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arXiv 2201.12535eess.IVcs.AIphysics.med-ph
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欠采样 MRI 自监督图像重建方法的验证与泛化性

Validation and Generalizability of Self-Supervised Image Reconstruction Methods for Undersampled MRI

Center for Biomedical Imaging(生物医学成像中心);Siemens Healthineers International AG(西门子医疗国际公司);Lausanne University Hospital(洛桑大学医院);University of Lausanne(洛桑大学);sitem-insel;University of Bern(伯尔尼大学)
Thomas Yu, Tom Hilbert, Gian Franco Piredda, Arun Joseph, Gabriele Bonanno, Salim Zenkhri, Patrick Omoumi, Meritxell Bach Cuadra, Erick Jorge Canales-Rodríguez,… 展开作者

Thomas Yu, Tom Hilbert, Gian Franco Piredda, Arun Joseph, Gabriele Bonanno, Salim Zenkhri, Patrick Omoumi, Meritxell Bach Cuadra, Erick Jorge Canales-Rodríguez, Tobias Kober, Jean-Philippe Thiran

AI总结:

本文研究了欠采样MRI自监督重建算法的验证与泛化问题,发现前瞻性重建存在失真,感知指标优于逐像素指标,且泛化能力更受解剖结构变化影响。

摘要:

深度学习方法已成为欠采样 MR 重建的最先进技术。特别是在无法获取真值、全采样数据的情况下,用于重建的自监督机器学习方法正得到越来越广泛的应用。然而,此类方法在验证中的潜在问题及其泛化能力仍未被充分探索。本文研究了欠采样 MR 图像重建自监督算法验证的重要方面:前瞻性重建的定量评估、前瞻性与回顾性重建之间的潜在差异、常用定量指标的适用性以及泛化能力。研究了两种基于自监督去噪和深度图像先验的自监督算法。使用体内和体模数据,将这些方法与最小二乘拟合和压缩感知重建进行了比较。使用与训练条件不同的实验条件下的前瞻性欠采样数据测试了它们的泛化能力。我们表明,相对于回顾性重建/真值,前瞻性重建可能表现出显著失真。此外,与感知指标相比,逐像素定量指标可能无法准确捕捉感知质量的差异。另外,所有方法都展现出泛化潜力;然而,泛化能力受解剖结构/对比度变化的影响大于其他变化。我们进一步表明,无参考图像指标与用于研究泛化能力的人类图像质量评级高度一致。最后,我们表明,经过良好调优的压缩感知重建与学习去噪在所有数据上表现相似。

英文摘要:

Deep learning methods have become the state of the art for undersampled MR reconstruction. Particularly for cases where it is infeasible or impossible for ground truth, fully sampled data to be acquired, self-supervised machine learning methods for reconstruction are becoming increasingly used. However potential issues in the validation of such methods, as well as their generalizability, remain underexplored. In this paper, we investigate important aspects of the validation of self-supervised algorithms for reconstruction of undersampled MR images: quantitative evaluation of prospective reconstructions, potential differences between prospective and retrospective reconstructions, suitability of commonly used quantitative metrics, and generalizability. Two self-supervised algorithms based on self-supervised denoising and the deep image prior were investigated. These methods are compared to a least squares fitting and a compressed sensing reconstruction using in-vivo and phantom data. Their generalizability was tested with prospectively under-sampled data from experimental conditions different to the training. We show that prospective reconstructions can exhibit significant distortion relative to retrospective reconstructions/ground truth. Furthermore, pixel-wise quantitative metrics may not capture differences in perceptual quality accurately, in contrast to a perceptual metric. In addition, all methods showed potential for generalization; however, generalizability is more affected by changes in anatomy/contrast than other changes. We further showed that no-reference image metrics correspond well with human rating of image quality for studying generalizability. Finally, we showed that a well-tuned compressed sensing reconstruction and learned denoising perform similarly on all data.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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