供最佳性能。在这项研究中,我们试图减轻这些问题与三个新的吸积。首先,我们提出了一种新的卷积模块作为第一次尝试利用CT图像的邻域相似性去噪任务。我们提出的模块有助于提高去噪的显著幅度。接下来,我们转向CT噪声的非平稳性问题,并引入了一种新的噪声感知均方误差损失用于LDCT去噪。此外,上述损失也有助于减轻使用图像补丁训练CT去噪网络时所需的繁重工作。最后,我们提出了一种新的CT去噪任务的函数。传统的香草型协议往往忽略了精细的结构细节,而专注于全球协议。我们提出的神经网络利用自注意力和像素级GANs来恢复LDCT图像的诊断质量。我们的方法在2016年NIH-AAPM-Mayo Clinic低剂量CT Grand Challenge的公开数据集上进行了验证,其表现明显优于现有的最先进方法。
End-to-end Triple-domain PET Enhancement: A Hybrid Denoising-and-reconstruction Framework for Reconstructing Standard-dose PET Images from Low-dose PET Sinograms
ShanghaiTech University(上海科技大学);Shanghai United Imaging Intelligence Co., Ltd.(上海联影智能医疗科技有限公司);Shanghai Clinical Research and Trial Center(上海临床研究与试验中心);Shanghai Artificial Intelligence Laboratory(上海人工智能实验室)
提出端到端三域 TriPLET 框架,融合投影域去噪、小波域重建和图像域对抗评估,从低剂量 PET 正弦图恢复标准剂量图像,并取得最优相似度与信噪比。
PFCM: Poisson flow consistency models for low-dose CT image denoising
Stanford University(斯坦福大学);KTH Royal Institute of Technology(瑞典皇家理工学院);Karolinska University Hospital(卡罗林斯卡大学医院);GE HealthCare(GE医疗);Rensselaer Polytechnic Institute(伦斯勒理工学院)
FoundDiff: Foundational Diffusion Model for Generalizable Low-Dose CT Denoising
Institute of Science and Technology for Brain-inspired Intelligence and MOE Frontiers Center for Brain Science, Fudan University(脑启发智能科学技术研究所和脑科学前沿中心,复旦大学);Shanghai Key Lab of Intelligent Information Processing, School of Computer Science, Fudan University(智能信息处理上海市重点实验室,复旦大学计算机科学学院);School of Cyber Science and Engineering, Sichuan University(四川大学网络科学与工程学院);School of Biomedical Engineering, Shanghai Jiao Tong University(上海交通大学生物医学工程学院)
GCN-MIF: Graph Convolutional Network with Multi-Information Fusion for Low-dose CT Denoising
University of Electronic Science and Technology of China(电子科技大学);West China Hospital, Sichuan University(四川大学华西医院);West China No.4 Hospital, Sichuan University(四川大学华西第四医院)
Cycle-Constrained Adversarial Denoising Convolutional Network for PET Image Denoising: Multi-Dimensional Validation on Large Datasets with Reader Study and Real Low-Dose Data
Low-dose CT denoising with convolutional neural network
College of Computer Science, Sichuan University(四川大学计算机学院);National Key Laboratory of Fundamental Science on Synthetic Vision, Sichuan University(四川大学视觉合成图形图像技术国家级重点实验室);Rensselaer Polytechnic Institute(伦斯勒理工学院)
Friedrich-Alexander Universität Erlangen-Nürnberg (FAU)(埃尔朗根-纽伦堡弗里德里希-亚历山大大学);Siemens Healthcare GmbH(西门子医疗有限公司)
深度神经网络在低剂量CT去噪方面取得了巨大成功。然而,这些深度神经网络中的大多数都有几十万个可训练的参数。这与神经网络固有的非线性相结合,使得深度神经网络难以理解,责任心低。在这项研究中,我们介绍了JBFnet,神经网络的低剂量CT去噪。JBFnet的体系结构实现了迭代双边滤波。联合双边滤波器(JBF)的滤波器函数是通过浅层卷积网络学习的。引导图像由深度神经网络估计。JBFnet分为四个滤波块,每个滤波块执行联合双边滤波。每个JBF块由112个可训练的参数组成,使得噪声去除过程非常简单。在滤波之后添加噪声图(NM)以保留高级特征。我们用10名患者的身体扫描数据训练JBFnet,并在AAPM低剂量CT Grand Challenge数据集上对其进行测试。我们将JBFnet与最先进的深度学习网络进行比较。JBFnet在去除噪声的同时保留结构方面优于测试数据集上的CPCE 3D,GAN和深度GFnet。我们进行了几次消融研究,以测试我们的网络架构和训练方法的性能。我们目前的设置实现了最佳性能,同时仍然保持行为问责制。
Ultra Low-Parameter Denoising: Trainable Bilateral Filter Layers in Computed Tomography
Friedrich-Alexander University Erlangen-Nürnberg(埃尔朗根-纽伦堡弗里德里希-亚历山大大学);Fraunhofer Institute for Ceramic Technologies and Systems IKTS(弗劳恩霍夫陶瓷技术与系统研究所(IKTS));Leibniz Institute for Analytical Sciences ISAS(莱布尼茨分析科学研究所(ISAS));University Hospital Erlangen(埃尔朗根大学医院);Institute for Nanotechnology and Correlative Microscopy e.V. INAM(纳米技术与关联显微镜协会研究所(INAM))
计算机断层扫描被广泛用作一种成像工具,以显示具有表达性骨-软组织对比度的三维结构。然而,CT分辨率和辐射剂量是紧密纠缠在一起的,突出了低剂量CT与复杂的去噪算法相结合的重要性。大多数数据驱动的去噪技术都基于深度神经网络,因此包含数十万个可训练的参数,这使得它们难以理解,并且容易出现预测失败。开发可理解且强大的去噪算法,实现最先进的性能,有助于在保持数据完整性的同时最大限度地减少辐射剂量。本文提出了一种基于双边滤波思想的开放源代码CT去噪框架。我们提出了一种双边滤波器,可以将其纳入深度学习管道,并通过计算其超参数及其输入的梯度流以纯粹的数据驱动方式进行优化。在纯图像到图像的管道和跨不同的域,如原始探测器数据和重建的体积,使用可微反投影层,去噪,证明。虽然每个滤波器层仅使用三个空间参数和一个范围参数,但所提出的去噪管道可以与具有数十万个参数的深度最先进的去噪架构竞争。在SSIM和PSNR方面,在X射线显微镜骨骼数据(0.7053和33.10)和2016年低剂量CT Grand Challenge数据集(0.9674和43.07)上实现了具有竞争力的去噪性能。由于具有明确效果的可训练参数数量极低,与大多数其他基于深度学习的去噪架构相比,在拟议的管道中随时保证预测可靠性和数据完整性。
A deep dictionary network-based foundation model for ultra-low-dose CT denoising
Yanshan University(燕山大学);Capital Medical University(首都医科大学);Beijing Friendship Hospital(北京友谊医院);Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences(中国科学院深圳先进技术研究院);Agency for Science, Technology and Research (A*STAR)(新加坡科技研究局)
FrequencyCT: Frequency Domain Self-supervised Low-dose CT Denoising
School of Information Engineering, Nanchang University(南昌大学信息工程学院);SKLMS, ICMSEC, Academy of Mathematics and Systems Science, Chinese Academy of Sciences(中国科学院数学与系统科学研究院SKLMS、ICMSEC)