Resting state functional magnetic resonance images (fMRI) are commonly used for classification of patients as having Alzheimer's disease (AD), mild cognitive impairment (MCI), or being cognitive normal (CN). Most methods use time-series correlation of voxels signals during the observation period as a basis for the classification. In this paper we show that Convolutional Neural Network (CNN) classification based on spatial correlation of time-averaged signals yield a classification accuracy of up to 82% (sensitivity 86%, specificity 80%)for a data set with 429 subjects (246 cognitive normal and 183 Alzheimer patients). For the spatial correlation of time-averaged signal values we use voxel subdomains around center points of the 90 regions AAL atlas. We form the subdomains as sets of voxels along a Hilbert curve of a bounding box in which the brain is embedded with the AAL regions center points serving as subdomain seeds. The matrix resulting from the spatial correlation of the 90 arrays formed by the subdomain segments of the Hilbert curve yields a symmetric 90x90 matrix that is used for the classification based on two different CNN networks, a 4-layer CNN network with 3x3 filters and with 4, 8, 16, and 32 output channels respectively, and a 2-layer CNN network with 3x3 filters and with 4 and 8 output channels respectively. The results of the two networks are reported and compared.
Semmelhack et al. (2014) have achieved high classification accuracy in distinguishing swim bouts of zebrafish using a Support Vector Machine (SVM). Convolutional Neural Networks (CNNs) have reached superior performance in various image recognition tasks over SVMs, but these powerful networks remain a black box. Reaching better transparency helps to build trust in their classifications and makes learned features interpretable to experts. Using a recently developed technique called Deep Taylor Decomposition, we generated heatmaps to highlight input regions of high relevance for predictions. We f…
Hyperspectral Image (HSI) classification using Convolutional Neural Networks (CNN) is widely found in the current literature. Approaches vary from using SVMs to 2D CNNs, 3D CNNs, 3D-2D CNNs. Besides 3D-2D CNNs and FuSENet, the other approaches do not consider both the spectral and spatial features together for HSI classification task, thereby resulting in poor performances. 3D CNNs are computationally heavy and are not widely used, while 2D CNNs do not consider multi-resolution processing of images, and only limits itself to the spatial features. Even though 3D-2D CNNs try to model the spectra…
This work proposes an algorithm for fMRI data analysis for the classification of ADHD disorders. There have been several breakthroughs in the analysis of fMRI via 3D convolutional neural networks (CNNs). With these new techniques it is possible to preserve the 3D spatial data of fMRI data. Additionally there have been recent advances in the use of 3D generative adversarial neural networks (GANs) for the generation of normal MRI data. This work utilizes multi modal 3D CNNs with data augmentation from 3D GAN for ADHD prediction from fMRI. By leveraging a 3D-GAN it would be possible to use deepfa…
Nanjing University of Information Science and Technology（南京信息工程大学）；University of Missouri-Kansas City（密苏里大学堪萨斯城分校）；Helmholtz-Zentrum Dresden-Rossendorf（亥姆霍兹德累斯顿罗森多夫研究中心）；Helmholtz Institute Freiberg for Resource Technology（亥姆霍兹弗赖贝格资源技术研究所）；University of Maryland, College Park（马里兰大学帕克分校）
Convolutional neural networks (CNNs) have been widely used for hyperspectral image classification. As a common process, small cubes are firstly cropped from the hyperspectral image and then fed into CNNs to extract spectral and spatial features. It is well known that different spectral bands and spatial positions in the cubes have different discriminative abilities. If fully explored, this prior information will help improve the learning capacity of CNNs. Along this direction, we propose an attention aided CNN model for spectral-spatial classification of hyperspectral images. Specifically, a s…
Institute of Technology, University of Kashmir（克什米尔大学技术学院）
One-class CNNs have shown promise in novelty detection. However, very less work has been done on extending them to multiclass classification. The proposed approach is a viable effort in this direction. It uses one-class CNNs i.e., it trains one CNN per class, for multiclass classification. An ensemble of such one-class CNNs is used for multiclass classification. The benefits of the approach are generally better recognition accuracy while taking almost even half or two-thirds of the training time of a conventional multi-class deep network. The proposed approach has been applied successfully to …
In this paper we challenge the common assumption that convolutional layers in modern CNNs are translation invariant. We show that CNNs can and will exploit the absolute spatial location by learning filters that respond exclusively to particular absolute locations by exploiting image boundary effects. Because modern CNNs filters have a huge receptive field, these boundary effects operate even far from the image boundary, allowing the network to exploit absolute spatial location all over the image. We give a simple solution to remove spatial location encoding which improves translation invarianc…
Malaria is a deadly disease which claims the lives of hundreds of thousands of people every year. Computational methods have been proven to be useful in the medical industry by providing effective means of classification of diagnostic imaging and disease identification. This paper examines different machine learning methods in the context of classifying the presence of malaria in cell images. Numerous machine learning methods can be applied to the same problem; the question of whether one machine learning method is better suited to a problem relies heavily on the problem itself and the impleme…
University of Maryland Baltimore County（马里兰大学巴尔的摩县分校）
We present a hybrid algorithm to estimate lung nodule malignancy that combines imaging biomarkers from Radiologist's annotation with image classification of CT scans. Our algorithm employs a 3D Convolutional Neural Network (CNN) as well as a Random Forest in order to combine CT imagery with biomarker annotation and volumetric radiomic features. We analyze and compare the performance of the algorithm using only imagery, only biomarkers, combined imagery + biomarkers, combined imagery + volumetric radiomic features and finally the combination of imagery + biomarkers + volumetric features in orde…
School of Informatics, University of Edinburgh（爱丁堡大学信息学院）
Convolutional Neural Networks, or CNNs, are the state of the art for image classification, but typically come at the cost of a large memory footprint. This limits their usefulness in applications relying on embedded devices, where memory is often a scarce resource. Recently, there has been significant progress in the field of image classification on such memory-constrained devices, with novel contributions like the ProtoNN, Bonsai and FastGRNN algorithms. These have been shown to reach up to 98.2% accuracy on optical character recognition using MNIST-10, with a memory footprint as little as 6K…
Technical University of Munich（慕尼黑工业大学）；Eskisehir Osmangazi University（埃斯基谢希尔奥桑加齐大学）
Convolutional Neural Networks with 3D kernels (3D-CNNs) currently achieve state-of-the-art results in video recognition tasks due to their supremacy in extracting spatiotemporal features within video frames. There have been many successful 3D-CNN architectures surpassing the state-of-the-art results successively. However, nearly all of them are designed to operate offline creating several serious handicaps during online operation. Firstly, conventional 3D-CNNs are not dynamic since their output features represent the complete input clip instead of the most recent frame in the clip. Secondly, t…
COVID-19 pandemic continues to spread rapidly over the world and causes a tremendous crisis in global human health and the economy. Its early detection and diagnosis are crucial for controlling the further spread. Many deep learning-based methods have been proposed to assist clinicians in automatic COVID-19 diagnosis based on computed tomography imaging. However, challenges still remain, including low data diversity in existing datasets, and unsatisfied detection resulting from insufficient accuracy and sensitivity of deep learning models. To enhance the data diversity, we design augmentation …
We propose a feature generator backbone composed of an ensemble of convolutional neuralnetworks (CNNs) to improve the recently emerging Vision Transformer (ViT) models. We tackled the RSNA intracranial hemorrhage classification problem, i.e., identifying various hemorrhage types from computed tomography (CT) slices. We show that by gradually stacking several feature maps extracted using multiple Xception CNNs, we can develop a feature-rich input for the ViT model. Our approach allowed the ViT model to pay attention to relevant features at multiple levels. Moreover, pretraining the n CNNs using…
Universitat Pompeu Fabra（庞培法布拉大学）；University of Adelaide（阿德莱德大学）；ICREA（加泰罗尼亚研究与创新高级研究所）
This paper compares well-established Convolutional Neural Networks (CNNs) to recently introduced Vision Transformers for the task of Diabetic Foot Ulcer Classification, in the context of the DFUC 2021 Grand-Challenge, in which this work attained the first position. Comprehensive experiments demonstrate that modern CNNs are still capable of outperforming Transformers in a low-data regime, likely owing to their ability for better exploiting spatial correlations. In addition, we empirically demonstrate that the recent Sharpness-Aware Minimization (SAM) optimization algorithm considerably improves…
Politecnico di Milano（米兰理工大学）；Istituto Italiano di Tecnologia（意大利技术研究院）；Università Politecnica delle Marche（马尔凯理工大学）
Breast cancer is one of the deadliest cancer worldwide. Timely detection could reduce mortality rates. In the clinical routine, classifying benign and malignant tumors from ultrasound (US) imaging is a crucial but challenging task. An automated method, which can deal with the variability of data is therefore needed. In this paper, we compared different Convolutional Neural Networks (CNNs) and transfer learning methods for the task of automated breast tumor classification. The architectures investigated in this study were VGG-16 and Inception V3. Two different training strategies were investiga…
Convolutional Neural Networks (CNNs) have proved very accurate in multiple computer vision image classification tasks that required visual inspection in the past (e.g., object recognition, face detection, etc.). Motivated by these astonishing results, researchers have also started using CNNs to cope with image forensic problems (e.g., camera model identification, tampering detection, etc.). However, in computer vision, image classification methods typically rely on visual cues easily detectable by human eyes. Conversely, forensic solutions rely on almost invisible traces that are often very su…
Skolkovo Institute of Science and Technology（斯科尔科沃科学技术研究院）
Deep learning shows high potential for many medical image analysis tasks. Neural networks can work with full-size data without extensive preprocessing and feature generation and, thus, information loss. Recent work has shown that the morphological difference in specific brain regions can be found on MRI with the means of Convolution Neural Networks (CNN). However, interpretation of the existing models is based on a region of interest and can not be extended to voxel-wise image interpretation on a whole image. In the current work, we consider the classification task on a large-scale open-source…
Nanjing University of Information Science and Technology（南京信息工程大学）；University of Missouri-Kansas City（密苏里大学堪萨斯城分校）；Helmholtz-Zentrum Dresden-Rossendorf（德累斯顿-罗森多夫亥姆霍兹中心）；Helmholtz Institute Freiberg for Resource Technology（弗赖贝格资源技术亥姆霍兹研究所）；German Aerospace Center（德国航空航天中心）；Technical University of Munich（慕尼黑工业大学）
In this paper, we propose an efficient and effective framework to fuse hyperspectral and Light Detection And Ranging (LiDAR) data using two coupled convolutional neural networks (CNNs). One CNN is designed to learn spectral-spatial features from hyperspectral data, and the other one is used to capture the elevation information from LiDAR data. Both of them consist of three convolutional layers, and the last two convolutional layers are coupled together via a parameter sharing strategy. In the fusion phase, feature-level and decision-level fusion methods are simultaneously used to integrate the…
From Modern CNNs to Vision Transformers: Assessing the Performance, Robustness, and Classification Strategies of Deep Learning Models in Histopathology
Fraunhofer Heinrich Hertz Institute（弗劳恩霍夫海因里希·赫兹研究所）；University of Oldenburg（奥尔登堡大学）
Convolutional Neural Networks (CNNs) have revolutionized performances in several machine learning tasks such as image classification, object tracking, and keyword spotting. However, given that they contain a large number of parameters, their direct applicability into low resource tasks is not straightforward. In this work, we experiment with an application of CNN models to gastrointestinal landmark classification with only a few thousands of training samples through transfer learning. As in a standard transfer learning approach, we train CNNs on a large external corpus, followed by representat…
Background: Functional magnetic resonance imaging (fMRI) provides non-invasive measures of neuronal activity using an endogenous Blood Oxygenation-Level Dependent (BOLD) contrast. This article introduces a nonlinear dimensionality reduction (Locally Linear Embedding) to extract informative measures of the underlying neuronal activity from BOLD time-series. The method is validated using the Leave-One-Out-Cross-Validation (LOOCV) accuracy of classifying psychiatric diagnoses using resting-state and task-related fMRI. Methods: Locally Linear Embedding of BOLD time-series (into each voxel's respec…
