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arXiv 2403.07971physics.soc-phmath.OCq-bio.PE
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评估COVID-19大流行期间疫苗犹豫对关键资源分配的影响

Evaluating the Impact of Vaccine Hesitancy on the Allocation of Vital Resources During COVID-19 Pandemic

Hieu Bui, Sandra Eksioglu, Ruben Proano

AI总结:

本研究改进SEIR模型纳入疫苗犹豫和资源可用性,模拟不同疫苗犹豫情景,发现减少疫苗犹豫和保障关键资源能显著降低死亡并遏制疫情传播。

摘要:

COVID-19大流行凸显了关键医疗资源分配中的重大挑战。现有的流行病学模型,特别是分区模型,旨在预测COVID-19病毒的传播及其对人口的影响,但忽略了疫苗犹豫(VH)对疾病动态的影响,包括预期的住院人数和死亡人数。我们提出对COVID-19的SEIR模型进行改进,纳入疫苗接种、疫苗犹豫(VH)和资源可用性对疾病动态的影响。我们收集公开可用的数据并进行数据分析,以捕捉疫苗犹豫(VH)随时间的动态变化,并为疫苗犹豫(VH)制定情景路径。我们针对每条疫苗犹豫(VH)路径模拟所提出的分区模型,以解释公众对疫苗接种态度的影响、医疗资源对患者结局的影响,以及疫苗接种推广时机对疫情进展和严重程度的影响。我们的分析表明,减少疫苗犹豫(VH)可改善健康结局,这强调了解决疫苗犹豫(VH)以遏制传染病传播的重要性。我们的结果显示,充足的關鍵医疗资源水平对于减少死亡至关重要,同时也强调了及时有效的疫苗接种计划在挽救生命方面的作用。

英文摘要:

The COVID-19 pandemic highlighted significant challenges in the allocation of vital healthcare resources. Existing epidemiological models, specifically compartmental models, aimed to predict the spread of the COVID-19 virus and its impact on the population, but they overlooked the influence of \ac{VH} on disease dynamics, including the expected number of hospitalizations and fatalities. We propose improvements to the \ac{SEIR} model for COVID-19 by incorporating the influence of vaccination, \ac{VH}, and resource availability on the disease dynamics. We collect publicly available data and perform data analysis to capture \ac{VH} dynamic changes over time and develop scenario paths for \ac{VH}. We simulate the proposed compartmental model for each \ac{VH} path to explain the impacts of public attitudes toward vaccination, the impacts of healthcare resources on patient outcomes, and the timing of vaccination rollout on the progression and severity of the epidemic. Our analysis demonstrates that reducing \ac{VH} improves health outcomes, reinforcing the importance of addressing \ac{VH} to curb the spread of infectious diseases. Our results show that adequate levels of critical healthcare resources are crucial for minimizing fatalities and also highlight the life-saving impact of timely and effective vaccination programs.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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