To extract liver from medical images is a challenging task due to similar intensity values of liver with adjacent organs, various contrast levels, various noise associated with medical images and irregular shape of liver. To address these issues, it is important to preprocess the medical images, i.e., computerized tomography (CT) and magnetic resonance imaging (MRI) data prior to liver analysis and quantification. This paper investigates the impact of permutation of various preprocessing techniques for CT images, on the automated liver segmentation using deep learning, i.e., U-Net architecture. The study focuses on Hounsfield Unit (HU) windowing, contrast limited adaptive histogram equalization (CLAHE), z-score normalization, median filtering and Block-Matching and 3D (BM3D) filtering. The segmented results show that combination of three techniques; HU-windowing, median filtering and z-score normalization achieve optimal performance with Dice coefficient of 96.93%, 90.77% and 90.84% for training, validation and testing respectively.
National Institutes of Health Clinical Center（美国国立卫生研究院临床中心）；Ping An Insurance Company of China（中国平安保险公司）
Developing an effective liver and liver tumor segmentation model from CT scans is very important for the success of liver cancer diagnosis, surgical planning and cancer treatment. In this work, we propose a two-stage framework for 2D liver and tumor segmentation. The first stage is a coarse liver segmentation network, while the second stage is an edge enhanced network (E$^2$Net) for more accurate liver and tumor segmentation. E$^2$Net explicitly models complementary objects (liver and tumor) and their edge information within the network to preserve the organ and lesion boundaries. We introduce…
Label-Efficient Cross-Modality Generalization for Liver Segmentation in Multi-Phase MRI
Ho Chi Minh University of Science（胡志明科技大学）；National Central University（国立中央大学）；Carnegie Mellon University（卡内基梅隆大学）；University of Houston（休斯顿大学）；Northwestern University（西北大学）
Accurate segmentation of the liver is a prerequisite for the diagnosis of disease. Automated segmentation is an important application of computer-aided detection and diagnosis of liver disease. In recent years, automated processing of medical images has gained breakthroughs. However, the low contrast of abdominal scan CT images and the complexity of liver morphology make accurate automatic segmentation challenging. In this paper, we propose RA V-Net, which is an improved medical image automatic segmentation model based on U-Net. It has the following three main innovations. CofRes Module (Compo…
The UK Biobank Imaging Study has acquired medical scans of more than 40,000 volunteer participants. The resulting wealth of anatomical information has been made available for research, together with extensive metadata including measurements of liver fat. These values play an important role in metabolic disease, but are only available for a minority of imaged subjects as their collection requires the careful work of image analysts on dedicated liver MRI. Another UK Biobank protocol is neck-to-knee body MRI for analysis of body composition. The resulting volumes can also quantify fat fractions, …
Otto-von-Guericke University（奥托·冯·格里克大学）；University Hospital of Magdeburg（马格德堡大学医院）
Deep learning-based segmentation of the liver and hepatic lesions therein steadily gains relevance in clinical practice due to the increasing incidence of liver cancer each year. Whereas various network variants with overall promising results in the field of medical image segmentation have been successfully developed over the last years, almost all of them struggle with the challenge of accurately segmenting hepatic lesions in magnetic resonance imaging (MRI). This led to the idea of combining elements of convolutional and transformer-based architectures to overcome the existing limitations. T…
Rongcheng College, Harbin University of Science and Technology（哈尔滨理工大学荣成学院）；Harbin University of Science and Technology（哈尔滨理工大学）；Hunan University of Technology and Business（湖南工商大学）
Background and objective: In this paper, a modified U-Net based framework is presented, which leverages techniques from Squeeze-and-Excitation (SE) block, Atrous Spatial Pyramid Pooling (ASPP) and residual learning for accurate and robust liver CT segmentation, and the effectiveness of the proposed method was tested on two public datasets LiTS17 and SLiver07. Methods: A new network architecture called SAR-U-Net was designed. Firstly, the SE block is introduced to adaptively extract image features after each convolution in the U-Net encoder, while suppressing irrelevant regions, and highlightin…
Mansoura University（曼苏尔大学）；South Valley University（南河谷大学）；Higher Institute of Engineering and Technology（高等工程技术学院）
The liver is one of the most critical metabolic organs in vertebrates due to its vital functions in the human body, such as detoxification of the blood from waste products and medications. Liver diseases due to liver tumors are one of the most common mortality reasons around the globe. Hence, detecting liver tumors in the early stages of tumor development is highly required as a critical part of medical treatment. Many imaging modalities can be used as aiding tools to detect liver tumors. Computed tomography (CT) is the most used imaging modality for soft tissue organs such as the liver. This …
Accurate visualization of liver tumors and their surrounding blood vessels is essential for noninvasive diagnosis and prognosis prediction of tumors. In medical image segmentation, there is still a lack of in-depth research on the simultaneous segmentation of liver tumors and peritumoral blood vessels. To this end, we collect the first liver tumor, and vessel segmentation benchmark datasets containing 52 portal vein phase computed tomography images with liver, liver tumor, and vessel annotations. In this case, we propose a 3D U-shaped Cross-Attention Network (UCA-Net) that utilizes a tailored …
Image Sciences Institute, University Medical Center Utrecht（乌得勒支大学医学中心图像科学研究所）；Department of Biomedical Engineering, Eindhoven University of Technology（埃因霍温理工大学生物医学工程系）
Despite the successes of deep learning techniques at detecting objects in medical images, false positive detections occur which may hinder an accurate diagnosis. We propose a technique to reduce false positive detections made by a neural network using an SVM classifier trained with features derived from the uncertainty map of the neural network prediction. We demonstrate the effectiveness of this method for the detection of liver lesions on a dataset of abdominal MR images. We find that the use of a dropout rate of 0.5 produces the least number of false positives in the neural network predicti…
Transfer learning and joint learning approaches are extensively used to improve the performance of Convolutional Neural Networks (CNNs). In medical imaging applications in which the target dataset is typically very small, transfer learning improves feature learning while joint learning has shown effectiveness in improving the network's generalization and robustness. In this work, we study the combination of these two approaches for the problem of liver lesion segmentation and classification. For this purpose, 332 abdominal CT slices containing lesion segmentation and classification of three le…
Purpose: To improve the quality of images obtained via dynamic contrast-enhanced MRI (DCE-MRI) that include motion artifacts and blurring using a deep learning approach. Methods: A multi-channel convolutional neural network (MARC) based method is proposed for reducing the motion artifacts and blurring caused by respiratory motion in images obtained via DCE-MRI of the liver. The training datasets for the neural network included images with and without respiration-induced motion artifacts or blurring, and the distortions were generated by simulating the phase error in k-space. Patient studies we…
Automatic segmentation of liver tumors in medical images is crucial for the computer-aided diagnosis and therapy. It is a challenging task, since the tumors are notoriously small against the background voxels. This paper proposes a new three-stage curriculum learning approach for training deep networks to tackle this small object segmentation problem. The learning in the first stage is performed on the whole input to obtain an initial deep network for tumor segmenta-tion. Then the second stage of learning focuses the strength-ening of tumor specific features by continuing training the network …
Automatic segmentation of medical images is among most demanded works in the medical information field since it saves time of the experts in the field and avoids human error factors. In this work, a method based on Conditional Adversarial Networks and Fully Convolutional Networks is proposed for the automatic segmentation of the liver MRIs. The proposed method, without any post-processing, is achieved the second place in the SIU Liver Segmentation Challenge 2018, data of which is provided by Dokuz Eylül University. In this paper, some improvements for the post-processing step are also proposed…
Colorectal liver metastasis is one of most aggressive liver malignancies. While the definition of lesion type based on CT images determines the diagnosis and therapeutic strategy, the discrimination between cancerous and non-cancerous lesions are critical and requires highly skilled expertise, experience and time. In the present work we introduce an end-to-end deep learning approach to assist in the discrimination between liver metastases from colorectal cancer and benign cysts in abdominal CT images of the liver. Our approach incorporates the efficient feature extraction of InceptionV3 combin…
Technical University of Munich（慕尼黑工业大学）；LMU Hospital Grosshadern（路德维希-马克西米利安-慕尼黑大学格罗斯哈德恩医院）
Automatic segmentation of the liver and hepatic lesions is an important step towards deriving quantitative biomarkers for accurate clinical diagnosis and computer-aided decision support systems. This paper presents a method to automatically segment liver and lesions in CT and MRI abdomen images using cascaded fully convolutional neural networks (CFCNs) enabling the segmentation of a large-scale medical trial or quantitative image analysis. We train and cascade two FCNs for a combined segmentation of the liver and its lesions. In the first step, we train a FCN to segment the liver as ROI input …
Automatic liver segmentation in 3D medical images is essential in many clinical applications, such as pathological diagnosis of hepatic diseases, surgical planning, and postoperative assessment. However, it is still a very challenging task due to the complex background, fuzzy boundary, and various appearance of liver. In this paper, we propose an automatic and efficient algorithm to segment liver from 3D CT volumes. A deep image-to-image network (DI2IN) is first deployed to generate the liver segmentation, employing a convolutional encoder-decoder architecture combined with multi-level feature…
Surgical resections are the most prevalent curative treatment for primary liver cancer. Tumors located in critical positions are known to complexify liver resections (LR). While experienced surgeons in specialized medical centers may have the necessary expertise to accurately anticipate LR complexity, and prepare accordingly, an objective method able to reproduce this behavior would have the potential to improve the standard routine of care, and avoid intra- and postoperative complications. In this article, we propose CoRe, an automated medical image processing pipeline for the prediction of p…
Center for Image Sciences, University Medical Center Utrecht（乌得勒支大学医学中心影像科学中心）
Most MRI liver segmentation methods use a structural 3D scan as input, such as a T1 or T2 weighted scan. Segmentation performance may be improved by utilizing both structural and functional information, as contained in dynamic contrast enhanced (DCE) MR series. Dynamic information can be incorporated in a segmentation method based on convolutional neural networks in a number of ways. In this study, the optimal input configuration of DCE MR images for convolutional neural networks (CNNs) is studied. The performance of three different input configurations for CNNs is studied for a liver segmenta…
Enhanced Liver Tumor Detection in CT Images Using 3D U-Net and Bat Algorithm for Hyperparameter Optimization
Department of Mathematics and Statistics, Loyola University Chicago（洛约拉大学芝加哥分校数学与统计学系）；Department of Mathematics and Computer Science, Islamic Azad University, Science and Research Branch（伊斯兰 Azad 大学科学与研究分校数学与计算机科学系）
本文提出将 3D U-Net 架构与 Bat Algorithm 结合，通过优化学习率和批大小等超参数实现 CT 图像中肝肿瘤的自动分割，有效提升了分割精度与鲁棒性。
Automatic extraction of liver and tumor from CT volumes is a challenging task due to their heterogeneous and diffusive shapes. Recently, 2D and 3D deep convolutional neural networks have become popular in medical image segmentation tasks because of the utilization of large labeled datasets to learn hierarchical features. However, 3D networks have some drawbacks due to their high cost on computational resources. In this paper, we propose a 3D hybrid residual attention-aware segmentation method, named RA-UNet, to precisely extract the liver volume of interests (VOI) and segment tumors from the l…
Barcelona Supercomputing Center (BSC)（巴塞罗那超级计算中心）；Eidgenössische Technische Hochschule Zürich (ETH Zürich)（苏黎世联邦理工学院）；Universitat Politècnica de Catalunya (UPC)（加泰罗尼亚理工大学）
A fully automatic technique for segmenting the liver and localizing its unhealthy tissues is a convenient tool in order to diagnose hepatic diseases and assess the response to the according treatments. In this work we propose a method to segment the liver and its lesions from Computed Tomography (CT) scans using Convolutional Neural Networks (CNNs), that have proven good results in a variety of computer vision tasks, including medical imaging. The network that segments the lesions consists of a cascaded architecture, which first focuses on the region of the liver in order to segment the lesion…
Institute of Computing Technology, Chinese Academy of Sciences（中国科学院计算技术研究所）；University of Chinese Academy of Sciences（中国科学院大学）；University of California, Los Angeles（加利福尼亚大学洛杉矶分校）；University of Southern California（南加利福尼亚大学）；Lenovo Research（联想研究院）；Lenovo Ltd.（联想有限公司）
Purpose: Automated liver tumor segmentation from Computed Tomography (CT) images is a necessary prerequisite in the interventions of hepatic abnormalities and surgery planning. However, accurate liver tumor segmentation remains challenging due to the large variability of tumor sizes and inhomogeneous texture. Recent advances based on Fully Convolutional Network (FCN) for medical image segmentation drew on the success of learning discriminative pyramid features. In this paper, we propose a Decoupled Pyramid Correlation Network (DPC-Net) that exploits attention mechanisms to fully leverage both …
SRMA-Mamba: Spatial Reverse Mamba Attention Network for Pathological Liver Segmentation in MRI Volumes
Chongqing University of Posts and Telecommunications（重庆邮电大学）；Biomedical Perception & Intelligence Lab, University of South Dakota（南达科他大学生物医学感知与智能实验室）；Aalto University（阿尔托大学）；Malaviya National Institute of Technology Jaipur（马拉维亚国家理工学院斋浦尔分校）；Machine & Hybrid Intelligence Lab, Northwestern University（西北大学机器与混合智能实验室）
Sun Yat-sen University（中山大学）；The First Affiliated Hospital, Sun Yat-sen University（中山大学附属第一医院）；Infervision Inc.（推想医疗科技股份有限公司）
Hepatocellular carcinoma (HCC) is the second most frequent cause of malignancy-related death and is one of the diseases with the highest incidence in the world. Because the liver is the only organ in the human body that is supplied by two major vessels: the hepatic artery and the portal vein, various types of malignant tumors can spread from other organs to the liver. And due to the liver masses' heterogeneous and diffusive shape, the tumor lesions are very difficult to be recognized, thus automatic lesion detection is necessary for the doctors with huge workloads. To assist doctors, this work…
Multi-modal Liver Segmentation and Fibrosis Staging Using Real-world MRI Images
Multiscale X-ray Imaging (MXI) Lab, Department of Mechanical Engineering, University College London（多尺度X射线成像实验室，机械工程系，伦敦大学学院）；Centre for Clinical Brain Sciences, University of Edinburgh（临床脑科学中心，爱丁堡大学）；MRC Weatherall Institute of Molecular Medicine, University of Oxford（MRC韦伯尔分子医学研究所，牛津大学）
Multi-target and multi-stage liver lesion segmentation and detection in multi-phase computed tomography scans
King Fahd University of Petroleum and Minerals（法赫德国王石油矿产大学）；Vinbrain JSC（Vinbrain股份公司）；Le Quy Don Technical University（黎贵敦技术大学）；University Medical Center at Ho Chi Minh City（胡志明市大学医疗中心）
Emory University（埃默里大学）；University of Chicago（芝加哥大学）；Georgia Institute of Technology（佐治亚理工学院）；Emory University School of Medicine（埃默里大学医学院）
This study proposed a deep learning-based tracking method for ultrasound (US) image-guided radiation therapy. The proposed cascade deep learning model is composed of an attention network, a mask region-based convolutional neural network (mask R-CNN), and a long short-term memory (LSTM) network. The attention network learns a mapping from a US image to a suspected area of landmark motion in order to reduce the search region. The mask R-CNN then produces multiple region-of-interest (ROI) proposals in the reduced region and identifies the proposed landmark via three network heads: bounding box re…
Tel Aviv University（特拉维夫大学）；The Chaim Sheba Medical Center（夏姆谢巴医疗中心）；Bar-Ilan University（巴伊兰大学）
Deep learning methods, and in particular convolutional neural networks (CNNs), have led to an enormous breakthrough in a wide range of computer vision tasks, primarily by using large-scale annotated datasets. However, obtaining such datasets in the medical domain remains a challenge. In this paper, we present methods for generating synthetic medical images using recently presented deep learning Generative Adversarial Networks (GANs). Furthermore, we show that generated medical images can be used for synthetic data augmentation, and improve the performance of CNN for medical image classificatio…
A No-Reference Medical Image Quality Assessment Method Based on Automated Distortion Recognition Technology: Application to Preprocessing in MRI-guided Radiotherapy
Beijing University of Posts and Telecommunications（北京邮电大学）；National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College（中国医学科学院北京协和医学院国家癌症中心/国家癌症临床医学研究中心/肿瘤医院）
AI generated annotations for Breast, Brain, Liver, Lungs and Prostate cancer collections in National Cancer Institute Imaging Data Commons
BAMF Health（BAMF健康公司）；National Institute of Health（美国国立卫生研究院）；Frederick National Laboratory for Cancer Research（弗雷德里克国家癌症研究实验室）；Brigham and Women’s Hospital（布莱根妇女医院）；Harvard Medical School（哈佛医学院）
INSA Centre Val de Loire（卢瓦尔河谷国立应用科学学院）；PRISME（PRISME实验室）
This paper addresses the problem of liver cancer segmentation in Whole Slide Image (WSI). We propose a multi-scale image processing method based on automatic end-to-end deep neural network algorithm for segmentation of cancer area. A seven-levels gaussian pyramid representation of the histopathological image was built to provide the texture information in different scales. In this work, several neural architectures were compared using the original image level for the training procedure. The proposed method is based on U-Net applied to seven levels of various resolutions (pyramidal subsumpling)…
SIAT, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）；The Chinese University of Hong Kong（香港中文大学）
Purpose: Segmentation of liver vessels from CT images is indispensable prior to surgical planning and aroused broad range of interests in the medical image analysis community. Due to the complex structure and low contrast background, automatic liver vessel segmentation remains particularly challenging. Most of the related researches adopt FCN, U-net, and V-net variants as a backbone. However, these methods mainly focus on capturing multi-scale local features which may produce misclassified voxels due to the convolutional operator's limited locality reception field. Methods: We propose a robust…
Identifying Signatures of Image Phenotypes to Track Treatment Response in Liver Disease
Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Austria（维也纳医科大学生物医学影像与影像引导治疗部门）；Institute of Clinical Epidemiology, Public Health, Health Economics, Medical Statistics and Informatics, Medical University of Innsbruck, Austria（因斯布鲁克医科大学临床流行病学、公共卫生、卫生经济学、医学统计与信息学研究所）；Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA（诺华制药公司，东汉诺威，新泽西州，美国）；Novartis Pharma AG, Basel, Switzerland（诺华制药集团，巴塞尔，瑞士）；Comprehensive Center for Artificial Intelligence in Medicine, Medical University of Vienna, Austria（医学人工智能综合中心，维也纳医科大学，奥地利）；Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Austria（消化内科与肝病科，医学第三部，维也纳医科大学，奥地利）；Medical University of Vienna, Waehringer Guertel 18–20, 1090 Vienna, Austria（维也纳医科大学，瓦尔希林格特尔18–20号，1090维也纳，奥地利）
Triple-Phase Sequential Fusion Network for Hepatobiliary Phase Liver MRI Synthesis
Yu-Yue Pathology Research Center, Jinfeng Laboratory（于越病理研究中心，锦峰实验室）；Department of Clinical Laboratory Medicine, The First Affiliated Hospital of Army Medical University（临床实验室医学部，陆军军医大学第一附属医院）；Laboratory of Intelligent Collaborative Computing, University of Electronic Science and Technology of China（智能协同计算实验室，电子科技大学）
James Cook University（詹姆斯·库克大学）；Mahidol University（玛希隆大学）；University of Bremen（不来梅大学）
Automatic segmentation of hepatic lesions in computed tomography (CT) images is a challenging task to perform due to heterogeneous, diffusive shape of tumors and complex background. To address the problem more and more researchers rely on assistance of deep convolutional neural networks (CNN) with 2D or 3D type architecture that have proven to be effective in a wide range of computer vision tasks, including medical image processing. In this technical report, we carry out research focused on more careful approach to the process of learning rather than on complex architecture of the CNN. We have…
Stanford University（斯坦福大学）；Varian Medical Systems（瓦里安医疗系统公司）；Huiyihuiying Medical Co（慧医慧影医疗公司）；Google Inc（谷歌公司）
Segmentation of livers and liver tumors is one of the most important steps in radiation therapy of hepatocellular carcinoma. The segmentation task is often done manually, making it tedious, labor intensive, and subject to intra-/inter- operator variations. While various algorithms for delineating organ-at-risks (OARs) and tumor targets have been proposed, automatic segmentation of livers and liver tumors remains intractable due to their low tissue contrast with respect to the surrounding organs and their deformable shape in CT images. The U-Net has gained increasing popularity recently for ima…
A-QCF-Net: An Adaptive Quaternion Cross-Fusion Network for Multimodal Liver Tumor Segmentation from Unpaired Datasets
University College of Engineering, Bharathidasan Institute of Technology Campus, Anna University（安娜大学工程学院，巴拉特拉桑理工学院校区，安娜大学）；National Institute of Technology（国家理工学院）
Comparative Study of UNet-based Architectures for Liver Tumor Segmentation in Multi-Phase Contrast-Enhanced Computed Tomography
School of Computer Science and Engineering（计算机科学与工程学院）；The Saigon International University（暹罗国际大学）；School of Biomedical Engineering（生物医学工程学院）；International University（国际大学）；Vietnam National University HCMC（越南国家大学胡志明市分校）
Automatic liver lesion segmentation is a challenging task while having a significant impact on assisting medical professionals in the designing of effective treatment and planning proper care. In this paper we propose a cascaded system that combines both 2D and 3D convolutional neural networks to effectively segment hepatic lesions. Our 2D network operates on a slice by slice basis to segment the liver and larger tumors, while we use a 3D network to detect small lesions that are often missed in a 2D segmentation design. We employ this algorithm on the LiTS challenge obtaining a Dice score per …
With the injection of contrast material into blood vessels, multi-phase contrasted CT images can enhance the visibility of vessel networks in the human body. Reconstructing the 3D geometric morphology of liver vessels from the contrasted CT images can enable multiple liver preoperative surgical planning applications. Automatic reconstruction of liver vessel morphology remains a challenging problem due to the morphological complexity of liver vessels and the inconsistent vessel intensities among different multi-phase contrasted CT images. On the other side, high integrity is required for the 3D…
Primary tumors have a high likelihood of developing metastases in the liver and early detection of these metastases is crucial for patient outcome. We propose a method based on convolutional neural networks (CNN) to detect liver metastases. First, the liver was automatically segmented using the six phases of abdominal dynamic contrast enhanced (DCE) MR images. Next, DCE-MR and diffusion weighted (DW) MR images are used for metastases detection within the liver mask. The liver segmentations have a median Dice similarity coefficient of 0.95 compared with manual annotations. The metastases detect…
China University of Petroleum（中国石油大学）；Qingdao Municipal Hospital（青岛市市立医院）；University of Chinese Academy of Sciences（中国科学院大学）
Liver cancer is one of the most common malignant diseases in the world. Segmentation and labeling of liver tumors and blood vessels in CT images can provide convenience for doctors in liver tumor diagnosis and surgical intervention. In the past decades, many state-of-the-art medical image segmentation algorithms appeared during this period. With the development of embedded devices, embedded deployment for medical segmentation and automatic reconstruction brings prospects for future automated surgical tasks. Yet, most of the existing segmentation methods mostly care about the spatial feature co…
Precise segmentation of the liver is critical for computer-aided diagnosis such as pre-evaluation of the liver for living donor-based transplantation surgery. This task is challenging due to the weak boundaries of organs, countless anatomical variations, and the complexity of the background. Computed tomography (CT) scanning and magnetic resonance imaging (MRI) images have different parameters and settings. Thus, images acquired from different modalities differ from one another making liver segmentation challenging task. We propose an efficient liver segmentation with the combination of holist…
Motion-robust 2D Radial Turbo Spin Echo (RADTSE) pulse sequence can provide a high-resolution composite image, T2-weighted images at multiple echo times (TEs), and a quantitative T2 map, all from a single k-space acquisition. In this work, we use a deep-learning convolutional neural network (CNN) for the segmentation of liver in abdominal RADTSE images. A modified UNET architecture with generalized dice loss objective function was implemented. Three 2D CNNs were trained, one for each image type obtained from the RADTSE sequence. On evaluating the performance of the CNNs on the validation set, …
Institute of Computing Technology, Chinese Academy of Sciences（中国科学院计算技术研究所）；University of Chinese Academy of Sciences（中国科学院大学）；Lenovo Research（联想研究院）
Liver tumor segmentation plays an important role in hepatocellular carcinoma diagnosis and surgical planning. In this paper, we propose a novel Semantic Feature Attention Network (SFAN) for liver tumor segmentation from Computed Tomography (CT) volumes, which exploits the impact of both low-level and high-level features. In the SFAN, a Semantic Attention Transmission (SAT) module is designed to select discriminative low-level localization details with the guidance of neighboring high-level semantic information. Furthermore, a Global Context Attention (GCA) module is proposed to effectively fus…
School of Automation, Harbin University of Science and Technology（哈尔滨理工大学自动化学院）；Rongcheng College, Harbin University of Science and Technology（哈尔滨理工大学荣成学院）
Purpose: This paper proposes a new network framework called EAR-U-Net, which leverages EfficientNetB4, attention gate, and residual learning techniques to achieve automatic and accurate liver segmentation. Methods: The proposed method is based on the U-Net framework. First, we use EfficientNetB4 as the encoder to extract more feature information during the encoding stage. Then, an attention gate is introduced in the skip connection to eliminate irrelevant regions and highlight features of a specific segmentation task. Finally, to alleviate the problem of gradient vanishment, we replace the tra…
PAII Inc.（PAII公司）；Chang Gung Memorial Hospital（长庚纪念医院）；Vanderbilt University（范德堡大学）；PingAn Technology（平安科技）
Ultrasound (US) is a critical modality for diagnosing liver fibrosis. Unfortunately, assessment is very subjective, motivating automated approaches. We introduce a principled deep convolutional neural network (CNN) workflow that incorporates several innovations. First, to avoid overfitting on non-relevant image features, we force the network to focus on a clinical region of interest (ROI), encompassing the liver parenchyma and upper border. Second, we introduce global heteroimage fusion (GHIF), which allows the CNN to fuse features from any arbitrary number of images in a study, increasing its…
Vanderbilt University（范德堡大学）；Vanderbilt University Medical Center（范德堡大学医学中心）；Wake Forest School of Medicine（维克森林大学医学院）
Manually tracing regions of interest (ROIs) within the liver is the de facto standard method for measuring liver attenuation on computed tomography (CT) in diagnosing nonalcoholic fatty liver disease (NAFLD). However, manual tracing is resource intensive. To address these limitations and to expand the availability of a quantitative CT measure of hepatic steatosis, we propose the automatic liver attenuation ROI-based measurement (ALARM) method for automated liver attenuation estimation. The ALARM method consists of two major stages: (1) deep convolutional neural network (DCNN)-based liver segme…
Anisotropic Hybrid Networks for liver tumor segmentation with uncertainty quantification
Univ. Grenoble Alpes（格勒诺布尔大学）；Inserm（法国国家健康与医学研究院）；Grenoble Institut Neurosciences（格勒诺布尔神经科学研究所）；Pixyl（Pixyl公司）；Research and Development Laboratory（研发实验室）；Inria（法国国家信息与自动化研究所）；CNRS（法国国家科学研究中心）；Grenoble INP（格勒诺布尔综合理工学院）；LJK（格勒诺布尔大学联合实验室（注：因LJK无明确对应中文通用名称，按原文保留英文缩写））
Rutgers University（罗格斯大学）；Rutgers Robert Wood Johnson Medical School（罗格斯罗伯特·伍德·约翰逊医学院）
Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver diseases (CLD) which can progress to liver cancer. The severity and treatment of NAFLD is determined by NAFLD Activity Scores (NAS)and liver fibrosis stage, which are usually obtained from liver biopsy. However, biopsy is invasive in nature and involves risk of procedural complications. Current methods to predict the fibrosis and NAS scores from noninvasive CT images rely heavily on either a large annotated dataset or transfer learning using pretrained networks. However, the availability of a large anno…
