arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 2006.15969q-bio.NCcs.CVcs.LGeess.IVstat.ML
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用于脑MRI数据分类的3D CNN解释

Interpretation of 3D CNNs for Brain MRI Data Classification

Skolkovo Institute of Science and Technology(斯科尔科沃科学技术研究院)

Maxim Kan, Ruslan Aliev, Anna Rudenko, Nikita Drobyshev, Nikita Petrashen, Ekaterina Kondrateva, Maxim Sharaev, Alexander Bernstein, Evgeny Burnaev

摘要:

深度学习在许多医学图像分析任务中显示出很高的潜力。神经网络可以处理全尺寸数据,而无需大量的预处理和特征生成,因此不会丢失信息。最近的研究表明,利用卷积神经网络(CNN)可以在MRI上发现特定脑区的形态差异。然而,现有模型的解释是基于感兴趣的区域,不能扩展到整个图像上的体素图像解释。在目前的工作中,我们考虑了年轻健康受试者的大规模开源数据集的分类任务-探索男性和女性之间的大脑差异。在本文中,我们扩展了以前的研究结果在性别差异的扩散张量成像T1脑MRI扫描。我们提供了逐体素的3D CNN解释,比较了三种解释方法的结果:有意义的扰动,Grad CAM和引导反向传播,并与开源库一起贡献。

英文摘要:

Deep learning shows high potential for many medical image analysis tasks. Neural networks can work with full-size data without extensive preprocessing and feature generation and, thus, information loss. Recent work has shown that the morphological difference in specific brain regions can be found on MRI with the means of Convolution Neural Networks (CNN). However, interpretation of the existing models is based on a region of interest and can not be extended to voxel-wise image interpretation on a whole image. In the current work, we consider the classification task on a large-scale open-source dataset of young healthy subjects -- an exploration of brain differences between men and women. In this paper, we extend the previous findings in gender differences from diffusion-tensor imaging on T1 brain MRI scans. We provide the voxel-wise 3D CNN interpretation comparing the results of three interpretation methods: Meaningful Perturbations, Grad CAM and Guided Backpropagation, and contribute with the open-source library.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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