In this paper, we develop an {\em epsilon admissible subsets} (EAS) model selection approach for performing group variable selection in the high-dimensional multivariate regression setting. This EAS strategy is designed to estimate a posterior-like, generalized fiducial distribution over a parsimonious class of models in the setting of correlated predictors and/or in the absence of a sparsity assumption. The effectiveness of our approach, to this end, is demonstrated empirically in simulation studies, and is compared to other state-of-the-art model/variable selection procedures. Furthermore, assuming a matrix-Normal linear model we show that the EAS strategy achieves {\em strong model selection consistency} in the high-dimensional setting if there does exist a sparse, true data generating set of predictors. In contrast to Bayesian approaches for model selection, our generalized fiducial approach completely avoids the problem of simultaneously having to specify arbitrary prior distributions for model parameters and penalize model complexity; our approach allows for inference directly on the model complexity. \textcolor{black}{Implementation of the method is illustrated through yeast data to identify significant cell-cycle regulating transcription factors.
Gaussian graphical models (GGMs) are well-established tools for probabilistic exploration of dependence structures using precision matrices. We develop a Bayesian method to incorporate covariate information in this GGMs setup in a nonlinear seemingly unrelated regression framework. We propose a joint predictor and graph selection model and develop an efficient collapsed Gibbs sampler algorithm to search the joint model space. Furthermore, we investigate its theoretical variable selection properties. We demonstrate our method on a variety of simulated data, concluding with a real data set from …
This article investigates unsupervised classification techniques for categorical multivariate data. The study employs multivariate multinomial mixture modeling, which is a type of model particularly applicable to multilocus genotypic data. A model selection procedure is used to simultaneously select the number of components and the relevant variables. A non-asymptotic oracle inequality is obtained, leading to the proposal of a new penalized maximum likelihood criterion. The selected model proves to be asymptotically consistent under weak assumptions on the true probability underlying the obser…
In this paper, we propose methods for functional predictor selection and the estimation of smooth functional coefficients simultaneously in a scalar-on-function regression problem under high-dimensional multivariate functional data setting. In particular, we develop two methods for functional group-sparse regression under a generic Hilbert space of infinite dimension. We show the convergence of algorithms and the consistency of the estimation and the selection (oracle property) under infinite-dimensional Hilbert spaces. Simulation studies show the effectiveness of the methods in both the selec…
We propose a novel and efficient iterative two-stage variable selection approach for multivariate sparse GLARMA models, which can be used for modelling multivariate discrete-valued time series. Our approach consists in iteratively combining two steps: the estimation of the autoregressive moving average (ARMA) coefficients of multivariate GLARMA models and the variable selection in the coefficients of the Generalized Linear Model (GLM) part of the model performed by regularized methods. We explain how to implement our approach efficiently. Then we assess the performance of our methodology using…
In this paper, we propose a novel variable selection approach in the framework of multivariate linear models taking into account the dependence that may exist between the responses. It consists in estimating beforehand the covariance matrix of the responses and to plug this estimator in a Lasso criterion, in order to obtain a sparse estimator of the coefficient matrix. The properties of our approach are investigated both from a theoretical and a numerical point of view. More precisely, we give general conditions that the estimators of the covariance matrix and its inverse have to satisfy in or…
In many practices, scientists are particularly interested in detecting which of the predictors are truly associated with a multivariate response. It is more accurate to model multiple responses as one vector rather than separating each component one by one. This is particularly true for complex traits having multiple correlated components. A Bayesian multivariate variable selection (BMVS) approach is proposed to select important predictors influencing the multivariate response from a candidate pool with an ultrahigh dimension. By applying the sample-size-dependent spike and slab priors, the BM…
We propose a method for detecting significant interactions in very large multivariate spatial point patterns. This methodology develops high dimensional data understanding in the point process setting. The method is based on modelling the patterns using a flexible Gibbs point process model to directly characterise point-to-point interactions at different spatial scales. By using the Gibbs framework significant interactions can also be captured at small scales. Subsequently, the Gibbs point process is fitted using a pseudo-likelihood approximation, and we select significant interactions automat…
We propose a Bayesian procedure for simultaneous variable and covariance selection using continuous spike-and-slab priors in multivariate linear regression models where q possibly correlated responses are regressed onto p predictors. Rather than relying on a stochastic search through the high-dimensional model space, we develop an ECM algorithm similar to the EMVS procedure of Rockova & George (2014) targeting modal estimates of the matrix of regression coefficients and residual precision matrix. Varying the scale of the continuous spike densities facilitates dynamic posterior exploration and …
In this paper we propose a computationally efficient algorithm for on-line variable selection in multivariate regression problems involving high dimensional data streams. The algorithm recursively extracts all the latent factors of a partial least squares solution and selects the most important variables for each factor. This is achieved by means of only one sparse singular value decomposition which can be efficiently updated on-line and in an adaptive fashion. Simulation results based on artificial data streams demonstrate that the algorithm is able to select important variables in dynamic se…
This article presents an approach to Bayesian semiparametric inference for Gaussian multivariate response regression. We are motivated by various small and medium dimensional problems from the physical and social sciences. The statistical challenges revolve around dealing with the unknown mean and variance functions and in particular, the correlation matrix. To tackle these problems, we have developed priors over the smooth functions and a Markov chain Monte Carlo algorithm for inference and model selection. Specifically, Dirichlet process mixtures of Gaussian distributions are used as the bas…
The modeling and analysis of degradation data have been an active research area in reliability and system health management. As the senor technology advances, multivariate sensory data are commonly collected for the underlying degradation process. However, most existing research on degradation modeling requires a univariate degradation index to be provided. Thus, constructing a degradation index for multivariate sensory data is a fundamental step in degradation modeling. In this paper, we propose a novel degradation index building method for multivariate sensory data. Based on an additive nonl…
We discuss Bayesian model uncertainty analysis and forecasting in sequential dynamic modeling of multivariate time series. The perspective is that of a decision-maker with a specific forecasting objective that guides thinking about relevant models. Based on formal Bayesian decision-theoretic reasoning, we develop a time-adaptive approach to exploring, weighting, combining and selecting models that differ in terms of predictive variables included. The adaptivity allows for changes in the sets of favored models over time, and is guided by the specific forecasting goals. A synthetic example illus…
We consider in this paper the multivariate regression problem, when the target regression matrix $A$ is close to a low rank matrix. Our primary interest in on the practical case where the variance of the noise is unknown. Our main contribution is to propose in this setting a criterion to select among a family of low rank estimators and prove a non-asymptotic oracle inequality for the resulting estimator. We also investigate the easier case where the variance of the noise is known and outline that the penalties appearing in our criterions are minimal (in some sense). These penalties involve the…
In this article, we study association between the structural connectome and cognitive profiles using a multi-response nonparametric regression model.The cognitive profiles are measured in terms of seven age-adjusted cognitive test scores. The structural connectomes are represented by undirected graphs. The connectivity properties of these graphs are available in terms of the nodal attributes. A collection of nodal centralities together can encode different patterns of connections in the brain network. In this article, we consider nine such attributes for each brain region.These nodal graph met…
We consider a multivariate finite mixture of Gaussian regression models for high-dimensional data, where the number of covariates and the size of the response may be much larger than the sample size. We provide an $\ell_1$-oracle inequality satisfied by the Lasso estimator according to the Kullback-Leibler loss. This result is an extension of the $\ell_1$-oracle inequality established by Meynet in \cite{Meynet} in the multivariate case. We focus on the Lasso for its $\ell_1$-regularization properties rather than for the variable selection procedure, as it was done in Städler in \cite{Stadler}.
Microorganisms play critical roles in human health and disease. It is well known that microbes live in diverse communities in which they interact synergistically or antagonistically. Thus for estimating microbial associations with clinical covariates, multivariate statistical models are preferred. Multivariate models allow one to estimate and exploit complex interdependencies among multiple taxa, yielding more powerful tests of exposure or treatment effects than application of taxon-specific univariate analyses. In addition, the analysis of microbial count data requires special attention becau…
We provide finite sample properties of sparse multivariate ARCH processes, where the linear representation of ARCH models allows for an ordinary least squares estimation. Under the restricted strong convexity of the unpenalized loss function, regularity conditions on the penalty function, strict stationary and beta-mixing process, we prove non-asymptotic error bounds on the regularized ARCH estimator. Based on the primal-dual witness method of Loh and Wainwright (2017), we establish variable selection consistency, including the case when the penalty function is non-convex. These theoretical re…
Omic data are characterized by the presence of strong dependence structures that result either from data acquisition or from some underlying biological processes. In metabolomics, for instance, data resulting from Liquid Chromatography-Mass Spectrometry (LC-MS) -- a technique which gives access to a large coverage of metabolites -- exhibit such patterns. These data sets are typically used to find the metabolites characterizing a phenotype of interest associated with the samples. However, applying some statistical procedures that do not adjust the variable selection step to the dependence patte…
A novel approach for estimating functions in the multivariate setting based on an adaptive knot selection for B-splines with an application to a chemical system used in geoscience
提出利用 generalized lasso 自适应选择 B 样条节点并结合 EBIC 的多元非参数回归估计方法，实验表明其稳健且优于现有方法，并以 glober R 包发布。
Florida State University（佛罗里达州立大学）；Peking University（北京大学）
Modern high-dimensional methods often adopt the "bet on sparsity" principle, while in supervised multivariate learning statisticians may face "dense" problems with a large number of nonzero coefficients. This paper proposes a novel clustered reduced-rank learning (CRL) framework that imposes two joint matrix regularizations to automatically group the features in constructing predictive factors. CRL is more interpretable than low-rank modeling and relaxes the stringent sparsity assumption in variable selection. In this paper, new information-theoretical limits are presented to reveal the intrin…
Tropical cyclone and sea surface temperature data have been used in several studies to forecast the total number of hurricanes in the Atlantic Basin. Sea surface temperature (SST) and latent heat flux (LHF) are correlated with tropical cyclone occurrences, but this correlation is known to vary with location and strength of the storm. The objective of this article is to identify features of SST and LHF that can explain the spatial-temporal variation of tropical cyclone counts, categorized by their strength. We develop a variable selection procedure for multivariate spatial-temporally varying co…
The method of generalized estimating equations (GEE) is popular in the biostatistics literature for analyzing longitudinal binary and count data. It assumes a generalized linear model (GLM) for the outcome variable, and a working correlation among repeated measurements. In this paper, we introduce a viable competitor: the weighted scores method for GLM margins. We weight the univariate score equations using a working discretized multivariate normal model that is a proper multivariate model. Since the weighted scores method is a parametric method based on likelihood, we propose composite likeli…
Hotelling's $T^2$-test for the mean of a multivariate normal distribution is one of the triumphs of classical multivariate analysis. It is uniformly most powerful among invariant tests, and admissible, proper Bayes, and locally and asymptotically minimax among all tests. Nonetheless, investigators often prefer non-invariant tests, especially those obtained by selecting only a small subset of variables from which the $T^2$-statistic is to be calculated, because such reduced statistics are more easily interpretable for their specific application. Thus it is relevant to ask the extent to which po…
Modeling data with multivariate count responses is a challenging problem due to the discrete nature of the responses. Existing methods for univariate count responses cannot be easily extended to the multivariate case since the dependency among multiple responses needs to be properly accommodated. In this paper, we propose a multivariate Poisson log-normal regression model for multivariate data with count responses. By simultaneously estimating the regression coefficients and inverse covariance matrix over the latent variables with an efficient Monte Carlo EM algorithm, the proposed regression …
Data transformation, e.g. feature transformation and selection, is an integral part of any machine learning procedure. In this paper we introduce an information-theoretic model and tools to assess the quality of data transformations in machine learning tasks. In an unsupervised fashion, we analyze the transfer of information of the transformation of a discrete, multivariate source of information X into a discrete, multivariate sink of information Y related by a distribution PXY . The first contribution is a decomposition of the maximal potential entropy of (X, Y) that we call a balance equatio…
Multivariate regression model is a natural generalization of the classical univari- ate regression model for fitting multiple responses. In this paper, we propose a high- dimensional multivariate conditional regression model for constructing sparse estimates of the multivariate regression coefficient matrix that accounts for the dependency struc- ture among the multiple responses. The proposed method decomposes the multivariate regression problem into a series of penalized conditional log-likelihood of each response conditioned on the covariates and other responses. It allows simultaneous esti…
High-dimensional classification has become an increasingly important problem. In this paper we propose a "Multivariate Adaptive Stochastic Search" (MASS) approach which first reduces the dimension of the data space and then applies a standard classification method to the reduced space. One key advantage of MASS is that it automatically adjusts to mimic variable selection type methods, such as the Lasso, variable combination methods, such as PCA, or methods that combine these two approaches. The adaptivity of MASS allows it to perform well in situations where pure variable selection or variable…
Kernel density estimation is a well known method involving a smoothing parameter (the bandwidth) that needs to be tuned by the user. Although this method has been widely used the bandwidth selection remains a challenging issue in terms of balancing algorithmic performance and statistical relevance. The purpose of this paper is to compare a recently developped bandwidth selection method for kernel density estimation to those which are commonly used by now (at least those which are implemented in the R-package). This new method is called Penalized Comparison to Overfitting (PCO). It has been pro…
We present a common framework for Bayesian emulation methodologies for multivariate-output simulators, or computer models, that employ either parametric linear models or nonparametric Gaussian processes. Novel diagnostics suitable for multivariate covariance-separable emulators are developed and techniques to improve the adequacy of an emulator are discussed and implemented. A variety of emulators are compared for a humanitarian relief simulator, modelling aid missions to Sicily after a volcanic eruption and earthquake, and a sensitivity analysis is conducted to determine the sensitivity of th…
Recent work on fractionally-supervised classification (FSC), an approach that allows classification to be carried out with a fractional amount of weight given to the unlabelled points, is further developed in two respects. The primary development addresses a question of fundamental importance over how to choose the amount of weight given to the unlabelled points. The resolution of this matter is essential because it makes FSC more readily applicable to real problems. Interestingly, the resolution of the weight selection problem opens up the possibility of a different approach to model selectio…
The multivariate normal linear model is one of the most widely employed models for statistical inference in applied research. Special cases include (multivariate) t testing, (M)AN(C)OVA, (multivariate) multiple regression, and repeated measures analysis. Statistical procedures for model selection where the models may have equality and order constraints on the model parameters of interest are limited however. This paper presents a default Bayes factor for this model selection problem. The default Bayes factor is based on generalized fractional Bayes methodology where different fractions are use…
Selection of covariates is crucial in the estimation of average treatment effects given observational data with high or even ultra-high dimensional pretreatment variables. Existing methods for this problem typically assume sparse linear models for both outcome and univariate treatment, and cannot handle situations with ultra-high dimensional covariates. In this paper, we propose a new covariate selection strategy called double screening prior adaptive lasso (DSPAL) to select confounders and predictors of the outcome for multivariate treatments, which combines the adaptive lasso method with the…
Regular vine copulas can describe a wider array of dependency patterns than the multivariate Gaussian copula or the multivariate Student's t copula. This paper presents two contributions related to model selection of regular vine copulas. First, our pair copula family selection procedure extends existing Bayesian family selection methods by allowing pair families to be chosen from an arbitrary set of candidate families. Second, our method represents the first Bayesian model selection approach to include the regular vine density construction in its scope of inference. The merits of our approach…
We consider bandwidth matrix selection for kernel density estimators (KDEs) of density level sets in $\mathbb{R}^d$, $d \ge 2$. We also consider estimation of highest density regions, which differs from estimating level sets in that one specifies the probability content of the set rather than specifying the level directly. This complicates the problem. Bandwidth selection for KDEs is well studied, but the goal of most methods is to minimize a global loss function for the density or its derivatives. The loss we consider here is instead the measure of the symmetric difference of the true set and…
The Misspecification-Resistant Information Criterion (MRIC) proposed in [H.-L. Hsu, C.-K. Ing, H. Tong: On model selection from a finite family of possibly misspecified time series models. The Annals of Statistics. 47 (2), 1061--1087 (2019)] is a model selection criterion for univariate parametric time series that enjoys both the property of consistency and asymptotic efficiency. In this article we extend the MRIC to the case where the response is a multivariate time series and the predictor is univariate. The extension requires novel derivations based upon random matrix theory. We obtain an a…
In molecular biology, advances in high-throughput technologies have made it possible to study complex multivariate phenotypes and their simultaneous associations with high-dimensional genomic and other omics data, a problem that can be studied with high-dimensional multi-response regression, where the response variables are potentially highly correlated. To this purpose, we recently introduced several multivariate Bayesian variable and covariance selection models, e.g., Bayesian estimation methods for sparse seemingly unrelated regression for variable and covariance selection. Several variable…
We propose a novel personalized concept for the optimal treatment selection for a situation where the response is a multivariate vector, that could contain right-censored variables such as survival time. The proposed method can be applied with any number of treatments and outcome variables, under a broad set of models. Following a working semiparametric Single Index Model that relates covariates and responses, we first define a patient-specific composite score, constructed from individual covariates. We then estimate conditional means of each response, given the patient score, correspond to ea…
High-dimensional tests are applied to find relevant sets of variables and relevant models. If variables are selected by analyzing the sums of products matrices and a corresponding mean-value test is performed, there is the danger that the nominal error of first kind is exceeded. In the paper, well-known multivariate tests receive a new mathematical interpretation such that the error of first kind of the combined testing and selecting procedure can more easily be kept. The null hypotheses on mean values are replaced by hypotheses on distributional sphericity of the individual score responses. T…
